Hypolipidemic Effect of Green Tea Leaves through Induction of Antioxidant and Phase II Enzymes Including Superoxide Dismutase, Catalase, and Glutathione S-Transferase in Rats

Journal of Agricultural and Food Chemistry

Volumn 46, Issue 5, 1998, Pages 1893-1899

  Lin, Yu Li ^a   Cheng, Chong Yurn ^a   Lin, Ya Ping ^a   Lau, Yong Wei ^a   Juan, I Ming ^b   Lin, Jen Kun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b Taiwan Tea Experiment Station   (Taiwan)

Author keywords

GST; HDL C; Hypolipidemic; LDL C; Longjing tea; Phase ii enzyme; SOD

Indexed keywords

EID: 0001639328     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Agarwal, R.; Katiyar, S. K.; Zaidi, S. I. A.; Mukhtar, H. Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives. Cancer Res. 1992, 52, 3582-3588.
2. Bedwell, S.; Dean, R. T.; Jessup, W. The action of defined oxygen-centred free radicals on human low-density lipoprotein. Biochem. J. 1989, 6 (1), 67-75.
3. Bu-Abbas, A.; Clifford, M. N.; Ioannides, C.; Walker, R. Stimulation of rat hepatic UDP-glucuronosyl transferase activity following treatment with green tea. Food Chem. Toxicol. 1995, 33, 27-30.
4. Caraco, Y.; Zylber-Katz, E.; Berry, E. M.; Levy, M. Caffeine pharmacokinetics in obesity and following significant weight reduction. Int. J. Obesity Relat. Metab. Disorders 1995, 19, 234-239.
5. Chisaka, T.; Matsuda, H.; Kubomura, Y.; Mochizuki, M.; Yamahara, J.; Fujimura, H. The effect of crude drugs on experimental hypercholesteremia: mode of action of (-)-epigallocatechin gallate tea leaves. Chem. Pharm. Bull. 1988, 36, 227-233.
6. Esterbauer, H.; Jürgens, G.; Quehenberger, O.; Koller, E. Autoxidation of human low-density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes J. Lipid Res. 1987, 28, 49.
7. Esterbauer, H.; Hermann, E.; Striegel, G.; Puhl, H.; Rotheneder, M. Continuous monitoring of in vitro oxidation of human low-density lipoprotein. Free Radical Res. Commun. 1989, 6, 67.
8. Graham, A.; Hogg, N.; Kalyanaraman, B.; Q'Leary, V.; Darley-Usmar, V.; Moneada, S. Peroxynitrite modification of lowdensity lipoprotein leads to recognition by the macrophage scavenger receptor. FEBS Lett. 1993, 330, 181-185.
9. Habig, W. H.; Pabst, M. J.; Jokoby, W. B. Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249, 7130-7139.
10. Hampton, M. G. Production of black tea. In Tea: Cultivation to Consumption; Willson, K. C., Clifford, M. N., Eds.; Chapman & Hall: London, U.K., 1992; pp 459-511.
11. Hertog, M. G. L.; Hollman, P. C. H.; Putte, B. van de. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices. J. Agric. Food Chem. 1993, 41, 1242-1246.
12. Ho, C.-T.; Chen, Q.; Shi, H.; Zhang, K.-Q.; Rosen, R. T. Antioxidative effect of polyphenol extract prepared from various Chinese teas. Prev. Med. 1992, 21, 520-525.
13. Hollman, P. C. H.; Hertog, M. G. L.; Katan, M. B. Role of dietary flavonoids in protection against cancer and coronary heart disease. Biochem. Soc. Trans. 1996, 24, 785-789.
14. Ikeda, I.; Imasato, Y.; Sasaki, E.; Nakayama, M.; Nagao, H.; Takeo, T.; Yayabe, F.; Sugano, M. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. Biochim. Biophys. Acta 1992, 1127, 141-146.
15. Jacob, R. A.; Burri, B. J. Oxidative damage and defense. Am. J. Clin. Nutr. 1998, 63, 985S-990S.
16. Juch, R. J.; Cheng, S. J.; Klaunig, J. E. Prevention of cytotoxicity and inhibition of intracellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 1989, 10, 1003-1008.
17. Katiyar, S. K.; Agarwal, R.; Zaim, M. T.; Mukhtar, H. Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea. Carcinogenesis 1993, 14, 849-855.
18. Katiyar, S. K.; Agarwal, R.; Mukhtar, H. Inhibition of spontaneous and photo-enhance lipid peroxidation in mouse epidermal microsomes by epicatechin derivatives from green tea. Cancer Lett. 1994, 79, 61-66.
19. Khan, S. G.; Katiyar, S. K.; Agarwal, R.; Mukhtar, H. Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention. Cancer Res. 1992, 52, 4050-4052.
20. Lairon, D. Dietary fibres: effects on lipid metabolism and mechanisms of action. Eur. J. Clin. Nutr. 1996, 50, 125-133.
21. Lea, M. A.; Xiao, Q.; Sadhukhan, A. K.; Cottle, S.; Wang, Z.-Y.; Yang C. S. Inhibitory effects of tea extract and (-)-epigallocatechin gallate on DNA synthesis and proliferation of hepatoma and erythroleukemia cells. Cancer Lett. 1993, 65, 231-236.
22. Lee, S. F.; Liang, Y. C.; Lin, J. K. Inhibition of 1,2,4-benzenetriol-generated active oxygen species and induction of phase II enzymes by green tea polyphenols. Chem.-Biol. Interactions 1995, 98, 283-301.
23. κB. Mol. Pharmacol. 1997, 52, 465-472.
24. Lin, Y.-L.; Juan, I.-M.; Chen, Y.-L.; Liang, Y.-C.; Lin, J.-K. Composition of polyphenols in fresh tea leaves and associations of their oxygen-radical-absorbing capacity with antiproliferative actions in fibroblast cells. J. Agric. Food Chem. 1996, 44, 1387-1394.
25. Luo, M.; Kannar, K.; Wahlqvist, M. L.; O'Brien, R. C. Inhibition of LDL oxidation by green tea extract. Lancet 1997, 349, 360-361.
26. Mangiapane, H.; Thomson, J.; Salter, A,; Brown, S.; Bell, G. D.; White, D. A. The inhibition of the oxidation of low density lipoprotein by (+)-catechin, a naturally occurring flavonoid. Biochem. Pharmacol. 1992, 43, 446-450.
27. McDord, J. M.; Fridovich, I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 1969, 244, 6049-6055.
28. 2+ mediated oxidative modification of low-density lipoprotein. Biol Pharm. Bull. 1994, 17, 1567-1572.
29. Muramatsu, K.; Fukuyo, M.; Hara, Y. Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. J. Nutr. Sci. Vitaminol. 1986, 32, 613-622.
30. Nakagawa, K.; Miyazawa, T. Chemiluminescence-high-performance liquid chromatographic determination of tea catechin, (-)-epigallocatechin-3-gallate. at picomole levels in rat and human plasma. Anal. Biochem. 1997, 248, 441-49.
31. Nakamura, M.; Kawabata, T. Effect of Japanese green tea on nitrosamine formation in vitro. J. Food Sci. 1981, 46, 306-307.
32. Nakane, H.; Ono, K. Differential inhibitory effects of some catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and cellular deoxyribonucleic and ribonucleic acid polymerases. Biochemistry 1990, 29, 2841-2845.
33. Nebot, C.; Moutet, M.; Huet, P.; Xu, J.-Z.; Yadan, J.-C.; Chaudiere, J. Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol. Anal. Biochem. 1993, 214, 442-451.
34. Oguni, I.; Nasu, K.; Yamamoto, S.; Nomura, T. On the antitumor activity of fresh green tea leaf. Agric. Biol. Chem. 1988, 52, 1879-1880.
35. Pannala, A.; Rice-Evans, C. A., Halliwell, B.; Singh, S. Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols. Biochem. Biophys. Res. Commun. 1997, 232, 164-168.
36. Perchellet, J.; Perchellet, E. M. Antioxidants and multistage carcinogenesis in mouse skin. Free Radical Biol. Med. 1989, 7, 377-408.
37. Persijin, J. P.; van der Slik, W. A new method for the determination of serum γ-glutamyltranspeptidase. J. Clin. Chem. Clin. Biochem. 1976, 14, 42-48.
38. Poppel, G. V.; Berg, H. V.-D. Vitamins and cancer. Cancer Lett. 1997, 114, 195-202.
39. Reaven, P. D.; Witztum, J. L. Oxidized low-density lipoproteins in atherogenesis: role of dietary modification. Annu. Rev. Nutr. 1996, 16, 51-71.
40. Reiners, J. J., Jr.; Kodari, E.; Cappel, R. E.; Gilbert, H. F. Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoyl phorbol-13-acetate and throughout the ontogeny of skin ceancer. Part II: Quantitation of glutathione and glutathione disulfide. Carcinogenesis 1991a, 12, 2345-2352.
41. Reiners, J. J., Jr.; Thai, G.; Rupp, T.; Cantu, A. R. Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoyl phorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of Superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase. Carcinogenesis 1991b, 12, 2337-2343.
42. Reitman, S.; Frankel, S. A colorimetric method for the determination of serum GOT and GPT. Am. J. Clin. Pathol. 1957, 28, 57-60.
43. Rodenas, J.; Mitavila, M. T.; Carbonell, T. Stimultaneous generation of nitric oxide and superoxide by inflammatory cells in rats. Free Radical Biol. Med. 1995, 18, 869-875.
44. Shi, S. T.; Wang, Z.-Y.; Smith, T. J.; Hong, J.-Y.; Chen, W.-F.; Ho, C.-T.; Yang, C. S. Effects of green tea and black tea on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation, DNA methylation, and lung tumorigenesis in A/J mice. Cancer Res. 1994, 54, 4641-4647.
45. Shiraki, M.; Hara, Y.; Osawa, T.; Kumon, H.; Nakauama, T.; Kawakishi, S. Antioxidative and antimutagenic effects of theaflavins from black tea. Mutat. Res. 1994, 323, 29-34.
46. Siedel, J.; Mollering, H.; Ziegenhorn, J. Sensitive color reagent for the enzymatic determination of creatinine. Clin. Chem. 1984, 30 968.
47. Spurlock, M. E.; Hahn, K. J.; Miner, J. L. Regulation of adipsin and body composition in the monosodium glutamate (MSG)-treated mouse. Physiol. Behav. 1996, 60, 1217-1221.
48. Steinberg, D. Low-density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 1997, 272, 20963-20966.
49. Sun, J.; Giraud, D. W.; Moxley, R. A.; Driskell, J. A. β-Carotene and α-tocopherol inhibit the development of atherosclerotic lesions in hypercholesterolemic rabbits. Int. J. Vitamin Nutr. Res. 1997, 67, 155-63.
50. Sun, Y. Free radical, antioxidant enzymes, and carcinogenesis. Free Radical Biol. Med. 1990, 8, 583-599.
51. Takeo, T. Green and semi-fermented teas. In Tea: Cultivation to Consumption; Willson, K. C., Clifford, M. N., Eds.; Chapman & Hall: London, U.K., 1992; pp 413-457.
52. Truswell A. S. Dietary fibre and blood lipids. Curr. Opin. Lipidol. 1995, 6, 14-19.
53. Wang, Z.-Y,; Cheng, S. J.; Zhou, Z. C.; Athar, M.; Khan, W. A.; Bickers, D. R.; Mukhtar, H. Antimutagenic activity of green tea polyphenols. Mutat. Res. 1989, 223, 273-285.
54. Wang, Z.-Y.; Huang, M.-T.; Ferraro, T.; Wong, C.-Q.; Lou, Y.-R.; Reuhl, K.; Iatropoulos, M.; Yang, C. S.; Conney, A. H. Inhibitory effect of green tea in thr drinking tumorigenesis by ultravilote light and 12-Q-tetradecan-oylphorbol-13-acetate in the skin of SKH-1 mice. Cancer Res. 1992, 52, 1162-1170.
55. Yang, C. S.; Wang, Z. Y. Tea and cancer. J. Natl. Cancer Inst. 1993, 55, 1038-1049.
56. Yen, G.-C.; Chen, H.-Y. Antioxidant activity of various tea extracts in relation to their antimutagenicity. J. Agric. Food Chem. 1995, 43, 27-32.