Yeast mutants affecting possible quality control of plasma membrane proteins

Molecular and Cellular Biology

Volumn 19, Issue 5, 1999, Pages 3588-3599

  Li, Y U ^a   Kane, Thomas ^a   Tipper, Christopher ^a   Spatrick, Phyllis ^a   Jenness, Duane D ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CARBOXYPEPTIDASE C; CHLORIDE CHANNEL; MATING HORMONE ALPHA FACTOR; MEMBRANE PROTEIN; PERMEASE; TUMOR PROTEIN;

ARTICLE; CELL MEMBRANE; CELL VACUOLE; GENE MUTATION; GENE REPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; TEMPERATURE SENSITIVITY;

SACCHAROMYCES CEREVISIAE;

EID: 0032941754     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.5.3588     Document Type: Article

References (60)

1. Anderson, M. T., I. M. Tjioe, M. C. Lorincz, D. R. Parks, L. A. Herzenberg, G. P. Nolan, and L. A. Herzenberg. 1996. Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. Proc. Natl. Acad. Sci. USA 93:8508-8511.
2. 2+ ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol. Biol. Cell 3:633-654.
3. Babst, M., and S. Emr. Personal communication.
4. Babst, M., B. Wendland, E. J. Estepa, and S. D. Emr. 1998. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17:2982-2993.
5. Biwersi, J., N. Emans, and A. S. Verkman. 1996. Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo. Proc. Natl. Acad. Sci. USA 93:12484-12489.
6. +]ATPaSe: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J. Cell Biol. 128:39-49.
7. Cooper, A. A., and T. H. Stevens. 1996. Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol. 133:529-541.
8. Davis, N. G., J. L. Horecka, and G. F. Sprague, Jr. 1993. cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122:53-65.
9. Futter, C. E., A. Pearse, L. J. Hewlett, and C. R. Hopkins. 1996. Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J. Cell Biol. 132:1011-1023.
10. Gaxiola, R. A., D. S. Yuan, R. D. Klausner, and G. R. Fink. 1998. The yeast CLC chloride channel functions in cation homeostasis. Proc. Natl. Acad. Sci. USA 95:4046-4050.
11. Gerdes, H.-H., and C. Kaether. 1996. Green fluorescent protein: applications in cell biology. FEBS Lett. 389:44-47.
12. Greene, J. R., N. H. Brown, B. J. DiDomenico, J. Kaplan, and D. J. Eide. 1993. The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth. Mol. Gen. Genet. 241:542-553.
13. Hartwell, L. H. 1980. Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone. J. Cell Biol. 85:811-822.
14. Hechenberger, M., B. Schwappach, W. N. Fischer, W. B. Frommer, T. J. Jentsch, and K. Steinmeyer. 1996. A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. J. Biol. Chem. 271:33632-33638.
15. Hicke, L., and H. Riezman. 1996. Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84:277-287.
16. Hirschman, J., G. DeZutter, W. Simonds, and D. D. Jenness. 1997. The Gβγ complex of the yeast pheromone response pathway: subcellular fractionation and protein-protein interaction. J. Biol. Chem. 272:240-248.
17. Hong, E., A. R. Davidson, and C. A. Kaiser. 1996. A pathway for targeting soluble misfolded proteins to the yeast vacuole. J. Cell Biol. 135:623-633.
18. Hsu, V. W., L. C. Yuan, J. G. Nuchtern, J. Lippincott-Schwartz, G. J. Hammerling, and R. D. Klausner. 1991. A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules. Nature 352:441-444.
19. Hwa, J., P. Garriga, X. Liu, and H. G. Khorana. 1997. Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. Proc. Natl. Acad. Sci. USA 94:10571-10576.
20. Jenness, D. D., B. S. Goldman, and L. H. Hartwell. 1987. Saccharomyces cerevisiae mutants unresponsive to α-factor pheromone: α-factor binding and extragenic suppression. Mol. Cell. Biol. 7:1311-1319.
21. Jenness, D. D., V. Li, C. Tipper, and S. Spatrick. 1997. Elimination of defective α-factor pheromone receptors. Mol. Cell. Biol. 17:6236-6245.
22. Jenness, D. D., and P. Spatrick. 1986. Down regulation of the α-factor pheromone receptor in S. cerevisiae. Cell 46:345-353.
23. Jones, E. W., G. C. Webb, and M. A. Hiller. 1997. Biogenesis and function of the yeast vacuole, p. 363-470. In J. R. Pringle, J. R. Broach, and E. W. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. III. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
24. Katz, M. E., J. Ferguson, and S. I. Reed. 1987. Temperature-sensitive lethal pseudorevertants of ste mutations in Saccharomyces cerevisiae. Genetics 115: 627-636.
25. Kaushal, S., and H. G. Khorana. 1994. Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry 33:6121-6128.
26. Konopka, J. B., D. D. Jenness, and L. H. Hartwell. 1988. The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone. Cell 54:609-620.
27. Kopito, R. R. 1997. ER quality control: the cytoplasmic connection. Cell 88: 427-430.
28. Kubler, E., and H. Riezman. 1993. Actin and fimbrin are required for the internalization step of endocytosis. EMBO J. 12:2855-2862.
29. Li, L., and S. N. Cohen. 1996. Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell 85:319-329.
30. Luo, W., and A. Chang. 1997. Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J. Cell Biol. 138:731-746.
31. Lupas, A. 1996. Predictions and analysis of coiled-coil structures. Methods Enzymol. 266:513-525.
32. Marcusson, E. G., B. F. Horazdovsky, J. L. Cereghino, E. Gharakhanian, and S. D. Emr. 1994. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77:579-586.
33. Minami, Y., A. M. Weissman, L. E. Samelson, and R. D. Klausner. 1987. Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor. Proc. Natl. Acad. Sci. USA 84:2688-2692.
34. Newlon, C. S., L. R. Lipchitz, I. Collins, A. Deshpande, R. J. Devenish, R. P. Green, H. L. Klein, T. G. Palzkill, R. B. Ren, S. Synn, and S. T. Woody. 1991. Analysis of a circular derivative of Saccharomyces cerevisiae chromosome III: a physical map and identification and localization of ARS elements. Genetics 129:343-357.
35. Oliver, S. G., Q. J. van der Aart, M. L. Agostoni-Carbone, M. Aigle, L. Alberghina, D. Alexandraki, G. Antoine, R. Anwar, J. P. Ballesta, P. Benit, G. Berben, E. Bergantino, N. Biteau, P. A. Bolle, M. Bolotinfukuhara, A. Brown, A. J. P. Brown, J. M. Buhler, C. Carcano, G. Carignani, H. Cederberg, R. Chanet, R. Contreras, M. Crouzet, B. Daignanfornier, E. Defoor, M. Delgado, J. Demolder, C. Doira, E. Dubois, B. Dujon, and A. Dusterhoft. 1992. The complete DNA sequence of yeast chromosome III. Nature 357: 38-46.
36. Ormö, M., A. B. Cubitt, K. Kallio, L. A. Gross, R. Y. Tsien, and S. J. Remington. 1996. Crystal structure of the Aequorea victoria green fluorescent protein. Science 273:1392-1395.
37. Parlati, F., M. Dominguez, J. J. M. Bergeron, and D. Y. Thomas. 1995. Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus. J. Biol. Chem. 270:244-253.
38. Piper, R. C., A. A. Cooper, H. Yang, and T. H. Stevens. 1995. VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol. 131:603-617.
39. Raymond, C. K., I. Howaldstevenson, C. A. Vater, and T. H. Stevens. 1992. Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class-E vps mutants. Mol. Biol. Cell 3:1389-1402.
40. Raymond, C. K., P. J. O'Hara, G. Eichinger, J. H. Rothman, and T. H. Stevens. 1990. Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J. Cell Biol. 111:877-892.
41. Rieder, S. E., L. M. Banta, K. Kohrer, J. M. McCaffery, and S. D. Emr. 1996. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant, Mol. Biol. Cell 7:985-999.
42. Rieder, S. E., and S. D. Emr. 1997. A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol. Biol. Cell 8:2307-2327.
43. Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243.
44. Roth, A. F., and N. G. Davis. 1996. Ubiquitination of the yeast a-factor receptor. J. Cell Biol. 134:661-674.
45. Rybak, S. L., F. Lanni, and R. F. Murphy. 1997. Theoretical considerations on the role of membrane potential in the regulation of endosomal pH. Biophys. J. 73:674-687.
46. Schandel, K. A., and D. D. Jenness. 1994. Direct evidence for ligand-induced internalization of the yeast α-factor pheromone receptor. Mol. Cell. Biol. 14: 7245-7255.
47. Singerkruger, B., H. Stenmark, A. Dusterhoft, P. Philippsen, J. S. Yoo, D. Gallwitz, and M. Zerial. 1994. Role of three rab5-like Gtpases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J. Cell Biol. 125:283-298.
48. Singerkruger, B., H. Stenmark, and M. Zerial. 1995. Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway. J. Cell Sci. 108:3509-3521.
49. Sprague, G. F., Jr., and I. Herskowitz. 1981. Control of yeast cell type by the mating type locus. I. Identification and control of expression of the a-specific gene BAR1. J. Mol. Biol. 153:305-321.
50. Symington, L. S., A. Brown, S. G. Oliver, P. Greenwell, and T. D. Petes. 1991. Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics 128:717-727.
51. Takeshige, K., M. Baba, S. Tsuboi, T. Noda, and Y. Ohsumi. 1992. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119:301-311.
52. Trowbridge, I. S., J. F. Collawn, and C. R. Hopkins. 1993. Signal-dependent membrane protein trafficking in the endocytic pathway. Annu. Rev. Cell Biol. 9:129-161.
53. Van Dyke, R. W. 1988. Proton pump-generated electrochemical gradients in rat liver multivesicular bodies. Quantitation and effects of chloride. J. Biol. Chem. 263:2603-2611.
54. Vida, T. A., and S. D. Emr. 1995. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J. Cell Biol. 128:779-792.
55. Vida, T. A., G. Huyer, and S. D. Emr. 1993. Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. J. Cell Biol. 121:1245-1256.
56. Vieira, A. V., C. Lamaze. and S. L. Schmid. 1996. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274:2086-2089.
57. Wilcox, C. A., K. Redding, R. Wright, and R. S. Fuller. 1992. Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol. Biol. Cell 3:1353-1371.
58. Wurmser, A. E., and S. D. Emr. 1998. Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. EMBO J. 17:4930-4942.
59. Xie, W., L. Li, and S. N. Cohen. 1998. Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc. Natl. Acad. Sci. USA 95:1595-1600.
60. Zhong, Q., C. F. Chen, Y. Chen, P. L. Chen, and W. H. Lee. 1997. Identification of cellular TSG101 protein in multiple human breast cancer cell lines. Cancer Res. 57:4225-4228.