Colon-specific delivery of prednisolone-appended α-cyclodextrin conjugate: Alleviation of systemic side effect after oral administration

Journal of Controlled Release

Volumn 79, Issue 1-3, 2002, Pages 103-112

  Yano, Hideki ^a   Hirayama, Fumitoshi ^a   Kamada, Makoto ^a   Arima, Hidetoshi ^a   Uekama, Kaneto ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Anti inflammatory effect; Colon specific delivery; Prednisolone; Prednisolone appended cyclodextrin; Systemic side effect

Indexed keywords

CYCLODEXTRIN; PREDNISOLONE; PREDNISOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON; CONTROLLED STUDY; DELAYED RELEASE FORMULATION; DRUG ABSORPTION; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENTERITIS; INFLAMMATION; LARGE INTESTINE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; STOMACH; THYMUS ATROPHY;

ADMINISTRATION, ORAL; ALPHA-CYCLODEXTRINS; ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS; COLON; CYCLODEXTRINS; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; MALE; PREDNISOLONE; PRODRUGS; RATS; RATS, WISTAR;

EID: 0037133114     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00532-6     Document Type: Article

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