A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G- protein coupling

FASEB Journal

Volumn 12, Issue 14, 1998, Pages 1461-1471

  Biebermann, Heike ^a,b   Schöneberg, Torsten ^a   Schulz, Angela ^a   Krause, Gerd ^c   Grüters, Annette ^b   Schultz, Günter ^a   Gudermann, Thomas ^a,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

G protein coupled receptor; Molecular modeling; Receptor conformation; Thyroid; TSH receptor allele

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; THYROTROPIN RECEPTOR; TYROSINE;

ALLELE; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CELL STIMULATION; DRUG RECEPTOR BINDING; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROLYSIS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; THYROID HORMONE SYNTHESIS;

EID: 0031790855     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.12.14.1461     Document Type: Article

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