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Volumn 31, Issue 1, 2005, Pages 13-24

High-avidity CD8+ T cells: Optimal soldiers in the war against viruses and tumors

Author keywords

Avidity; CD8+; Regulation; T cells; Tumors; Viral clearance

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN;

EID: 11244299387     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:31:1:13     Document Type: Review
Times cited : (70)

References (49)
  • 1
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller MA, Leggatt GR, Berzofsky JA: Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci USA 1996;93:4102-4107.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4102-4107
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 2
    • 0034130519 scopus 로고    scopus 로고
    • In vivo induction of a high-avidity, high-frequency cytotoxic T- lymphocyte response is associated with antiviral protective immunity
    • Sedlik C, Dadaglio G, Saron MF, Deriaud E, Rojas M, Casal SI, Leclerc C: In vivo induction of a high-avidity, high-frequency cytotoxic T- lymphocyte response is associated with antiviral protective immunity. J Virol 2000;74:5769-5775.
    • (2000) J Virol , vol.74 , pp. 5769-5775
    • Sedlik, C.1    Dadaglio, G.2    Saron, M.F.3    Deriaud, E.4    Rojas, M.5    Casal, S.I.6    Leclerc, C.7
  • 3
    • 0032543212 scopus 로고    scopus 로고
    • Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides
    • Gallimore A, Dumrese T, Hengartner H, Zinkernagel RM, Rammensee HG: Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. J Exp Med 1998;187:1647-1657.
    • (1998) J Exp Med , vol.187 , pp. 1647-1657
    • Gallimore, A.1    Dumrese, T.2    Hengartner, H.3    Zinkernagel, R.M.4    Rammensee, H.G.5
  • 4
    • 2242419092 scopus 로고    scopus 로고
    • Direct link between MHC polymorphism, T cell avidity, and diversity in immune defense
    • Messaoudi I, Guevara Patino JA, Dyall R, LeMaoult J, Nikolich-Zugich J: Direct link between MHC polymorphism, T cell avidity, and diversity in immune defense. Science 2002;298:1797-1800.
    • (2002) Science , vol.298 , pp. 1797-1800
    • Messaoudi, I.1    Guevara Patino, J.A.2    Dyall, R.3    LeMaoult, J.4    Nikolich-Zugich, J.5
  • 5
    • 0035423121 scopus 로고    scopus 로고
    • Heterogeneous T-cell response to MAGE-A 10(254-262): High-avidity- specific cytolytic T lymphocytes show superior antitumor activity
    • Dutoit V, Rubio-Godoy V, Dietrich PY, Quiqueres AL, Schnuriger V, Rimoldi D, et al.: Heterogeneous T-cell response to MAGE-A 10(254-262): high-avidity-specific cytolytic T lymphocytes show superior antitumor activity. Cancer Res 2001;61:5850-5856.
    • (2001) Cancer Res , vol.61 , pp. 5850-5856
    • Dutoit, V.1    Rubio-Godoy, V.2    Dietrich, P.Y.3    Quiqueres, A.L.4    Schnuriger, V.5    Rimoldi, D.6
  • 6
    • 0033558363 scopus 로고    scopus 로고
    • Isolation of high-avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers
    • Yee C, Savage PA, Lee PP, Davis MM, Greenberg PD: Isolation of high-avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers. J Immunol 1999;162:2227-2234.
    • (1999) J Immunol , vol.162 , pp. 2227-2234
    • Yee, C.1    Savage, P.A.2    Lee, P.P.3    Davis, M.M.4    Greenberg, P.D.5
  • 8
    • 0242495753 scopus 로고    scopus 로고
    • Cutting edge: Predetermined avidity of human CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres
    • Walter S, Herrgen L, Schoor O, Jung G, Wernet D, Buhring HJ, Rammensee HG, Stevanovic S: Cutting edge: predetermined avidity of human CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres. J Immunol 2003;171:4974-4978.
    • (2003) J Immunol , vol.171 , pp. 4974-4978
    • Walter, S.1    Herrgen, L.2    Schoor, O.3    Jung, G.4    Wernet, D.5    Buhring, H.J.6    Rammensee, H.G.7    Stevanovic, S.8
  • 9
    • 0035451399 scopus 로고    scopus 로고
    • Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: Correlation with CD8αβ versus CD8αα expression
    • Cawthon AG, Lu H, Alexander-Miller MA: Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8αβ versus CD8αα expression. J Immunol 2001;167:2577-2584.
    • (2001) J Immunol , vol.167 , pp. 2577-2584
    • Cawthon, A.G.1    Lu, H.2    Alexander-Miller, M.A.3
  • 10
    • 0035253434 scopus 로고    scopus 로고
    • High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL
    • Derby M, Alexander-Miller M, Tse R, Berzofsky J: High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL. J Immunol 2001;166: 1690-1697.
    • (2001) J Immunol , vol.166 , pp. 1690-1697
    • Derby, M.1    Alexander-Miller, M.2    Tse, R.3    Berzofsky, J.4
  • 11
    • 0042386735 scopus 로고    scopus 로고
    • Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus
    • Mealey RH, Zhang B, Leib SR, Littke MH, McGuire TC: Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus. Virology 2003;313:537-552.
    • (2003) Virology , vol.313 , pp. 537-552
    • Mealey, R.H.1    Zhang, B.2    Leib, S.R.3    Littke, M.H.4    McGuire, T.C.5
  • 12
    • 0033556322 scopus 로고    scopus 로고
    • High-avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    • Zeh HJ, III, Perry-Lalley D, Dudley ME, Rosenberg SA, Yang JC: High-avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy. J Immunol 1999;162:989-994.
    • (1999) J Immunol , vol.162 , pp. 989-994
    • Zeh III, H.J.1    Perry-Lalley, D.2    Dudley, M.E.3    Rosenberg, S.A.4    Yang, J.C.5
  • 13
    • 0033557173 scopus 로고    scopus 로고
    • T cell affinity maturation by selective expansion during infection
    • Busch DH, Pamer EG: T cell affinity maturation by selective expansion during infection. J Exp Med 1999;189:701-710.
    • (1999) J Exp Med , vol.189 , pp. 701-710
    • Busch, D.H.1    Pamer, E.G.2
  • 14
    • 0029013301 scopus 로고
    • Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR
    • al Ramadi BK, Jelonek MT, Boyd LF, Margulies DH, Bothwell AL: Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR. J Immunol 1995;155:662-673.
    • (1995) J Immunol , vol.155 , pp. 662-673
    • Al Ramadi, B.K.1    Jelonek, M.T.2    Boyd, L.F.3    Margulies, D.H.4    Bothwell, A.L.5
  • 15
    • 0037047079 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution
    • Echchakir H, Dorothee G, Vergnon I, Menez J, Chouaib S, Mami-Chouaib F: Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution. Proc Natl Acad Sci USA 2002; 99:9358-9363.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9358-9363
    • Echchakir, H.1    Dorothee, G.2    Vergnon, I.3    Menez, J.4    Chouaib, S.5    Mami-Chouaib, F.6
  • 16
    • 0037029652 scopus 로고    scopus 로고
    • Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic Hepatitis B virus infection
    • Reignat S, Webster GJM, Brown D, Ogg GS, King A, Seneviratne SL, et al.: Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic Hepatitis B virus infection. J Exp Med 2002;195: 1089-1101.
    • (2002) J Exp Med , vol.195 , pp. 1089-1101
    • Reignat, S.1    Webster, G.J.M.2    Brown, D.3    Ogg, G.S.4    King, A.5    Seneviratne, S.L.6
  • 18
    • 0035158340 scopus 로고    scopus 로고
    • Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR
    • Lawson TM, Man S, Wang ECY, Williams S, Amos N, Gillespie GM, et al.: Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR. Int Immunol 2001;13:1383-1390.
    • (2001) Int Immunol , vol.13 , pp. 1383-1390
    • Lawson, T.M.1    Man, S.2    Wang, E.C.Y.3    Williams, S.4    Amos, N.5    Gillespie, G.M.6
  • 19
    • 0035101408 scopus 로고    scopus 로고
    • Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients
    • Palermo B, Campanelli R, Mantovani S, Lantelme E, Manganoni AM, Carella G, et al.: Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients. Eur J Immunol 2001;31:412-420.
    • (2001) Eur J Immunol , vol.31 , pp. 412-420
    • Palermo, B.1    Campanelli, R.2    Mantovani, S.3    Lantelme, E.4    Manganoni, A.M.5    Carella, G.6
  • 20
    • 0035876928 scopus 로고    scopus 로고
    • Cutting edge: Lipid raft integrity affects the efficiency of MHC class I tetramer binding and cell surface TCR arrangement on CD8+ T cells
    • Drake DR, III, Braciale TJ: Cutting edge: lipid raft integrity affects the efficiency of MHC class I tetramer binding and cell surface TCR arrangement on CD8+ T cells. J Immunol 2001;166:7009-7013.
    • (2001) J Immunol , vol.166 , pp. 7009-7013
    • Drake III, D.R.1    Braciale, T.J.2
  • 21
    • 0035108309 scopus 로고    scopus 로고
    • Increased TCR avidity after T cell activation: A mechanism for sensing low-density antigen
    • Fahmy TM, Bieler JG, Edidin M, Schneck JP: Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen. Immunity 2001;14:135-143.
    • (2001) Immunity , vol.14 , pp. 135-143
    • Fahmy, T.M.1    Bieler, J.G.2    Edidin, M.3    Schneck, J.P.4
  • 22
    • 0036786444 scopus 로고    scopus 로고
    • Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity
    • Cawthon AG, Alexander-Miller MA: Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity. J Immunol 2002;169: 3492-3498.
    • (2002) J Immunol , vol.169 , pp. 3492-3498
    • Cawthon, A.G.1    Alexander-Miller, M.A.2
  • 23
    • 0037307095 scopus 로고    scopus 로고
    • The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation
    • Zamoyska R, Basson A, Filby A, Legname G, Lovatt M, Seddon B: The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation. Immunol Rev 2003;191:107-118.
    • (2003) Immunol Rev , vol.191 , pp. 107-118
    • Zamoyska, R.1    Basson, A.2    Filby, A.3    Legname, G.4    Lovatt, M.5    Seddon, B.6
  • 24
    • 0042971650 scopus 로고    scopus 로고
    • Molecular interactions mediating T cell antigen recognition
    • van der Merwe PA, Davis SJ: Molecular interactions mediating T cell antigen recognition. Annu Rev Immunol 2003;21:659-684.
    • (2003) Annu Rev Immunol , vol.21 , pp. 659-684
    • Van Der Merwe, P.A.1    Davis, S.J.2
  • 25
    • 0033613826 scopus 로고    scopus 로고
    • T lymphocyte costimulation mediated by reorganization of membrane microdomains
    • Viola A, Schroeder S, Sakakibara Y, Lanzavecchia A: T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 1999;283:680-682.
    • (1999) Science , vol.283 , pp. 680-682
    • Viola, A.1    Schroeder, S.2    Sakakibara, Y.3    Lanzavecchia, A.4
  • 28
    • 0036884294 scopus 로고    scopus 로고
    • Live-cell dynamics and the role of costimulation in immunological synapse formation
    • Wetzel SA, McKeithan TW, Parker DC: Live-cell dynamics and the role of costimulation in immunological synapse formation. J Immunol 2002;169:6092-6101.
    • (2002) J Immunol , vol.169 , pp. 6092-6101
    • Wetzel, S.A.1    McKeithan, T.W.2    Parker, D.C.3
  • 30
    • 0037218347 scopus 로고    scopus 로고
    • + T cells are the initial population elicited following viral infection of the respiratory tract
    • + T cells are the initial population elicited following viral infection of the respiratory tract. J Immunol 2003;170:174-181.
    • (2003) J Immunol , vol.170 , pp. 174-181
    • Gray, P.M.1    Parks, G.D.2    Alexander-Miller, M.A.3
  • 31
    • 0034790863 scopus 로고    scopus 로고
    • A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5
    • Gray PM, Parks GD, Alexander-Miller MA: A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5. J Virol 2001;75:10065-10072.
    • (2001) J Virol , vol.75 , pp. 10065-10072
    • Gray, P.M.1    Parks, G.D.2    Alexander-Miller, M.A.3
  • 32
    • 0034889233 scopus 로고    scopus 로고
    • + T cells without selection of higher affinity TCR
    • + T cells without selection of higher affinity TCR. Nat Immunol 2001;2:711-717.
    • (2001) Nat Immunol , vol.2 , pp. 711-717
    • Slifka, M.K.1    Whitton, J.L.2
  • 33
    • 0029813121 scopus 로고    scopus 로고
    • Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL
    • Alexander-Miller MA, Leggatt GR, Sarin A, Berzofsky JA: Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. J Exp Med 1996;184:485-492.
    • (1996) J Exp Med , vol.184 , pp. 485-492
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Sarin, A.3    Berzofsky, J.A.4
  • 34
    • 0034651651 scopus 로고    scopus 로고
    • MHC polymorphism can enrich the T cell repertoire of the species by shifts in intrathymic selection
    • Dyall R, Messaoudi I, Janetzki S, Nikolic-Zugic J: MHC polymorphism can enrich the T cell repertoire of the species by shifts in intrathymic selection. J Immunol 2000;164:1695-1698.
    • (2000) J Immunol , vol.164 , pp. 1695-1698
    • Dyall, R.1    Messaoudi, I.2    Janetzki, S.3    Nikolic-Zugic, J.4
  • 35
    • 0033214423 scopus 로고    scopus 로고
    • The induction of virus-specific CTL as a function of increasing epitope expression: Responses rise steadily until excessively high levels of epitope are attained
    • Wherry EJ, Puorro KA, Porgador A, Eisenlohr LC: The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. J Immunol 1999;163:3735-3745.
    • (1999) J Immunol , vol.163 , pp. 3735-3745
    • Wherry, E.J.1    Puorro, K.A.2    Porgador, A.3    Eisenlohr, L.C.4
  • 36
    • 0036569213 scopus 로고    scopus 로고
    • + T cell memory in response to low, high, and excessive levels of epitope
    • + T cell memory in response to low, high, and excessive levels of epitope. J Immunol 2002;168:4455-4461.
    • (2002) J Immunol , vol.168 , pp. 4455-4461
    • Wherry, E.J.1    McElhaugh, M.J.2    Eisenlohr, L.C.3
  • 39
    • 0345535130 scopus 로고    scopus 로고
    • Selective induction of high-avidity CTL by altering the balance of signals from APC
    • Oh S, Hodge JW, Ahlers JD, Burke DS, Schlom J, Berzofsky JA: Selective induction of high-avidity CTL by altering the balance of signals from APC. J Immunol 2003;170:2523-2530.
    • (2003) J Immunol , vol.170 , pp. 2523-2530
    • Oh, S.1    Hodge, J.W.2    Ahlers, J.D.3    Burke, D.S.4    Schlom, J.5    Berzofsky, J.A.6
  • 40
    • 0027158798 scopus 로고
    • Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
    • Moskophidis D, Lechner F, Pircher H, Zinkernagel RM: Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993;362:758-761.
    • (1993) Nature , vol.362 , pp. 758-761
    • Moskophidis, D.1    Lechner, F.2    Pircher, H.3    Zinkernagel, R.M.4
  • 41
    • 0032482176 scopus 로고    scopus 로고
    • Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
    • Gallimore A, Glithero A, Godkin A, Tissot AC, Pluckthun A, Elliott T, et al.: Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J Exp Med 1998;187:1383-1393.
    • (1998) J Exp Med , vol.187 , pp. 1383-1393
    • Gallimore, A.1    Glithero, A.2    Godkin, A.3    Tissot, A.C.4    Pluckthun, A.5    Elliott, T.6
  • 43
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, Dohrenwend P, et al.: Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 2000;191:1499-1512.
    • (2000) J Exp Med , vol.191 , pp. 1499-1512
    • Lechner, F.1    Wong, D.K.2    Dunbar, P.R.3    Chapman, R.4    Chung, R.T.5    Dohrenwend, P.6
  • 46
    • 0035809316 scopus 로고    scopus 로고
    • Assessing CD8 T cell number and dysfunction in the presence of antigen
    • Welsh RM: Assessing CD8 T cell number and dysfunction in the presence of antigen. J Exp Med 2001;193: 19F-22.
    • (2001) J Exp Med , vol.193
    • Welsh, R.M.1
  • 48
    • 0032547813 scopus 로고    scopus 로고
    • Supraoptimal peptide-major histocompatibility complex causes a decrease in bcl-2 levels and allows tumor necrosis factor alpha receptor II- mediated apoptosis of cytotoxic T lymphocytes
    • Alexander-Miller MA, Derby MA, Sarin A, Henkart PA, Berzofsky JA: Supraoptimal peptide-major histocompatibility complex causes a decrease in bcl-2 levels and allows tumor necrosis factor alpha receptor II- mediated apoptosis of cytotoxic T lymphocytes. J Exp Med 1998;188:1391-1399.
    • (1998) J Exp Med , vol.188 , pp. 1391-1399
    • Alexander-Miller, M.A.1    Derby, M.A.2    Sarin, A.3    Henkart, P.A.4    Berzofsky, J.A.5


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