MHC polymorphism can enrich the T cell repertoire of the species by shifts in intrathymic selection

Journal of Immunology

Volumn 164, Issue 4, 2000, Pages 1695-1698

  Dyall, Ruben ^a   Messaoudi, Ilhem ^a,b   Janetzki, Sylvia ^a   Nikolić Žugić, Janko ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENETIC POLYMORPHISM; GENETIC SELECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; T LYMPHOCYTE; THYMUS;

EID: 0034651651     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.4.1695     Document Type: Article

References (29)

1. Germain, R. N., and D. H. Margulies. 1993. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:403.
2. Fink, P. J., and M. J. Bevan. 1995. Positive selection of thymocytes. Adv. Immunol. 59:99.
3. Nossal, G. V. J. 1994. Negative selection of lymphocytes. Cell 76:229.
4. Lawlor, D. A., J. Zemmour, P. D. Ennis, and P. Parham. 1990. Evolution of class I-MHC genes and proteins. Annu. Rev. Immunol. 8:23.
5. Egorov, I. K. 1967. A mutation of histocompatibility-2 locus in the mouse. Genetika 3:136.
6. Parham, P., E. J. Adams, and K. L. Arnett. 1995. The origins of HLA-A, B, C polymorphism. Immunol. Rev. 143:141.
7. McDevitt, H. 1995. Evolution of MHC class II allelic diversity. Immunol. Rev. 143:113.
8. Bjorkman, P. J., M. A. Saper, B. Samraoui, W. S. Bennett, I. L. Strominger, and D. C. Wiley. 1987. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 329:512.
9. b. Science 257:919.
10. 1 mice: a comparison between thymic selection and antigen presentation. Int. Immunol. 1:1.
11. Racioppi, L., F. Ronchese, R. H. Schwartz, and R. N. Germain. 1991. The molecular basis of class II MHC allelic control of T cell responses. J. Immunol. 147:3718.
12. Heber-Katz, E., D. Hansburg, and R. H. Schwartz. 1983. The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation. J. Mol. Cell. Immunol. 1:3.
13. Gilfillan, S., S. Aiso, D. Smilek, D. L. Woodland, E. Palmer, and H. O. McDevitt. 1991. An immune defect due to low levels of class II cell surface expression: analysis of antigen presentation and positive selection. J. Immunol. 147:4074.
14. Schwartz, R. H. 1987. Immune response (Ir) genes of the murine major histocompatibility complex. Adv. Immunol. 38:31.
15. Takahata, N. 1995. MHC diversity and selection. Immunol. Rev. 143:225.
16. Ogasawara, K., W. L. Maloy, and R. H. Schwartz. 1987. Failure to find holes in the T cell repertoire. Nature 325:450.
17. Nathenson, S. G., J. Geliebter, G. M. Pfaffenbach, and R. A. Zeff. 1986. Murine major histocompatibility complex class I mutants. Annu. Rev. Immunol. 4:471.
18. Dyall, R., L. V. Vasović, A. Molano, and J. Nikolić-Žugić. 1995. CD4-independent in vivo priming of murine CTLs by optimal MHC class I-restricted peptides derived from HIV and other pathogens. Int. Immunol. 7:1205.
19. Dyall, R., D. H. Fremont, S. C. Jameson, and J. Nikolić-Žugić. 1996. T cell receptor (TCR) recognition of MHC class I variants: intermolecular second-site reversion of an MHC mutation by substituted peptides provides evidence for peptide/MHC conformational variation. J. Exp. Med. 184:253.
20. Nikolić-Žugić, J., and M. J. Bevan. 1990. Role of self-peptides in positively selecting the T-cell repertoire. Nature 344:65.
21. Moore, M. W., F. R. Carbone, and M. J. Bevan. 1988. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54:777.
22. b-restricted ovalbumin determinant. Eur. J. Immunol. 20:2431.
23. Fremont, D. H., E. A. Stura, M. Matsumura, P. A. Peterson, and I. A. Wilson. 1995. Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. Proc. Natl. Acad. Sci. USA 92:2479.
24. b molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc. Natl. Acad. Sci. USA 89:8403.
25. b antigen recognition site. J. Immunol. 146:2145.
26. Rohren, E. M., L. R. Pease, H. L. Ploegh, and T. N. M. Schumacher. 1993. Polymorphisms in pockets of major histocompatibility complex class I molecules influence peptide preference. J. Exp. Med. 177:1713.
27. Cose, S. C., J. M. Kelly, and F. R. Carbone. 1995. Characterization of a diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential Vβ bias. J. Virol. 69:5849.
28. Kappler, J. W., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell 49:273.
29. Ron, Y., D. Lo, and J. Sprent. 1986. T cell specifity in twice-irradiated F parent bone marrow chimeras: failure to detect a role for immigrant marrow-derived cells in imprinting intrathymic H-2 restriction. J. Immunol. 137:1764.