Rac1 Activity is Required for the Activation of Hypoxia-inducible Factor 1

Journal of Biological Chemistry

Volumn 276, Issue 24, 2001, Pages 21166-21172

  Hirota, Kiichi ^a,b   Semenza, Gregg L ^b  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; PROTEINS;

HYPOXIA; SIGNAL TRANSDUCTION;

BIOCHEMISTRY;

GUANOSINE TRIPHOSPHATASE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; RAC1 PROTEIN; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; ENZYME INHIBITOR; FLAVONOID; GENISTEIN; HIF1A PROTEIN, HUMAN; HYBRID PROTEIN; IMIDAZOLE DERIVATIVE; MORPHOLINE DERIVATIVE; NUCLEAR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PYRIDINE DERIVATIVE; TRANSCRIPTION FACTOR;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROPOIESIS; GLYCOLYSIS; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; BINDING SITE; CELL CULTURE; CELL HYPOXIA; CELL LINE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC TRANSCRIPTION; GENETICS; MAMMAL; METABOLISM; PHYSIOLOGY; TRANSACTIVATION;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BINDING SITES; CELL HYPOXIA; CELL LINE; CHROMONES; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GENISTEIN; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMIDAZOLES; MAMMALS; MORPHOLINES; NUCLEAR PROTEINS; PYRIDINES; RAC1 GTP-BINDING PROTEIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0035877728     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100677200     Document Type: Article

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