Epicardial but not endocardial premature stimulation initiates ventricular tachyarrhythmia in canine in vitro model of long QT syndrome

Heart Rhythm

Volumn 1, Issue 6, 2004, Pages 684-694

  Ueda, Norihiro ^a   Zipes, Douglas P ^a   Wu, Jiashin ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Canine; Dispersion, Stimulation; Heterogeneity; In vitro; Long QT syndrome, Repolarization; Optical mapping; Ventricular tachycardia

Indexed keywords

SEA ANEMONE TOXIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG DISEASE; ENDOCARDIUM; EPICARDIUM; HEART MUSCLE CONDUCTION SYSTEM; HEART MUSCLE POTENTIAL; HEART MUSCLE REFRACTORY PERIOD; HEART PREEXCITATION; HEART REPOLARIZATION; HEART VENTRICLE TACHYCARDIA; HEART VENTRICLE WALL; HYPOTHESIS; IN VITRO STUDY; LONG QT SYNDROME; NONHUMAN; PRIORITY JOURNAL; TORSADE DES POINTES;

ACTION POTENTIALS; ANIMALS; CARDIOTONIC AGENTS; CNIDARIAN VENOMS; DOGS; ELECTRIC STIMULATION; ENDOCARDIUM; LONG QT SYNDROME; MODELS, ANIMAL; PERFUSION; PERICARDIUM; TACHYCARDIA, VENTRICULAR;

EID: 11144249994     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2004.07.019     Document Type: Article

References (36)

1. D.M. Roden R. Lazzara M.R. Rosen P.J. Schwartz J. Towbin G.M. Vincent Multiple mechanisms in the long-Q-T syndrome current knowledge, gaps, and future directions Circulation 94 1996 1996-2012
2. B. Surawicz Electrophysiologic substrate of torsade de pointes dispersion of repolarization or early afterdepolarization? J Am Coll Cardiol 14 1989 172-184
3. P.G. Volders M.A. Vos B. Szabo K.R. Sipido S.H.M. de Groot A.P.M. Gorgels H.J.J. Wellens R. Lazzara Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes time to revise current concepts Cardiovasc Res 46 2000 376-392
4. C.T. January J.M. Riddle Early afterdepolarizations mechanism of induction and block Circ Res 64 1989 977-990
5. C. Antzelevitch W. Shimizu G.-X. Yan S. Sicouri J. Weissenburger V.V. Nesterenko A. Burashnikov J. Di Diego J. Saffitz G.P. Thomas The M cell its contribution to the ECG and to normal and abnormal electrical function of the heart J Cardiovasc Electrophysiol 10 1999 1124-1152
6. M. Restivo E.B. Caref D.O. Kozhevnikov N. el-Sherif Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome J Cardiovasc Electrophysiol 15 2004 323-331
7. N. El-Sherif E.B. Caref H. Yin M. Restivo The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome Tridimensional mapping of activation and recovery patterns Circ Res 79 1996 474-492
8. J. Wu J. Wu D.P. Zipes Early afterdepolarizations, U waves, and torsade de pointes Circulation 105 2002 675-676
9. W. Shimizu C. Antzelevitch Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome Circulation 98 1998 2314-2322
10. W. Shimizu C. Antzelevitch Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de points in LQT2 and LQT3 models of the long-QT syndrome Circulation 96 1997 2038-2047
11. G.X. Yan C. Antzelevitch Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome Circulation 98 1998 1928-1936
12. J.M. Di Diego L. Belardinelli C. Antzelevitch Cisapride-induced transmural dispersion of repolarization and torsades de pointes in the canine left ventricular wedge preparation during epicardial stimulation Circulation 108 2003 1027-1033
13. F.G. Akar D.S. Rosenbaum Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure Circ Res 93 2003 638-645
14. + channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome Circulation 102 2000 706-712
15. J. Wu M. Biermann M. Rubart D.P. Zipes Cytochalasin D as excitation-contraction uncoupler for optically mapping action potentials in wedges of ventricular myocardium J Cardiovasc Electrophysiol 9 1998 1336-1347
16. J. Wu D.P. Zipes Transmural reentry during global acute ischemia and reperfusion in canine ventricular muscle Am J Physiol Heart Circ Physiol 280 2001 H2717-H2725
17. J. Wu D.P. Zipes Transmural reentry triggered by epicardial stimulation during acute ischemia in canine ventricular muscle Am J Physiol Heart Circ Physiol 283 2002 H2004-H2011
18. N. Ueda D.P. Zipes J. Wu Prior ischemia enhances arrhythmogenicity in isolated canine ventricular wedge model of long QT 3 Cardiovasc Res 63 2004 69-76
19. M. Biermann M. Rubart A. Moreno J. Wu A. Josiah-Durant D.P. Zipes Differential effects of cytochalasin D and 2,3 butanedione monoxime on isometric twitch force and transmembrane action potential in isolated ventricular muscle J Cardiovasc Electrophysiol 9 1998 1348-1357
20. J. Jalife G.E. Morley N.Y. Tallini D. Vaidya A fungal metabolite that eliminates motion artifacts J Cardiovasc Electrophysiol 9 1998 1358-1362
21. E.P. Anyukhovsky E.A. Sosunov M.R. Rosen Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium. In vitro and in vivo correlations Circulation 94 1996 1981-1988
22. J. Merot F. Charpentier J.M. Poirier G. Coutris J. Weissenburger Effects of chronic treatment by amiodarone on transmural heterogeneity of canine ventricular repolarization in vivo interactions with acute sotalol Cardiovasc Res 44 1999 303-314
23. C.R. Studenik Z. Zhou C.T. January Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome Br J Pharmacol 132 2001 85-92
24. W. Shimizu C. Antzelevitch Cellular and ionic basis for T-wave alternans under long-QT conditions Circulation 99 1999 1499-1507
25. M.N. Obreztchikova E.A. Sosunov E.P. Anyukhovsky N.S. Moise R.B. Robinson M.R. Rosen Heterogeneous ventricular repolarization provides a substrate for arrhythmias in a German shepherd model of spontaneous arrhythmic death Circulation 108 2003 1389-1394
26. K.R. Laurita S.D. Girouard D.S. Rosenbaum Modulation of ventricular repolarization by a premature stimulus Circ Res 79 1996 493-503
27. J.M. Fish J.M. Di Diego V. Nesterenko C. Antzelevitch Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization implications for biventricular pacing Circulation 109 2004 2136-2142
28. V.A. Medina-Ravell R.S. Lankipalli G.-X. Yan C. Antzelevitch N.A. Medina-Malpica O.A. Medina-Malpica C. Droogan P.R. Kowey Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization Circulation 107 2003 740-746
29. F.G. Akar G.-X. Yan C. Antzelevitch D.S. Rosenbaum Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome Circulation 105 2002 1247-1253
30. G.X. Yan Y. Wu T. Liu J. Wang R.A. Marinchak P.R. Kowey Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome direct evidence from intracellular recordings in the intact left ventricular wall Circulation 103 2001 2851-2856
31. G.X. Yan A. Joshi D. Guo T. Hlaing J. Martin X. Xu P.R. Kowey Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia Circulation 2004 (in press).
32. G.X. Yan C. Antzelevitch Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation Circulation 100 1999 1660-1666
33. Ks in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations J Cardiovasc Electrophysiol 13 2002 172-177
34. R.A. Bouchard R.B. Clark W.R. Giles Effects of action potential duration on excitation-contraction coupling in rat ventricular myocytes Circ Res 76 1995 790-801
35. Z. Ming R. Aronson C. Nordin Mechanism of current-induced early afterdepolarizations in guinea pig ventricular myocytes Am J Physiol Heart Circ Physiol 267 1994 H1419-H428
36. G.X. Yan S.J. Rials Y. Wu T. Liu X. Xu R.A. Marinchak P.R. Kowey Ventricular hypertrophy amplifies transmural repolarization dispersion and induces early afterdepolarization Am J Physiol Heart Circ Physiol 281 2001 H1968-H1975