Dissecting Structural and Electrostatic Interactions of Charged Groups in α-Sarcin. An NMR Study of Some Mutants Involving the Catalytic Residues

Biochemistry

Volumn 42, Issue 45, 2003, Pages 13122-13133

  García Mayoral, Ma Flor ^a   Pérez Cañadillas, José Manuel ^a,d   Santoro, Jorge ^a   Ibarra Molero, Beatriz ^b   Sanchez Ruiz, José Manuel ^b   Lacadena, Javier ^c   Martínez Del Pozo, Álvaro ^c   Gavilanes, José G ^c   Rico, Manuel ^a   Bruix, Marta ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CHEMICAL BONDS; ELECTROSTATICS; GENETIC ENGINEERING; MATHEMATICAL MODELS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH EFFECTS;

RIBOTOXINS;

ENZYMES;

ALPHA SARCIN; RIBONUCLEASE;

ARTICLE; CATALYSIS; CYTOTOXICITY; DIELECTRIC CONSTANT; ELECTRICITY; ENZYME ACTIVE SITE; ENZYME STABILITY; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ASPERGILLUS; BINDING SITES; CATALYTIC DOMAIN; ELECTROSTATICS; ENDORIBONUCLEASES; FUNGAL PROTEINS; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTONS;

EID: 10744228944     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0349773     Document Type: Article

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