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Volumn 35, Issue 2, 2004, Pages 246-253

Expression of Constitutively Active Nuclear-κB RelA Transcription Factor in Blasts of Acute Myeloid Leukemia

Author keywords

Bone marrow; Leukemia; Myelodysplastic syndrome; NF B

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; TRANSCRIPTION FACTOR RELA;

EID: 10744224210     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2003.08.020     Document Type: Article
Times cited : (68)

References (35)
  • 2
    • 0029984863 scopus 로고    scopus 로고
    • The control of hematopoiesis and leukemia: From basic biology to the clinic
    • Sachs L: The control of hematopoiesis and leukemia: From basic biology to the clinic. Proc Natl Acad Sci USA 93:4742-4749, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4742-4749
    • Sachs, L.1
  • 3
    • 0037315894 scopus 로고    scopus 로고
    • Disruption of differentiation in human cancer: AML shows the way
    • Tenen DG: Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 3:89-101, 2003
    • (2003) Nat Rev Cancer , vol.3 , pp. 89-101
    • Tenen, D.G.1
  • 4
    • 0032900439 scopus 로고    scopus 로고
    • New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases
    • Chen F, Castranova V, Shi X, et al: New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem 45:7-17, 1999
    • (1999) Clin Chem , vol.45 , pp. 7-17
    • Chen, F.1    Castranova, V.2    Shi, X.3
  • 5
    • 0031126554 scopus 로고    scopus 로고
    • Rel/NF-κB transcription factors and the control of apoptosis
    • Sonenshein GE: Rel/NF-κB transcription factors and the control of apoptosis. Semin Cancer Biol 8:113-119, 1997
    • (1997) Semin Cancer Biol , vol.8 , pp. 113-119
    • Sonenshein, G.E.1
  • 6
    • 0029662342 scopus 로고    scopus 로고
    • Rel/NF-κB/IκB proteins and cancer
    • Gilmore TD, Koedood M, Piffat KA, et al: Rel/NF-κB/IκB proteins and cancer. Oncogene 14:1367-1378, 1997
    • (1997) Oncogene , vol.14 , pp. 1367-1378
    • Gilmore, T.D.1    Koedood, M.2    Piffat, K.A.3
  • 7
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
    • Baldwin AS: Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 107:241-246, 2001
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 8
    • 85047699198 scopus 로고    scopus 로고
    • Nuclear transcription factor-κB as a target for cancer development
    • Garg A, Aggarwal BB: Nuclear transcription factor-κB as a target for cancer development. Leukemia 16:1053-1068, 2002
    • (2002) Leukemia , vol.16 , pp. 1053-1068
    • Garg, A.1    Aggarwal, B.B.2
  • 9
    • 0033562798 scopus 로고    scopus 로고
    • An essential role for NF-κB in human CD34+ bone marrow cell survival
    • Pyatt DW, Stillman WS, Yang Y, et al: An essential role for NF-κB in human CD34+ bone marrow cell survival. Blood 93;3302-3308, 1999
    • (1999) Blood , vol.93 , pp. 3302-3308
    • Pyatt, D.W.1    Stillman, W.S.2    Yang, Y.3
  • 10
    • 0037203538 scopus 로고    scopus 로고
    • Nuclear factor kB activation: A question of life or death
    • Shishodia S, Aggarwal BB: Nuclear factor kB activation: A question of life or death. J Biochem Mol Biol 35:28-40, 2002
    • (2002) J Biochem Mol Biol , vol.35 , pp. 28-40
    • Shishodia, S.1    Aggarwal, B.B.2
  • 11
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin M, Ben-Neriah Y: Phosphorylation meets ubiquitination: The control of NF-κB activity. Ann Rev Immunol 18:621-663, 2000
    • (2000) Ann Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 12
    • 0032081311 scopus 로고    scopus 로고
    • NF-κB transcription factors are involved in normal erythropoiesis
    • Zhang M-Y, Sun S-C, Bell L, et al: NF-κB transcription factors are involved in normal erythropoiesis. Blood 91:4136-4144, 1998
    • (1998) Blood , vol.91 , pp. 4136-4144
    • Zhang, M.-Y.1    Sun, S.-C.2    Bell, L.3
  • 13
    • 0030610685 scopus 로고    scopus 로고
    • Activation of the NF-κB pathway by inflammatory stimuli in human neutrophils
    • McDonald PP, Bald A, Cassatella MA: Activation of the NF-κB pathway by inflammatory stimuli in human neutrophils. Blood 89:3421-3433, 1997
    • (1997) Blood , vol.89 , pp. 3421-3433
    • McDonald, P.P.1    Bald, A.2    Cassatella, M.A.3
  • 14
    • 0031833431 scopus 로고    scopus 로고
    • The regulation and roles of Rel/NF-κB transcription factors during lymphocyte activation
    • Gerondakis S, Grumont R, Rourke I, et al: The regulation and roles of Rel/NF-κB transcription factors during lymphocyte activation. Curr Opin Immunol 10:353-359, 1998
    • (1998) Curr Opin Immunol , vol.10 , pp. 353-359
    • Gerondakis, S.1    Grumont, R.2    Rourke, I.3
  • 15
    • 0032473405 scopus 로고    scopus 로고
    • B lymphocytes differentially use the Rel and nuclear factor kB1 (NF-κB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells
    • Grumont RJ, Rourke IJ, O'Reilly LA, et al: B lymphocytes differentially use the Rel and nuclear factor kB1 (NF-κB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J Exp Med 187:663-674, 1998
    • (1998) J Exp Med , vol.187 , pp. 663-674
    • Grumont, R.J.1    Rourke, I.J.2    O'Reilly, L.A.3
  • 16
    • 0031975585 scopus 로고    scopus 로고
    • Regulation of immune responses by NF-κB/Rel transcription factors
    • Sha WC: Regulation of immune responses by NF-κB/Rel transcription factors. J Exp Med 187:143-146, 1998
    • (1998) J Exp Med , vol.187 , pp. 143-146
    • Sha, W.C.1
  • 17
    • 0025823675 scopus 로고
    • Alterations at the rel locus in human lymphoma
    • Lu D, Thompson JD, Gorski GK, et al: Alterations at the rel locus in human lymphoma. Oncogene 6:1235-1241, 1991
    • (1991) Oncogene , vol.6 , pp. 1235-1241
    • Lu, D.1    Thompson, J.D.2    Gorski, G.K.3
  • 18
    • 0026331456 scopus 로고
    • B-cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50
    • Neri A, Chang C-C, Lombardi L, et al: B-cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50. Cell 67:1075-1087, 1991
    • (1991) Cell , vol.67 , pp. 1075-1087
    • Neri, A.1    Chang, C.-C.2    Lombardi, L.3
  • 19
    • 18844465632 scopus 로고    scopus 로고
    • Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
    • Bargou RC, Emmerich F, Krappmann D, et al: Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest 100:2961-2969, 1997
    • (1997) J Clin Invest , vol.100 , pp. 2961-2969
    • Bargou, R.C.1    Emmerich, F.2    Krappmann, D.3
  • 20
    • 0033230955 scopus 로고    scopus 로고
    • Overexpression of I kappa B alpha without inhibition of NF-κβ activity and mutations in the I kappa alpha gene in Reed-Sternberg cells
    • Emmerich F, Meiser M, Hummel M, et al: Overexpression of I kappa B alpha without inhibition of NF-κβ activity and mutations in the I kappa alpha gene in Reed-Sternberg cells. Blood 94:3129-3134, 1999
    • (1999) Blood , vol.94 , pp. 3129-3134
    • Emmerich, F.1    Meiser, M.2    Hummel, M.3
  • 21
    • 0028986985 scopus 로고
    • The spontaneous expression of interleukin-1β and interleukin-6 is associated with spontaneous expression of AP-1 and NF-κB transcription factor in acute myeloblastic leukemia cells
    • Dokter WHA, Tuyt L, Sierdsema SJ, et al: The spontaneous expression of interleukin-1β and interleukin-6 is associated with spontaneous expression of AP-1 and NF-κB transcription factor in acute myeloblastic leukemia cells. Leukemia 9:425-432, 1995
    • (1995) Leukemia , vol.9 , pp. 425-432
    • Dokter, W.H.A.1    Tuyt, L.2    Sierdsema, S.J.3
  • 22
    • 0034092559 scopus 로고    scopus 로고
    • Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells
    • Kordes U, Krappmann D, Heissmeyer V, et al: Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia 14:399-402, 2000
    • (2000) Leukemia , vol.14 , pp. 399-402
    • Kordes, U.1    Krappmann, D.2    Heissmeyer, V.3
  • 23
    • 0033120826 scopus 로고    scopus 로고
    • Constitutive activation of NF-κB in primary adult T-cell leukemia cells
    • Mori N, Fujii M, Ikeda S, et al: Constitutive activation of NF-κB in primary adult T-cell leukemia cells. Blood 93:2360-2368, 1999
    • (1999) Blood , vol.93 , pp. 2360-2368
    • Mori, N.1    Fujii, M.2    Ikeda, S.3
  • 24
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, Neering SJ, Upchurch D, et al: Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 98:2301-2307, 2001
    • (2001) Blood , vol.98 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3
  • 25
    • 0037059012 scopus 로고    scopus 로고
    • Preferential induction of apoptosis for primary human leukemic stem cells
    • Guzman ML, Swiderski CF, Howard DS, et al: Preferential induction of apoptosis for primary human leukemic stem cells. Proc Natl Acad Sci USA 99:16220-16225, 2002
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16220-16225
    • Guzman, M.L.1    Swiderski, C.F.2    Howard, D.S.3
  • 26
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 Trial
    • The Medical Research Council Adult and Children's Leukemia Working Parties
    • Grimwade D, Walker H, Oliver F, et al: The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 Trial. The Medical Research Council Adult and Children's Leukemia Working Parties. Blood 92: 2322-2333, 1998
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 28
    • 0030773543 scopus 로고    scopus 로고
    • Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBα phosphorylation, and degradation
    • Chaturvedi MM, Kumar A, Darnay BG, et al: Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBα phosphorylation, and degradation. J Biol Chem 272:30129-30134, 1997
    • (1997) J Biol Chem , vol.272 , pp. 30129-30134
    • Chaturvedi, M.M.1    Kumar, A.2    Darnay, B.G.3
  • 29
    • 0036892729 scopus 로고    scopus 로고
    • BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens
    • Rassidakis GZ, Medeiros LJ, Vassilakopoulos TP, et al: BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens. Blood 100:3935-3941, 2002
    • (2002) Blood , vol.100 , pp. 3935-3941
    • Rassidakis, G.Z.1    Medeiros, L.J.2    Vassilakopoulos, T.P.3
  • 30
    • 0028207530 scopus 로고
    • Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter
    • Dunn SM, Coles LS, Lang RK, et al: Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter. Blood 83:2469-2479, 1994
    • (1994) Blood , vol.83 , pp. 2469-2479
    • Dunn, S.M.1    Coles, L.S.2    Lang, R.K.3
  • 31
    • 0032848438 scopus 로고    scopus 로고
    • Apoptosis in patients with myelodysplastic syndromes: Differential involvement of marrow cells in "good" versus "poor" prognosis patients and correlation with apoptosis-related genes
    • Tsoplou P, Kouraklis-Symeonidis A, Thanopoulou E, et al: Apoptosis in patients with myelodysplastic syndromes: Differential involvement of marrow cells in "good" versus "poor" prognosis patients and correlation with apoptosis-related genes. Leukemia 13: 1554-1563, 1999
    • (1999) Leukemia , vol.13 , pp. 1554-1563
    • Tsoplou, P.1    Kouraklis-Symeonidis, A.2    Thanopoulou, E.3
  • 32
    • 0031741577 scopus 로고    scopus 로고
    • Molecular pathophysiology of chronic myelogenous leukemia
    • Turhan AG, Solary E, Vaichenker W, et al: Molecular pathophysiology of chronic myelogenous leukemia. Hematol Cell Ther 40:217-221, 1998
    • (1998) Hematol Cell Ther , vol.40 , pp. 217-221
    • Turhan, A.G.1    Solary, E.2    Vaichenker, W.3
  • 33
    • 0032034216 scopus 로고    scopus 로고
    • A requirement for NF-κB activation in Bcr-Abl-mediated transformation
    • Reuther JY, Reuther GW, Cortez D, et al: A requirement for NF-κB activation in Bcr-Abl-mediated transformation. Genes Dev 12: 968-981, 1998
    • (1998) Genes Dev , vol.12 , pp. 968-981
    • Reuther, J.Y.1    Reuther, G.W.2    Cortez, D.3
  • 34
    • 0036566242 scopus 로고    scopus 로고
    • Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
    • Milella M, Estrov Z, Kornblau SM, et al: Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia. Blood 99:3461-3464, 2002
    • (2002) Blood , vol.99 , pp. 3461-3464
    • Milella, M.1    Estrov, Z.2    Kornblau, S.M.3
  • 35
    • 0032878542 scopus 로고    scopus 로고
    • Phenylarsine oxide blocks interleukin-1κ-induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells
    • Estrov Z, Manna SK, Harris D, et al: Phenylarsine oxide blocks interleukin-1κ-induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells. Blood 94:2844-2853, 1999
    • (1999) Blood , vol.94 , pp. 2844-2853
    • Estrov, Z.1    Manna, S.K.2    Harris, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.