-
1
-
-
0028147448
-
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway
-
Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T (1994) : Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway, EMBO J 13:764-773
-
(1994)
EMBO J
, vol.13
, pp. 764-773
-
-
Puil, L.1
Liu, J.2
Gish, G.3
Mbamalu, G.4
Bowtell, D.5
Pelicci, P.G.6
Arlinghaus, R.7
Pawson, T.8
-
2
-
-
0029087475
-
Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene
-
Goga A, McLaughlin J, Afar DE, Saffran DC, Witte ON (1995) : Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene. Cell 82:981-988
-
(1995)
Cell
, vol.82
, pp. 981-988
-
-
Goga, A.1
McLaughlin, J.2
Afar, D.E.3
Saffran, D.C.4
Witte, O.N.5
-
3
-
-
0028895008
-
Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation
-
Gishizky ML, Cortez D, Pendergast AM (1995): Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation. Proc Natl Acad Sci U S A 92:10889-10893
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 10889-10893
-
-
Gishizky, M.L.1
Cortez, D.2
Pendergast, A.M.3
-
4
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
Sawyers CL, Callahan W, Witte ON (1992): Dominant negative MYC blocks transformation by ABL oncogenes. Cell 70: 901-910
-
(1992)
Cell
, vol.70
, pp. 901-910
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
6
-
-
0029063970
-
Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells
-
Skorski T, Kanakaraj P, Nieborowska-Skorska M, Ratajczak MZ, Wen SC, Zon G, Gewirtz AM, Perussia B, Calabretta B (1995) : Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood 86 :726-736
-
(1995)
Blood
, vol.86
, pp. 726-736
-
-
Skorski, T.1
Kanakaraj, P.2
Nieborowska-Skorska, M.3
Ratajczak, M.Z.4
Wen, S.C.5
Zon, G.6
Gewirtz, A.M.7
Perussia, B.8
Calabretta, B.9
-
7
-
-
0030710188
-
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
-
Skorski T, Bellacosa A, Nieborowska-Skorska M, Majewski M, Martinez R, Choi JK, Trotta R, Wlodarski P,Perrotti D, Chan TO, Wasik MA, Tsichlis PN, Calabretta B (1997): Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J 16 :6151-6161
-
(1997)
EMBO J
, vol.16
, pp. 6151-6161
-
-
Skorski, T.1
Bellacosa, A.2
Nieborowska-Skorska, M.3
Majewski, M.4
Martinez, R.5
Choi, J.K.6
Trotta, R.7
Wlodarski, P.8
Perrotti, D.9
Chan, T.O.10
Wasik, M.A.11
Tsichlis, P.N.12
Calabretta, B.13
-
8
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME (1997) : Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91 :231-241
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
9
-
-
0032543578
-
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser 136
-
Blume-Jensen P, Janknecht R, Hunter T (1998): The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser 136. Curr Biol 8 :779-782
-
(1998)
Curr Biol
, vol.8
, pp. 779-782
-
-
Blume-Jensen, P.1
Janknecht, R.2
Hunter, T.3
-
10
-
-
0029863169
-
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
-
Carlesso N, Frank DA, Griffin JD (1996) : Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. J Exp Med 183:811-820
-
(1996)
J Exp Med
, vol.183
, pp. 811-820
-
-
Carlesso, N.1
Frank, D.A.2
Griffin, J.D.3
-
11
-
-
0000506439
-
P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
-
Ilaria RL Jr, Van Etten RA (1996): P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem 271:31704-31710
-
(1996)
J Biol Chem
, vol.271
, pp. 31704-31710
-
-
Ilaria Jr., R.L.1
Van Etten, R.A.2
-
12
-
-
15144349364
-
BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line
-
Ahmed M, Dusanter-Fourt I, Bernard M, Mayeux P, Hawley RG, Bennardo T, Novault S, Bonnet ML, Gisselbrecht S, Varet B, Turhan AG (1998): BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line. Oncogene 16: 489-496
-
(1998)
Oncogene
, vol.16
, pp. 489-496
-
-
Ahmed, M.1
Dusanter-Fourt, I.2
Bernard, M.3
Mayeux, P.4
Hawley, R.G.5
Bennardo, T.6
Novault, S.7
Bonnet, M.L.8
Gisselbrecht, S.9
Varet, B.10
Turhan, A.G.11
-
13
-
-
0031573141
-
Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients
-
Chai SK, Nichols GL, Rothman P (1997): Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients. J Immunol 159 :4720-4728
-
(1997)
J Immunol
, vol.159
, pp. 4720-4728
-
-
Chai, S.K.1
Nichols, G.L.2
Rothman, P.3
-
14
-
-
0028817880
-
Jak-STAT signaling induced by the v-abl oncogene
-
Danial NN, Pernis A, Rothman PB (1995): Jak-STAT signaling induced by the v-abl oncogene. Science 269 :1875-1877
-
(1995)
Science
, vol.269
, pp. 1875-1877
-
-
Danial, N.N.1
Pernis, A.2
Rothman, P.B.3
-
15
-
-
0029999656
-
Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis
-
Grimm S, Bauer MK, Baeuerle PA, Schulze-Osthoff K (1996): Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis. J Cell Biol 134 :13-23
-
(1996)
J Cell Biol
, vol.134
, pp. 13-23
-
-
Grimm, S.1
Bauer, M.K.2
Baeuerle, P.A.3
Schulze-Osthoff, K.4
-
16
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA, Baltimore D (1996): An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274 :782-784
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
17
-
-
0030725774
-
Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line (P210BCR-ABL activates p65 NF-kappaB)
-
Hamdane M, David-Cordonnier MH, D'Halluin JC (1997): Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line (P210BCR-ABL activates p65 NF-kappaB). Oncogene 15:2267-2275
-
(1997)
Oncogene
, vol.15
, pp. 2267-2275
-
-
Hamdane, M.1
David-Cordonnier, M.H.2
D'Halluin, J.C.3
-
18
-
-
0032034216
-
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation
-
Reuther JY, Reuther GW, Cortez D, Pendergast AM, Baldwin AS Jr (1998) A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation. Genes Dev12 :968-981
-
(1998)
Genes Dev
, vol.12
, pp. 968-981
-
-
Reuther, J.Y.1
Reuther, G.W.2
Cortez, D.3
Pendergast, A.M.4
Baldwin Jr., A.S.5
-
19
-
-
0028142490
-
Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia
-
Oda T, Heaney C, Hagopian JR, Okuda K, Griffin JD, Druker BJ (1994): Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia. J Biol Chem 269:22925-22928
-
(1994)
J Biol Chem
, vol.269
, pp. 22925-22928
-
-
Oda, T.1
Heaney, C.2
Hagopian, J.R.3
Okuda, K.4
Griffin, J.D.5
Druker, B.J.6
-
20
-
-
0028971466
-
CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells
-
Salgia R, Uemura N, Okuda K, Li JL, Pisick E, Sattler M, de Jong R, Druker B, Heisterkamp N, Chen LB, et al (1995) : CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells. J Biol Chem 270 :29145-29150
-
(1995)
J Biol Chem
, vol.270
, pp. 29145-29150
-
-
Salgia, R.1
Uemura, N.2
Okuda, K.3
Li, J.L.4
Pisick, E.5
Sattler, M.6
De Jong, R.7
Druker, B.8
Heisterkamp, N.9
Chen, L.B.10
-
21
-
-
0029683347
-
Activation of Src kinases p53/56lyn and p59hck by p210bcr/abl in myeloid cells
-
Danhauser-Riedl S, Warmuth M, Druker BJ, Emmerich B, Hallek M (1996): Activation of Src kinases p53/56lyn and p59hck by p210bcr/abl in myeloid cells. Cancer Res 56 :3589-3596
-
(1996)
Cancer Res
, vol.56
, pp. 3589-3596
-
-
Danhauser-Riedl, S.1
Warmuth, M.2
Druker, B.J.3
Emmerich, B.4
Hallek, M.5
-
22
-
-
0029669975
-
The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway
-
Sattler M, Salgia R, Okuda K, Uemura N, Durstin MA, Pisick E, Xu G, Li JL, Prasad KV, Griffin JD (1996): The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway. Oncogene 12 :839-846
-
(1996)
Oncogene
, vol.12
, pp. 839-846
-
-
Sattler, M.1
Salgia, R.2
Okuda, K.3
Uemura, N.4
Durstin, M.A.5
Pisick, E.6
Xu, G.7
Li, J.L.8
Prasad, K.V.9
Griffin, J.D.10
-
23
-
-
0031459864
-
p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
-
Carpino N, Wisniewski D, Strife A, Marshak D, Kobayashi R, Stillman B, Clarkson B: p62(dok) (1997): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 88:197-204
-
(1997)
Cell
, vol.88
, pp. 197-204
-
-
Carpino, N.1
Wisniewski, D.2
Strife, A.3
Marshak, D.4
Kobayashi, R.5
Stillman, B.6
Clarkson, B.7
-
24
-
-
2642671984
-
Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo
-
LaMontagne KR Jr, Flint AJ, Franza BR Jr, Pandergast AM, Tonks NK (1998): Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Mol Cell Biol 18:2965-2975
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2965-2975
-
-
LaMontagne Jr., K.R.1
Flint, A.J.2
Franza Jr., B.R.3
Pandergast, A.M.4
Tonks, N.K.5
-
25
-
-
0032523919
-
Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway
-
Dai Z, Quackenbush RC, Courtney KD, Grove M, Cortez D, Reuther GW, Pendergast AM (1998) : Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway. Genes Dev 12:1415-1424
-
(1998)
Genes Dev
, vol.12
, pp. 1415-1424
-
-
Dai, Z.1
Quackenbush, R.C.2
Courtney, K.D.3
Grove, M.4
Cortez, D.5
Reuther, G.W.6
Pendergast, A.M.7
-
26
-
-
0030804379
-
New understanding of the pathogenesis of CML: A prototype of early neoplasia
-
Clarkson BD, Strife A, Wisniewski D, Lambek C, Carpino N (1997): New understanding of the pathogenesis of CML: a prototype of early neoplasia. Leukemia 11:1404-1428
-
(1997)
Leukemia
, vol.11
, pp. 1404-1428
-
-
Clarkson, B.D.1
Strife, A.2
Wisniewski, D.3
Lambek, C.4
Carpino, N.5
-
27
-
-
0023270373
-
Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia
-
Gordon MY, Dowding CR, Riley GP, Goldman JM, Greaves MF (1987): Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 328 :342-344
-
(1987)
Nature
, vol.328
, pp. 342-344
-
-
Gordon, M.Y.1
Dowding, C.R.2
Riley, G.P.3
Goldman, J.M.4
Greaves, M.F.5
-
28
-
-
0026441040
-
Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV
-
Verfaillie CM, McCarthy JB, McGlave PB (1992): Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. Decreased adhesion to stroma and fibronectin but increased adhesion to the basement membrane components laminin and collagen type IV. J Clin Invest 90 :1232-1241
-
(1992)
J Clin Invest
, vol.90
, pp. 1232-1241
-
-
Verfaillie, C.M.1
McCarthy, J.B.2
McGlave, P.B.3
-
29
-
-
0028178976
-
Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function
-
Bhatia R, Wayner EA, McGlave PB, Verfaillie CM (1994): Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function. J Clin Invest 94:384-391
-
(1994)
J Clin Invest
, vol.94
, pp. 384-391
-
-
Bhatia, R.1
Wayner, E.A.2
McGlave, P.B.3
Verfaillie, C.M.4
-
30
-
-
0030038231
-
Bcr/Abl expression stimulates integrin function in hematopoietic cell lines
-
Bazzoni G, Carlesso N, Griffin JD, Hemler ME (1996): Bcr/Abl expression stimulates integrin function in hematopoietic cell lines. J Clin Invest 98 :521-528
-
(1996)
J Clin Invest
, vol.98
, pp. 521-528
-
-
Bazzoni, G.1
Carlesso, N.2
Griffin, J.D.3
Hemler, M.E.4
-
31
-
-
0028875460
-
Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL
-
Salgia R, Brunkhorst B, Pisick E, Li JL, Lo SH, Chen LB, Griffin JD (1995): Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. Oncogene 11:1149-1155
-
(1995)
Oncogene
, vol.11
, pp. 1149-1155
-
-
Salgia, R.1
Brunkhorst, B.2
Pisick, E.3
Li, J.L.4
Lo, S.H.5
Chen, L.B.6
Griffin, J.D.7
-
33
-
-
0028027712
-
Growth of erythroid colonies in chronic myelogenous leukemia is independent of erythropoietin only in the presence of steel factor
-
Issaad C, Vainchenker W (1994): Growth of erythroid colonies in chronic myelogenous leukemia is independent of erythropoietin only in the presence of steel factor. Blood 84 :3447-3456
-
(1994)
Blood
, vol.84
, pp. 3447-3456
-
-
Issaad, C.1
Vainchenker, W.2
-
34
-
-
0028179281
-
Biological consequences of p160v-abl protein tyrosine kinase activity in a primitive, multipotent haemopoietic cell line
-
Spooncer E, Fairbairn L, Cowling GJ, Dexter TM, Whetton AD, Owen-Lynch PJ (1994) Biological consequences of p160v-abl protein tyrosine kinase activity in a primitive, multipotent haemopoietic cell line. Leukemia 8:620-630
-
(1994)
Leukemia
, vol.8
, pp. 620-630
-
-
Spooncer, E.1
Fairbairn, L.2
Cowling, G.J.3
Dexter, T.M.4
Whetton, A.D.5
Owen-Lynch, P.J.6
-
35
-
-
0027979832
-
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
-
McGahon A, Bissonnette R, Schmitt M, Cotter KM, Green DR, Cotter TG (1994): BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 83: 1179-1187
-
(1994)
Blood
, vol.83
, pp. 1179-1187
-
-
McGahon, A.1
Bissonnette, R.2
Schmitt, M.3
Cotter, K.M.4
Green, D.R.5
Cotter, T.G.6
-
36
-
-
0028256425
-
Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia
-
Bedi A, Zehnbauer BA, Barber JP, Sharkis SJ, Jones RJ (1994) : Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 83:2038-2044
-
(1994)
Blood
, vol.83
, pp. 2038-2044
-
-
Bedi, A.1
Zehnbauer, B.A.2
Barber, J.P.3
Sharkis, S.J.4
Jones, R.J.5
-
37
-
-
0030945972
-
Apoptosis in chronic myelogenous leukemia: Studies of stage-specific differences
-
Gisslinger H, Kurzrock R, Wetzler M, Tucker S, Kantarjian H, Robertson B, Talpaz M (1997) : Apoptosis in chronic myelogenous leukemia: studies of stage-specific differences. Leuk Lymphoma 25:121-133
-
(1997)
Leuk Lymphoma
, vol.25
, pp. 121-133
-
-
Gisslinger, H.1
Kurzrock, R.2
Wetzler, M.3
Tucker, S.4
Kantarjian, H.5
Robertson, B.6
Talpaz, M.7
-
38
-
-
0030065141
-
BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells
-
Roger R, Issaad C, Pallardy M, Leglise MC, Turhan AG, Bertoglio J, Breard J (1996): BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells. Blood 87:1113-1122
-
(1996)
Blood
, vol.87
, pp. 1113-1122
-
-
Roger, R.1
Issaad, C.2
Pallardy, M.3
Leglise, M.C.4
Turhan, A.G.5
Bertoglio, J.6
Breard, J.7
-
39
-
-
0030471795
-
The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway
-
Cortez D, Stoica G, Pierce JH, Pendergast AM: (1996) The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway. Oncogene 13 :2589-2594
-
(1996)
Oncogene
, vol.13
, pp. 2589-2594
-
-
Cortez, D.1
Stoica, G.2
Pierce, J.H.3
Pendergast, A.M.4
-
40
-
-
0029015690
-
Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2
-
Sanchez-Garcia I, Grutz G (1995): Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2. Proc Natl Acad Sci U S A 92:5287-5291
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5287-5291
-
-
Sanchez-Garcia, I.1
Grutz, G.2
-
41
-
-
0032055535
-
BCR-ABL delays apoptosis upstream of procaspase-3 activation
-
Dubrez L, Eymin B, Sordet O, Droin N, Turhan AG, Solary E (1998): BCR-ABL delays apoptosis upstream of procaspase-3 activation. Blood 91:2415-2422
-
(1998)
Blood
, vol.91
, pp. 2415-2422
-
-
Dubrez, L.1
Eymin, B.2
Sordet, O.3
Droin, N.4
Turhan, A.G.5
Solary, E.6
|