Kupffer cells from Schistosoma mansoni-infected mice participate in the prompt type 2 differentiation of hepatic T cells in response to worm antigens

Journal of Immunology

Volumn 163, Issue 12, 1999, Pages 6702-6711

  Hayashi, Nobuki ^a,e   Matsui, Kiyoshi ^a   Tsutsui, Hiroko ^a,d   Osada, Yoshio ^c   Mohamed, Raafat T ^c   Nakano, Hiroki ^a   Kashiwamura, Shin Ichiro ^a   Hyodo, Yasuko ^a   Takeda, Kiyoshi ^b,d   Akira, Shizuo ^b,d   Hada, Toshikazu ^a   Higashino, Kazuya ^a   Kojima, Somei ^c   Nakanishi, Kenji ^a,d  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; KUPFFER CELL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; T LYMPHOCYTE; WORM;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, HELMINTH; CELL DIFFERENTIATION; CYTOKINES; FEMALE; INTERLEUKIN-4; KUPFFER CELLS; LIFE CYCLE STAGES; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; OVUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TH2 CELLS; TIME FACTORS;

EID: 0032741370     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Kaufmann, S. H. 1989. Immunity to bacteria. Curr. Opin. Immunol. 2:353.
2. Sundler, R. 1997. Lysosomal and cytosolic pH as regulators of exocytosis in mouse macrophages. Acta Physiol. Scand. 161:553.
3. MacMicking, J., Q. W. Xie, and C. Nathan. 1997. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:323.
4. Beutler, B., and A. Cerami. 1989. The biology of cachectin/TNF-α primary mediator of the host response. Annu. Rev. Immunol. 7:625.
5. Sprent, J., and M. Schaefer. 1989. Antigen-presenting cells for unprimed T cells. Immunol. Today 10:17.
6. Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
7. Okamura, H., H. Tsutsui, S. Kashiwamura, T. Yoshimoto, and K. Nakanishi. 1998. Interleukin-18 (IL-18): a novel cytokine that augments both innate and acquired immunity. Adv. Immunol. 70:281.
8. Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385.
9. Scott, P. 1993. IL-12: Initiation cytokine for cell-mediated immunity. Science 260:496.
10. O'Garra, A. 1998. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 8:275.
11. Magram, J., S. E. Connaughton, R. R. Warner, D. M. Carvajal, C.-Y. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D. A. Faherty, and M. K. Gately. 1996. IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses. Immunity 4:471.
12. + T cells but induces type 1 T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells. J. Immunol. 159:97.
13. Takeda, K., H. Tsutsui, T. Yoshimoto, O. Adachi, H. Okamura, K. Nakanishi, and S. Akira. 1998. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8:383.
14. + T cell subsets in the regulation of parasite immunity and disease. Immunol. Rev. 112:161.
15. Kojima, S. 1998. Schistosomes. In Topley and Wilson's Microbiology and Microbial Infections. L. Collier, A. Balows, and M. Sussma, ed. Arnold, London, p. 479.
16. Pearce, E. J., P. Caspar, J.-M., Grzych, F. A. Lewis, and A. Sher. 1991. Down-regulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 173:159.
17. Kullberg, M. C., J. A. Berzofsky, D. Lj. Jankovic, S. Barbieri, M. E. Williams, P. Perlmann, A Sher, and M. Troye-Blomberg. 1996. T cell-derived IL-3 induces the production of IL-4 by non-B, non-T cells to amplify the Th2-cytokine response to a non-parasite antigen in Schistosoma mansoni-infected mice. J. Immunol. 156:1482.
18. Falcone, F. H., C. A. Dahinden, B. F. Gibbs, T. Noll, U. Amon, H. Hebestreit, O. Abrahamsen, J. Klauche, M. Schlaak, and H. Haas. 1996. Human basophils release interleukin-4 after stimulation with Schistosoma mansoni egg antigen. Eur. J. Immunol. 26:1147.
19. Pearce, E. J., S. L. James, S. Hieny, D. E. Lnar, and A. Sher. 1988. Induction of protective immunity against Schistosoma mansoni by vaccination with schistosoma paramyosin (Sm97), a nonsurface parasite antigen. Proc. Natl. Acad. Sci. USA 85:5678.
20. Takeda, K., T. Tanaka, W. Shi, M. Matsumoto, M. Minami, S.-I. Kashiwamura, K. Nakanishi, N. Yoshida, T. Kishimoto, and S. Akira. 1996. Essential role of Stat6 in IL-4 signaling. Nature 380:627.
21. Akimoto, T., F. Numata, M. Tamura, Y. Takata, N. Higashida, T. Takashi, K. Takeda, and S. Akira. 1998. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT) 6-deficient mice. J. Exp. Med. 187:1537.
22. Hasday, J. D., E. M. Shah, and A. P. Lieberman. 1990. Macrophage tumor necrosis factor-α release is induced by contact with some tumors. J. Immunol. 145:371.
23. Rafi, A., M. Nagarkatti, and P. S. Nagarkatti. 1997. Hyaluronate-CD44 interactions can induce murine B-cell activation. Blood 89:2901.
24. Okamura, H., H. Tsutsui, T. Komatsu, M. Yutsudo, A. Hakura, T. Tanimoto, K. Torigoe, T. Okura, Y. Nukada, K. Hattori, et al. 1995. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378:88.
25. Tsutsui, H., K. Matsui, N. Kawada, Y. Hyodo, N. Hayashi, H. Okamura, K. Higashino, and K. Nakanishi. 1997. IL-18 accounts for both TNF-α-and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice. J. Immunol. 159:3961.
26. Yoshimoto, T., H. Okamura, Y. Tagawa, Y. Iwakura, and K. Nakanishi. 1997. Interleukin 18 together with interleukin 12 inhibits Ig production by induction of interferon-γ production from activated B cells. Proc. Natl. Acad. Sci. USA 94: 3948.
27. Hyodo, Y., K. Matsui, N. Hayashi, H. Tsutsui, S.-I. Kashiwamura, H. Yamauchi, K. Hiroishi, K. Takeda, Y. Tagawa, Y. Iwakura, et al. 1999. IL-18 up-regulates perforin-mediated NK activity without increasing perform messenger RNA expression by binding to constitutively expressed IL-18 receptor. J. Immunol. 162: 1662.
28. Sato, K., K. Ohtsuka, K. Hasegawa, S. Yamagiwa, H. Watanabe, H. Asakura, and T. Abo. 1995. Evidence for extrathymic generation of intermediate T cell receptor cells in the liver revealed in thymectomized, irradiated mice subjected to bone marrow transplantation. J. Exp. Med. 182:759.
29. pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179:1285.
30. Le Gros, G., S. X. Ben-Sasson, R. Seder, F. D. Finkelman, and W. E Paul. 1990. Generation of interleukin-4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172:921.
31. Chatelain, R., K. Carkila, and R. L. Coffman. 1992. IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. 148:1182.
32. Abehsira-Amar, O., M. Gibert, M. Joliy, J. Théze, and D. L. Jankovic. 1992. IL-4 plays a dominant role in the differential development of Th0 into Th1 ad Th2 cells. J. Immunol. 148:3820.
33. +T cells. J. Exp. Med. 185:461.
34. Fitch, F. W., M. D. Mckisic, D. W. Lancki, and T. F. Gajewski. 1993. Differential regulation of murine T lymphocyte subsets. Annu. Rev. Immunol. 11:29.
35. Urban, J. F., Jr., N. Noben-Trauth, D. D. Donaldson, K. B. Madden, S. C. Morris, M. Collins, and F. D. Finkelman. 1998. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8:255.
36. Chiaramonte, M. G., L.R. Schopf, T. Y. Neben, A. W. Cheever, D. D. Donaldson, and T. A. Wynn. 1999. IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J. Immunol. 162:920.
37. + cells. Adv. Immunol. 53:1.
38. Huang, H., J. Hu-Li, H. Chen, S. Z. Ben-Sasson, and W. E. Paul. 1997. IL-4 and IL-13 production in differentiated T helper type 2 cells is not IL-4 dependent. J. Immunol. 159:3731.
39. Paul, W. E. 1997. Interleukin 4: signaling mechanisms and control of T cell differentiation. Ciba Found. Symp. 204:208.
40. June, C. H., J. A. Bluestone, L. M. Nadler, and C. B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today 15:321.
41. Thompson, C. B. 1995. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 81:979.
42. Sabin, E. A., M. A. Kopf, and E. J. Pearce. 1996. Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils. J. Exp. Med. 184:1871.
43. Mosmann, T. R., H. Cherwinsky, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348.
44. Lukacs, N. W., S. W. Chensue, W. J. Karpus, P. Lincoln, C. Keefer, R. M. Strienter, and S. L. Kunkel. 1997. C-C chemokines differentially alter interleukin-4 production from lymphocytes. Am. J. Pathol. 150:1861.
45. Rumbley, C. A., H. Sugaya, S. A. Zekavat, M. E. Refaei, P. J. Perrin, and S. M. Phillips. 1999. Activated eosinophils are the major source of Th2-associated cytokines in the schistosome granuloma. J. Immunol. 162:1003.
46. Johnson, L. L., and P. C. Sayles. 1997. Interleukin-12, dendritic cells, and the initiation of host-protective mechanisms against Toxoplasma gondii. J. Exp. Med. 186:1799.
47. Kelsall, B. L., E. Stuber, M. Neurath, and W. Strober. 1996. Interleukin-12 production by dendritic cells: the role of CD40-CD40L interactions in Th1 T-cell responses. Ann. NY Acad. Sci. 795:116.
48. Rissoan, M.-C., C. Soumelis, N. Kadowaki, G. Grouard, F. Briere, R. de W. Malefyt, and Y.-J. Liu. 1999. Reciprocal control of T helper cell and dendritic cell differentiation. Science 283:1183.
49. Betts, C. J., and R. A. Wilson. 1998. Th1 cytokine mRNA expression dominates in the skin-draining lymph nodes of C57BL/6 mice following vaccination with irradiated Schistosoma mansoni cercariae. but is down-regulated upon challenge infection. Immunology 93:49.
50. Wynn, T. A., D. Jankovic, S. Hieny, A. W. Cheever, and A. Sher. 1995. IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cylokine expression. IgE production, and tissue eosinophilia. J. Immunol. 154:4701.
51. Lukacs, N. W., and D. L. Boros. 1991. Identification of larval cross-reactive and egg-specific antigens involved in granuloma formation in murine Schistosomiasis mansoni. Infect. Immun. 59:3237.
52. Cheever, A. W., F. A. Lewis, and T. A. Wynn. 1997. Schistosoma mansoni: unisexual infections sensitize mice for granuloma formation around intravenously injected eggs. Parasitol. Res. 83:57.
53. Leptak, C. L., and J. H. McKerrow. 1997. Schistosome egg granulomas and hepatic expression of TNF-α are dependent on immune priming during parasite maturation. J. Immunol. 158:301.