Restriction-mediated Differential Display (RMDD) Identifies pip92 as a Pro-apoptotic Gene Product Induced during Focal Cerebral Ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 24, Issue 2, 2004, Pages 224-236

  Schneider, Armin ^a   Fischer, Achim ^a   Weber, Daniela ^a   Von Ahsen, Oliver ^a   Scheek, Sigrid ^a   Krüger, Carola ^a   Rossner, Moritz ^a   Klaussner, Bettina ^a   Faucheron, Nadine ^a   Kammandel, Birgitta ^a   Goetz, Bernhard ^a   Herrmann, Oliver ^b   Bach, Alfred ^a   Schwaninger, Markus ^b  

^a Axaron Bioscience AG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Differential display; Focal cerebral ischemia; Gene expression; MCAO apoptosis; pip92

Indexed keywords

BIOTIN; GENE PRODUCT; RADICAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL STRAIN COS1; CONTROLLED STUDY; DIFFERENTIAL DISPLAY; ELECTROPHORESIS; GENE; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC SCREENING; HEMISPHERE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PIP92 GENE; PRIORITY JOURNAL; REPERFUSION; RESPIRATORY CHAIN; RESTRICTION MAPPING; RESTRICTION MEDIATED DIFFERENTIAL DISPLAY; UNINDEXED SEQUENCE;

EID: 10744222117     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WCB.0000104960.26014.7A     Document Type: Article

References (58)

1. Bechmann I, Diano S, Warden CH, Bartfai T, Nitsch R, Horvath TL (2002) Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol 64:363-367
2. Beck S, Pohl FM (1984) DNA sequencing with direct blotting electrophoresis. EMBO J 3:2905-2909
3. Brambrink AM, Schneider A, Noga H, Astheimer A, Gotz B, Korner I, Heimann A, Welschof M, Kempski O (2000) Tolerance-Inducing dose of 3-nitropropionic acid modulates bcl-2 and bax balance in the rat brain: a potential mechanism of chemical preconditioning. J Cereb Blood Flow Metab 20:1425-1436
4. Brenner S, Johnson M, Bridgham J, Golda G, Lloyd DH, Johnson D, Luo S, McCurdy S, Foy M, Ewan M, Roth R, George D, Eletr S, Albrecht G, Vermaas E, Williams SR, Moon K, Burcham T, Pallas M, DuBridge RB, Kirchner J, Fearon K, Mao J, Corcoran K (2000) Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nat Biotechnol 18:630-634
5. Campagne MV, Thibodeaux H, van Bruggen N, Cairns B, Lowe DG (2000) Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion. J Neurosci 20:5200-5207
6. Charles CH, Simske JS, O'Brien TP, Lau LF (1990) Pip92: a short-lived, growth factor-inducible protein in BALB/c 3T3 and PC12 cells. Mol Cell Biol 10:6769-6774
7. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
8. Chung KC, Kim SM, Rhang S, Lau LF, Gomes I, Ahn YS (2000a) Expression of immediate early gene pip92 during anisomycin-induced cell death is mediated by the JNK- and p38-dependent activation of Elk1. Eur J Biochem 267:4676-4684
9. Chung KC, Shin SW, Yoo M, Lee MY, Lee HW, Choe BK, Ahn YS (2000b) A systemic administration of NMDA induces immediate early gene pip92 in the hippocampus. J Neurochem 75:9-17
10. Chung KC, Sung JY, Ahn W, Rhim H, Oh TH, Lee MG, Ahn YS (2001) Intracellular calcium mobilization induces immediate early gene pip92 via Src and mitogen-activated protein kinase in immortalized hippocampal cells. J Biol Chem 276:2132-2138
11. Debouck C (1995) Differential display or differential dismay? Curr Opin Biotechnol 6:597-599
12. Diatchenko L, Lau YF, Campbell AP, Chenchik A, Moqadam F, Huang B, Lukyanov S, Lukyanov K, Gurskaya N, Sverdiov ED, Siebert PD. (1996) Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc Natl Acad Sci U S A 93:6025-6030
13. Doutheil J, Althausen S, Gissel C, Paschen W (1999) Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis. Brain Res Mol Brain Res 63:225-232
14. Fischer A (1995) Gene expression analysis. Patent EP 0 743 367 B1
15. Fischer A (2001) Restriction-Mediated Differential Display (RMDD). In: Current protocols in molecular biology. (Ausubel FM BR, Kingston RE, Moore DD, Seidman JG, Smith JA et al., ed): John Wiley & Sons, pp 25B.24.21-25B.24.17
16. Fischer A, Saedler H, Theissen G (1995) Restriction fragment length polymorphism-coupled domain-directed differential display: a highly efficient technique for expression analysis of multigene families. Proc Natl Acad Sci USA 92:5331-5335
17. Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier D, Warden CH (1997) Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 15:269-272
18. Gass P, Spranger M, Herdegen T, Bravo R, Kock P, Hacke W, Kiessling M (1992) Induction of FOS and JUN proteins after focal ischemia in the rat: differential effect of the N-methyl-D-aspartate receptor antagonist MK-801. Acta Neuropathol 84:545-553
19. Grishin AV, Azhipa O, Semenov I, Corey SJ (2001) Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis. Proc Natl Acad Sci USA 98:10172-10177
20. Guan J, Bennet L, George S, Wu D, Waldvogel HJ, Gluckman PD, Faull RL, Crosier PS, Gunn AJ (2001) Insulin-like growth factor-1 reduces postischemic white matter injury in fetal sheep. J Cereb Blood Flow Metab 21:493-502
21. Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, Hunter T, Karin M (1998) Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N- terminal kinases after neuronal injury. J Neurosci 18:5124-5135
22. Herdegen T, Leah JD (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev 28:370-490
23. Herrmann O, Tarabin V, Suzuki S, Attigah N, Coserea I, Schneider A, Vogel J, Prinz S, Schwab S, Monyer H, Brombacher F, Schwaninger M (2003) Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia. J Cereb Blood Flow Metab 23:406-415
24. Isenmann S, Stoll G, Schroeter M, Krajewski S, Reed JC, Bahr M (1998) Differential regulation of Bax, Bcl-2, and Bcl-X proteins in focal cortical ischemia in the rat. Brain Pathol 8:49-62; discussion 62-43
25. Kinoshita A, Noda M, Kinoshita M (2000) Differential localization of septins in the mouse brain. J Comp Neurol 428:223-239
26. Kinouchi H, Sharp FR, Hill MP, Koistinaho J, Sagar SM, Chan PH (1993) Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 13:105-115
27. Krajewski S, Mai JK, Krajewska M, Sikorska M, Mossakowski MJ, Reed JC (1995) Upregulation of bax protein levels in neurons following cerebral ischemia. J Neurosci 15:6364-6376
28. Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, Orly J, Kim SJ, Roberts AB (2000) A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nat Cell Biol 2:915-921
29. Lee NH, Weinstock KG, Kirkness EF, Earle-Hughes JA, Fuldner RA, Marmaros S, Glodek A, Gocayne JD, Adams MD, Kerlavage AR, et al. (1995) Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Proc Natl Acad Sci USA 92:8303-8307
30. Liang P, Pardee AB (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971
31. Lockhart DJ, Dong H, Byrne MC, Follettie MT, Gallo MV, Chee MS, Mittmann M, Wang C, Kobayashi M, Horton H, Brown EL (1996) Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 14:1675-1680
32. Lu A, Ran R, Parmentier-Batteur S, Nee A, Sharp FR (2002) Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia. J Neurochem 81:355-364
33. Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K, Wieloch T (2003) Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med 9:1062-1068
34. McClelland M, Welsh J (1994) RNA fingerprinting by arbitrarily primed PCR. PCR Methods Appl 4:S66-81
35. Memon SA, Petrak D, Moreno MB, Zacharchuk CM (1995) A simple assay for examining the effect of transiently expressed genes on programmed cell death. J Immunol Methods 180:15-24
36. Negre-Salvayre A, Hirtz C, Carrera G, Cazenave R, Troly M, Salvayre R, Penicaud L, Casteilla L (1997) A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. Faseb J 11:809-815
37. O'Brien RJ, Xu D, Petralia RS, Steward O, Huganir RL, Worley P (1999) Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product Narp. Neuron 23:309-323
38. Ohki EC, Tilkins ML, Ciccarone VC, Price PJ (2001) Improving the transfection efficiency of post-mitotic neurons. J Neurosci Methods 112:95-99
39. Paschen W, Linden T, Doutheil J (1998) Effects of transient cerebral ischemia on hsp40 mRNA levels in rat brain. Brain Res Mol Brain Res 55:341-344
40. Prashar Y, Weissman SM (1996) Analysis of differential gene expression by display of 3′ end restriction fragments of cDNAs. Proc Natl Acad Sci USA 93:659-663
41. Richard D, Rivest R, Huang Q, Bouillaud F, Sanchis D, Champigny O, Ricquier D (1998) Distribution of the uncoupling protein 2 mRNA in the mouse brain. J Comp Neurol 397:549-560
42. Scheel J, Von Brevern MC, Horlein A, Fischer A, Schneider A, Bach A (2002) Yellow pages to the transcriptome. Pharmacogenomics 3:791-807
43. Schena M, Shalon D, Davis RW, Brown PO (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270:467-470
44. Schneider A, Martin-Villalba A, Weih F, Vogel J, Wirth T, Schwaninger M (1999) NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med 5:554-559
45. Schwarz DA, Barry G, Mackay KB, Manu F, Naeve GS, Vana AM, Verge G, Conlon PJ, Foster AC, Maki RA (2002) Identification of differentially expressed genes induced by transient ischemic stroke. Brain Res Mol Brain Res 101:12-22
46. Serrano J, Alonso D, Encinas JM, Lopez JC, Fernandez AP, Castro-Blanco S, Fernandez-Vizarra P, Richart A, Bentura ML, Santacana M, Uttenthal LO, Cuttitta F, Rodrigo J, Martinez A (2002) Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat. Neuroscience 109:717-731
47. Sexton PM, Albiston A, Morfis M, Tilakaratne N (2001) Receptor activity modifying proteins. Cell Signal 13:73-83
48. Sharp FR, Lu A, Tang Y, Millhorn DE (2000) Multiple molecular penumbras after focal cerebral ischemia. J Cereb Blood Flow Metab 20:1011-1032
49. Shimkets RA, Lowe DG, Tai JT, Sehl P, Jin H, Yang R, Predki PF, Rothberg BE, Murtha MT, Roth ME, Shenoy SG, Windemuth A, Simpson JW, Simons JF, Daley MP, Gold SA, McKenna MP, Hillan K, Went GT, Rothberg JM (1999) Gene expression analysis by transcript profiling coupled to a gene database query. Nat Biotechnol 17:798-803
50. Soriano MA, Tessier M, Certa U, Gill R (2000) Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J Cereb Blood Flow Metab 20:1045-1055
51. Sutcliffe JG, Foye PE, Erlander MG, Hilbush BS, Bodzin LJ, Durham JT, Hasel KW (2000) TOGA: an automated parsing technology for analyzing expression of nearly all genes. Proc Natl Acad Sci USA 97:1976-1981
52. Trendelenburg G, Prass K, Priller J, Kapinya K, Polley A, Muselmann C, Ruscher K, Kannbley U, Schmitt AO, Castell S, Wiegand F, Meisel A, Rosenthal A, Dirnagl U (2002) Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia. J Neurosci 22:5879-5888
53. Tsui CC, Copeland NG, Gilbert DJ, Jenkins NA, Barnes C, Worley PF (1996) Narp, a novel member of the pentraxin family, promotes neurite outgrowth and is dynamically regulated by neuronal activity. J Neurosci 16:2463-2478
54. Velculescu VE, Zhang L, Vogelstein B, Kinzler KW (1995) Serial analysis of gene expression. Science 270:484-487
55. Watanabe K, Takayasu M, Noda A, Hara M, Takagi T, Suzuki Y, Yoshia J (2001) Adrenomedullin reduces ischemic brain injury after transient middle cerebral artery occlusion in rats. Acta Neurochir (Wien) 143:1157-1161
56. Welsh J, Chada K, Dalal SS, Cheng R, Ralph D, McClelland M (1992) Arbitrarily primed PCR fingerprinting of RNA. Nucleic Acids Res 20:4965-4970
57. Yenari MA, Fink SL, Sun GH, Chang LK, Patel MK, Kunis DM, Onley D, Ho DY, Sapolsky RM, Steinberg GK (1998) Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. Ann Neurol 44:584-591
58. Yrjanheikki J, Koistinaho J, Copin JC, de Crespigny A, Moseley ME, Chan PH (2000) Spreading depression-induced expression of c-fos and cyclooxygenase-2 in transgenic mice that overexpress human copper/zinc-superoxide dismutase. J Neurotrauma 17:713-718