Effects of transient cerebral ischemia on hsp40 mRNA levels in rat brain

Molecular Brain Research

Volumn 55, Issue 2, 1998, Pages 341-344

  Paschen, Wulf ^a   Linden, Thomas ^a   Doutheil, Jens ^a  

^a MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

Author keywords

Cortex; Gene expression; Hippocampus; Hsp40; Ischemia; Quantitative PCR; Rat brain

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DOUBLE STRANDED RNA; HEAT SHOCK PROTEIN; INTERFERON; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; HIPPOCAMPUS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; RAT; REVERSE TRANSCRIPTION; TRANSIENT ISCHEMIC ATTACK;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; BRAIN; HEAT-SHOCK PROTEINS; HSP40 HEAT-SHOCK PROTEINS; ISCHEMIC ATTACK, TRANSIENT; MALE; MOLECULAR SEQUENCE DATA; RATS; RATS, WISTAR; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032052171     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00027-8     Document Type: Article

References (21)

1. Bodsch W., Takahashi K., Barbier A., Grosse Ophoff B., Hossmann K.-A. Cerebral protein synthesis and ischemia. Progr. Brain Res. 63:1985;197-210.
2. Caplan A.J., Cyr D.M., Douglas M.G. Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins. Mol. Biol. Cell. 4:1993;555-563.
3. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acidic guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
4. DeGracia D.J., Neumar R.W., White B.C., Krause G.S. Global brain ischemia and reperfusion: modifications in eukaryotic initiation factors associated with inhibition of translational initiation. J. Neurochem. 67:1996;2005-2012.
5. Der S.D., Yang Y.-L., Weissmann C., Williams B.R.G. A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc. Natl. Acad. Sci. U.S.A. 94:1997;3283-3297.
6. Frydman J., Nimmesgern E., Ohtsuka K., Hartl U. Folding of nascent polypeptide chains in high molecular mass assembly with molecular chaperons. Nature. 370:1994;111-117.
7. Gissel C., Doutheil J., Paschen W. Temporal analysis of changes in neuronal c-fos mRNA levels induced by depletion of endoplasmic reticulum calcium stores: effect of clamping cytoplasmic calcium activity at resting levels. J. Neurochem. 69:1997;2538-2545.
8. He B., Gross M., Roizman B. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. U.S.A. 94:1997;843-848.
9. Höhfeld J., Minami Y., Hartl F.-U. Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle. Cell. 83:1995;589-598.
10. Lee T.G., Tomita J., Hovanessian A.G., Katze M.G. Characterization and regulation of the 58,000-Da cellular inhibitor of the interferone-induced, dsRNA-activated protein kinase. J. Biol. Chem. 67:1992;14238-14243.
11. Melville M.W., Hansen W.J., Freeman B.C., Welch W.J., Katze M.G. The molecular chaperone hsp40 regulates the activity of P58(IPK) the cellular inhibitor of PKR. Proc. Natl. Acad. Sci. U.S.A. 94:1997;97-102.
12. Minami Y., Höhfeld J., Ohtsuka K., Hartl F.-U. Regulation of the heat-shock protein 70 reaction cycle by the mammalian DnaJ homolog, Hsp40. J. Biol. Chem. 271:1996;19617-19624.
13. Ohtsuka K. Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ. Biochem. Biophys. Res. Commun. 197:1993;235-240.
14. O'Malley R.P., Mariano T.M., Siekierka J., Mathews M.B. A mechanism for the control of protein synthesis by adenovirus VA RNAI. Cell. 44:1986;391-400.
15. Paschen W. Disturbances in calcium homeostasis within the endo- plasmic reticulum may contribute to the development of ischemic cell damage. Med. Hypoth. 47:1996;283-288.
16. Paschen W., Doutheil J., Gissel C., Treiman M. Depletion of neuronal endoplasmic reticulum calcium stores by thapsigargin: effect on protein synthesis. J. Neurochem. 67:1996;1735-1743.
17. Prostko C.R., Dholakia J.N., Brostrom M.A., Brostrom C.O. Activation of the double-stranded RNA-regulated protein kinase by depletion of endoplasmic reticulum calcium stores. J. Biol. Chem. 270:1995;6211-6215.
18. Samuel C.E. The eIF-2alpha protein kinases, regulators of translation in eukaryotes from yeast to humans. J. Biol. Chem. 268:1993;7603-7606.
19. Schmidt-Kastner R., Paschen W., Grosse-Ophoff B., Hossmann K.-A. A modified four-vessel occlusion model for introducing incomplete forebrain ischemia in rats. Stroke. 20:1989;938-946.
20. Strom T., Jagus R., Darveau A. The 58-kDa inhibitor of the interferone-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties. Proc. Natl. Acad. Sci. U.S.A. 91:1994;4278-4282.
21. Yamane M., Hattori H., Sugito K., Hayashi Y., Tohnai I., Minoru U., Nishizawa K., Ohtsuka K. Cotranslocation and colocalization of hsp40 (DnaJ) with hsp70 (DnaK) in mammalian cells. Cell Struct. Funct. 20:1995;157-166.