Amiloride potentiates TRAIL-induced tumor cell apoptosis by intracellular acidification-dependent Akt inactivation

Biochemical and Biophysical Research Communications

Volumn 326, Issue 4, 2005, Pages 752-758

  Cho, Young Lai ^a   Lee, Kwang Soon ^a   Lee, Seon Jin ^a   Namkoong, Seung ^a   Kim, Young Mi ^a   Lee, Hansoo ^a   Ha, Kwon Soo ^a   Han, Jeong A ^a   Kwon, Young Guen ^b   Kim, Young Myeong ^a  

^a Kangwon National University   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Amiloride; Apoptosis; Caspases; Intracellular acidification; TRAIL

Indexed keywords

AMILORIDE; CASPASE 3; CASPASE 8; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; PROTEIN SERINE KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ACIDIFICATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MITOCHONDRION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; TUMOR CELL;

EID: 10644275302     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.11.109     Document Type: Article

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