Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway

Journal of Leukocyte Biology

Volumn 72, Issue 1, 2002, Pages 207-216

  Hsu, Ming Jen ^a   Lee, Shiuh Sheng ^b   Lin, Wan Wan ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Caspase activation; Human; Neutrophil apoptosis; PS G

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; FAS ANTIGEN; GANODERMA LUCIDUM EXTRACT; GLUCAN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; POLYSACCHARIDE; PROTEIN KINASE B; WORTMANNIN;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENTIATION; DRUG PURIFICATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; GANODERMA LUCIDUM; HUMAN; HUMAN CELL; NEUTROPHIL; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD95; ANTIOXIDANTS; APOPTOSIS; BETA-GLUCANS; CASPASES; CELL NUCLEUS; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLUCANS; HUMANS; KINETICS; NEUTROPHILS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REISHI; SIGNAL TRANSDUCTION;

GANODERMA; GANODERMA LUCIDUM;

EID: 0036659521     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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