Estrogen Elicits Cytochrome P450-Mediated Flow-Induced Dilation of Arterioles in NO Deficiency: Role of PI3K-Akt Phosphorylation in Genomic Regulation

Circulation Research

Volumn 94, Issue 2, 2004, Pages 245-252

  Huang, An ^a   Sun, Dong ^a   Wu, Zhiping ^a   Yan, Changdong ^a   Carroll, Mairead A ^a   Jiang, Houli ^a   Falck, John R ^b   Kaley, Gabor ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Akt; Cytochrome P450; Estradiol; Flow induced dilation; Transcription

Indexed keywords

CYTOCHROME P450; EPOXYICOSATRIENOIC ACID; ESTRADIOL; ESTROGEN; FULVESTRANT; INDOMETACIN; MICONAZOLE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROSTAGLANDIN; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTERY TONE; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; GAS CHROMATOGRAPHY; GENE CONTROL; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SHEAR STRESS; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ARTERIOLES; CYTOCHROME P-450 ENZYME SYSTEM; ENDOTHELIUM, VASCULAR; ENZYME INDUCTION; ENZYME INHIBITORS; ESTRADIOL; FEMALE; HEMORHEOLOGY; HEXANOIC ACIDS; INDOMETHACIN; MALE; MICONAZOLE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; TRANSCRIPTION, GENETIC; VASODILATION;

EID: 1042302781     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000111525.96232.46     Document Type: Article

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