17β-Estradiol restores endothelial nitric oxide release to shear stress in arterioles of male hypertensive rats

Circulation

Volumn 101, Issue 1, 2000, Pages 94-100

  Huang, An ^a   Dong, Sun ^a   Koller, Akos ^a   Kaley, Gabor ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Endothelium; Hormones; Receptors; Vasodilation

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ADENOSINE; AMINOGUANIDINE; CALCIMYCIN; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; NORADRENALIN; ANTIESTROGEN; DRUG DERIVATIVE; GUANIDINE DERIVATIVE;

ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD FLOW; BLOOD VESSEL DIAMETER; BLOOD VESSEL WALL; CONTROLLED STUDY; GRACILIS MUSCLE; MALE; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR ENDOTHELIUM; VASODILATATION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HYPERTENSION; MECHANICAL STRESS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; VASOCONSTRICTION;

ADENOSINE; ANIMALS; ARTERIOLES; CALCIMYCIN; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; ENDOTHELIUM, VASCULAR; ESTRADIOL; ESTROGEN ANTAGONISTS; FEMALE; GUANIDINES; HYPERTENSION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; NOREPINEPHRINE; RATS; RATS, INBRED SHR; RECEPTORS, ESTROGEN; STRESS, MECHANICAL; VASOCONSTRICTION;

EID: 0034602611     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.1.94     Document Type: Article

References (38)

1. Kauser K, Rubanyi GM. Potential cellular signaling mechanisms mediating upregulation of endothelial nitric oxide production by estrogen. J Vasc Res. 1997;34:229-236.
2. Gisclard V, Miller VM, Vanhoutte PM. Effect of 17β-estradiol on endothelium dependent responses in the rabbit. J Pharmacol Exp Ther. 1988; 244:19-22.
3. Kauser K, Rubanyi GM. Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension. 1995;25: 517-523.
4. Kauser K, Rubanyi GM. 17β-Estradiol augments endothelial nitric oxide production in the aortae of male spontaneously hypertensive rats. In: Moncada S, Feelisch M, Busse R, Miggs EA, eds. The Biology of Nitric Oxide. London, UK: Portland Press; 1995:13-18.
5. Kauser K, Sonnenberg D, Mertens H, Werner M, Wilson K, Polokoff R, Vergona R, Rubanyi GM. Vascular protective effect of 17β-estradiol in high cholesterol-fed, ovariectomized rabbits. FASEB J. 1995;9:I-A854. Abstract.
6. Nekooeian AA, Pang CCY. Estrogen restores role of basal nitric oxide in control of vascular tone in rats with chronic heart failure. Am J Physiol. 1998;274(Heart Circ Physiol 43):H-2094-H2099.
7. Sudhir K, Jennings GL, Funder JW, Komesaroff PA. Estrogen enhances basal nitric oxide release in the forearm vasculature in perimenopausal women. Hypertension. 1996;28:330-334.
8. Gilligan DM, Quyyumi RO, Cannon RO III. Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation. 1994;89:2545-2551.
9. Cockell AP, Poston L. Flow-mediated vasodilation is enhanced in normal pregnancy but reduced in preeclampsia. Hypertension. 1997;30:247-251.
10. Rosselli M, Imthurn B, Keller PJ, Jacson EK, Dubey PK. Circulating nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol and norethisterone acetate: a two-year follow-up study. Hypertension. 1995;25(pt 2):848-853.
11. Sudhir K, Chou TM, Mullen WL, Hausmann D, Collins P, Yock PG, Chatterjee K. Mechanisms of estrogen-induced vasodilation: in vivo studies in canine coronary conductance and resistance arteries. J Am Coll Cardiol. 1995;26:807-814.
12. Kauser K, Rubanyi GM. 17β-Estradiol and endothelial nitric oxide synthase. Endothelium. 1994;2:203-208.
13. Huang A, Sun D, Koller A, Kaley G. Gender difference in myogenic tone of rat arterioles is due to estrogen-induced, enhanced release of NO. Am J Physiol. 1991;272(heart Circ Physiol 41):H1804-H1809.
14. Huang A, Sun D, Koller A, Kaley G. Gender difference in flow dependent dilation and regulation of shear stress: role of estrogen and nitric oxide. Am J Physiol. 1998;275(Regul Integr Comp Physiol 44): R1571-R1577.
15. Koller A, Kaley G. Endothelial regulation of wall shear stress and blood flow in skeletal muscle microcirculation. Am J Physiol. 1991;260(Heart Circ Physiol 28):H862-H868.
16. Koller A, Sun D, Huang A, Kaley G. Corelease of nitric oxide and prostaglandins mediates flow-induced dilation of rat gracilis muscle arterioles. Am J Physiol. 1994;267(Heart Circ Physiol 36):H326-H332.
17. Koller A, Kaley G. Shear stress dependent regulation of vascular resistance in health and disease: role of endothelium. Endothelium. 1996; 4:247-272.
18. Huang A, Koller A. Both nitric oxide and prostaglandin-mediated responses are impaired in skeletal muscle arterioles of hypertensive rats. J Hypertens. 1996;14:887-895.
19. Huang A, Sun D, Kaley G, Koller A. Estrogen maintains nitric oxide synthesis in arterioles of female hypertensive rats. Hypertension. 1997; 29:1351-1356.
20. Koller A, Huang A. Impaired nitric oxide-mediated flow-induced dilation in arterioles of spontaneously hypertensive rats. Circ Res. 1994;74:416-421.
21. Koller A, Huang A. Shear stress-induced dilation is attenuated in skeletal muscle arterioles of hypertensive rats. Hypertension. 1995;25(pt 2):752-763.
22. Huang A, Sun D, Kaley G, Koller A. Estrogen preserves regulation of shear stress by nitric oxide in arterioles of female hypertensive rats. Hypertension. 1998;31(pt 2):309-314.
23. Bush TL, Barrett-Connor E, Cowan LD, Criqui MH, Wallace RB, Suchindran CM, Tyroler HA, Rifkind BM. Cardiovascular mortality and non-contraceptive estrogen use in women: results from the Lipid Research Clinics Program follow-up study. Circulation. 1987;75: 1002-1009.
24. Wakeling AE, Dukes M, Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991;51:3867-3873.
25. Raju U, Koumenis C, Nunez-Regueiro M, Eskin A. Alteration of the phase and period of a circadian oscillator by a reversible transcription inhibitor. Science. 1991;9:673-675.
26. Binko J, Majewski H. 17β-Estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS. Am J Physiol. 1997; 274(Heart Circ Physiol 43):H853-H859.
27. Misko TP, Moore WM, Kasten TP, Nickols GA, Corbett JA, Tilton RG, McDaniel ML, Williamson JR, Currie MG. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol. 1993;233:119-125.
28. Penotti M, Nencioni T, Gabrielli L, Farina M, Castiglioni E, Polvani F. Blood flow variations in internal carotid and middle cerebral arteries induced by postmenopausal hormone replacement therapy. Am J Obstet Gynecol. 1993;169:1226-1232.
29. Van Buren GA, Yang D, Clark KE. Estrogen-induced uterine vasodilation is antagonized by L-nitro-arginine methyl ester, an inhibitor of nitric oxide synthesis. Am J Obstet Gynecol. 1992;167:828-833.
30. Arnal JF, Clamens S, Pechet C, Negre-Salvayre A, Allera C, Girolami JP, Salvayre R, Bayard F. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci USA. 1996;93:4108-4113.
31. Ohashi Y, Kawashima S, Hirata K, Yamashita T, Ishida T, Inoue N, Sakoda T, Kurihara H, Yazaki Y, Yokoyama M. Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. J Clin Invest. 1998;102: 2061-2071.
32. Moncada S, Rees DD, Schultz R, Palmer RMJ. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc Natl Acad Sci U S A. 1991;88:2166-2170.
33. Vencov C, Rankin A, Vaughan D. Identification of authentic estrogen receptor in cultured endothelial cells: a potential mechanism for steroid hormone regulation of endothelial function. Circulation. 1996;94: 727-733.
34. Weiner CP, Lizasoain I, Knowles SA, Charles IG, Moncada S. Induction of calcium-dependent nitric oxide synthase by hormones. Proc Natl Acad Sci U S A. 1994;91:5212-5216.
35. Carson-Jurica MA, Schrader WY, O'Malley BW. Steroid receptor family: structure and functions. Endocr Rev. 1990;11:201-220.
36. Rubanyi GM, Freay AD, Kauser K, Sukovich D, Burton G, Lubahn DB, Couse JF, Curtis SW, Korach KS. Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta: gender difference and effect of estrogen receptor gene disruption. J Clin Invest. 1997;99:2429-2437.
37. Chen Z, Yuhanna IS, Galcheva-Gargova Z, Karas RH, Mendelsohn ME, Shaul PW. Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J Clin Invest. 1999;103: 401-406.
38. 2+ mobilization. Circ Res. 1997;81: 885-892.