Estrogen Preserves Regulation of Shear Stress by Nitric Oxide in Arterioles of Female Hypertensive Rats

Hypertension

Volumn 31, Issue 1, 1998, Pages 309-314

  Huang, H ^a   Sun, Dong ^a   Kaley, Gabor ^a   Koller, Akos ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; INDOMETACIN; N(G) NITROARGININE; NITRIC OXIDE; ESTRADIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL WALL; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FLOW KINETICS; GRACILIS MUSCLE; HORMONAL REGULATION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; SHEAR STRESS; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; ARTERIOLE; BLOOD; BLOOD PRESSURE; BODY WEIGHT; ESTROGEN THERAPY; FEMALE; HEART RATE; HISTOLOGY; HYPERTENSION; IN VITRO STUDY; MALE; MECHANICAL STRESS; ORGAN SIZE; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT; SKELETAL MUSCLE; UTERUS; VASCULAR SMOOTH MUSCLE; VASCULARIZATION; VASODILATATION;

ANIMALS; ARTERIOLES; BLOOD PRESSURE; BODY WEIGHT; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; HEART RATE; HYPERTENSION; INDOMETHACIN; MALE; MUSCLE, SKELETAL; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITROARGININE; ORGAN SIZE; OVARIECTOMY; RATS; RATS, INBRED SHR; SEX CHARACTERISTICS; STRESS, MECHANICAL; UTERUS; VASODILATION;

EID: 0031607366     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.31.1.309     Document Type: Article

References (29)

1. Isles CG, Hole DJ, Hawthorne VM, Lever AF. Relation between coronary risk and coronary mortality in women of the Renfew and Paisley survey: comparison with men. Lancet. 1992;339:702-706.
2. Nabulsi AA, Folsom AR, White A, Patsch W, Heiss G, Wu KK, Szklo M. Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. N Engl J Med. 1993;328:1069-1075.
3. von Eiff AW, Gogolin E, Jacobs U, Neus H. Ambulatory blood pressure in children followed for 3 years: influence of sex and family history on hypertension. Clin. Exp. Hypertens. 1986;8:577-581.
4. Iams SG, Wexler BC. Inhibition of the development of spontaneous hypertension in SH rats by gonadectomy or estradiol. J Lab Clin Med. 1979;10:608-616.
5. Dahl LK, Knudsen KD, Ohanian EV, Muirhead M, Tuthill R. Role of gonads in hypertension prone rats. J Exp Med. 1975;142:748-759.8.
6. Hutchins PM, Dusseau JW, Marc MC, Green PW. The role of arteriolar structural changes in hypertension. In: Henrich H, ed. Microvascular Aspects of Spontaneous Hypertension. Bern. Switzerland: H. Huber Publishers; 1982:41-53.
7. Folkow B. Structural factor in primary and secondary hypertension. Hypertension. 1990;16:89-101.
8. Kauser, K, Rubanyi GM. Gender difference in bioassayable endothelium-derived NO from isolated rat aortae. Am J Physiol. 1994;267:H2311-H2317.
9. Jiang C, Sarrel PM, Poole-Wilson PA, Collins P. Acute effect of 17beta-estradiol on rabbit coronary artery contractile responses to endothelin-1. Am J Physiol. 1992;263:H271-H275.
10. Gisclard V, Miller VM, Vanhoutte PM. Effect of 17beta-estradiol on endothelium dependent responses in the rabbit. J Pharmacol Exp Ther. 1988;244:19-22.
11. Hayashi T, Fukuto JM, Ignarro LJ, Chaudburi G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc Natl Acad Sci U S A. 1992;89:11259-11263.
12. William SP, Shackford DP, Iams SG, Mustafa SJ. Endothelium-dependent relaxation in estrogen-treated spontaneously hypertensive rats. Eur J Pharmacol. 1988;145:205-207.
13. Kauser K, Rubanyi GM. Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension. 1995;25(pt 1):517-523.
14. Rosselli M, Imthurn B, Keller PJ, Jacson EK, Dubey RK. Circulating nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17beta-estradiol and norethisterone acetate: a two-year follow-up study. Hypertension. 1995;25(pt 2):848-853.
15. Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG, Moncada S. Induction of calcium-dependent no synthases by sex hormones. Proc Natl Acad Sci U S A. 1994;91:5212-5216.
16. Sudhir K, Jennings GL, Funder JW, Komesaroff PA. Estrogen enhances basal nitric oxide release in the forearm vasculature in perimenopausal women. Hypertension. 1996;28:330-334.
17. Sun D, Huang A, Koller A, Kaley G. Flow-dependent dilation and myogenic constriction interact to establish the resistance of skeletal muscle arterioles. Microcirculation. 1995;2:289-295.
18. Rees, DD, Palmer RMJ, Moncada S. Role of endothelium derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci U S A. 1989;86:3375-3378.
19. Huang, A., Sun D, Koller A, Kaley G. Gender difference in myogenic tone of rat arterioles is due to estrogen-induced, enhanced release of nitric oxide. Am J Physiol. 1997;272:H1804-H1809.
20. Huang A, Sun D, Koller A. Endothelial dysfunction augments myogenic arteriolar constriction in hypertension. Hypertension. 1993;22:913-921.
21. Huang A, Koller A. Both nitric oxide and prostaglandin-mediated responses are impaired in skeletal muscle arterioles of hypertensive rats. J Hypertens. 1996;14:887-895.
22. Koller A, Huang A. Impaired nitric oxide-mediated flow-induced dilation in arterioles of spontaneously hypertensive rats. Circ Res. 1994;74:416-421.
23. Huang A, Sun D, Kaley G, Koller A. Estrogen maintains nitric oxide synthesis in arterioles of female hypertensive rats. Hypertension. 1997;29:1351-1356.
24. Koller A, Sun D, Huang A, Kaley G. Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles. Am J Physiol. 1994;267:H326-H332.
25. Koller A, Huang A. Shear stress-induced dilation is attenuated in skeletal muscle arterioles of hypertensive rats. Hypertension. 1995;25:(pt 2):758-763.
26. Meyer MC, Cummings K, Osol G. Estrogen replacement attenuates resistance artery adrenergic sensitivity via endothelial vasodilators. Am J Physiol. 1997;272:H2264-H2270.
27. 2 enhance arteriolar myogenic tone in hypertension. Hypertension. 1997;30:1210-1215.
28. Brosnihan KB, Moriguchi A, Nakamoto H, Dean RH, Ganten D, Ferrario CM. Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene. Am J Hypertens. 1994;7:576-582.
29. Heog JM, Willis LR, Weinberger MH. Estrogen attenuation of the development of hypertension in spontaneous hypertension rats. Am J Physiol. 1977;233:H369-H373.