Flow-induced dilation of human coronary arterioles important role of Ca2+-activated K+ channels

Circulation

Volumn 103, Issue 15, 2001, Pages 1992-1998

  Miura, Hiroto ^a,b,c,d   Wachtel, Ruth E ^a,b,c,d   Liu, Yanping ^a,b,c,d   Loberiza Jr , Fausto R ^a,b,c,d   Saito, Takashi ^a,b,c,d   Miura, Mamoru ^a,b,c,d   Gutterman, David D ^a,b,c,d  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d AKITA UNIVERSITY   (Japan)

Author keywords

Blood flow; Microcirculation; Vasodilation

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CHARYBDOTOXIN; CYTOCHROME P450; GLIBENCLAMIDE; INDOMETACIN; MICONAZOLE; NITRIC OXIDE; POTASSIUM CHANNEL; POTASSIUM CHLORIDE; POTASSIUM ION; PROSTAGLANDIN; TETRYLAMMONIUM;

ADULT; AGE; AGED; ARTERY CATHETERIZATION; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; CORONARY ARTERY DISEASE; DRUG EFFECT; FEMALE; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; MAJOR CLINICAL STUDY; MALE; MICROCIRCULATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL; STRESS; VASCULAR SMOOTH MUSCLE; VASODILATATION;

EID: 0035901576     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.15.1992     Document Type: Article

References (35)

1. Crucial role of endothelium in the vasodilator response to increased flow in vivo
2. Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries
3. Endothelium-dependent, flow-induced dilation of isolated coronary arterioles
4. Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels
5. Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro
6. Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans
7. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo
8. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
9. Cytochrome P450 2C is an EDHF synthase in coronary arteries
10. + channels
11. Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles
12. Flow-mediated vasodilation of human epicardial coronary arteries: Effect of inhibition of nitric oxide synthesis
13. Nitric oxide-mediated flow-dependent dilation is impaired in coronary arteries in patients with coronary spastic angina
14. Evidence that mechanisms dependent and independent of nitric oxide mediate endothelium-dependent relaxation to bradykinin in human small resistance-like coronary arteries
15. Pharmacologic activation of the human coronary microcirculation in vitro: Endothelium-dependent dilation and differential responses to acetylcholine
16. Effect of reduced oxygen availability upon myogenic depolarization and contraction of cat middle cerebral artery
17. Characterization of endothelium-derived hyperpolarizing factor as a cytochrome P450-derived arachidonic acid metabolite in mammals
18. The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation
19. + currents in human coronary artery vascular smooth muscle cells
20. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
21. Modulation of cerebral arteriolar diameter by intraluminal flow and pressure
22. Nitric oxide activity in the atherosclerotic human coronary circulation
23. Endothelium-dependent relaxation to arachidonic acid in porcine coronary artery: Is there a fourth pathway?
24. Pathophysiological consequences of atherosclerosis extend into the coronary microcirculation: Restoration of endothelium-dependent responses by L-arginine
25. Enhanced role of potassium channels in relaxations to acetylcholine in hypercholesterolemic rabbit carotid artery
26. Endothelium-mediated coronary blood flow modulation in humans: Effects of age, atherosclerosis, hypercholesterolemia, and hypertension
27. Microvascular distribution of coronary vascular resistance in beating left ventricle
28. Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery
29. 2+ of calf pulmonary artery endothelial cells
30. Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells
31. Vasoconstriction and increased flow: Two principal mechanisms of shear stress-dependent endothelial autacoid release
32. + channels by cytochrome P-450 inhibitors
33. 2+ signalling pathways
34. Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein
35. Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation