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Volumn 112, Issue 2, 2004, Pages 238-256

A framework for assessing risks to children from exposure to environmental agents

Author keywords

Children's health; Developmental toxicity; Framework; Life stage; Risk assessment; Toxicodynamics; Toxicokinetics

Indexed keywords

TOXIC SUBSTANCE;

EID: 1042292061     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.6182     Document Type: Article
Times cited : (105)

References (88)
  • 1
    • 0033910788 scopus 로고    scopus 로고
    • Workshop to identify critical windows of exposure for children's health: Neurobehavioral work group summary
    • Adams J, Barone S Jr, LaMantia A, Philen R, Rice DC, Spear L, et al. 2000. Workshop to identify critical windows of exposure for children's health: neurobehavioral work group summary. Environ Health Perspect 108:535-544.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 535-544
    • Adams, J.1    Barone Jr., S.2    LaMantia, A.3    Philen, R.4    Rice, D.C.5    Spear, L.6
  • 2
    • 0034018166 scopus 로고    scopus 로고
    • Development of neonatal Th1/Th2 function
    • Adkins B. 2000. Development of neonatal Th1/Th2 function. Int Rev Immunol 19:157-171.
    • (2000) Int. Rev. Immunol. , vol.19 , pp. 157-171
    • Adkins, B.1
  • 3
    • 0033941397 scopus 로고    scopus 로고
    • Critical windows of exposure for children's health: Cancer in human epidemiological studies and neoplasms in experimental animal models
    • Anderson LM, Diwan BA, Fear NT, Roman E. 2000. Critical windows of exposure for children's health: cancer in human epidemiological studies and neoplasms in experimental animal models. Environ Health Perspect 108:573-594.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 573-594
    • Anderson, L.M.1    Diwan, B.A.2    Fear, N.T.3    Roman, E.4
  • 4
    • 0024515493 scopus 로고
    • Modification of transplacental tumorigenesis by 3-methyl-cholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone
    • Anderson LM, Jones AB, Riggs CW, Kovatch RM. 1989. Modification of transplacental tumorigenesis by 3-methyl-cholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone. Cancer Res 49:1676-1681.
    • (1989) Cancer Res. , vol.49 , pp. 1676-1681
    • Anderson, L.M.1    Jones, A.B.2    Riggs, C.W.3    Kovatch, R.M.4
  • 6
    • 0342756766 scopus 로고    scopus 로고
    • Workshop to identify critical windows of exposure for children's health: Cardiovascular and endocrine work group summary
    • Barr M Jr, DeSesso JM, Lau CS, Osmond C, Ozanne SE, Sadler TW, et al. 2000. Workshop to identify critical windows of exposure for children's health: cardiovascular and endocrine work group summary. Environ Health Perspect 108:569-571.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 569-571
    • Barr Jr., M.1    DeSesso, J.M.2    Lau, C.S.3    Osmond, C.4    Ozanne, S.E.5    Sadler, T.W.6
  • 7
    • 0035851009 scopus 로고    scopus 로고
    • Gender-based profiles of developmental immunotoxicity to lead in the rat: Assessment in juveniles and adults
    • Bunn TL, Parsons PJ, Kao E, Dietert RR. 2001a. Gender-based profiles of developmental immunotoxicity to lead in the rat: assessment in juveniles and adults. J Toxicol Environ Health 64:101-118.
    • (2001) J. Toxicol. Environ. Health , vol.64 , pp. 101-118
    • Bunn, T.L.1    Parsons, P.J.2    Kao, E.3    Dietert, R.R.4
  • 8
    • 0035159020 scopus 로고    scopus 로고
    • Exposure to lead during critical windows of embryonic development: Differential outcome based on stage of exposure and gender
    • Bunn TL, Parsons PJ, Kao E, Dietert RR. 2001b. Exposure to lead during critical windows of embryonic development: differential outcome based on stage of exposure and gender. Toxicol Sci 64:57-66.
    • (2001) Toxicol. Sci. , vol.64 , pp. 57-66
    • Bunn, T.L.1    Parsons, P.J.2    Kao, E.3    Dietert, R.R.4
  • 9
    • 0028349087 scopus 로고
    • Computer simulation of the lactational transfer of tetrachloroethylene in rats using a physiologically-based model
    • Byczkowski JZ, Kinkead ER, Leahy HF, Randall GM, Fisher JW. 1994. Computer simulation of the lactational transfer of tetrachloroethylene in rats using a physiologically-based model. Toxicol Appl Pharmacol 125:228-236.
    • (1994) Toxicol. Appl. Pharmacol. , vol.125 , pp. 228-236
    • Byczkowski, J.Z.1    Kinkead, E.R.2    Leahy, H.F.3    Randall, G.M.4    Fisher, J.W.5
  • 10
    • 0032894142 scopus 로고    scopus 로고
    • Persistent effect of in utero meso-2,3-dimercaptosuccinic acid (DMSA) on immune function and lead-induced immunotoxicity
    • Chen S, Golemboski KA, Sanders FS, Dietert RR. 1999. Persistent effect of in utero meso-2,3-dimercaptosuccinic acid (DMSA) on immune function and lead-induced immunotoxicity. Toxicology 132:67-79.
    • (1999) Toxicology , vol.132 , pp. 67-79
    • Chen, S.1    Golemboski, K.A.2    Sanders, F.S.3    Dietert, R.R.4
  • 11
    • 0033177872 scopus 로고    scopus 로고
    • Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics
    • Clewell HJ, Gearhart JM, Gentry PR, Covington TR, VanLandingham CB, Crump KS, et al. 1999. Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics. Risk Anal 19:547-558.
    • (1999) Risk Anal. , vol.19 , pp. 547-558
    • Clewell, H.J.1    Gearhart, J.M.2    Gentry, P.R.3    Covington, T.R.4    VanLandingham, C.B.5    Crump, K.S.6
  • 12
    • 0010995012 scopus 로고    scopus 로고
    • Executive Order 13045. Protection of Children from Environmental Health Risks and Safety Risks
    • Clinton WJ. 1997. Executive Order 13045. Protection of Children from Environmental Health Risks and Safety Risks. Fed Reg 62:19883-19888.
    • (1997) Fed. Reg. , vol.62 , pp. 19883-19888
    • Clinton, W.J.1
  • 13
    • 0031951930 scopus 로고    scopus 로고
    • Onset of xenobiotic metabolism in children: Toxicological implications
    • Cresteil T. 1998. Onset of xenobiotic metabolism in children: toxicological implications. Food Addit Contam 15:45-51.
    • (1998) Food Addit. Contam. , vol.15 , pp. 45-51
    • Cresteil, T.1
  • 14
    • 0033939623 scopus 로고    scopus 로고
    • Workshop to identify critical windows of exposure for children's health: Immune and respiratory systems work group summary
    • Dietert RR, Etzel RA, Chen D, Halonen M, Holladay SD, Jarabek AM, et al. 2000. Workshop to identify critical windows of exposure for children's health: immune and respiratory systems work group summary. Environ Health Perspect 108:483-490.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 483-490
    • Dietert, R.R.1    Etzel, R.A.2    Chen, D.3    Halonen, M.4    Holladay, S.D.5    Jarabek, A.M.6
  • 15
    • 0034993738 scopus 로고    scopus 로고
    • Uncertainty factors for chemical risk assessment: Human variability in the pharmacokinetics of CYP1A2 probe substrates
    • Dorne JLCM, Walton K, Renwick AG. 2001. Uncertainty factors for chemical risk assessment: human variability in the pharmacokinetics of CYP1A2 probe substrates. Food Chem Toxicol 39:681-696.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 681-696
    • Dorne, J.L.C.M.1    Walton, K.2    Renwick, A.G.3
  • 20
    • 0030908438 scopus 로고    scopus 로고
    • The effects of maternal cigarette smoke exposure on somatic mutant frequencies at the hprt locus in healthy newborns
    • Finette BA, Poseno T, Vacek PM, Albertini RJ. 1997. The effects of maternal cigarette smoke exposure on somatic mutant frequencies at the hprt locus in healthy newborns. Mutat Res 377:115-123.
    • (1997) Mutat. Res. , vol.377 , pp. 115-123
    • Finette, B.A.1    Poseno, T.2    Vacek, P.M.3    Albertini, R.J.4
  • 22
    • 0036978894 scopus 로고    scopus 로고
    • Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration
    • Gentry PR, Covington TR, Anderson ME, Clewell HJ III. 2002. Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration. Regul Toxicol Pharmacol 36:51-68.
    • (2002) Regul. Toxicol. Pharmacol. , vol.36 , pp. 51-68
    • Gentry, P.R.1    Covington, T.R.2    Anderson, M.E.3    Clewell III, H.J.4
  • 23
    • 0031454073 scopus 로고    scopus 로고
    • Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high dose busulfan
    • Gibbs JP, Murray G, Risler L, Chien JY, Dev R, Slattery JT. 1997. Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high dose busulfan. Cancer Res 57:5509-5516.
    • (1997) Cancer Res. , vol.57 , pp. 5509-5516
    • Gibbs, J.P.1    Murray, G.2    Risler, L.3    Chien, J.Y.4    Dev, R.5    Slattery, J.T.6
  • 25
    • 0036211903 scopus 로고    scopus 로고
    • Evaluation of child/adult pharmacokinetic differences from a database derived from the therapeutic drug literature
    • Ginsberg GL, Hattis D, Sonawane B, Russ A, Banati P, Kozlak M, et al. 2002. Evaluation of child/adult pharmacokinetic differences from a database derived from the therapeutic drug literature. Toxicol Sci 66:185-200.
    • (2002) Toxicol. Sci. , vol.66 , pp. 185-200
    • Ginsberg, G.L.1    Hattis, D.2    Sonawane, B.3    Russ, A.4    Banati, P.5    Kozlak, M.6
  • 26
    • 0242664617 scopus 로고    scopus 로고
    • Physiological modeling to characterize adult-children differences in pharmacokinetics
    • Abstract # 657
    • Haddad S, Restieri C, Krishnan K. 1999. Physiological modeling to characterize adult-children differences in pharmacokinetics. Abstract # 657. Toxicologist 48:140.
    • (1999) Toxicologist , vol.48 , pp. 140
    • Haddad, S.1    Restieri, C.2    Krishnan, K.3
  • 27
    • 0028888384 scopus 로고
    • Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins
    • Hashimoto H, Nakagawa T, Yokoi T, Sawada M, Itoh S, Kamataki T. 1995. Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins. Cancer Res 55:787-791.
    • (1995) Cancer Res. , vol.55 , pp. 787-791
    • Hashimoto, H.1    Nakagawa, T.2    Yokoi, T.3    Sawada, M.4    Itoh, S.5    Kamataki, T.6
  • 28
    • 0031213798 scopus 로고    scopus 로고
    • In vivo the environmental pollutants lead and mercury induce oligo T cell responses skewed toward type-2 reactivities
    • Heo Y, Lee WT, Lawrence DA. 1997. In vivo the environmental pollutants lead and mercury induce oligo T cell responses skewed toward type-2 reactivities. Cell Immunol 179:185-195.
    • (1997) Cell Immunol. , vol.179 , pp. 185-195
    • Heo, Y.1    Lee, W.T.2    Lawrence, D.A.3
  • 29
    • 0036156595 scopus 로고    scopus 로고
    • The ontogeny of human drug metabolizing enzymes: Phase I oxidative enzymes
    • Hines RN, McCarver DG. 2002. The ontogeny of human drug metabolizing enzymes: phase I oxidative enzymes. J Pharmacol Exp Ther 300:355-360.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 355-360
    • Hines, R.N.1    McCarver, D.G.2
  • 30
    • 0033941252 scopus 로고    scopus 로고
    • Development of the murine and human immune system: Differential effects of immunotoxicants depend on time of exposure
    • Holladay SD, Smialowicz RJ. 2000. Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure. Environ Health Perspect 108:463-473.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 463-473
    • Holladay, S.D.1    Smialowicz, R.J.2
  • 31
    • 0011773729 scopus 로고    scopus 로고
    • Research Needs on Age-Related Differences in Susceptibility to Chemical Toxicants
    • ILSI RSI Report prepared by an ILSI RSI working group. Washington, DC:International Life Sciences Institute Risk Science Institute
    • ILSI RSI. 1996. Research Needs on Age-Related Differences in Susceptibility to Chemical Toxicants. Report prepared by an ILSI RSI working group. Washington, DC:International Life Sciences Institute Risk Science Institute.
    • (1996)
  • 33
    • 1042299444 scopus 로고    scopus 로고
    • Appendix A: Origin and framework of the development of dietary reference intakes
    • IOM (Institute of Medicine). Washington, DC:National Academy Press
    • IOM (Institute of Medicine). 2001. Appendix A: Origin and framework of the development of dietary reference intakes. In: Dietary Reference Intakes: Applications in Dietary Assessment. Washington, DC:National Academy Press, 179-184.
    • (2001) Dietary Reference Intakes: Applications in Dietary Assessment , pp. 179-184
  • 34
    • 0018820632 scopus 로고
    • Drug biotransformation in the placenta
    • Juchau MR. 1980. Drug biotransformation in the placenta. Pharmacol Ther 8:501-524.
    • (1980) Pharmacol. Ther. , vol.8 , pp. 501-524
    • Juchau, M.R.1
  • 35
    • 0032589771 scopus 로고    scopus 로고
    • Effect of plasma alpha1-acid glycoprotein concentration on the accumulation of lidocaine metabolites during continuous epidural anaesthesia in infants and children
    • Kakiuchi Y, Kohda Y, Miyabe M, Momose Y. 1999. Effect of plasma alpha1-acid glycoprotein concentration on the accumulation of lidocaine metabolites during continuous epidural anaesthesia in infants and children. Int J Clin Pharmacol Ther 37:493-498.
    • (1999) Int. J. Clin. Pharmacol. Ther. , vol.37 , pp. 493-498
    • Kakiuchi, Y.1    Kohda, Y.2    Miyabe, M.3    Momose, Y.4
  • 36
    • 0030670353 scopus 로고    scopus 로고
    • Extrapolation of in vitro enzyme induction data to humans in vivo
    • Kedderis GL. 1997. Extrapolation of in vitro enzyme induction data to humans in vivo. Chem Biol Interact 107:109-121.
    • (1997) Chem. Biol. Interact. , vol.107 , pp. 109-121
    • Kedderis, G.L.1
  • 37
    • 1042287744 scopus 로고    scopus 로고
    • Improving risk assessment for human developmental defects: The promise of recent advances in developmental biology and genomics
    • Using Mechanistic Data from Developmental and Molecular Biology for Developmental Toxicity Risk Assessment. Continuing Education Course #16. Society of Toxicology 40th Annual Meeting, 25-29 March 2001, San Francisco, California
    • Kimmel CA. 2001. Improving risk assessment for human developmental defects: the promise of recent advances in developmental biology and genomics. In: Using Mechanistic Data from Developmental and Molecular Biology for Developmental Toxicity Risk Assessment. Continuing Education Course #16. Society of Toxicology 40th Annual Meeting, 25-29 March 2001, San Francisco, California. Toxicologist 60(suppl):3.
    • (2001) Toxicologist , vol.60 , Issue.SUPPL. , pp. 3
    • Kimmel, C.A.1
  • 40
    • 1042287740 scopus 로고    scopus 로고
    • Physiological pharmacokinetic models in the risk assessment of developmental neurotoxicants
    • (Slikker W, Chang L, eds). New York:Academic Press
    • Krishnan K, Andersen ME. 1998. Physiological pharmacokinetic models in the risk assessment of developmental neurotoxicants. In: Handbook of Developmental Neurotoxicity (Slikker W, Chang L, eds). New York:Academic Press, 709-725.
    • (1998) Handbook of Developmental Neurotoxicity , pp. 709-725
    • Krishnan, K.1    Andersen, M.E.2
  • 41
    • 1042280395 scopus 로고    scopus 로고
    • Children's health and the environment: Public health issues and challenges for risk assessment
    • Landrigan PJ, Kimmel CA, Correa A, Eskenazi B. 2004. Children's health and the environment: public health issues and challenges for risk assessment. Environ Health Perspect 112:257-265.
    • (2004) Environ. Health Perspect. , vol.112 , pp. 257-265
    • Landrigan, P.J.1    Kimmel, C.A.2    Correa, A.3    Eskenazi, B.4
  • 42
    • 0035793133 scopus 로고    scopus 로고
    • Developmental windows of differential lead-induced immunotoxicity in chickens
    • Lee JE, Chen S, Golemboski KA, Parsons PJ, Dietert RR. 2001. Developmental windows of differential lead-induced immunotoxicity in chickens. Toxicology 156:161-170.
    • (2001) Toxicology , vol.156 , pp. 161-170
    • Lee, J.E.1    Chen, S.2    Golemboski, K.A.3    Parsons, P.J.4    Dietert, R.R.5
  • 43
    • 0343627009 scopus 로고    scopus 로고
    • Workshop to identify critical windows of exposure for children's health: Reproductive health in children and adolescents work group summary
    • Lemasters GK, Perreault SD, Hales BF, Hatch M, Hirshfield AN, Hughes CL, et al. 2000. Workshop to identify critical windows of exposure for children's health: reproductive health in children and adolescents work group summary. Environ Health Perspect 108:505-509.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 505-509
    • Lemasters, G.K.1    Perreault, S.D.2    Hales, B.F.3    Hatch, M.4    Hirshfield, A.N.5    Hughes, C.L.6
  • 44
    • 1042299441 scopus 로고    scopus 로고
    • Biomarkers for child's health: Developing biologically based risk assessment models for linking exposure and health effects
    • Poster presented at International Society of Exposure Analysis (ISEA), International Society for Environmental Epidemiology (ISEE), August 2002, Vancouver, BC, Canada
    • Lewandowski TA, Hoeft JA, Bartell SM, Wong EY, Griffith WC, Faustman EM. 2002. Biomarkers for child's health: developing biologically based risk assessment models for linking exposure and health effects. Poster presented at International Society of Exposure Analysis (ISEA), International Society for Environmental Epidemiology (ISEE), August 2002, Vancouver, BC, Canada.
    • (2002)
    • Lewandowski, T.A.1    Hoeft, J.A.2    Bartell, S.M.3    Wong, E.Y.4    Griffith, W.C.5    Faustman, E.M.6
  • 47
    • 0345476864 scopus 로고    scopus 로고
    • Lead intoxication impairs the generation of a delayed hypersensitivity response
    • McCabe MJ Jr, Singh KP, Rainers JJ Jr. 1999. Lead intoxication impairs the generation of a delayed hypersensitivity response. Toxicology 139:255-264.
    • (1999) Toxicology , vol.139 , pp. 255-264
    • McCabe Jr., M.J.1    Singh, K.P.2    Rainers Jr., J.J.3
  • 48
    • 0036151643 scopus 로고    scopus 로고
    • The ontogeny of human drug metabolizing enzymes: Phase II conjugation enzymes and regulatory mechanisms
    • McCarver DG, Hines RN. 2002. The ontogeny of human drug metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms. J Pharmacol Exp Ther 300: 361-366.
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 361-366
    • McCarver, D.G.1    Hines, R.N.2
  • 49
    • 0001864615 scopus 로고
    • Comparative responses in carcinogenesis bioassays as a function of age at first exposure
    • (Guzelian PS, Henry CJ, Olin SS, eds). Washington, DC:ILSI Press
    • McConnell EE. 1992. Comparative responses in carcinogenesis bioassays as a function of age at first exposure. In: Similarities and Differences between Children and Adults: Implications for Risk Assessment (Guzelian PS, Henry CJ, Olin SS, eds). Washington, DC:ILSI Press, 66-78.
    • (1992) Similarities and Differences Between Children and Adults: Implications for Risk Assessment , pp. 66-78
    • McConnell, E.E.1
  • 50
    • 0025194293 scopus 로고
    • The formation of 3-methylcholanthrene-initiated lung tumors correlate with induction of cytochrome P4501A1 by the carcinogen in fetal but not adult mice
    • Miller MS, Jones AB, Park SS, Anderson LM. 1990. The formation of 3-methylcholanthrene-initiated lung tumors correlate with induction of cytochrome P4501A1 by the carcinogen in fetal but not adult mice. Toxicol Appl Pharmacol 104:235-245.
    • (1990) Toxicol. Appl. Pharmacol , vol.104 , pp. 235-245
    • Miller, M.S.1    Jones, A.B.2    Park, S.S.3    Anderson, L.M.4
  • 52
    • 0036715352 scopus 로고    scopus 로고
    • Using the new dietary reference intakes to assess diets: A map to the maze
    • Murphy SP, Barr SI, Poos MI. 2002. Using the new dietary reference intakes to assess diets: a map to the maze. Nutr Rev 60:267-275.
    • (2002) Nutr. Rev. , vol.60 , pp. 267-275
    • Murphy, S.P.1    Barr, S.I.2    Poos, M.I.3
  • 55
    • 0141740530 scopus 로고    scopus 로고
    • Workshop to develop a framework for assessing risks to children from exposure to environmental agents
    • Olin SS, Sonawane BR. 2003. Workshop to develop a framework for assessing risks to children from exposure to environmental agents. Environ Health Perspect 111:1524-1526.
    • (2003) Environ. Health Perspect. , vol.111 , pp. 1524-1526
    • Olin, S.S.1    Sonawane, B.R.2
  • 56
    • 0033910525 scopus 로고    scopus 로고
    • Workshop to identify critical windows of exposure for children's health: Cancer work group summary
    • Olshan AF, Anderson L, Roman E, Fear N, Wolff M, Whyatt R, et al. 2000. Workshop to identify critical windows of exposure for children's health: cancer work group summary. Environ Health Perspect 108:595-597.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 595-597
    • Olshan, A.F.1    Anderson, L.2    Roman, E.3    Fear, N.4    Wolff, M.5    Whyatt, R.6
  • 58
    • 0023771711 scopus 로고
    • Quantitation of complex brain function in children: Preliminary evaluation using a nonhuman primate behavioral test battery
    • Paule MG, Cranmer JM, Wilkins JD, Stern HP, Hoffman EL. 1988. Quantitation of complex brain function in children: preliminary evaluation using a nonhuman primate behavioral test battery. Neurotoxicology 9:367-378.
    • (1988) Neurotoxicology , vol.9 , pp. 367-378
    • Paule, M.G.1    Cranmer, J.M.2    Wilkins, J.D.3    Stern, H.P.4    Hoffman, E.L.5
  • 59
    • 0033200203 scopus 로고    scopus 로고
    • Symposium overview the use of timing behaviors in animals and humans to detect drug and/or toxicant effects
    • Paule MG, Meck WH, McMillan DE, McClure GY, Bateson M, Popke EJ, et al. 1999b. Symposium overview the use of timing behaviors in animals and humans to detect drug and/or toxicant effects. Neurotoxicol Teratol 21:491-502.
    • (1999) Neurotoxicol. Teratol. , vol.21 , pp. 491-502
    • Paule, M.G.1    Meck, W.H.2    McMillan, D.E.3    McClure, G.Y.4    Bateson, M.5    Popke, E.J.6
  • 60
    • 0035085431 scopus 로고    scopus 로고
    • Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds
    • Pelekis M, Gephart LA, Lerman SE. 2001. Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds. Regul Toxicol Pharmacol 33:12-20.
    • (2001) Regul. Toxicol. Pharmacol. , vol.33 , pp. 12-20
    • Pelekis, M.1    Gephart, L.A.2    Lerman, S.E.3
  • 61
    • 0033939622 scopus 로고    scopus 로고
    • The mammalian respiratory system and critical windows of exposure for children's health
    • Pinkerton KE, Joad JP. 2000. The mammalian respiratory system and critical windows of exposure for children's health. Environ Health Perspect 108:457-462.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 457-462
    • Pinkerton, K.E.1    Joad, J.P.2
  • 63
    • 0033910450 scopus 로고    scopus 로고
    • Critical windows of exposure for children's health: The reproductive system in animals and humans
    • Pryor JL, Hughes C, Foster W, Hales BF, Robaire B. 2000. Critical windows of exposure for children's health: the reproductive system in animals and humans. Environ Health Perspect 108:491-503.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 491-503
    • Pryor, J.L.1    Hughes, C.2    Foster, W.3    Hales, B.F.4    Robaire, B.5
  • 64
    • 0031934439 scopus 로고    scopus 로고
    • Toxicokinetics in infants and children in relation to the ADI and TDI
    • Renwick AG. 1998. Toxicokinetics in infants and children in relation to the ADI and TDI. Food Addit Contam 15(suppl):S17-S35.
    • (1998) Food Addit. Contam. , vol.15 , Issue.SUPPL.
    • Renwick, A.G.1
  • 65
    • 0033883623 scopus 로고    scopus 로고
    • An analysis of the need for an additional uncertainty factor for infants and children
    • Renwick AG, Dorne JL, Walton K. 2000. An analysis of the need for an additional uncertainty factor for infants and children. Regul Toxicol Pharmacol 31:286-296.
    • (2000) Regul. Toxicol. Pharmacol. , vol.31 , pp. 286-296
    • Renwick, A.G.1    Dorne, J.L.2    Walton, K.3
  • 66
    • 0033911258 scopus 로고    scopus 로고
    • Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models
    • Rice D, Barone S Jr. 2000. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 108:511-533.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 511-533
    • Rice, D.1    Barone Jr., S.2
  • 67
    • 0024326309 scopus 로고
    • Comparative transplacental carcinogenesis by directly acting and metabolism-dependent alkylating agents in rodents and nonhuman primates
    • Rice JM, Rehm S, Donovan PJ, Perantoni AO. 1989. Comparative transplacental carcinogenesis by directly acting and metabolism-dependent alkylating agents in rodents and nonhuman primates. IARC Sci Publ 96:17-34.
    • (1989) IARC Sci. Publ. , vol.96 , pp. 17-34
    • Rice, J.M.1    Rehm, S.2    Donovan, P.J.3    Perantoni, A.O.4
  • 68
    • 0017691471 scopus 로고
    • Correlations between prenatally-induced alterations in CNS cell populations and postnatal function
    • Rodier PM. 1977. Correlations between prenatally-induced alterations in CNS cell populations and postnatal function. Teratology 16:235-246.
    • (1977) Teratology , vol.16 , pp. 235-246
    • Rodier, P.M.1
  • 69
    • 0023904260 scopus 로고
    • Acute effects of delta-9-tetrahydrocannabinol (THC) in rhesus monkeys as measured by performance in a battery of cognitive function tests
    • Schulze GE, McMillan DE, Bailey JR, Scallet A, Ali SF, Slikker W Jr, et al. 1988. Acute effects of delta-9-tetrahydrocannabinol (THC) in rhesus monkeys as measured by performance in a battery of cognitive function tests. J Pharmacol Exp Ther 245:178-186.
    • (1988) J. Pharmacol. Exp. Ther. , vol.245 , pp. 178-186
    • Schulze, G.E.1    McMillan, D.E.2    Bailey, J.R.3    Scallet, A.4    Ali, S.F.5    Slikker Jr., W.6
  • 70
    • 0033927508 scopus 로고    scopus 로고
    • Identifying critical windows of exposure for children's health
    • Selevan SG, Kimmel CA, Mendola P. 2000. Identifying critical windows of exposure for children's health. Environ Health Perspect 108:451-455.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 451-455
    • Selevan, S.G.1    Kimmel, C.A.2    Mendola, P.3
  • 72
    • 0020072213 scopus 로고
    • Comparison of the transplacental pharmacokinetics of 17β-estradiol and diethylstilbestrol in the subhuman primate
    • Slikker W, Hill DE, Young JF. 1982. Comparison of the transplacental pharmacokinetics of 17β-estradiol and diethylstilbestrol in the subhuman primate. J Pharmacol Exp Ther 221:173-182.
    • (1982) J. Pharmacol. Exp. Ther. , vol.221 , pp. 173-182
    • Slikker, W.1    Hill, D.E.2    Young, J.F.3
  • 73
    • 0031956103 scopus 로고    scopus 로고
    • Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits
    • Smiley-Jewell SM, Nishio SJ, Weir AJ, Plopper CG. 1998. Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits. Am J Physiol 274(4 pt 1): L485-L498.
    • (1998) Am. J. Physiol. , vol.274 , Issue.4 PART 1
    • Smiley-Jewell, S.M.1    Nishio, S.J.2    Weir, A.J.3    Plopper, C.G.4
  • 74
    • 0023338067 scopus 로고
    • Determinants of bile formation during development: Ontogeny of hepatic bile acid metabolism and transport
    • Suchy FJ, Bucuvalas JC, Novak DA. 1987. Determinants of bile formation during development: ontogeny of hepatic bile acid metabolism and transport. Semin Liver Dis 7:77-84.
    • (1987) Semin. Liver Dis. , vol.7 , pp. 77-84
    • Suchy, F.J.1    Bucuvalas, J.C.2    Novak, D.A.3
  • 75
    • 0003417276 scopus 로고
    • Dermal Exposure Assessment: Principles and Applications
    • U.S. EPA. EPA/600/8-91/011B. Washington, DC:U.S. Environmental Protection Agency. Available: [accessed 15 May 2003]
    • U.S. EPA. 1992. Dermal Exposure Assessment: Principles and Applications. EPA/600/8-91/011B. Washington, DC:U.S. Environmental Protection Agency. Available: http://epa.gov/osp/spc/cumrisk2.htm [accessed 15 May 2003].
    • (1992)
  • 76
    • 0003536223 scopus 로고
    • Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry
    • U.S. EPA. EPA/600/8-90/066F. Washington, DC:U.S. Environmental Protection Agency
    • U.S. EPA. 1994. Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry. EPA/600/8-90/066F. Washington, DC:U.S. Environmental Protection Agency.
    • (1994)
  • 77
    • 1042264684 scopus 로고
    • Policy on Evaluating Health Risks to Children
    • U.S. EPA. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: [accessed 2 December 2002]
    • U.S. EPA. 1995a. Policy on Evaluating Health Risks to Children. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: http://www.epa.gov/osp/spc/memohlth.htm [accessed 2 December 2002].
    • (1995)
  • 78
    • 0344759560 scopus 로고
    • Policy for Risk Characterization at the U.S. Environmental Protection Agency
    • U.S. EPA. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: [accessed 2 December 2002]
    • U.S. EPA. 1995b. Policy for Risk Characterization at the U.S. Environmental Protection Agency. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: http://www.epa.gov/osp/spc/rcpolicy.htm [accessed 2 December 2002].
    • (1995)
  • 79
    • 0005000022 scopus 로고    scopus 로고
    • Guidance on Cumulative Risk Assessment. Part 1: Planning and Scoping
    • U.S. EPA. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: [accessed 18 December 2003]
    • U.S. EPA. 1997. Guidance on Cumulative Risk Assessment. Part 1: Planning and Scoping. Washington, DC:Science Policy Council, U.S. Environmental Protection Agency. Available: http://www.epa.gov/osp/spc/cumrisk2.htm [accessed 18 December 2003].
    • (1997)
  • 80
    • 0003662518 scopus 로고    scopus 로고
    • U.S. EPA. Draft, July. NCEA-F-0644 Washington, DC:U.S. Environmental Protection Agency
    • U.S. EPA. 1999. Guidelines for Carcinogen Risk Assessment. Draft, July. NCEA-F-0644. Washington, DC:U.S. Environmental Protection Agency.
    • (1999) Guidelines for Carcinogen Risk Assessment
  • 81
    • 0003432398 scopus 로고    scopus 로고
    • U.S. EPA. NCEA-W-0853. 01 Jun 2000. Washington, DC:U.S. Environmental Protection Agency. Available: [accessed 6 December 2002]
    • U.S. EPA. 2000. Child-Specific Exposure Factors Handbook. NCEA-W-0853. 01 Jun 2000. Washington, DC:U.S. Environmental Protection Agency. Available: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=17880 [accessed 6 December 2002].
    • (2000) Child-Specific Exposure Factors Handbook
  • 82
    • 0012627845 scopus 로고    scopus 로고
    • The Grouping of a Series of Triazine Pesticides Based on a Common Mechanism of Toxicity
    • U.S. EPA. Washington, DC:Office of Pesticide Programs. Available: [accessed 6 December 2002]
    • U.S. EPA. 2002. The Grouping of a Series of Triazine Pesticides Based on a Common Mechanism of Toxicity. Washington, DC:Office of Pesticide Programs. Available: http://www.epa.gov/oppsrrd1/cumulative/triazines/triazinescommonmech.pdf [accessed 6 December 2002].
    • (2002)
  • 83
    • 0003526130 scopus 로고
    • Framework for Ecological Risk Assessment
    • U.S. EPA Risk Assessment Forum. EPA/630/R-92/001. Washington, DC:U.S. Environmental Protection Agency Available: [accessed 6 December 2000]
    • U.S. EPA Risk Assessment Forum. 1992. Framework for Ecological Risk Assessment. EPA/630/R-92/001. Washington, DC:U.S. Environmental Protection Agency Available: http://cfpub.epa.gov/ncea/raf/rafrprts.cfm [accessed 6 December 2000].
    • (1992)
  • 84
    • 1042299442 scopus 로고    scopus 로고
    • U.S. EPA Risk Assessment Forum. Summary Report of the Technical Workshop on Issues Associated with Considering Developmental Changes in Behavior and Anatomy When Assessing Exposure to Children EPA/630/R-00/005. Washington, DC:U.S. Environmental Protection Agency. Available: [accessed 2 December 2002]
    • U.S. EPA Risk Assessment Forum. 2000. Summary Report of the Technical Workshop on Issues Associated with Considering Developmental Changes in Behavior and Anatomy When Assessing Exposure to Children. EPA/630/R-00/005. Washington, DC:U.S. Environmental Protection Agency. Available: http://www.epa.gov/ncea/raf/workshops.htm [accessed 2 December 2002].
    • (2000)
  • 85
    • 0033926801 scopus 로고    scopus 로고
    • Vulnerability of children and the developing brain to neurotoxic hazards
    • Weiss B. 2000. Vulnerability of children and the developing brain to neurotoxic hazards. Environ Health Perspect 108:375-381.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 375-381
    • Weiss, B.1
  • 86
    • 1042299443 scopus 로고
    • Predictability of in vitro diffusion systems. Effect of skin types and ages on percutaneous absorption of trichlorban
    • (Bronaugh RL, Maibach HI, eds). New York:Marcel Dekker
    • Wester RC, Maibach HI, Surinchak J, Bucks DAW. 1985. Predictability of in vitro diffusion systems. Effect of skin types and ages on percutaneous absorption of trichlorban. In: Percutaneous Absorption (Bronaugh RL, Maibach HI, eds). New York:Marcel Dekker, 223-226.
    • (1985) Percutaneous Absorption , pp. 223-226
    • Wester, R.C.1    Maibach, H.I.2    Surinchak, J.3    Bucks, D.A.W.4
  • 87


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