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Volumn 32, Issue 4, 2003, Pages 329-343

Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; ADENOSINE TRIPHOSPHATE; ALPHA SYNUCLEIN; CELL NUCLEUS DNA; CYTOCHROME C; DNA FRAGMENT; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROPROTECTIVE AGENT; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; SELEGILINE; SUPEROXIDE DISMUTASE;

EID: 1042279466     PISSN: 03004864     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NEUR.0000011327.23739.1b     Document Type: Article
Times cited : (69)

References (68)
  • 1
    • 0017744843 scopus 로고
    • The use of PIPES buffer in the fixation of mammalian and marine tissues for electron microscopy
    • BAUR, P. S. & STACEY, T. R. (1977) The use of PIPES buffer in the fixation of mammalian and marine tissues for electron microscopy. Journal of Microscopy 109, 315-327.
    • (1977) Journal of Microscopy , vol.109 , pp. 315-327
    • Baur, P.S.1    Stacey, T.R.2
  • 2
    • 0037029132 scopus 로고    scopus 로고
    • Mitochondrial DNA repair of oxidative damage in mammalian cells
    • BOHR, V. A., STEVNSNER, T. & DE SOUZA-PINTO, N. C. (2002) Mitochondrial DNA repair of oxidative damage in mammalian cells. Gene 286, 127-134.
    • (2002) Gene , vol.286 , pp. 127-134
    • Bohr, V.A.1    Stevnsner, T.2    De Souza-Pinto, N.C.3
  • 4
    • 0028943869 scopus 로고
    • (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush
    • BUYS, Y. M., TROPE, G. E. & TATTON, W. G. (1995) (-)-Deprenyl increases the survival of rat retinal ganglion cells after optic nerve crush. Current Eye Research 14, 119-126.
    • (1995) Current Eye Research , vol.14 , pp. 119-126
    • Buys, Y.M.1    Trope, G.E.2    Tatton, W.G.3
  • 5
    • 0033989493 scopus 로고    scopus 로고
    • Reduced apoptosis after nerve growth factor and serum withdrawal: Conversion of tetrameric glyceraldehyde-3-phosphate dehydrogenase to a dimer
    • CARLILE, G. W., CHALMERS-REDMAN, R. M., TATTON, N. A., PONG, A., BORDEN, K. E. & TATTON, W. G. (2001) Reduced apoptosis after nerve growth factor and serum withdrawal: Conversion of tetrameric glyceraldehyde-3-phosphate dehydrogenase to a dimer. Molecular Pharmacology 57, 2-12.
    • (2001) Molecular Pharmacology , vol.57 , pp. 2-12
    • Carlile, G.W.1    Chalmers-Redman, R.M.2    Tatton, N.A.3    Pong, A.4    Borden, K.E.5    Tatton, W.G.6
  • 6
    • 0019791435 scopus 로고
    • Native banded collagen fibrils in the glomerular mesengial matrix of normal human and laboratory animals
    • CARLSON, E. C. & HINDS, D. (1981) Native banded collagen fibrils in the glomerular mesengial matrix of normal human and laboratory animals. Journal of Ultrastructural Research 77, 241-247.
    • (1981) Journal of Ultrastructural Research , vol.77 , pp. 241-247
    • Carlson, E.C.1    Hinds, D.2
  • 7
    • 0032951125 scopus 로고    scopus 로고
    • + opens the mitochondrial permeability transition pore and releases cytochrome C in isolated mitochondria via an oxidative mechanism
    • + opens the mitochondrial permeability transition pore and releases cytochrome C in isolated mitochondria via an oxidative mechanism. Biochimica Biophysica Acta 1453, 49-62.
    • (1999) Biochimica Biophysica Acta , vol.1453 , pp. 49-62
    • Cassarino, D.S.1    Parks, J.K.2    Parker Jr., W.D.3    Bennett Jr., J.P.4
  • 9
    • 0001791896 scopus 로고    scopus 로고
    • Therapeutic potential of Selegiline in Parkinson's disease and other neurological disorder
    • edited by Marwah, J. & Teitelbaum, H. Prominent Press
    • EBADI, M. (1998) Therapeutic potential of Selegiline in Parkinson's disease and other neurological disorder. In Recent Advances in Neurodegenerative Disorders (edited by MARWAH, J. & TEITELBAUM, H.) pp. 256-350. Prominent Press.
    • (1998) Recent Advances in Neurodegenerative Disorders , pp. 256-350
    • Ebadi, M.1
  • 10
    • 0002136697 scopus 로고    scopus 로고
    • Glutathione and metallothionein in oxidative stress of Parkinson's disease
    • edited by Poli, G., Cadenas, E. & Packer, L. Marcel Dekker, Inc.
    • EBADI, M. & HIRAMATSU, M. (2000) Glutathione and metallothionein in oxidative stress of Parkinson's disease. In Free Radicals in Brain Pathophysiology (edited by POLI, G., CADENAS, E. & PACKER, L.) pp. 427-465. Marcel Dekker, Inc.
    • (2000) Free Radicals in Brain Pathophysiology , pp. 427-465
    • Ebadi, M.1    Hiramatsu, M.2
  • 11
    • 0037561232 scopus 로고    scopus 로고
    • Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease
    • EBADI, M. & SHARMA, S. K. (2003) Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease. Antioxidants and Redox Signaling 5, 319-335.
    • (2003) Antioxidants and Redox Signaling , vol.5 , pp. 319-335
    • Ebadi, M.1    Sharma, S.K.2
  • 19
    • 0035087869 scopus 로고    scopus 로고
    • Eldepryl prevents 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice
    • GUO, M., CHEN, S., LIU, Z. & CHEN, H. (2001) Eldepryl prevents 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice. Chinese Medical Journal 114, 240-243.
    • (2001) Chinese Medical Journal , vol.114 , pp. 240-243
    • Guo, M.1    Chen, S.2    Liu, Z.3    Chen, H.4
  • 20
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • HALLIWELL, B. (2001) Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment. Drugs & Aging 18, 685-716.
    • (2001) Drugs & Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 22
    • 0032879452 scopus 로고    scopus 로고
    • Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease
    • HASHIMOTO, M., TAKEDA, A., HSU, L. J., TAKENOUCHI, T. & MASLIAH, E. (1999) Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease. Journal of Biological Chemistry 274, 28849-28852.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 28849-28852
    • Hashimoto, M.1    Takeda, A.2    Hsu, L.J.3    Takenouchi, T.4    Masliah, E.5
  • 23
    • 0037237927 scopus 로고    scopus 로고
    • Oxidative stress and nitration in neurodegeneration: Cause, effect, or association
    • ISCHIROPOULOS, H. & BECKMAN, J. S. (2003) Oxidative stress and nitration in neurodegeneration: Cause, effect, or association. Journal of Clinical Investigation 111, 163-169.
    • (2003) Journal of Clinical Investigation , vol.111 , pp. 163-169
    • Ischiropoulos, H.1    Beckman, J.S.2
  • 24
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • JENNER, P. & OLANOW, C. W. (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47, S161-S170.
    • (1996) Neurology , vol.47
    • Jenner, P.1    Olanow, C.W.2
  • 25
    • 0035815285 scopus 로고    scopus 로고
    • Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole
    • KAKIMURA, J., KITAMURA, Y., TAKEDA, K., KOHNO, Y., NOMURA, Y. & TANIGUCHI, T. (2001) Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole. European Journal of Pharmacology 417, 59-67.
    • (2001) European Journal of Pharmacology , vol.417 , pp. 59-67
    • Kakimura, J.1    Kitamura, Y.2    Takeda, K.3    Kohno, Y.4    Nomura, Y.5    Taniguchi, T.6
  • 26
    • 0031105902 scopus 로고    scopus 로고
    • Neuroprotective therapy for Parkinson's disease
    • KOLLER, W. C. (1997) Neuroprotective therapy for Parkinson's disease. Experimental Neurology 144, 24-28.
    • (1997) Experimental Neurology , vol.144 , pp. 24-28
    • Koller, W.C.1
  • 28
    • 0030891039 scopus 로고    scopus 로고
    • (-)-Deprenyl protection of 1-methyl-4 phenylpyridium ion (MPP+)-induced apoptosis independent of MAO-B inhibition
    • LEE, W., JANKOVIC, J., XIE, W., KONG, R. & APPEL, S. H. (1997) (-)-Deprenyl protection of 1-methyl-4 phenylpyridium ion (MPP+)-induced apoptosis independent of MAO-B inhibition. Neuroscience Letters 224, 197-200.
    • (1997) Neuroscience Letters , vol.224 , pp. 197-200
    • Lee, W.1    Jankovic, J.2    Xie, W.3    Kong, R.4    Appel, S.H.5
  • 29
    • 0036203428 scopus 로고    scopus 로고
    • Effect of R(-)-deprenyl and harmaline on dopamine and peroxynitrite-induced membrane permeability transition in brain mitochondria
    • LEE, C., KO, H., SONG, J., & HAN, E. (2002) Effect of R(-)-deprenyl and harmaline on dopamine and peroxynitrite-induced membrane permeability transition in brain mitochondria. Neurochemical Research 27, 215-224.
    • (2002) Neurochemical Research , vol.27 , pp. 215-224
    • Lee, C.1    Ko, H.2    Song, J.3    Han, E.4
  • 30
    • 0036127407 scopus 로고    scopus 로고
    • Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death
    • LESUISSE, C. & MARTIN, L. J. (2002) Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death. Journal of Neurobiology 51, 9-23.
    • (2002) Journal of Neurobiology , vol.51 , pp. 9-23
    • Lesuisse, C.1    Martin, L.J.2
  • 32
    • 0034525891 scopus 로고    scopus 로고
    • Neurotoxins induce apoptosis in dopaminergic neurons: Protection by N-propargylamine-1 (R)-and (S)-aminoindan, rasagiline and TV1022
    • MARUYAMA, W., AKAO, Y., YOUDIM, M. & NAOI, M (2000) Neurotoxins induce apoptosis in dopaminergic neurons: Protection by N-propargylamine-1 (R)-and (S)-aminoindan, rasagiline and TV1022. Journal of Neural Transmission 60(Suppl), 171-186.
    • (2000) Journal of Neural Transmission , vol.60 , Issue.SUPPL. , pp. 171-186
    • Maruyama, W.1    Akao, Y.2    Youdim, M.3    Naoi, M.4
  • 33
    • 0034928655 scopus 로고    scopus 로고
    • Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl (R) Salsolinol, in dopaminergic SH-SY5Y cells: Suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine
    • MARUYAMA, W., BOULTON, A., DAVIS, B., DOSTERT, P. & NAOI, M. (2001) Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl (R) Salsolinol, in dopaminergic SH-SY5Y cells: Suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine. Journal of Neural Transmission 108, 11-24.
    • (2001) Journal of Neural Transmission , vol.108 , pp. 11-24
    • Maruyama, W.1    Boulton, A.2    Davis, B.3    Dostert, P.4    Naoi, M.5
  • 34
    • 0035917904 scopus 로고    scopus 로고
    • L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: A microdialysis study in rats
    • MATSUBARA, K., SENDA, T., UEZONO, T., AWAYA, T., OGAWA, S., CHIBA, K., SHIMIZU, K., HAYASE, N. & KIMURA, K. (2001) L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: A microdialysis study in rats. Neuroscience Letters 302, 65-68.
    • (2001) Neuroscience Letters , vol.302 , pp. 65-68
    • Matsubara, K.1    Senda, T.2    Uezono, T.3    Awaya, T.4    Ogawa, S.5    Chiba, K.6    Shimizu, K.7    Hayase, N.8    Kimura, K.9
  • 35
    • 0033678294 scopus 로고    scopus 로고
    • Involvement of endogenous N-methyl(R) salsolinol in Parkinson's disease: Induction of apoptosis and protection by (-) deprenyl
    • NAOI, M., MARUYAMA, W., TAKAHASHI, T., AKAO, Y. & NAKAGAWA, Y. (2000a) Involvement of endogenous N-methyl(R) salsolinol in Parkinson's disease: Induction of apoptosis and protection by (-) deprenyl. Journal of Neural Transmission 58(Suppl), 111-121.
    • (2000) Journal of Neural Transmission , vol.58 , Issue.SUPPL. , pp. 111-121
    • Naoi, M.1    Maruyama, W.2    Takahashi, T.3    Akao, Y.4    Nakagawa, Y.5
  • 36
    • 0033812934 scopus 로고    scopus 로고
    • Anti-apoptotic function of L-(-) deprenyl (Selegiline) and related compounds
    • NAOI, M., MARUYAMA, W., YAGI, K. & YOUDIM, M. (2000b) Anti-apoptotic function of L-(-) deprenyl (Selegiline) and related compounds. Neurobiology 8, 69-80.
    • (2000) Neurobiology , vol.8 , pp. 69-80
    • Naoi, M.1    Maruyama, W.2    Yagi, K.3    Youdim, M.4
  • 37
  • 38
    • 0030300166 scopus 로고    scopus 로고
    • Deprenyl in the treatment of Parkinson's disease: Clinical effects and speculations on mechanism of action
    • OLANOW, C. W. (1996) Deprenyl in the treatment of Parkinson's disease: Clinical effects and speculations on mechanism of action. Journal of Neural Transmission 48(Suppl), 75-84.
    • (1996) Journal of Neural Transmission , vol.48 , Issue.SUPPL. , pp. 75-84
    • Olanow, C.W.1
  • 40
    • 0031914155 scopus 로고    scopus 로고
    • R-deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium
    • PATERSON, I. A., ZHANG, D., WARRINGTON, R. C. & BOULTON, A. A. (1998) R-deprenyl and R-2-heptyl-N-methylpropargylamine prevent apoptosis in cerebellar granule neurons induced by cytosine arabinoside but not low extracellular potassium. Journal of Neurochemistry 70, 515-523.
    • (1998) Journal of Neurochemistry , vol.70 , pp. 515-523
    • Paterson, I.A.1    Zhang, D.2    Warrington, R.C.3    Boulton, A.A.4
  • 41
    • 77956767839 scopus 로고    scopus 로고
    • Antiapoptotic actions of monoamine oxidase B inhibitors
    • PATERSON, I. A. & TATTON, W. G. (1998) Antiapoptotic actions of monoamine oxidase B inhibitors. Advances in Pharmacology 42, 312-315.
    • (1998) Advances in Pharmacology , vol.42 , pp. 312-315
    • Paterson, I.A.1    Tatton, W.G.2
  • 42
    • 0032848686 scopus 로고    scopus 로고
    • Multiple antioxidants in the prevention and treatment of Parkinson's disease
    • PRASAD, K. N., COLE, W. C. & KUMAR, B. (1999) Multiple antioxidants in the prevention and treatment of Parkinson's disease. Journal of American College of Nutrition 18, 413-423.
    • (1999) Journal of American College of Nutrition , vol.18 , pp. 413-423
    • Prasad, K.N.1    Cole, W.C.2    Kumar, B.3
  • 44
    • 0036970672 scopus 로고    scopus 로고
    • Deferoxamine attenuates Iron-induced oxidative stress and prevents mitochondrial aggregation and α-synuclein translocation in SK-N-SH cells in culture
    • SANGCHOT, O., SHARMA, S., CHETSAWANG, B., PORTER, J., GOVITROPONG, P. & EBADI, M. (2002) Deferoxamine attenuates Iron-induced oxidative stress and prevents mitochondrial aggregation and α-synuclein translocation in SK-N-SH cells in culture. Devevelopmental Neuroscience 24, 143-153.
    • (2002) Devevelopmental Neuroscience , vol.24 , pp. 143-153
    • Sangchot, O.1    Sharma, S.2    Chetsawang, B.3    Porter, J.4    Govitropong, P.5    Ebadi, M.6
  • 45
    • 0033840581 scopus 로고    scopus 로고
    • MPTP activates c-Jun NH (2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
    • SAPORITO, M. S., THOMAS, B. A. & SCOTT, R. W. (2000) MPTP activates c-Jun NH (2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. Journal of Neurochemistry 75, 1200-1208.
    • (2000) Journal of Neurochemistry , vol.75 , pp. 1200-1208
    • Saporito, M.S.1    Thomas, B.A.2    Scott, R.W.3
  • 47
    • 0038575498 scopus 로고    scopus 로고
    • Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons
    • SHARMA, S. K. & EBADI, M. (2003) Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons. Antioxidants and Redox Signaling 5, 251-264.
    • (2003) Antioxidants and Redox Signaling , vol.5 , pp. 251-264
    • Sharma, S.K.1    Ebadi, M.2
  • 48
    • 0037104723 scopus 로고    scopus 로고
    • An in-vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
    • SHERER, T. B., BETARBET, R., STOUT, A. K., LUND, S., BAPTISTA, M., PANOV, A. V., COOKSON, M. R. & GREENAMYRE, J. T. (2002) An in-vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. Journal of Neuroscience 15, 7006-7015.
    • (2002) Journal of Neuroscience , vol.15 , pp. 7006-7015
    • Sherer, T.B.1    Betarbet, R.2    Stout, A.K.3    Lund, S.4    Baptista, M.5    Panov, A.V.6    Cookson, M.R.7    Greenamyre, J.T.8
  • 49
  • 51
    • 0034231055 scopus 로고    scopus 로고
    • Is there an effective neuroprotective treatment of Parkinson's disease? (therapeutic possibilities against the background of etiopathogenetic concepts)
    • SLAWEK, J. (2000) Is there an effective neuroprotective treatment of Parkinson's disease? (therapeutic possibilities against the background of etiopathogenetic concepts). Neurology Neurochirology (Poland) 34, 733-742.
    • (2000) Neurology Neurochirology (Poland) , vol.34 , pp. 733-742
    • Slawek, J.1
  • 52
    • 0034674652 scopus 로고    scopus 로고
    • Dityrosine cross-linking promotes formation of stable alpha-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
    • SOUZA, K. M., GIASSON, B. I., CHEN, Q., LEE, V. M. & ISCHIROPOULOS, H. (2000) Dityrosine cross-linking promotes formation of stable alpha-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. Journal of Biological Chemistry 275, 18344-18349.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 18344-18349
    • Souza, K.M.1    Giasson, B.I.2    Chen, Q.3    Lee, V.M.4    Ischiropoulos, H.5
  • 54
    • 0034476732 scopus 로고    scopus 로고
    • Apoptotic and antiapoptotic effect of (-)deprenyl and (-)-desmethyl-deprenyl on human cell lines
    • SZENDE, B., MAGYAR, K. & SZEGEDI, Z. (2000) Apoptotic and antiapoptotic effect of (-)deprenyl and (-)-desmethyl-deprenyl on human cell lines. Neurobiology 8, 249-255.
    • (2000) Neurobiology , vol.8 , pp. 249-255
    • Szende, B.1    Magyar, K.2    Szegedi, Z.3
  • 55
    • 0037205095 scopus 로고    scopus 로고
    • Tyrosine 125 of alpha-synuclein plays a critical role for dimerization following nitrative stress
    • TAKAHASHI, T., YAMASHITA, H., NAKAMURA, T., NAGANO, Y. & NAKAMURA, S. (2002) Tyrosine 125 of alpha-synuclein plays a critical role for dimerization following nitrative stress. Brain Research 938, 73-80.
    • (2002) Brain Research , vol.938 , pp. 73-80
    • Takahashi, T.1    Yamashita, H.2    Nakamura, T.3    Nagano, Y.4    Nakamura, S.5
  • 56
    • 0027941312 scopus 로고
    • Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis
    • TATTON, W. G., JU, W. Y., HOLLAND, D. P., TAI, C. & KWAN, M. (1994) (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. Journal of Neurochemistry 63, 1572-1575.
    • (1994) Journal of Neurochemistry , vol.63 , pp. 1572-1575
    • Tatton, W.G.1    Ju, W.Y.2    Holland, D.P.3    Tai, C.4    Kwan, M.5
  • 57
    • 0030300164 scopus 로고    scopus 로고
    • Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase
    • TATTON, W. G., WADIA, J. S., JU, W. Y., CHALMERS-REDMAN, R. M. & TATTON, N. A. (1996) (-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. Journal of Neural Transmission 48(Suppl), 45-59.
    • (1996) Journal of Neural Transmission , vol.48 , Issue.SUPPL. , pp. 45-59
    • Tatton, W.G.1    Wadia, J.S.2    Ju, W.Y.3    Chalmers-Redman, R.M.4    Tatton, N.A.5
  • 58
    • 0029731378 scopus 로고    scopus 로고
    • Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration
    • TATTON, W. G. & CHALMERS-REDMAN, R. M. (1996) Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration. Neurology 47, S171-S183.
    • (1996) Neurology , vol.47
    • Tatton, W.G.1    Chalmers-Redman, R.M.2
  • 60
    • 18744432650 scopus 로고    scopus 로고
    • Antiapoptotic effect of (-)-deprenyl in rat kidney after ischemia-reperfusion
    • TORONYI, E., HAMAR, J., MAGYAR, K. & SZENDE, B. (2002) Antiapoptotic effect of (-)-deprenyl in rat kidney after ischemia-reperfusion. Medical Science Monitoring 8, BR65-BR68.
    • (2002) Medical Science Monitoring , vol.8
    • Toronyi, E.1    Hamar, J.2    Magyar, K.3    Szende, B.4
  • 61
    • 0035798306 scopus 로고    scopus 로고
    • Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice
    • UNAL, I., GURSOY-OZDEMIR, Y., BOLAY, H., SOYLEMEZOGLU, F., SARIBAS, O. & DALKARA, T. (2001) Chronic daily administration of selegiline and EGb 761 increases brain's resistance to ischemia in mice. Brain Research 917, 174-181.
    • (2001) Brain Research , vol.917 , pp. 174-181
    • Unal, I.1    Gursoy-Ozdemir, Y.2    Bolay, H.3    Soylemezoglu, F.4    Saribas, O.5    Dalkara, T.6
  • 62
    • 78651181230 scopus 로고
    • A simplified lead stain for use in electron microscopy
    • VENABLE, J. R. & COGGESHALL, R. (1965) A simplified lead stain for use in electron microscopy. Journal of Cell Biology 25, 407-408.
    • (1965) Journal of Cell Biology , vol.25 , pp. 407-408
    • Venable, J.R.1    Coggeshall, R.2
  • 63
    • 0031890109 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: Time course and modification by (-)-deprenyl
    • WADIA, J. S., CHALMERS-REDMAN, R. M., JU, W. J., CARLILE, G. W., PHILLIPS, J. L., FRASER, A. D. & TATTON, W. G. (1998) Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: Time course and modification by (-)-deprenyl. Journal of Neuroscience 18, 932-947.
    • (1998) Journal of Neuroscience , vol.18 , pp. 932-947
    • Wadia, J.S.1    Chalmers-Redman, R.M.2    Ju, W.J.3    Carlile, G.W.4    Phillips, J.L.5    Fraser, A.D.6    Tatton, W.G.7
  • 65
    • 0025051227 scopus 로고
    • Relationships between the mitochondrial transmembrane potential, ATP concentration, and cytotoxicity in isolated rat hepatocytes
    • WU, E. Y., SMITH, M. T., BELLOMO, G. & DI MONTE, D. (1990) Relationships between the mitochondrial transmembrane potential, ATP concentration, and cytotoxicity in isolated rat hepatocytes. Archives of Biochemistry & Biophysics 282, 358-362.
    • (1990) Archives of Biochemistry & Biophysics , vol.282 , pp. 358-362
    • Wu, E.Y.1    Smith, M.T.2    Bellomo, G.3    Di Monte, D.4
  • 66
    • 0035231122 scopus 로고    scopus 로고
    • Drugs to prevent cell death in Parkinson's disease. Neuroprotection against oxidative stress and inflammatory gene expression
    • YOUDIM, M., GRUNBLATT, E., LEVITES-ROYAK, Y. & MANDEL, S. (2001) Drugs to prevent cell death in Parkinson's disease. Neuroprotection against oxidative stress and inflammatory gene expression. Advances in Neurolology 87, 115-124.
    • (2001) Advances in Neurolology , vol.87 , pp. 115-124
    • Youdim, M.1    Grunblatt, E.2    Levites-Royak, Y.3    Mandel, S.4
  • 67
    • 0037198060 scopus 로고    scopus 로고
    • Novel neuroprotective anti-Alzheimer drugs with anti-depressant activity derived from the anti-Parkinson drug, rasagiline
    • YOUDIM, M. B. & WEINSTOCK, M. (2002) Novel neuroprotective anti-Alzheimer drugs with anti-depressant activity derived from the anti-Parkinson drug, rasagiline. Mechanisms of Ageing & Development 123, 1081-1086.
    • (2002) Mechanisms of Ageing & Development , vol.123 , pp. 1081-1086
    • Youdim, M.B.1    Weinstock, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.