Reaction and binding of oligodeoxynucleotides containing analogues of O6-methylguanine with wild-type and mutant human O6-alkylguanine-DNA alkyltransferase

Biochemistry

Volumn 38, Issue 21, 1999, Pages 6801-6806

  Spratt, Thomas E ^a   Wu, Jeffrey D ^a   Levy, Douglas E ^a   Kanugula, Sreenivas ^b   Pegg, Anthony E ^b  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLGUANIDINE; OLIGODEOXYNUCLEOTIDE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; TRANSFERASE;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPAIR; ELECTROPHORETIC MOBILITY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; PRIORITY JOURNAL; REACTION TIME;

BINDING SITES; DNA REPAIR; GUANINE; HUMANS; KINETICS; MUTAGENESIS; NUCLEIC ACID HETERODUPLEXES; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ADA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0033602914     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982908w     Document Type: Article

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