-
1
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
ELBASHIR SM, HARBORTH J, LENDECKEL W et al.: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 411(6836):494-498.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
2
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
CAPLEN NJ, PARRISH S, IMANI F, FIRE A, MORGAN RA: Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA (2001) 98(17):9742-9747.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.17
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
4
-
-
0021194459
-
Cytogenetics of leukemia
-
SPARKES RS: Cytogenetics of leukemia. N. Engl. J. Med. (1984) 311:848-850.
-
(1984)
N. Engl. J. Med.
, vol.311
, pp. 848-850
-
-
Sparkes, R.S.1
-
6
-
-
0032717039
-
The role of chromosome translocations in leukemogenesis
-
ROWLEY JD: The role of chromosome translocations in leukemogenesis. Semin. Hematol. (1999) 36(4 Suppl. 7):59-72.
-
(1999)
Semin. Hematol.
, vol.36
, Issue.4 SUPPL. 7
, pp. 59-72
-
-
Rowley, J.D.1
-
7
-
-
0025348013
-
Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
-
LUGO TG, PENDERGAST AM, MÅLLER AJ, WITTE ON: Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science (1990) 247:1079-1082.
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Måller, A.J.3
Witte, O.N.4
-
8
-
-
0035496899
-
Chronic myeloid leukemia: Current treatment options
-
GOLDMAN JM, DRUKER BJ: Chronic myeloid leukemia: current treatment options. Blood (2001) 98(7):2039-2042.
-
(2001)
Blood
, vol.98
, Issue.7
, pp. 2039-2042
-
-
Goldman, J.M.1
Druker, B.J.2
-
9
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
WILDA M, FUCHS U, WOSSMANN W, BORKHARDT A: Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene (2002) 21(37):5716-5724.
-
(2002)
Oncogene
, vol.21
, Issue.37
, pp. 5716-5724
-
-
Wilda, M.1
Fuchs, U.2
Wossmann, W.3
Borkhardt, A.4
-
10
-
-
0037441756
-
Specific inhibition of bcr-abl gene expression by small interfering RNA
-
SCHERR M, BATTMER K, WINKLER T et al.: Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood (2003) 101(4):1566-1569.
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1566-1569
-
-
Scherr, M.1
Battmer, K.2
Winkler, T.3
-
11
-
-
0034254368
-
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: Diverse mechanisms of resistance
-
MAHON FX, DEININGER MW, SCHULTHEIS B et al.: Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance. Blood (2000) 96(3):1070-1079.
-
(2000)
Blood
, vol.96
, Issue.3
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.2
Schultheis, B.3
-
12
-
-
0035929673
-
Roots of clinical resistance to STI-571 cancer therapy
-
BARTHE C, CONY-MAKHOUL P, MELO JV, MAHON JR: Roots of clinical resistance to STI-571 cancer therapy. Science (2001) 293(5538):2163.
-
(2001)
Science
, vol.293
, Issue.5538
, pp. 2163
-
-
Barthe, C.1
Cony-Makhoul, P.2
Melo, J.V.3
Mahon, J.R.4
-
13
-
-
0035929652
-
Roots of clinical resistance to STI-571 cancer therapy
-
HOCHHAUS A, KREIL S, CORBIN A et al.: Roots of clinical resistance to STI-571 cancer therapy. Science (2001) 293(5538):2163.
-
(2001)
Science
, vol.293
, Issue.5538
, pp. 2163
-
-
Hochhaus, A.1
Kreil, S.2
Corbin, A.3
-
14
-
-
0141790842
-
Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571)
-
WOHLBOLD L, VAN DER KUIP H, MIETHING C et al.: Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571). Blood (2003) 102(6):2236-2239.
-
(2003)
Blood
, vol.102
, Issue.6
, pp. 2236-2239
-
-
Wohlbold, L.1
Van Der Kuip, H.2
Miething, C.3
-
15
-
-
3042725365
-
Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin
-
CHEN J, WALL NR, KOCHER K et al.: Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin. J. Clin. Invest. (2004) 113(12):1784-1791.
-
(2004)
J. Clin. Invest.
, vol.113
, Issue.12
, pp. 1784-1791
-
-
Chen, J.1
Wall, N.R.2
Kocher, K.3
-
16
-
-
0028224348
-
Fusion of the PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
-
GOLUB TR, BARKER GF, LOVETT M, GILLILAND DG: Fusion of the PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell (1994) 77:307-316.
-
(1994)
Cell
, vol.77
, pp. 307-316
-
-
Golub, T.R.1
Barker, G.F.2
Lovett, M.3
Gilliland, D.G.4
-
17
-
-
0031958621
-
ALL1 gene alterations in acute leukemia: Biological and clinical aspects
-
CIMINO G, RAPANOTTI MC, SPROVIERI T, ELIA L: ALL1 gene alterations in acute leukemia: biological and clinical aspects. Haematologica (1998) 83(4):350-357.
-
(1998)
Haematologica
, vol.83
, Issue.4
, pp. 350-357
-
-
Cimino, G.1
Rapanotti, M.C.2
Sprovieri, T.3
Elia, L.4
-
19
-
-
0028349911
-
11q23/MLL rearrangement confers a poor prognosis in infants with acute lymphoblastic leukemia
-
PUI CH, BEHM FG, DOWNING JR et al.: 11q23/MLL rearrangement confers a poor prognosis in infants with acute lymphoblastic leukemia. J. Clin. Oncol. (1994) 12(5):909-915.
-
(1994)
J. Clin. Oncol.
, vol.12
, Issue.5
, pp. 909-915
-
-
Pui, C.H.1
Behm, F.G.2
Downing, J.R.3
-
20
-
-
0032831130
-
Mll rearrangements in haematological malignancies: Lessons from clinical and biological studies
-
DIMARTINO JF, CLEARY ML: Mll rearrangements in haematological malignancies: lessons from clinical and biological studies. Br. J. Haematol. (1999) 106(3):614-626.
-
(1999)
Br. J. Haematol.
, vol.106
, Issue.3
, pp. 614-626
-
-
Dimartino, J.F.1
Cleary, M.L.2
-
21
-
-
0344246893
-
Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia
-
DORDELMANN M, REITER A, BORKHARDT A et al.: Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia. Blood (1999) 94(4):1209-1217.
-
(1999)
Blood
, vol.94
, Issue.4
, pp. 1209-1217
-
-
Dordelmann, M.1
Reiter, A.2
Borkhardt, A.3
-
22
-
-
0034518313
-
Acute lymphoblastic leukemia in children
-
PUI CH: Acute lymphoblastic leukemia in children. Curr. Opin. Oncol. (2000) 12(1):3-12.
-
(2000)
Curr. Opin. Oncol.
, vol.12
, Issue.1
, pp. 3-12
-
-
Pui, C.H.1
-
23
-
-
0036739807
-
Infant acute lymphoblastic leukemia - Combined cytogenetic, immunophenotypical and molecular analysis of 77 cases
-
BORKHARDT A, WUCHTER C, VIEHMANN S et al.: Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases. Leukemia (2002) 16(9):1685-1690.
-
(2002)
Leukemia
, vol.16
, Issue.9
, pp. 1685-1690
-
-
Borkhardt, A.1
Wuchter, C.2
Viehmann, S.3
-
24
-
-
18544375333
-
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
-
ARMSTRONG SA, STAUNTON JE, SILVERMAN LB et al.: MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat. Genet. (2002) 30(1):41-47.
-
(2002)
Nat. Genet.
, vol.30
, Issue.1
, pp. 41-47
-
-
Armstrong, S.A.1
Staunton, J.E.2
Silverman, L.B.3
-
25
-
-
0037732933
-
Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events
-
DEBERNARDI S, LILLINGTON DM, CHAPLIN T et al.: Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events. Genes Chromosomes Cancer (2003) 37(2):149-158.
-
(2003)
Genes Chromosomes Cancer
, vol.37
, Issue.2
, pp. 149-158
-
-
Debernardi, S.1
Lillington, D.M.2
Chaplin, T.3
-
26
-
-
0032822953
-
The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
-
DOWNING JR: The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance. Br. J. Haematol. (1999) 106(2):296-308.
-
(1999)
Br. J. Haematol.
, vol.106
, Issue.2
, pp. 296-308
-
-
Downing, J.R.1
-
27
-
-
0027218725
-
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript
-
MIYOSHI H, KOZU T, SHIMIZU K et al.: The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J. (1993) 12:2715-2721.
-
(1993)
EMBO J.
, vol.12
, pp. 2715-2721
-
-
Miyoshi, H.1
Kozu, T.2
Shimizu, K.3
-
28
-
-
0345167904
-
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element
-
MULLOY JC, CAMMENGA J, BERGUIDO FJ et al.: Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element. Blood (2003) 102(13):4369-4376.
-
(2003)
Blood
, vol.102
, Issue.13
, pp. 4369-4376
-
-
Mulloy, J.C.1
Cammenga, J.2
Berguido, F.J.3
-
29
-
-
0034252564
-
Inducible chromosomal translocation of AML1 and ETO genes through Cre/toxP-mediated recombination in the mouse
-
BUCHHOLZ F, REFAELI Y, TRUMPP A, BISHOP JM: Inducible chromosomal translocation of AML1 and ETO genes through Cre/toxP-mediated recombination in the mouse. EMBO Rep. (2000) 1(2):133-139.
-
(2000)
EMBO Rep.
, vol.1
, Issue.2
, pp. 133-139
-
-
Buchholz, F.1
Refaeli, Y.2
Trumpp, A.3
Bishop, J.M.4
-
30
-
-
0036095217
-
The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells
-
MULLOY JC, CAMMENGA J, MACKENZIE KL et al.: The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood (2002) 99(1):15-23.
-
(2002)
Blood
, vol.99
, Issue.1
, pp. 15-23
-
-
Mulloy, J.C.1
Cammenga, J.2
Mackenzie, K.L.3
-
31
-
-
0025817842
-
Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation
-
ASOU H, TASHIRO S, HAMAMOTO K et al.: Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation. Blood (1991) 77(9):2031-2036.
-
(1991)
Blood
, vol.77
, Issue.9
, pp. 2031-2036
-
-
Asou, H.1
Tashiro, S.2
Hamamoto, K.3
-
32
-
-
0028962455
-
Establishment of a myeloid leukaemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression
-
MATOZAKI S, NAKAGAWA T, KAWAGUCHI R et al.: Establishment of a myeloid leukaemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression. Br. J. Haematol. (1995) 89(4):805-811.
-
(1995)
Br. J. Haematol.
, vol.89
, Issue.4
, pp. 805-811
-
-
Matozaki, S.1
Nakagawa, T.2
Kawaguchi, R.3
-
33
-
-
0038047685
-
AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells
-
HEIDENREICH O, KRAUTER J, RIEHLE H et al.: AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells. Blood (2003) 101(8):3157-3163.
-
(2003)
Blood
, vol.101
, Issue.8
, pp. 3157-3163
-
-
Heidenreich, O.1
Krauter, J.2
Riehle, H.3
-
34
-
-
13144264116
-
The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells
-
MARTINEZ N, DRESCHER B, RIEHLE H et al.: The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells. BMC Cancer (2004) 4(1):44.
-
(2004)
BMC Cancer
, vol.4
, Issue.1
, pp. 44
-
-
Martinez, N.1
Drescher, B.2
Riehle, H.3
-
35
-
-
0027265454
-
Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction
-
KOZU T, MIYOSHI H, SHIMIZU K et al.: Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction. Blood (1993) 82(4):1270-1276.
-
(1993)
Blood
, vol.82
, Issue.4
, pp. 1270-1276
-
-
Kozu, T.1
Miyoshi, H.2
Shimizu, K.3
-
36
-
-
0036674617
-
Live or let die: The cell's response to p53
-
VOUSDEN KH, LU X: Live or let die: the cell's response to p53. Nat. Rev. Cancer (2002) 2(8):594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.8
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
37
-
-
0037220020
-
TP53 in hematological cancer: Low incidence of mutations with significant clinical relevance
-
PELLER S, ROTTER V: TP53 in hematological cancer: low incidence of mutations with significant clinical relevance. Hum. Mutat. (2003) 21(3):277-284.
-
(2003)
Hum. Mutat.
, vol.21
, Issue.3
, pp. 277-284
-
-
Peller, S.1
Rotter, V.2
-
38
-
-
0037069330
-
Synthetic small inhibiting RNAs: Efficient tools to inactivate oncogenic mutations and restore p53 pathways
-
MARTINEZ LA, NAGUIBNEVA I, LEHRMANN H et al.: Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. Proc. Natl. Acad. Sci. USA (2002) 99(23):14849-14854.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.23
, pp. 14849-14854
-
-
Martinez, L.A.1
Naguibneva, I.2
Lehrmann, H.3
-
39
-
-
1342311013
-
The role of signal transducer and activator of transcription factors in leukemogenesis
-
STERNBERG DW, GILLILAND DG: The role of signal transducer and activator of transcription factors in leukemogenesis. J. Clin. Oncol. (2004) 22(2):361-371.
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.2
, pp. 361-371
-
-
Sternberg, D.W.1
Gilliland, D.G.2
-
40
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
KONNIKOVA L, KOTECKI M, KRUGER MM, COCHRAN BH: Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer (2003) 3(1):23.
-
(2003)
BMC Cancer
, vol.3
, Issue.1
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
41
-
-
85117738183
-
Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells
-
In Press
-
CHATTERJEE M, STUEHMER T, HERRMANN P et al.: Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells. Blood(2004) (In Press).
-
(2004)
Blood
-
-
Chatterjee, M.1
Stuehmer, T.2
Herrmann, P.3
-
42
-
-
4344693346
-
Oncogene suppression by small interfering RNAs
-
HEIDENREICH O: Oncogene suppression by small interfering RNAs. Curr. Pharm. Biotech. (2004) 5(4):349-354.
-
(2004)
Curr. Pharm. Biotech.
, vol.5
, Issue.4
, pp. 349-354
-
-
Heidenreich, O.1
-
43
-
-
0037238848
-
Gene silencing mediated by small interfering RNAs in mammalian cells
-
SCHERR M, MORGAN MA, EDER M: Gene silencing mediated by small interfering RNAs in mammalian cells. Curr. Med. Chem. (2003) 10(3):245-256.
-
(2003)
Curr. Med. Chem.
, vol.10
, Issue.3
, pp. 245-256
-
-
Scherr, M.1
Morgan, M.A.2
Eder, M.3
-
44
-
-
1642523434
-
Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL)
-
RITTER U, DAMM-WELK C, FUCHS U et al.: Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL). Oligonucleotides (2003) 13(5):365-373.
-
(2003)
Oligonucleotides
, vol.13
, Issue.5
, pp. 365-373
-
-
Ritter, U.1
Damm-Welk, C.2
Fuchs, U.3
-
45
-
-
1242316928
-
Biodistribution of phosphodiester and phosphorothioate siRNA
-
BRAASCH DA, PAROO Z, CONSTANTINESCU A et al.: Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorg. Med. Chem. Lett (2004) 14(5):1139-1143.
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, Issue.5
, pp. 1139-1143
-
-
Braasch, D.A.1
Paroo, Z.2
Constantinescu, A.3
-
46
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
BRAASCH DA, JENSEN S, LIU Y et al.: RNA interference in mammalian cells by chemically-modified RNA. Biochemistry (2003) 42(26):7967-7975.
-
(2003)
Biochemistry
, vol.42
, Issue.26
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
-
47
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
CZAUDERNA F, FECHTNER M, DAMES S et al.: Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. (2003) 31(11):2705-2716.
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.11
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
-
48
-
-
0036811055
-
Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs
-
HAMADA M, OHTSUKA T, KAWAIDA R et al.: Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs. Antisense Nucleic Acid Drug Dev. (2002) 12(5);301-309.
-
(2002)
Antisense Nucleic Acid Drug Dev.
, vol.12
, Issue.5
, pp. 301-309
-
-
Hamada, M.1
Ohtsuka, T.2
Kawaida, R.3
-
49
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
HARBORTH J, ELBASHIR SM, VANDENBURGH K et al.: Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev. (2003) 13(2):83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, Issue.2
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
-
50
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
SØRENSEN DR, LEIRDAL M, SIOUD M: Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. (2003) 327(4):761-766.
-
(2003)
J. Mol. Biol.
, vol.327
, Issue.4
, pp. 761-766
-
-
Sørensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
51
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
LEWIS DL, HAGSTROM JE, LOOMIS AG, WOLFF JA, HERWEIJER H: Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. (2002) 32(1):107-108.
-
(2002)
Nat. Genet.
, vol.32
, Issue.1
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
52
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
SONG E, LEE SK, WANG J et al.: RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. (2003) 9(3):347-351.
-
(2003)
Nat. Med.
, vol.9
, Issue.3
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
-
53
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
LIU F, SONG Y, LIU D: Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. (1999) 6(7):1258-1266.
-
(1999)
Gene Ther.
, vol.6
, Issue.7
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
54
-
-
0029160083
-
A versatile vector for gene and oligonudeotide transfer into cells in culture and in vivo: Polyethylenimine
-
BOUSSIF O, LEZOUALC'H F, ZANTA MA et al.: A versatile vector for gene and oligonudeotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. USA (1995) 92(16)7297-7301.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, Issue.16
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
-
55
-
-
0141595996
-
Linear polyethylenimine as a tool for comparative studies of antisense and short double-stranded RNA oligonucleotides
-
BOLOGNA JC, DORN G, NATT F, WEILER J: Linear polyethylenimine as a tool for comparative studies of antisense and short double-stranded RNA oligonucleotides. Nucleosides Nucleotides Nucleic Acids (2003) 22(5-8):1729-1731.
-
(2003)
Nucleosides Nucleotides Nucleic Acids
, vol.22
, Issue.5-8
, pp. 1729-1731
-
-
Bologna, J.C.1
Dorn, G.2
Natt, F.3
Weiler, J.4
-
56
-
-
0036245743
-
Expanding small RNA interference
-
TUSCHL T: Expanding small RNA interference. Nat. Biotechnol. (2002) 20(5):446-448.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.5
, pp. 446-448
-
-
Tuschl, T.1
-
57
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
BRUMMELKAMP TR, BERNARDS R, AGAMI R: A system for stable expression of short interfering RNAs in mammalian cells. Science (2002) 296(5567):550-553.
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
58
-
-
0036245628
-
U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
-
MIYAGISHI M, TAIRA K: U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. (2002) 20(5):497-500.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.5
, pp. 497-500
-
-
Miyagishi, M.1
Taira, K.2
-
59
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
PAUL CP, GOOD PD, WINER I, ENGELKE DR: Effective expression of small interfering RNA in human cells. Nat. Biotechnol. (2002) 20(5):505-508.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.5
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
60
-
-
0141611749
-
Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA
-
SCHERR M, BATTMER K, GANSER A, EDER M: Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle (2003) 2(3):251-257.
-
(2003)
Cell Cycle
, vol.2
, Issue.3
, pp. 251-257
-
-
Scherr, M.1
Battmer, K.2
Ganser, A.3
Eder, M.4
-
61
-
-
26444554618
-
Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors
-
FISH RJ, KRUITHOF EK: Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors. BMC Mol. Biol. (2004) 5(1):9.
-
(2004)
BMC Mol. Biol.
, vol.5
, Issue.1
, pp. 9
-
-
Fish, R.J.1
Kruithof, E.K.2
-
62
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
HACEIN-BEY-ABINA S, VON KALLE C, SCHMIDT M et al.: LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science (2003) 302(5644):415-419.
-
(2003)
Science
, vol.302
, Issue.5644
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
63
-
-
2442495329
-
RISC is a 5′ phosphomonoester-producing RNA endonuclease
-
MARTINEZ J, TUSCHL T: RISC is a 5′ phosphomonoester-producing RNA endonuclease. Genes Dev. (2004) 18(9):975-980.
-
(2004)
Genes Dev.
, vol.18
, Issue.9
, pp. 975-980
-
-
Martinez, J.1
Tuschl, T.2
-
64
-
-
0142173075
-
Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
-
SAXENA S, JONSSON ZO, DUTTA A: Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem. (2003) 278(45):44312-44319.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.45
, pp. 44312-44319
-
-
Saxena, S.1
Jonsson, Z.O.2
Dutta, A.3
-
65
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
JACKSON AL, BARTZ SR, SCHELTER J et al.: Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. (2003) 21(6):635-637.
-
(2003)
Nat. Biotechnol.
, vol.21
, Issue.6
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
-
66
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
BRIDGE AJ, PEBERNARD S, DUCRAUX A, NICOULAZ AL, IGGO R: Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. (2003) 34(3):263-264.
-
(2003)
Nat. Genet.
, vol.34
, Issue.3
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
67
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
SLEDZ CA, HOLKO M, DE VEER MJ, SILVERMAN RH, WILLIAMS BR: Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. (2003) 5(9):834-839.
-
(2003)
Nat. Cell Biol.
, vol.5
, Issue.9
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
De Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
68
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
-
KIM DH, LONGO M, HAN Y et al.: Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat. Biotechnol. (2004) 22(3):321-325.
-
(2004)
Nat. Biotechnol.
, vol.22
, Issue.3
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
-
69
-
-
2442705429
-
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
-
KARIKO K, BHUYAN P, CAPODICI J, WEISSMAN D: Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. J. Immunol. (2004) 172(11):6545-6549.
-
(2004)
J. Immunol.
, vol.172
, Issue.11
, pp. 6545-6549
-
-
Kariko, K.1
Bhuyan, P.2
Capodici, J.3
Weissman, D.4
-
70
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
-
HOLEN T, AMARZGUIOUI M, WIIGER MT, BABAIE E, PRYDZ H: Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res. (2002) 30(8):1757-1766.
-
(2002)
Nucleic Acids Res.
, vol.30
, Issue.8
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
71
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
CHEN CZ, LI L, LODISH HF, BARTEL DP: MicroRNAs modulate hematopoietic lineage differentiation. Science (2004) 303(5654):83-86.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
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