Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene

Molecular Imaging and Biology

Volumn 6, Issue 6, 2004, Pages 395-404

  Liang, Qianwa ^a   Yamamoto, Masato ^b   Curiel, David T ^b   Herschman, Harvey R ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenovirus; COX 2; Cyclooxygenase; Gene therapy; Luciferase; Molecular imaging; Noninvasive imaging; Optical imaging; Retargeting; Transcriptional restriction

Indexed keywords

ADENOVIRUS VECTOR; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; LUCIFERASE; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; EXPERIMENTAL NEOPLASM; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; LIVER PARENCHYMA; MONITORING; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; OPTICAL INSTRUMENTATION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TARGET CELL; TRANSGENE; TUMOR XENOGRAFT; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION;

ADENOVIRIDAE; ANIMALS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; GENE THERAPY; GENES, REPORTER; HUMANS; INJECTIONS, INTRAVENOUS; LUCIFERASES, FIREFLY; LUNG NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TRANSCRIPTION, GENETIC; TRANSDUCTION, GENETIC; TRANSGENES;

ADENOVIRIDAE; ANIMALIA; CUCUMBER MOSAIC VIRUS;

EID: 10244266446     PISSN: 15361632     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mibio.2004.09.002     Document Type: Article

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