Phosphorylation of Tuberin as a Novel Mechanism for Somatic Inactivation of the Tuberous Sclerosis Complex Proteins in Brain Lesions

Cancer Research

Volumn 64, Issue 3, 2004, Pages 812-816

  Han, Sangyeul ^a   Santos, Túlio M ^a   Puga, Ana ^a   Roy, Jenn ^a   Thiele, Elizabeth A ^a   McCollin, Mia ^a   Stemmer Rachamimov, Anat ^a   Ramesh, Vijaya ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HAMARTIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; TUBERIN;

ARTICLE; BRAIN INJURY; COMPLEX FORMATION; ENZYME SUBSTRATE; GENE; GENE INACTIVATION; GENETIC ANALYSIS; HAMARTOMA; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SOMATIC MUTATION; TISSUE SPECIFICITY; TSC1 GENE; TSC2 GENE; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR GENE;

ASTROCYTOMA; BRAIN NEOPLASMS; ENZYME ACTIVATION; HUMANS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS; RIBOSOMAL PROTEIN S6 KINASES; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 0842325813     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3277     Document Type: Article

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