Genomics-based hypothesis generation: A novel approach to unravelling drug resistance in brain tumours?

Lancet Oncology

Volumn 5, Issue 2, 2004, Pages 89-100

  Bredel, Markus ^a,b   Bredel, Claudia ^a   Sikic, Branimir I ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC AGENT; DIHYDROFOLATE REDUCTASE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; METALLOTHIONEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN KINASE C; THYMIDYLATE SYNTHASE;

AWARENESS; BRAIN CANCER; BRAIN TUMOR; CANCER PATIENT; CHROMOSOME 19Q; CHROMOSOME 1P; CYTOGENETICS; DIFFERENTIAL DISPLAY; DISEASE MODEL; DNA DAMAGE; DNA MICROARRAY; DNA REPAIR; DRUG RESPONSE; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENOMICS; HETEROZYGOSITY LOSS; HUMAN; HYPOTHESIS; MEDICAL RESEARCH; MISMATCH REPAIR; MOLECULAR MECHANICS; MULTIDRUG RESISTANCE; PHARMACOGENOMICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SERIAL ANALYSIS OF GENE EXPRESSION; SUBTRACTIVE HYBRIDIZATION; TREATMENT OUTCOME;

BRAIN NEOPLASMS; DRUG RESISTANCE, NEOPLASM; GENOME, HUMAN; HUMANS; MODELS, GENETIC; MODELS, THEORETICAL;

EID: 0742323731     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(04)01382-8     Document Type: Review

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