Modulation of Oncogenic DBL Activity by Phosphoinositol Phosphate Binding to Pleckstrin Homology Domain

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19524-19531

  Russo, Chiara ^a   Gao, Yuan ^b   Mancini, Patrizia ^c   Vanni, Cristina ^a   Porotto, Matteo ^a   Falasca, Marco ^d   Torrisi, Maria Rosaria ^c   Zheng, Yi ^b   Eva, Alessandra ^a  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CATALYSIS; IMMUNOLOGY; LIPIDS; NUCLEIC ACIDS; PROTEINS;

HOMOLOGY; PLASMA MEMBRANES;

BIOCHEMISTRY;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; INOSITOL PHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PLECKSTRIN; PROTEIN CDC42; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN; MCF2 PROTEIN, MOUSE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; PHOSPHOPROTEIN; PLASMA PROTEIN; PLATELET PROTEIN P47; POLYPHOSPHOINOSITIDE;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL MEMBRANE; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; INHIBITION KINETICS; INSECT CELL; MODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; ANIMAL; CELL STRAIN 3T3; CELL STRAIN COS1; CHEMISTRY; DOSE RESPONSE; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; IMMUNOELECTRON MICROSCOPY; METABOLISM; MOUSE; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; TIME;

ANIMALIA; INSECTA;

3T3 CELLS; ANIMALS; BLOOD PROTEINS; CDC42 GTP-BINDING PROTEIN; CELL MEMBRANE; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MICE; MICROSCOPY, FLUORESCENCE; MICROSCOPY, IMMUNOELECTRON; MUTATION; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 0035375109     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009742200     Document Type: Article

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