Chronic inflammatory disorders of the gastrointestinal tract of companion animals

New Zealand Veterinary Journal

Volumn 51, Issue 6, 2003, Pages 262-274

  Cave, N J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cat; Companion animal; Diarrhoea; Dog; Enteritis; Gut flora; Immunopathology; Inflammatory bowel disease; Mucosal immunity

Indexed keywords

ANTIGEN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; ISOPROTEIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRACE ELEMENT; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL FOOD; B LYMPHOCYTE; BIFIDOBACTERIUM; CALORIC INTAKE; CANNED FOOD; CATABOLISM; CELL FUNCTION; CELL TYPE; CELLULAR IMMUNITY; CHRONIC INFLAMMATION; CLONAL VARIATION; CROHN DISEASE; CYTOKINE PRODUCTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DIETARY INTAKE; DIFFERENTIAL DIAGNOSIS; DIGESTIVE SYSTEM INFLAMMATION; ENDOSCOPY; ENTERITIS; EUBACTERIUM; GASTROINTESTINAL BIOPSY; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TUMOR; GENETIC SUSCEPTIBILITY; GLYCATION; HISTOPATHOLOGY; HUMAN; HYPOMAGNESEMIA; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; INTESTINE ABSORPTION; INTESTINE FLORA; INTESTINE MOTILITY; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; LACTOBACILLUS; LYMPHANGIECTASIS; LYMPHOCYTE CLONE; LYMPHOCYTIC INFILTRATION; LYMPHOSARCOMA; MACRONUTRIENT; MICROBIAL GROWTH; MUCOSAL IMMUNITY; NATURAL KILLER CELL; NONHUMAN; NUTRIENT DYNAMICS; NUTRITIONAL DEFICIENCY; REVIEW; STANDARDIZATION; TH1 CELL; TH2 CELL; ULCERATIVE COLITIS; VITAMIN K DEFICIENCY;

ANIMALIA; BIFIDOBACTERIUM; CANIS FAMILIARIS; FELIS CATUS; LACTOBACILLUS;

EID: 0348147394     PISSN: 00480169     EISSN: 11760710     Source Type: Journal    
DOI: 10.1080/00480169.2003.36380     Document Type: Article

References (110)

1. Abreu MT, Vora P, Faure E, Thomas LS, Arnold ET, Arditi M. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. Journal of Immunology 167, 1609-16, 2001
2. Adams RB, Planchon SM, Roche JK. IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding. Journal of Immunology 150, 2356-63, 1993
3. Akira S. Mammalian Toll-like receptors. Current Opinion in Immunology 15, 5-11, 2003
4. Altaf W Perveen S, Rehman KU, Teichberg S, Vancurova I, Harper RG, Wapnir RA. Zinc supplementation in oral rehydration solutions: experimental assessment and mechanisms of action. Journal of the American College of Nutrition 21, 26-32, 2002
5. Baez JL, Hendrick MJ, Walker LM, Washabau RJ. Radiographic, ultrasonographic, and endoscopic findings in cats with inflammatory bowel disease of the stomach and small intestine: 33 cases (1990-1997). Journal of the American Veterinary Medical Association 215, 349-54, 1999
6. Bamba T, Kanauchi O, Andoh A, Fujiyama Y. A new prebiotic from germinated barley for nutraceutical treatment of ulcerative colitis. Journal of Gastroenterology and Hepatology 17, 818-24, 2002
7. Berger SA. The use of antimicrobial agents for noninfectious diseases. Reviews of Infectious Diseases 7, 357-67, 1985
8. Brandtzaeg P. Nature and function of gastrointestinal antigen-presenting cells. Allergy 56 (Supplement 67), 16-20, 2001
9. Braun L, Lester S, Kuzma AB, Hosie SC. Gastric dilatation-volvulus in the dog with histological evidence of preexisting inflammatory bowel disease: a retrospective study of 23 cases. Journal of the American Animal Hospital Association 32, 287-90, 1996
10. Breitschwerdt EB. Immunoproliferative enteropathy of basenjis. Seminars in Veterinary Medicine and Surgery (Small Animal) 7, 153-61, 1992
11. Breslin NP, Nash C, Hilsden RJ, Hershfield NB, Price LM, Meddings JB, Sutherland LR. Intestinal permeability is increased in a proportion of spouses of patients with Crohn’s disease. American Journal of Gastroenterology 96, 2934-8, 2001
12. Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infection and Immunity 68, 7010-7, 2000
13. Center SA, Warner K, Corbett J, Randolph JF, Erb HN. Proteins invoked by vitamin K absence and clotting times in clinically ill cats. Journal ofVeterinary Internal Medicine 14, 292-7, 2000
14. Couto CG, Rutgers HC, Sherding RG, Rojko J. Gastrointestinal lymphoma in 20 dogs. A retrospective study. Journal of Veterinary Internal Medicine 3, 73-8, 1989
15. Dennis JS, Kruger JM, Mullaney TP. Lymphocytic/plasmacytic gastroenteritis in cats: 14 cases (1985-1990). Journal of the American Veterinary Medical Association 200,1712-8, 1992
16. Dennis JS, Kruger JM, Mullaney TP. Lymphocytic/plasmacytic colitis in cats: 14 cases (1985-1990). Journal of the American Veterinary Medical Association 202, 313-8, 1993
17. Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ. T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. American Journal of Pathology 150, 91-7, 1997
18. Dijkstra G, Moshage H, Jansen PL. Blockade of NF-kappa B activation and donation of nitric oxide: new treatment options in inflammatory bowel disease? Scandinavian Journal of Gastroenterology (Supplement), 37-41, 2002
19. Dreitz MJ, Ogilvie G, Sim GK. Rearranged T lymphocyte antigen receptor genes as markers of malignant T cells. Veterinary Immunology and Immunopathology 69,113-9, 1999
20. Farmer RG, Hawk WA, Turnbull RB Jr. Clinical patterns in Crohn’s disease: a statistical study of 615 cases. Gastroenterology 68, 627-35, 1975
21. Foley JE, Marks SL, Munson L, Melli A, Dewhirst FE, Yu S, Shen Z, Fox JG. Isolation of Helicobacter canis from a colony of Bengal cats with endemic diarrhea. Journal of Clinical Microbiology 37, 3271-5, 1999
22. Garden OA, Manners HK, Sorensen SH, Rutgers HC, Daniels S, Legrand-Defretin V, Batt RM. Intestinal permeability of Irish setter puppies challenged with a controlled oral dose of gluten. Research in Veterinary Science 65, 23-8, 1998
23. Garside P, Mowat AM, Oral tolerance. Seminars in Immunology 13, 177-85, 2001
24. Gassler N, Rohr C, Schneider A, Kartenbeck J, Bach A, Obermuller N, Otto HF, Autschbach F. Inflammatory bowel disease is associated with changes of enterocytic junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology 281, G216-G228, 2001
25. German AJ, Hall EJ, Kelly DF, Watson AD, Day MJ. An immunohistochemi-cal study of histiocytic ulcerative colitis in boxer dogs. Journal of Comparative Pathology 122, 163-75, 2000a
26. German AJ, Helps CR, Hall EJ, Day MJ. Cytokine mRNA expression in mucosal biopsies from German shepherd dogs with small intestinal enteropathies. Digestive Diseases and Sciences 45, 7-17, 2000b
27. German AJ, Hall EJ, Day MJ. Immune cell populations within the duodenal mucosa of dogs with enteropathies. Journal of Veterinary Internal Medicine 15, 14-25, 2001
28. German AJ, Day MJ, Ruaux CG, Steiner JM, Williams DA, Hall EJ. Comparison of direct and indirect tests for small intestinal bacterial overgrowth and antibiotic-responsive diarrhea in dogs. Journal of Veterinary Internal Medicine 17, 33-43, 2003
29. Gitter AH, Bendfeldt K, Schulzke JD, Fromm M. Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis. Federation of American Societies for Experimental Biology Journal 14, 1749-53, 2000
30. Gitter AH, Wullstein F, Fromm M, Schulzke JD. Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121, 1320-8, 2001
31. Goldstein RE, Greiter-Wilke A, McDonough SP, Simpson KW Quantitative evaluation of inflammatory and immune responses in cats with inflammatory bowel disease. Journal of Veterinary Internal Medicine 17 (Abstract), 411-2, 2003
32. Grisham MB, Pavlick KP, Laroux FS, Hoffman J, Bharwani S, Wolf RE. Nitric oxide and chronic gut inflammation: controversies in inflammatory bowel disease. Journal of Investigative Medicine 50, 272-83, 2002
33. Guarner F, Casellas F, Borruel N, Antolin M, Videla S, Vilaseca J, Malagelada Jr. Role of microecology in chronic inflammatory bowel diseases. European Journal of Clinical Nutrition 56 (Supplement 4), S34-8, 2002
34. Guilford WG, Jones BR, Markwell PJ, Arthur DG, Collett MG, Harte JG. Food sensitivity in cats with chronic idiopathic gastrointestinal problems. Journal ofVeterinary Internal Medicine 15, 7-13, 2001
35. Gunawardana SC, Jergens AE, Ahrens FA, Niyo Y. Colonic nitrite and immunoglobulin G concentrations in dogs with inflammatory bowel disease. Journal of the American Veterinary Medical Association 211, 318-21, 1997
36. Hanada T, Yoshimura A. Regulation of cytokine signaling and inflammation. Cytokine Growth Factor Reviews 13, 413-21, 2002
37. Hart JR, Shaker E, Patnaik AK, Garvey MS. Lymphocytic-plasmacytic enterocolitis in cats: 60 cases (1988-1990). Journal of the American Animal Hospital Association 30, 505-14, 1994
38. Hausmann M, Kiessling S, Mestermann S, Webb G, Spottl T, Andus T, Scholmerich J, Herfarth H, Ray K, Falk W Rogler G. Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. Gastroenterology 122, 1987-2000, 2002
39. Hayden DW, Van Kruiningen HJ. Lymphocytic-plasmacytic enteritis in German Shepherd dogs. Journal of the American Animal Hospital Association 18, 89-96, 1982
40. Heine H, Lien E. Toll-like receptors and their function in innate and adaptive immunity. International Archives of Allergy and Immunology 130, 180-92, 2003
41. Hendrick M. A spectrum of hypereosinophilic syndromes exemplified by six cats with eosinophilic enteritis. Veterinary Pathology 18, 188-200, 1981
42. Hirt R, Iben C. Possible food allergy in a colony of cats. Journal of Nutrition 128 (Supplement), S2792-4, 1998
43. Irvine EJ, Marshall JK. Increased intestinal permeability precedes the onset of Crohn’s disease in a subject with familial risk. Gastroenterology 119, 1740-4, 2000
44. Jacobs G, Collins-Kelly L, Lappin MR, Tyler D. Lymphocytic-plasmacytic enteritis in 24 dogs. Journal ofVeterinary Internal Medicine 4, 45-53, 1990
45. Jadcherla SR. Inflammation inhibits muscarinic signaling in in vivo canine colonic circular smooth muscle cells. Pediatric Research 52, 756-62, 2002
46. Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA. In vivo activation of antigen-specific CD4 T cells. Annual Review of Immunology 19, 23-45, 2001
47. Jensen GL, McGarvey N, Taraszewski R, Wixson SK, Seidner DL, Pai T, Yeh YY, Lee TW DeMichele SJ. Lymphatic absorption of enterally fed structured triacylglycerol vs physical mix in a canine model. American Journal of Clinical Nutrition 60, 518-24, 1994
48. Jergens AE. Rational use of antimicrobials for gastrointestinal disease in small animals. Journal of the American Animal Hospital Association 30, 123-31, 1994
49. Jergens AE. Inflammatory bowel disease. Current perspectives. Veterinary Clinics of North America - Small Animal Practice 29, 501-21, 1999
50. Jergens AE, Moore FM, Haynes JS, Miles KG. Idiopathic inflammatory bowel disease in dogs and cats: 84 cases (1987-1990). Journal of the American Veterinary Medical Association 201, 1603-8, 1992
51. Jergens AE, Moore FM, Kaiser MS, Haynes JS, Kinyon JM. Morphometric evaluation of immunoglobulin A-containing and immunoglobulin G-con-taining cells and T cells in duodenal mucosa from healthy dogs and from dogs with inflammatory bowel disease or nonspecific gastroenteritis. American Journal of Veterinary Research 57, 697-704, 1996
52. Jergens AE, Carpenter SL, Wannemuehler Y. Molecular detection of inducible nitric oxide synthase in canine inflammatory bowel disease. Journal of Veterinary Internal Medicine 12, 205, 1998
53. Jergens AE, Gamet Y, Moore FM, Niyo Y, Tsao C, Smith B. Colonic lymphocyte and plasma cell populations in dogs with lymphocytic-plasmacytic colitis. American Journal of Veterinary Research 60, 515-20, 1999
54. Jergens AE, Schreiner CA, Frank DE, Niyo Y, Ahrens FE, Eckersall PD, Benson TJ, Evans R. A scoring index for disease activity in canine inflammatory bowel disease. Journal ofVeterinary Internal Medicine 17, 291-7, 2003
55. Johnson SE. Canine eosinophilic gastroenterocolitis. Seminars in Veterinary Medicine and Surgery (Small Animat) 7, 145-52, 1992
56. Kanauchi O, Suga T, Tochihara M, Hibi T, Naganuma M, Homma T, Asakura H, Nakano H, Takahama K, Fujiyama Y, Andoh A, Shimoyama T, Hida N, Haruma K, Koga H, Mitsuyama K, Sata M, Fukuda M, Kojima A, Bamba T. Treatment of ulcerative colitis by feeding with germinated barley foodstuff: first report of a multicenter open control trial. Journal of Gastroenterology 37 (Supplement 14), 67-72, 2002
57. Kellermann SA, McEvoy LM. The Peyer’s patch microenvironment suppresses T cell responses to chemokines and other stimuli. Journal of Immunology 167, 682-90, 2001
58. Kim SW, Rogers QR, Morris JG. Dietary antibiotics decrease taurine loss in cats fed a canned heat-processed diet. Journal of Nutrition 126, 509-15, 1996
59. Kliewer SA, Sundseth SS, Jones SA, Brown PJ, Wisely GB, Koble CS, Devchand P, Wahli W Willson TM, Lenhard JM, Lehmann JM. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proceedings of the National Academy of Sciences of the United States of America 94, 4318-23, 1997
60. Knowles DM. Immunophenotypic and antigen receptor gene rearrangement analysis in T cell neoplasia. American Journal of Pathology 134, 761-85, 1989
61. Lappin MR, Dowers K, Edsell D, Taton-Allen GF, Cheney J. Cryptosporidiosis and inflammatory bowel disease in a cat. Feline Practice 25, 10-13, 1997
62. Larsen JA, Calvert CC, Rogers QR. Processing of dietary casein decreases bioavailability of lysine in growing kittens. Journal of Nutrition 132 (Supplement), S1748S-S1750, 2002
63. Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G, Hwang DH. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. Journal of Lipid Research. 44, 479-86, 2003
64. Linskens RK, Huijsdens XW Savelkoul PH, Vandenbroucke-Grauls CM, Meuwissen SG. The bacterial flora in inflammatory bowel disease: current insights in pathogenesis and the influence of antibiotics and probiotics. Scandinavian Journal of Gastroenterology (Supplement), 29-40, 2001
65. Littman MP, Dambach DM, Vaden SL, Giger U. Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997). Journal ofVeterinary Internal Medicine 14, 68-80, 2000
66. Liu X, Rusch NJ, Striessnig J, Sarna SK. Down-regulation of L-type calcium channels in inflamed circular smooth muscle cells of the canine colon. Gastroenterology 120, 480-9, 2001
67. Locher C, Tipold A, Welle M, Busato A, Zurbriggen A, Griot-Wenk ME. Quantitative assessment of mast cells and expression of IgE protein and mRNA for IgE and interleukin 4 in the gastrointestinal tract of healthy dogs and dogs with inflammatory bowel disease. American Journal of Veterinary Research 62, 211-6, 2001
68. Luckschander N, Allenspach K, Styner M, Doherr M, Seibold F, Gaschen F. Validation of serologic markers of disease activity (pANCA and ASCA) in dogs with inflammatory bowel disease. Journal ofVeterinary Internal Medicine 17 (Abstract), 414, 2003
69. MacLachlan NJ, Breitschwerdt EB, Chambers JM, Argenzio RA, De Buyss-cher EV. Gastroenteritis of Basenji dogs. Veterinary Pathology 25, 36-41, 1988
70. Mahler M, Leiter EH. Genetic and environmental context determines the course of colitis developing in IL-10-deficient mice. Inflammatory Bowel Diseases 8, 347-55, 2002
71. Manthey MW Ross AB, Soergel KH. Cryptosporidiosis and inflammatory bowel disease. Experience from the Milwaukee outbreak. Digestive Diseases and Sciences 42, 1580-6, 1997
72. Marks SL, Laflamme D, McCandlish AP. Dietary trial using a commercial hy-poallergenic diet containing hydrolyzed protein for dogs with inflammatory bowel disease. Veterinary Therapeutics 3, 109-18, 2002
73. Martin L, Matteson V, Wingfield W. Abnormalities of serum magnesium in critically ill dogs: incidence and implications. Journal ofVeterinary Emergency and Critical Care 4, 15-20, 1994
74. Mayoral I, Pena L, Rodriguez-Franco F, Sainz A, Tesouro MA, Ynaraja E. Immunohistological study of IgA, IgG and IgM in endoscopic biopsies of dogs with plasmacytic-lymphocytic colitis. Zentralblatt für Veterinärmedizin. Reihe B43,613-20, 1996
75. Meddings JB, Kirk D, Olson ME. Noninvasive detection of nonsteroidal antiinflammatory drug-induced gastropathy in dogs. American Journal of Veterinary Research 56, 977-81, 1995
76. Muir P, Gruffydd-Jones TJ, Brown PJ. Hypereosinophilic syndrome in a cat. Veterinary Record 132, 358-9, 1993
77. Nelson RW Dimperio ME, Long GG. Lymphocytic-plasmacytic colitis in the cat. Journal of the American Veterinary Medical Association 184, 1133-5, 1984
78. Nelson RW Stookey LJ, Kazacos E. Nutritional management of idiopathic chronic colitis in the dog. Journal of Veterinary Internal Medicine 2, 133-7, 1988
79. Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annual Review of Medicine 51, 289-98, 2000
80. Pavlick KP, Laroux FS, Fuseler J, Wolf RE, Gray L, Hoffman J, Grisham MB. Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease. Free Radical Biology and Medicine 33, 311-22, 2002
81. Pearson M, Teahon K, Levi AJ, Bjarnason I. Food intolerance and Crohn’s disease. Gut 34, 783-7, 1993
82. Perner A, Rask-Madsen J. Review article: the potential role of nitric oxide in chronic inflammatory bowel disorders. Alimentary Pharmacology and Therapeutics 13,135-44, 1999
83. Peterson JL, Willard MD, Lees GE, Lappin MR, Dieringer T, Floyd E. Toxoplasmosis in two cats with inflammatory intestinal disease. Journal of the American Veterinary Medical Association 199, 473-6, 1991
84. Ramakrishna BS, Mathan M, Mathan VI. Alteration of colonic absorption by long-chain unsaturated fatty acids. Influence of hydroxylation and degree of unsaturation. Scandinavian Journal of Gastroenterology 29, 54-8, 1994
85. Ridgway J, Jergens AE, Niyo Y. Possible causal association of idiopathic inflammatory bowel disease with thrombocytopenia in the dog. Journal of the American Animal Hospital Association 37, 65-74, 2001
86. Ridyard AE, Nuttall TJ, Else RW, Simpson JW, Miller HR. Evaluation of Th1, Th2 and immunosuppressive cytokine mRNA expression within the colonic mucosa of dogs with idiopathic lymphocytic-plasmacytic colitis. Veterinary Immunology and Immunopathology 86, 205-14, 2002
87. Ristic JM, Stidworthy MF. Two cases of severe iron-deficiency anaemia due to inflammatory bowel disease in the dog. Journal of Small Animal Practice 43, 80-3, 2002
88. Rutgers HC, Batt RM, Kelly DF. Lymphocytic-plasmacytic enteritis associated with bacterial overgrowth in a dog. Journal of the American Veterinary Medical Association 192, 1739-42, 1988
89. Rutgers HC, Batt RM, Elwood CM, Lamport A. Small intestinal bacterial overgrowth in dogs with chronic intestinal disease. Journal of the American Veterinary Medical Association 206, 187-93, 1995
90. Rutgers HC, Batt RM, Proud FJ, Sorensen SH, Elwood CM, Petrie G, Mat-thewman LA, Forster-van Hijfte MA, Boswood A, Entwistle M, Fensome RH. Intestinal permeability and function in dogs with small intestinal bacterial overgrowth. Journal of Small Animal Practice 37, 428-34, 1996
91. Schurmann G, Bruwer M, Klotz A, Schmid KW Senninger N, Zimmer KP. Transepithelial transport processes at the intestinal mucosa in inflammatory bowel disease. International Journal of Colorectal Disease 14, 41-6, 1999
92. Sepulveda AR, Coelho LG. Helicobacter pylori and gastric malignancies. Helicobacter 7 (Supplement 1), 37-42, 2002
93. Sethi AK, Sarna SK. Colonic motor response to a meal in acute colitis. Gastroenterology 101, 1537-46, 1991
94. Simpson KW, Fyfe J, Cornetta A, Sachs A, Strauss-Ayali D, Lamb SV, Reimers TJ. Subnormal concentrations of serum cobalamin (vitamin B12) in cats with gastrointestinal disease. Journal ofVeterinary Internal Medicine 15, 26-32, 2001
95. Sturniolo GC, Di L, V, Ferronato A, D’Odorico A, D’Inca R. Zinc supplementation tightens “leaky gut” in Crohn’s disease. Inflammatory Bowel Diseases 7, 94-8, 2001
96. Szabo A, Boros M, Kaszaki J, Nagy S. The role of mast cells in mucosal permeability changes during ischemia-reperfusion injury of the small intestine. Shock 8, 284-91, 1997
97. Takagi T, Naito Y, Tomatsuri N, Handa O, Ichikawa H, Yoshida N, Yoshikawa T. Pioglitazone, a PPAR-gamma ligand, provides protection from dextran sulfate sodium-induced colitis in mice in association with inhibition of the NF-kappa B-cytokine cascade. Redox Report 7, 283-9, 2002
98. Tams TR. Feline inflammatory bowel disease. Veterinary Clinics of North America - Small Animal Practice 23, 569-86, 1993
99. Tanaka M, Riddell RH. The pathological diagnosis and differential diagnosis of Crohn’s disease. Hepatogastroenterology 37, 18-31, 1990
100. Toll J, Erb H, Birnbaum N, Schermerhorn T. Prevalence and incidence of serum magnesium abnormalities in hospitalized cats. Journal of Veterinary Internal Medicine 16, 217-21, 2002
101. Van Den BJ, Kamm MA, Knight SC. Immune sensitization to food, yeast and bacteria in Crohn’s disease. Alimentary Pharmacology and Therapeutics 15, 1647-53, 2001
102. Van Den BJ, Cahill J, Emmanuel AV Vaizey CJ, Talbot IC, Knight SC, Kamm MA. Gut mucosal response to food antigens in Crohn’s disease. Alimentary Pharmacology and Therapeutics 16, 1903-15, 2002
103. Vernau W Moore PF. An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction. Veterinary Immunology and Immunopathology 69, 145-64, 1999
104. Vibe-Petersen G. Canine lymphocytic plasmocytic enteritis: an immunopatho-logical investigation of intestinal plasma cells. Acta Veterinaria Scandinavica 32, 221-32, 1991
105. Wasmer ML, Willard MD, Helman RG, Edwards JF. Food intolerance mimicking alimentary lymphosarcoma. Journal of the American Animal Hospital Association 31, 463-6, 1995
106. Weiss DJ, Gagne JM, Armstrong PJ. Relationship between inflammatory hepatic disease and inflammatory bowel disease, pancreatitis, and nephritis in cats. Journal of the American Veterinary Medical Association 209, 1114-6, 1996
107. Wilcock B. Endoscopic biopsy interpretation in canine or feline enterocolitis. Seminars in Veterinary Medicine and Surgery (Small Animal) 7, 162-71, 1992
108. Willard MD, Leid RW. Nonuniform horizontal and vertical distributions of immunoglobulin A cells in canine intestines. American Journal of Veterinary Research 42, 1573-80, 1981
109. Willard MD, Jergens AE, Duncan RB, Leib MS, McCracken MD, DeNovo RC, Helman RG, Slater MR, Harbison JL. Interobserver variation among histopathologic evaluations of intestinal tissues from dogs and cats. Journal of the American Veterinary Medical Association 220, 1177-82, 2002
110. Wilson SC, Thomson-Kerr K, Houston DM. Hypereosinophilic syndrome in a cat. Canadian Veterinary Journal 37, 679-80, 1996