The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes

Genes and Development

Volumn 15, Issue 14, 2001, Pages 1845-1858

  Schramke, Vera ^a   Neecke, Holger ^b   Brevet, Vanessa ^c   Corda, Yves ^a   Lucchini, Giovanna ^b   Longhese, Maria Pia ^b   Gilson, Eric ^c   Géli, Vincent ^a  

^a CNRS   (France)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c Univ Claude Bernard   (France)

Author keywords

Checkpoint; DNA repair; Gene silencing; Phosphorylation; RPA; SET domain; Telomere

Indexed keywords

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMATIN STRUCTURE; DNA DAMAGE; DNA REPAIR; GENE INDUCTION; GENE MUTATION; GENE SILENCING; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TELOMERE; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; RADIATION RESPONSE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSACTIVATION; ULTRAVIOLET RADIATION;

ANIMALIA;

CELL CYCLE PROTEIN; DNA BINDING PROTEIN; FUNGAL PROTEIN; MEC1 PROTEIN, S CEREVISIAE; MEC3 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; RAD53 PROTEIN, S CEREVISIAE; REPLICATION PROTEIN A; SACCHAROMYCES CEREVISIAE PROTEIN; SET1 PROTEIN, S CEREVISIAE; SIGNAL PEPTIDE; TEL1 PROTEIN, FUNGAL; TEL1 PROTEIN, S CEREVISIAE; TRANSCRIPTION FACTOR;

CELL CYCLE PROTEINS; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FUNGAL PROTEINS; GENE SILENCING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, GENETIC; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; REPLICATION PROTEIN A; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; ULTRAVIOLET RAYS;

EID: 0035878060     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.193901     Document Type: Article

References (47)

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