Expression of the activated (Y501-F501) hck tyrosine kinase in 32Dcl3 myeloid cells prolongs survival in the absence of IL-3 and blocks granulocytic differentiation in response to G-CSF

Journal of Leukocyte Biology

Volumn 60, Issue 5, 1996, Pages 667-673

  English, B Keith ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Hematopoietic cell kinase; Retroviral vectors; src family

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; HEMATOPOIETIC CELL KINASE; INTERLEUKIN 3; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; MOUSE; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; RETROVIRUS;

ANIMALIA; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 0029840978     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.60.5.667     Document Type: Article

References (55)

1. Isfort, R., Huhn, R. D., Frackelton, A. R., Jr., Ihle, J. N. (1988) Stimulation of factor-dependent myeloid cell lines with interleukin 3 induces tyrosine phosphorylation of several cellular substrates. J. Biol. Chem. 263, 19203-19209.
2. Kanakura, Y., Druker, B., Cannistra, S. A., Furukawa, Y., Torimoto, Y., Griffin, J. D. (1990) Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins. Blood 76, 706-715.
3. Hayashida, K., Kitamura, T., German, D. M., Arai, K., Yokota, T., Miyajima, A. (1990) Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc. Natl. Acad. Sci., USA 87, 9655-9659.
4. Weinstein, S. L., Gold, M. R., De Franco, A. L. (1991) Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages. Proc. Natl. Acad. Sci. USA 88, 4148-4152.
5. English, B. K., Ihle, J. N., Myracle, A., Yi, T. (1993) Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages. J. Exp. Med. 178, 1017-1022.
6. Perlmutter, R. M., Marth, J. D., Ziegler, S. F., Garvin, A. M., Pawar, S., Cooke, M. P., Abraham, K. M. (1989) Specialized protein tyrosine kinase proto-oncogenes in hematopoietic cells. Biochim. Biophys. Acta 948, 245-262.
7. Eiseman, E., Bolen, J. B. (1990) Src-related tyrosine protein kinases as signaling components in hematopoietic cells. Cancer Cells 2, 303-310.
8. Kypta, R. M., Goldberg, Y., Ulug, E. T., Courtneidge, S. A. (1990) Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62, 481-492.
9. Ziegler, S. F., Marth, J. D., Lewis, D. B., Perlmutter, R. M. (1987) Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin. Mol. Cell. Biol. 7, 2276-2285.
10. Quintrell, N., Lebo, R., Varmus, H., Bishop, J. M., Pettenati, M. J., Le Beau, M. M., Diaz, M. O., Rowley, J. D. (1987) Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells. Mol. Cell. Biol. 7, 2267-2275.
11. Holtzman, D. A., Cook, W. D., Dunn, A. R. (1987) Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells. Proc. Natl. Acad. Sci. USA 84, 8325-8329.
12. Yi, T. L., Willman, C. L. (1989) Cloning of the murine c-fgr proto-oncogene cDNA and induction of c-fgr expression by proliferation and activation factors in normal bone marrow-derived monocytic cells. Oncogene 4, 1081-1087.
13. Willman, C. L., Stewart, C. C., Longacre, T. L., Head, D. R., Habbersett, R., Ziegler, S. F., Perlmutter, R. M. (1991) Expression of the c-fgr and hck protein-tyrosine kinases in acute myeloid leukemic blasts is associated with early commitment and differentiation events in the monocytic and granulocytic lineages. Blood 77, 726-734.
14. Lichtenberg, U., Quintrell, N., Bishop, J. M. (1992) Human protein-tyrosine kinase gene HCK: expression and structural analysis of the promoter region. Oncogene 7, 849-858.
15. Beaty, C. D., Franklin, T. L., Uehara, Y., Wilson, C. B. (1994) Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction. Eur. J. Immunol. 24, 1278-1284.
16. Lowell, C. A., Soriano, P., Varmus, H. E. (1994) Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes Dev. 8, 387-398.
17. Durden, D. L., Kim, H. M., Calore, B., Liu, Y. (1995) The Fc gamma RI receptor signals through the activation of hck and MAP kinase. J. Immunol. 154, 4039-4047.
18. Greenberger, J. S., Sakakeeny, M. A., Humphries, R. K., Eaves, C. J., Eckner, R. J. (1983) Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines. Proc. Natl. Acad. Sci. USA 80, 2931-2935.
19. Metcalf, D. (1985) Multi-CSF-dependent colony formation by cells of a murine hemopoietic cell line: specificity and action of multi-CSF. Blood 65, 357-362.
20. Valtieri, M., Tweardy, D. J., Caracciolo, D., Johnson, K., Mavilio, F., Altmann, S., Santoli, D., Rovera, G. (1987) Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line. J. Immunol. 138, 3829-3835.
21. Askew, D. S., Ashmun, R. A., Simmons, B. C., Cleveland, J. L. (1991) Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6, 1915-1922.
22. Ihle, J. N., Keller, J., Henderson, L., Klein, F., Palaszynski, E. W. (1982) Procedures for the purification of interleukin-3 to homogeneity. J. Immunol. 129, 2431-2436.
23. Pierce, J. H., Di Marco, E., Cox, G. W., Lombardi, D., Ruggiero, M., Varesio, L., Wang, L. M., Choudhury, G. G., Sakaguchi, A. Y., Di Fiore, P. P., et al. (1990) Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA. Proc. Natl. Acad. Sci. USA 87, 5613-5617.
24. Marth, J. D., Lewis, D. B., Cooke, M. P., Mellins, E. D., Gearn, M. E., Samelson, L. E., Wilson, C. B., Miller, A. D., Perlmutter, R. M. (1989) Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck). J. Immunol. 142, 2430-2437.
25. Ziegler, S. F., Levin, S. D., Perlmutter, R. M. (1989) Transformation of NIH 3T3 fibroblasts by an activated form of p59hck. Mol. Cell. Biol. 9, 2724-2727.
26. Mann, R., Mulligan, R. C., Baltimore, D. (1983) Construction of a retroviral packaging mutant and its use to produce helper-free defective retroviruses. Cell 33, 153-159.
27. Maniatis, T., Fritsch, E. F., Sambrook, J. (1982) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 187-209.
28. Lewis, D. B., Larsen, A., Wilson, C. B. (1986) Reduced interferon-gamma mRNA levels in human neonates. J. Exp. Med. 163, 1018-1023.
29. Overell, R. W., Watson, J. D., Gallis, B., Weisser, K. E., Cosman, D., Widmer, M. B. (1987) Nature and specificity of lymphokine independence induced by a selectable retroviral vector expressing v-src. Mol. Cell. Biol. 7, 3394-3401.
30. Pierce, J. H., Di Fiore, P. P., Aaronson, S. A., Potter, M., Pumphrey, J., Scott, A., Ihle, J. N. (1985) Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell 41, 685-693.
31. Cook, W. D., Nicola, N. A., Burgess, A. W. (1985) Malignant transformation of a growth factor dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism. Cell 41, 677-685.
32. Cleveland, J. L., Dean, M., Rosenberg, N., Wang, J. Y., Rapp, U. R. (1989) Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. Mol. Cell. Biol. 9, 5685-5695.
33. Anderson, S. M., Carroll, P. M., Lee, F. D. (1990) Abrogation of IL-3 dependent growth requires a functional v-src gene product: evidence for an autocrine growth cycle. Oncogene 5, 317-325.
34. Watson, J. D., Esze, M., Overall, R., Conlon, P., Widmer, M., Gillis, S. (1987) Effect on infection with murine recombinant retroviruses containing the v-src oncogene on interleukin 2 and interleukin 3-dependent growth states. J. Immunol. 139, 123-129.
35. Kreider, B. L., Phillips, P. D., Prystowsky, M. B., Shirsat, N., Pierce, J. H., Tushinski, R., Rovera, G. (1990) Induction of the granulocyte-macrophage colony-stimulating factor (CSF) receptor by granulocyte CSF increases the differentiative options of a murine hematopoietic progenitor cell. Mol. Cell. Biol. 10, 4846-4853.
36. Sawyers, C. L., Denny, C. T., Witte, O. N. (1991) Leukemia and the disruption of normal hematopoiesis. Cell 64, 337-350.
37. Veillette, A., Bookman, M. A., Horak, E. M., Bolen, J. B. (1988) The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. Cell 55, 301-308.
38. Shaw, A. S., Amrein, K. E., Hammond, C., Stern, D. F., Sefton, B. M., Rose, J. K. (1989) The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain. Cell 59, 627-636.
39. Turner, J. M., Brodsky, M. H., Irving, B. A., Levin, S. D., Perlmutter, R. M., Littman, D. R. (1990) Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell 60, 755-765.
40. Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A., Levin, S. D., Perlmutter, R. M., Taniguchi, T. (1991) Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science 252, 1523-1528.
41. Samelson, L. E., Phillips, A. F., Luong, E. T., Klausner, R. D. (1990) Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. Proc. Natl. Acad. Sci. USA 87, 4358-4362.
42. Cooke, M. P., Abraham, K. M., Forbush, K. A., Perlmutter, R. M. (1991) Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn). Cell 65, 281-291.
43. Yamanashi, Y., Fukui, Y., Wongsasant, B., Kinoshita, Y., Ichimori, Y., Toyoshima, K., Yamamoto, T. (1992) Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling. Proc. Natl. Acad. Sci. USA 89, 1118-1122.
44. Eiseman, E., Bolen, J. B. (1992) Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases. Nature 355, 78-80.
45. Zamoyska, R., Derham, P., Gorman, S. D., von Hoegen, P., Bolen, J. B., Veillette, A., Parnes, J. R. (1989) Inability of CD8 alpha′ polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo. Nature 342, 278-281.
46. Veillette, A., Bookman, M. A., Horak, E. M., Samelson, L. E., Bolen, J. B. (1989) Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck. Nature 338, 257-259.
47. Appleby, M. W., Gross, J. A., Cooke, M. P., Levin, S. D., Qian, X., Perlmutter, R. M. (1992) Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70, 751-763.
48. Stein, P. L., Lee, H. M., Rich, S., Soriano, P (1992) pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70, 741-750.
49. Lock, P., Ralph, S., Stanley, E., Boulet, I., Ramsay, R., Dunn, A. R. (1991) Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization. Mol. Cell. Biol. 11, 4363-4370.
50. Anderson, S. M., Jorgensen, B. (1995) Activation of src-related tyrosine kinases by IL-3. J. Immunol. 155, 1660-1670.
51. Lieschke, G. J., Grail, D., Hodgson, G., Metcalf, D, Stanley, D., Cheers, C, Fowler, K. J., Basu, S., Shan, Y. F., Dunn, A. R. (1994) Mice lacking in granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood 84, 1737-1746.
52. Ziegler, S. F., Bird, T. A., Morella, K. K., Mosley, B., Gearing, D. P., Baumann, H. (1993) Distinct regions of the human granuloctye-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction. Mol. Cell. Biol. 13, 2384-2390.
53. Corey, S. J., Burkhardt, A. L., Bolen, J. B., Geahlen, R. L., Tkatch, L. S., Tweardy, D. J. (1994) Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. Proc. Natl. Acad. Sci USA 91, 4683-4687.
54. Nicholson, S. E., Novak, U., Ziegler, S. F., Layton, J. E. (1995) Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat 3, and P42/p44 MAPK. Blood 86, 3698-3704.
55. Tweardy, D. J., Wright, T. M., Ziegler, S. F., Baumann, H., Chakraborty, A., White, S. M., Dyer, K. F., Rubin, K. A. (1995) Granulocyte colony-stimulating factor rapidly activates a distinct STAT-like protein in normal myeloid cells. Blood 86, 4409-4416.