-
1
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Farinas I. et al. (2000) Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25, 239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
-
2
-
-
0037127216
-
Tubulin seeds α-synuclein fibril formation
-
Alim M. A., Hossain M. S., Arima K. et al. (2002) Tubulin seeds α-synuclein fibril formation. J. Biol. Chem. 277, 2112-2117.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2112-2117
-
-
Alim, M.A.1
Hossain, M.S.2
Arima, K.3
-
3
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V., Rizzu P., van Baren M. J. et al. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299, 256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
-
4
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D. R., Ratovitski T., Van Lare J., Lee M. K., Gonzales V., Jenkins N. A., Copeland N. G., Price D. L. and Sisodia S. S. (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
5
-
-
0032126386
-
Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice
-
Borchelt D. R., Wong P. C., Becher M. W. et al. (1998) Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiol. Dis. 5, 27-35.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 27-35
-
-
Borchelt, D.R.1
Wong, P.C.2
Becher, M.W.3
-
6
-
-
0035163412
-
The solubility of α-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease
-
Campbell B. C., McLean C. A., Culvenor J. G., Gai W. P., Blumbergs P. C., Jakala P., Beyreuther K., Masters C. L. and Li Q. X. (2001) The solubility of α-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease. J. Neurochem. 76, 87-96.
-
(2001)
J. Neurochem.
, vol.76
, pp. 87-96
-
-
Campbell, B.C.1
McLean, C.A.2
Culvenor, J.G.3
Gai, W.P.4
Blumbergs, P.C.5
Jakala, P.6
Beyreuther, K.7
Masters, C.L.8
Li, Q.X.9
-
7
-
-
0033215063
-
Synucleins in synaptic plasticity and neurodegenerative disorders
-
Clayton D. F. and George J. M. (1999) Synucleins in synaptic plasticity and neurodegenerative disorders. J. Neurosci. Res. 58, 120-129.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 120-129
-
-
Clayton, D.F.1
George, J.M.2
-
8
-
-
84940364788
-
α-synuclein and the lewy body disorders
-
Dickson D. W. (2001) α-Synuclein and the lewy body disorders. Curr. Opin. Neurol. 14, 423-432.
-
(2001)
Curr. Opin. Neurol.
, vol.14
, pp. 423-432
-
-
Dickson, D.W.1
-
9
-
-
0033678217
-
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies
-
Duda J. E., Giasson B. I., Chen Q. et al. (2000a) Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am. J. Pathol. 157, 1439-1445.
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1439-1445
-
-
Duda, J.E.1
Giasson, B.I.2
Chen, Q.3
-
10
-
-
0033800039
-
Immunohistochemical and biochemical studies demonstrate a distinct profile of α-synuclein permutations in multiple system atrophy
-
Duda J. E., Giasson B. I., Gur T. L. et al. (2000b) Immunohistochemical and biochemical studies demonstrate a distinct profile of α-synuclein permutations in multiple system atrophy. J. Neuropathol. Exp. Neurol. 59, 830-841.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, pp. 830-841
-
-
Duda, J.E.1
Giasson, B.I.2
Gur, T.L.3
-
11
-
-
0003148419
-
Parkinsonism
-
(Rowland L. P., ed.). Lippincott Williams & Wilkins, New York
-
Fahn S. and Przedborski S. (2000) Parkinsonism. In: Merritt's Neurology (Rowland L. P., ed.), pp. 679-695. Lippincott Williams & Wilkins, New York.
-
(2000)
Merritt's Neurology
, pp. 679-695
-
-
Fahn, S.1
Przedborski, S.2
-
12
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M. B. and Bender W. W. (2000) A Drosophila model of Parkinson's disease. Nature 404, 394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
13
-
-
0032692501
-
α-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components
-
Gai W. P., Power J. H., Blumbergs P. C., Culvenor J. G. and Jensen P. H. (1999) α-Synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components. J. Neurochem. 73, 2093-2100.
-
(1999)
J. Neurochem.
, vol.73
, pp. 2093-2100
-
-
Gai, W.P.1
Power, J.H.2
Blumbergs, P.C.3
Culvenor, J.G.4
Jensen, P.H.5
-
14
-
-
0033539664
-
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains α-, β-, and γ-synuclein
-
Galvin J. E., Uryu K., Lee V. M. and Trojanowski J. Q. (1999) Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains α-, β-, and γ-synuclein. Proc. Natl Acad. Sci. USA 96, 13450-13455.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13450-13455
-
-
Galvin, J.E.1
Uryu, K.2
Lee, V.M.3
Trojanowski, J.Q.4
-
16
-
-
0036150971
-
The synucleins
-
George J. M. (2002) The synucleins. Genome Biol. 3, 3002.1-3002.6.
-
(2002)
Genome Biol.
, vol.3
, pp. 30021-30026
-
-
George, J.M.1
-
17
-
-
0001477529
-
Songbirds, synelfin, and neurodegenerative disease
-
George J. M. and Clayton D. F. (1998) Songbirds, synelfin, and neurodegenerative disease. Neurosci. News 1, 12-17.
-
(1998)
Neurosci. News
, vol.1
, pp. 12-17
-
-
George, J.M.1
Clayton, D.F.2
-
18
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
-
Giasson B. I., Duda J. E., Murray I. V., Chen Q., Souza J. M., Hurtig H. I., Ischiropoulos H., Trojanowski J. Q. and Lee V. M. (2000) Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions. Science 290, 985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
19
-
-
0037118259
-
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson B. I., Duda J. E., Quinn S. M., Zhang B., Trojanowski J. Q. and Lee V. M. (2002) Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34, 521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
20
-
-
0031576074
-
The awakening of α-synuclein
-
Goedert M. (1997) The awakening of α-synuclein. Nature 388, 232-233.
-
(1997)
Nature
, vol.388
, pp. 232-233
-
-
Goedert, M.1
-
21
-
-
0031789960
-
Lewy body diseases and multiple system atrophy as α -synucleinopathies
-
Goedert M. and Spillantini M. G. (1998) Lewy body diseases and multiple system atrophy as α-synucleinopathies. Mol. Psychiatry 3, 462-465.
-
(1998)
Mol. Psychiatry
, vol.3
, pp. 462-465
-
-
Goedert, M.1
Spillantini, M.G.2
-
22
-
-
0030727581
-
The mechanisms of fast and slow transport in neurons: Identification and characterization of the new kinesin superfamily motors
-
Hirokawa N. (1997) The mechanisms of fast and slow transport in neurons: identification and characterization of the new kinesin superfamily motors. Curr. Opin. Neurobiol. 7, 605-614.
-
(1997)
Curr. Opin. Neurobiol.
, vol.7
, pp. 605-614
-
-
Hirokawa, N.1
-
23
-
-
0016541063
-
The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons
-
Hoffman P. N. and Lasek R. J. (1975) The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons. J. Cell Biol. 66, 351-366.
-
(1975)
J. Cell Biol.
, vol.66
, pp. 351-366
-
-
Hoffman, P.N.1
Lasek, R.J.2
-
24
-
-
0020962034
-
Slowing of the axonal transport of neurofilament proteins during development
-
Hoffman P. N., Lasek R. J., Griffin J. W. and Price D. L. (1983) Slowing of the axonal transport of neurofilament proteins during development. J. Neurosci. 3, 1694-1700.
-
(1983)
J. Neurosci.
, vol.3
, pp. 1694-1700
-
-
Hoffman, P.N.1
Lasek, R.J.2
Griffin, J.W.3
Price, D.L.4
-
25
-
-
0026764984
-
Axonal transport of class II and III β-tubulin: Evidence that the slow component wave represents the movement of only a small fraction of the tubulin in mature motor axons
-
Hoffman P. N., Lopata M. A., Watson D. F. and Luduena R. F. (1992) Axonal transport of class II and III β-tubulin: evidence that the slow component wave represents the movement of only a small fraction of the tubulin in mature motor axons. J. Cell Biol. 119, 595-604.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 595-604
-
-
Hoffman, P.N.1
Lopata, M.A.2
Watson, D.F.3
Luduena, R.F.4
-
26
-
-
0032500599
-
Binding of α-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation
-
Jensen P. H., Nielsen M. S., Jakes R., Dotti C. G. and Goedert M. (1998) Binding of α-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. J. Biol. Chem. 273, 26292-26294.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26292-26294
-
-
Jensen, P.H.1
Nielsen, M.S.2
Jakes, R.3
Dotti, C.G.4
Goedert, M.5
-
27
-
-
0032824809
-
Axonal transport of synucleins is mediated by all rate components
-
Jensen P. H., Li J. Y., Dahlstrom A. and Dotti C. G. (1999) Axonal transport of synucleins is mediated by all rate components. Eur. J. Neurosci. 11, 3369-3376.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3369-3376
-
-
Jensen, P.H.1
Li, J.Y.2
Dahlstrom, A.3
Dotti, C.G.4
-
28
-
-
0035191413
-
Selective insolubility of α-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model
-
Kahle P. J., Neumann M., Ozmen L. et al. (2001) Selective insolubility of α-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model. Am. J. Pathol. 159, 2215-2225.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 2215-2225
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
-
29
-
-
0036550101
-
Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system
-
Kirik D., Rosenblad C., Burger C., Lundberg C., Johansen T. E., Muzyczka N., Mandel R. J. and Bjorklund A. (2002) Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system. J. Neurosci. 22, 2780-2791.
-
(2002)
J. Neurosci.
, vol.22
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
Muzyczka, N.6
Mandel, R.J.7
Bjorklund, A.8
-
30
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y. and Shimizu N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
31
-
-
0346460948
-
Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis
-
Krishnan S., Chi E. Y., Wood S. J. et al. (2003) Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis. Biochemistry 42, 829-837.
-
(2003)
Biochemistry
, vol.42
, pp. 829-837
-
-
Krishnan, S.1
Chi, E.Y.2
Wood, S.J.3
-
32
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger R., Kuhn W., Muller T. et al. (1998) Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat. Genet 18, 106-108.
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
-
33
-
-
0027212960
-
The maximum rate of neurofilament transport in axons: A view of molecular transport mechanisms continuously engaged
-
Lasek R. J., Paggi P. and Katz M. J. (1993) The maximum rate of neurofilament transport in axons: a view of molecular transport mechanisms continuously engaged. Brain Res. 616, 58-64.
-
(1993)
Brain Res.
, vol.616
, pp. 58-64
-
-
Lasek, R.J.1
Paggi, P.2
Katz, M.J.3
-
34
-
-
10544229795
-
Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues
-
Lee M. K., Slunt H. H., Martin L. J., Thinakaran G., Kim G., Gandy S. E., Seeger M., Koo E., Price D. L. and Sisodia S. S. (1996) Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. J. Neurosci. 16, 7513-7525.
-
(1996)
J. Neurosci.
, vol.16
, pp. 7513-7525
-
-
Lee, M.K.1
Slunt, H.H.2
Martin, L.J.3
Thinakaran, G.4
Kim, G.5
Gandy, S.E.6
Seeger, M.7
Koo, E.8
Price, D.L.9
Sisodia, S.S.10
-
35
-
-
0035066885
-
Direct binding and functional coupling of α-synuclein to the dopamine transproters accelerate dopamine induced apoptosis
-
Lee F. J. S., Liu F., Pristupa Z. B. and Niznik H. B. (2001) Direct binding and functional coupling of α-synuclein to the dopamine transproters accelerate dopamine induced apoptosis. FASEB. J. 15, 926.
-
(2001)
FASEB J.
, vol.15
, pp. 926
-
-
Lee, F.J.S.1
Liu, F.2
Pristupa, Z.B.3
Niznik, H.B.4
-
36
-
-
0037173006
-
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53→Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
-
Lee M. K., Stirling W., Xu Y. et al. (2002) Human α -synuclein-harboring familial Parkinson's disease-linked Ala-53→Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice. Proc. Natl Acad. Sci. USA 99, 8968-8973.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
-
37
-
-
0034759869
-
α-synuclein in familial Alzheimer disease: Epitope mapping parallels dementia with Lewy bodies and Parkinson disease
-
Lippa C. F., Schmidt M. L., Lee V. M. and Trojanowski J. Q. (2001) α-Synuclein in familial Alzheimer disease: epitope mapping parallels dementia with Lewy bodies and Parkinson disease. Arch. Neurol. 58, 1817-1820.
-
(2001)
Arch. Neurol.
, vol.58
, pp. 1817-1820
-
-
Lippa, C.F.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
-
38
-
-
0036679197
-
α-synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
-
Lo B. C., Ridet J. L., Schneider B. L., Deglon N. and Aebischer P. (2002) α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc. Natl Acad. Sci. USA 99, 10813-10818.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10813-10818
-
-
Lo, B.C.1
Ridet, J.L.2
Schneider, B.L.3
Deglon, N.4
Aebischer, P.5
-
39
-
-
0034654503
-
Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: Distinct transport rates of different isoforms
-
Ma D., Himes B. T., Shea T. B. and Fischer I. (2000) Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: distinct transport rates of different isoforms. J. Neurosci. 20, 2112-2120.
-
(2000)
J. Neurosci.
, vol.20
, pp. 2112-2120
-
-
Ma, D.1
Himes, B.T.2
Shea, T.B.3
Fischer, I.4
-
40
-
-
0024462479
-
Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging
-
McQuarrie I. G., Brady S. T. and Lasek R. J. (1989) Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging. Neurobiol. Aging 10, 359-365.
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 359-365
-
-
McQuarrie, I.G.1
Brady, S.T.2
Lasek, R.J.3
-
41
-
-
0023722437
-
Synuclein: A neuron-specific protein localized to the nucleus and pre-synaptic nerve terminal
-
Maroteaux L., Campanelli J. T. and Scheller R. H. (1988) Synuclein: a neuron-specific protein localized to the nucleus and pre-synaptic nerve terminal. J. Neurosci. 8, 2804-2815.
-
(1988)
J. Neurosci.
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
42
-
-
0029807823
-
Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport
-
Marszalek J. R., Williamson T. L., Lee M. K., Xu Z., Hoffman P. N., Becher M. W., Crawford T. O. and Cleveland D. W. (1996) Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport. J. Cell Biol. 135, 711-724.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 711-724
-
-
Marszalek, J.R.1
Williamson, T.L.2
Lee, M.K.3
Xu, Z.4
Hoffman, P.N.5
Becher, M.W.6
Crawford, T.O.7
Cleveland, D.W.8
-
43
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
Masliah E., Rockenstein E., Veinbergs I., Mallory M., Hashimoto M., Takeda A., Sagara Y., Sisk A. and Mucke L. (2000) Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders. Science 287, 1265-1269.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
44
-
-
0036855635
-
Misfolded proteinase K-resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies
-
Neumann M., Kahle P. J., Giasson B. I. et al. (2002) Misfolded proteinase K-resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies. J. Clin. Invest. 110, 1429-1439.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1429-1439
-
-
Neumann, M.1
Kahle, P.J.2
Giasson, B.I.3
-
45
-
-
0015775646
-
Effect of maturation and aging on the rate of fast axoplasmic transport in mammalian nerve
-
Ochs S. (1973) Effect of maturation and aging on the rate of fast axoplasmic transport in mammalian nerve. Prog. Brain Res. 40, 349-362.
-
(1973)
Prog. Brain Res.
, vol.40
, pp. 349-362
-
-
Ochs, S.1
-
46
-
-
0035887860
-
Induction of α-synuclein aggregation by intracellular nitrative insult
-
Paxinou E., Chen Q., Weisse M., Giasson B. I., Norris E. H., Rueter S. M., Trojanowski J. Q., Lee V. M. and Ischiropoulos H. (2001) Induction of α-synuclein aggregation by intracellular nitrative insult. J. Neurosci. 21, 8053-8061.
-
(2001)
J. Neurosci.
, vol.21
, pp. 8053-8061
-
-
Paxinou, E.1
Chen, Q.2
Weisse, M.3
Giasson, B.I.4
Norris, E.H.5
Rueter, S.M.6
Trojanowski, J.Q.7
Lee, V.M.8
Ischiropoulos, H.9
-
47
-
-
0037092442
-
A role for α-synuclein in the regulation of dopamine biosynthesis
-
Perez R. G., Waymire J. C., Lin E., Liu J. J., Guo F. and Zigmond M. J. (2002) A role for α-synuclein in the regulation of dopamine biosynthesis. J. Neurosci. 22, 3090-3099.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3090-3099
-
-
Perez, R.G.1
Waymire, J.C.2
Lin, E.3
Liu, J.J.4
Guo, F.5
Zigmond, M.J.6
-
48
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M. H., Lavedan C., Leroy E. et al. (1997) Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
49
-
-
0034609561
-
Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse α-synuclein
-
Rochet J. C., Conway K. A. and Lansbury P. T. Jr (2000) Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse α-synuclein. Biochemistry 39, 10619-10626.
-
(2000)
Biochemistry
, vol.39
, pp. 10619-10626
-
-
Rochet, J.C.1
Conway, K.A.2
Lansbury Jr., P.T.3
-
50
-
-
0034666282
-
Neurofilaments are transported rapidly but intermittently in axons: Implications for slow axonal transport
-
Roy S., Coffee P., Smith G., Liem R. K. H., Brady S. T. and Black M. M. (2000) Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport. J. Neurosci. 20, 6849-6861.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6849-6861
-
-
Roy, S.1
Coffee, P.2
Smith, G.3
Liem, R.K.H.4
Brady, S.T.5
Black, M.M.6
-
51
-
-
0036468394
-
Slow axonal transport: Fast motors in the slow lane
-
Shah J. V. and Cleveland D. W. (2002) Slow axonal transport: fast motors in the slow lane. Curr. Opin. Cell Biol. 14, 58-62.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 58-62
-
-
Shah, J.V.1
Cleveland, D.W.2
-
52
-
-
0035510709
-
Kinesin, dynein and neurofilament transport
-
Shea T. B. and Flanagan L. A. (2001) Kinesin, dynein and neurofilament transport. Trends Neurosci. 24, 644-648.
-
(2001)
Trends Neurosci.
, vol.24
, pp. 644-648
-
-
Shea, T.B.1
Flanagan, L.A.2
-
53
-
-
0034674652
-
Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
-
Souza J. M., Giasson B. I., Chen Q., Lee V. M. and Ischiropoulos H. (2000) Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. J. Biol. Chem. 275, 18344-18349.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18344-18349
-
-
Souza, J.M.1
Giasson, B.I.2
Chen, Q.3
Lee, V.M.4
Ischiropoulos, H.5
-
54
-
-
0030882856
-
α-synuclein in Lewy bodies
-
Spillantini M. G., Schmidt M. L., Lee V. M., Trojanowski J. Q., Jakes R. and Goedert M. (1997) α-Synuclein in Lewy bodies. Nature 388, 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
55
-
-
0032568534
-
α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini M. G., Crowther R. A., Jakes R., Hasegawa M. and Goedert M. (1998) α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl Acad. Sci. USA 95, 6469-6473.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
56
-
-
0019965340
-
Axoplasmic transport in aged rats
-
Stromska D. P. and Ochs S. (1982) Axoplasmic transport in aged rats. Neurol. 77, 215-224.
-
(1982)
Neurol.
, vol.77
, pp. 215-224
-
-
Stromska, D.P.1
Ochs, S.2
-
57
-
-
0026045905
-
Maturation and aging of the axonal cytoskeleton: Biochemical analysis of transported tubulin
-
Tashiro T. and Komiya Y. (1991) Maturation and aging of the axonal cytoskeleton: biochemical analysis of transported tubulin. J. Neurosci. Res. 30, 192-200.
-
(1991)
J. Neurosci. Res.
, vol.30
, pp. 192-200
-
-
Tashiro, T.1
Komiya, Y.2
-
58
-
-
0029788486
-
Differential axonal transport of soluble and insoluble τ in the rat sciatic nerve
-
Tashiro T., Sun X. Y., Tsuda M. and Komiya Y. (1996) Differential axonal transport of soluble and insoluble τ in the rat sciatic nerve. J. Neurochem. 67, 1566-1574.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1566-1574
-
-
Tashiro, T.1
Sun, X.Y.2
Tsuda, M.3
Komiya, Y.4
-
59
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer's disease
-
Ueda K., Fukushima H., Masliah E. et al. (1993) Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer's disease. Proc. Natl Acad. Sci. USA 90, 11282-11286.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
-
60
-
-
0034663176
-
Neuropathology in mice expressing human α-synuclein
-
Van der Putten H., Wiederhold K. H., Probst A. et al. (2000) Neuropathology in mice expressing human α-synuclein. J. Neurosci. 20, 6021-6029.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6021-6029
-
-
Van Der Putten, H.1
Wiederhold, K.H.2
Probst, A.3
-
61
-
-
0033776708
-
Rapid movement of axonal neurofilaments interrupted by prolonged pauses
-
Wang L., Ho C. L., Sun D., Liem R. K. and Brown A. (2000) Rapid movement of axonal neurofilaments interrupted by prolonged pauses. Nat. Cell Biol. 2, 137-141.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 137-141
-
-
Wang, L.1
Ho, C.L.2
Sun, D.3
Liem, R.K.4
Brown, A.5
-
62
-
-
0033366384
-
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
-
Williamson T. L. and Cleveland D. W. (1999) Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat. Neurosci. 2, 50-56.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 50-56
-
-
Williamson, T.L.1
Cleveland, D.W.2
|