α-synuclein in familial Alzheimer disease: Epitope mapping parallels dementia with Lewy bodies and Parkinson disease

Archives of Neurology

Volumn 58, Issue 11, 2001, Pages 1817-1820

  Lippa, Carol F ^a   Schmidt, M Luise ^b   Lee, Virginia M Y ^b   Trojanowski, John Q ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; ANTIBODY; EPITOPE;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; EPITOPE MAPPING; GENE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEWY BODY; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0034759869     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.58.11.1817     Document Type: Article

References (11)

1. Lewy bodies in Alzheimer's disease: A neuropathological review of 145 cases using α-synuclein immunohistochemistry
2. Lewy bodies contain altered α-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes
3. Antibodies to α-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease
4. Immunohistochemical and biochemical studies demonstrate a distinct profile of α-synuclein permutations in multiple system atrophy
5. Diagnostic criteria for neuropathologic assessment of Alzheimer's disease
6. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
7. Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity
8. α-synuclein is developmentally expressed in cultured rat brain oligodendrocytes
9. Diffuse Lewy body disease
10. Pattern of brain destruction in Parkinson's and Alzheimer's diseases
11. Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of AIzheimer's disease and Lewy body disorders