Molecular dynamics on complexes of ras-p21 and its inhibitor protein, rap-1a, bound to the ras-binding domain of the raf-p74 protein: Identification of effector domains in the raf protein

Journal of Protein Chemistry

Volumn 16, Issue 6, 1997, Pages 619-629

  Chen, James M ^a   Monaco, Regina ^b   Manolatos, Spero ^c   Brandt Rauf, Paul W ^d   Friedman, Fred K ^e   Pincus, Matthew R ^c,f  

^a DUPONT COMPANY   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Average structures; Effector domains; Molecular dynamics; Raf 1A and ras p21 complexes with raf; Ras binding domain of raf; Signal transduction

Indexed keywords

PROTEIN P21; RAF PROTEIN;

ARTICLE; BINDING SITE; MITOGENICITY; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

GTP-BINDING PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); RAP GTP-BINDING PROTEINS;

EID: 53249121746     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026322924424     Document Type: Article

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