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Volumn 7, Issue 7, 1997, Pages 897-902

A novel series of matrix metalloproteinase inhibitors for the treatment of inflammatory disorders

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ISOENZYME; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE; TRIPEPTIDE DERIVATIVE;

EID: 0030936876     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00125-X     Document Type: Article
Times cited : (38)

References (22)
  • 7
    • 0003780442 scopus 로고
    • Hansch, C., Sammes, P. G., Taylor J. B., Eds.; Pergamon Press: New York
    • (g) Rich, D. H. In Comprehensive Medicinal Chemistry; Hansch, C., Sammes, P. G., Taylor J. B., Eds.; Pergamon Press: New York, 1990.
    • (1990) Comprehensive Medicinal Chemistry
    • Rich, D.H.1
  • 9
    • 0027025213 scopus 로고
    • Matrix Supplement Birkedal-Hansen, H., Werb, Z., Welgus, H. G., Van Wart, H. E., Eds.; Gustav Fischer Verlag: New York
    • Nagase, H.; Barrett, A. J.; Woessner, J. F. In Matrix Metalloproteinases and Inhibitors, Matrix Supplement No 1; Birkedal-Hansen, H., Werb, Z., Welgus, H. G., Van Wart, H. E., Eds.; Gustav Fischer Verlag: New York, 1992; pp 421-424.
    • (1992) Matrix Metalloproteinases and Inhibitors , vol.1 , pp. 421-424
    • Nagase, H.1    Barrett, A.J.2    Woessner, J.F.3
  • 15
    • 0027030103 scopus 로고
    • Ellis, G. P.; Luscombe, D. K., Eds.; Elsevier Science Publishers B. V.: The Netherlands
    • For recent reviews of small-molecule synthetic inhibitors see (a) Schwartz, M. A.; Van Wart, H. E. In Progress in Medicinal Chemistry; Ellis, G. P.; Luscombe, D. K., Eds.; Elsevier Science Publishers B. V.: The Netherlands 1992; Vol 29
    • (1992) Progress in Medicinal Chemistry , vol.29
    • Schwartz, M.A.1    Van Wart, H.E.2
  • 18
    • 0019778366 scopus 로고
    • For general reviews of thiol-based ligands, see reference 5, above. Some examples of mercaptoacyl MMP inhibitors similar to 1 are known in the literature. See ref 1(c), above, and Gray, R. D.; Sanelli, H. H.; Spatola, A. F. Biochem. Biophys. Res. Commun., 1981, 101, 1251-1258.
    • (1981) Biochem. Biophys. Res. Commun. , vol.101 , pp. 1251-1258
    • Gray, R.D.1    Sanelli, H.H.2    Spatola, A.F.3
  • 19
    • 0343087824 scopus 로고    scopus 로고
    • 1H NMR and mass spectroscopy
    • 1H NMR and mass spectroscopy.
  • 20
    • 0026505650 scopus 로고
    • 50 values quoted are geometric means of at least three determinations. They were determined using fluorimetric assays for the MMP enzyme inhibition, based on the procedure described by Knight, G. C.; Willenbrock, F.; Murphy, G. FEBS 1992, 296, 263-266.
    • (1992) FEBS , vol.296 , pp. 263-266
    • Knight, G.C.1    Willenbrock, F.2    Murphy, G.3
  • 22
    • 0038667028 scopus 로고
    • For details of the Adjuvant Arthritic Rat model of arthritis, see Newbold, B. B. Brit. J. Pharmacol. 1963, 21, 127.
    • (1963) Brit. J. Pharmacol. , vol.21 , pp. 127
    • Newbold, B.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.