Tumor necrosis factor α augments amyloid β protein (25-35) induced apoptosis in human cells

Neuroscience Letters

Volumn 238, Issue 1-2, 1997, Pages 17-20

  Blasko, I ^a   Schmitt, T L ^a   Steiner, E ^b   Trieb, K ^a   Grubeck Loebenstein, B ^a  

^a Inst Biomed Aging Res Austrian A   (Austria)

^b 'Bezirkskrankenhaus' Hall ^*  (Austria)

Author keywords

Alzheimer's disease; Amyloid protein; Amyloid protein (25 35); Apoptosis; Cytokines; DU 145; Kidney cells; SKN SH; Thyroid cells; Tumor necrosis factor

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ARTICLE; CELL CULTURE; CELL TRANSFORMATION; CYTOTOXICITY; DISEASE SEVERITY; HUMAN; HUMAN CELL; KIDNEY CELL; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS;

AMYLOID BETA-PROTEIN; APOPTOSIS; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; HUMANS; KIDNEY; MALE; NEUROBLASTOMA; PEPTIDE FRAGMENTS; PROSTATIC NEOPLASMS; SPECIES SPECIFICITY; THYROID GLAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031455983     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00845-8     Document Type: Article

References (22)

1. 2+-accumulation. Proc. Natl. Acad. Sci. USA. 92:1995;9328-9332.
2. Bruce A.J., Boling W., Kindy M.S., Peschon J., Kraemer P.J., Carpenter M.K., Holtsberg F.W., Mattson M.P. Altered neuronal and microglial responses to brain injury in mice lacking TNF receptors. Nature Med. 2:1996;788-794.
3. Chao C.C., Hu S. Tumor necrosis factor-α potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev. Neurosci. 16:1994;172-179.
4. Cheng B., Christakos S., Mattson M.P. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron. 12:1994;139-153.
5. Eddy L.J., Goeddel D.V., Wong G.H. Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury. Biochem. Biophys. Res. Commun. 184:1992;1056-1059.
6. Griffin W.S., Sheng J.G., Roberts G.W., Mrak R.E. Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54:1995;276-281.
7. Grubeck-Loebenstein B., Lechner H., Trieb K. Long-term in vitro growth of human T cell clones: can postmitotic 'senescent' cell populations be defined? Int. Arch. Allergy Immunol. 104:1994;232-239.
8. Iversen L.L., Mortishire-Smith R.J., Pollack S.J., Shearman M.S. The toxicity in vitro of β-amyloid protein. Biochem. J. 311:1995;1-16.
9. Louis J.C., Magal E., Takayama S., Varon S.S. CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death. Science. 259:1993;689-692.
10. Klegeris A., Walker D.G., McGeer P.L. Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α Brain Res. 747:1997;114-121.
11. Mattson M.P., Barger S.W., Furukawa K., Bruce A.J., Wyss-Coray T., Mark R.J., Mucke L. Cellular signaling of TGFβ, TNF-α and βAPP in brain injury responses and Alzheimer's disease. Brain Res. Rev. 23:1997;47-61.
12. McGeer P.L., McGeer E.G. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Rev. 21:1995;195-218.
13. McGeer P.L., Schulzer M., McGeer E.G. Arthritis and antiinflammatory agents as possible protective factors for Azheimer's disease: a review of 17 epidemiologic studies. Neurology. 47:1996;425-432.
14. Meda L., Cassatella M.A., Szendrei G.I., Otvos L. Jr., Baron P., Villalba M., Ferrari D., Rossi F. Activation of microglial cells by β-amyloid protein and interferon-γ Nature. 374:1995;647-650.
15. Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods. 139:1991;271-279.
16. Rothwell N.J., Luheshi G.N. Brain TNF: damage limitation or damaged reputation? Nature Med. 7:1996;746-747.
17. Schmitt T.L., Steiner E., Klingler P., Lassman H., Grubeck-Loebenstein B. Thyroid epithelial cells produce large amounts of the Alzheimer β-amyloid precursor protein (APP) and generate potentially amyloidogenic APP fragments. J. Clin. Endocrinol. Metab. 12:1995;3513-3519.
18. Schmitt T.L., Steiner E., Klingler P., Sztankay A., Grubeck-Loebenstein B. The production of an amyloidogenic metabolite of the Alzheimer amyloid β precursor protein (APP) in thyroid cells is stimulated by interleukin 1β, but inhibited by interferon gamma. J. Clin. Endocrinol. Metab. 4:1996;1666-1669.
19. Schmitt T.L., Steiner E., Trieb K., Grubeck-Lobenstein B. Amyloid β protein (25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells. Exp. Cell Res. 234:1997;336-340.
20. Trieb K., Grubeck-Loebenstein B., Eberl T., Margreiter R. T cells from rejected human kidney allografts respond to heat shock protein 72. Transplant. Immunol. 4:1996;43-45.
21. Vandenabeele P., Fiers W. Is amyloidosis during Alzheimer's disease due to an IL-1/IL-6-mediated 'acute phase response' in the brain? Immunol. Today. 12:1993;217-219.
22. Wright S.C., Kumar K., Tam A.W., Shen N., Varma M., Larrick J.W. Apoptosis and DNA fragmentation precede TNF-induced cytolysis in U937 cells. J. Cell. Biochem. 48:1992;344-355.