Cardiomyocyte mitochondrial KATP channels participate in the antiarrhythmic and antiinfarct effects of KATP activators during ischemia and reperfusion in an intact anesthetized rabbit model

Polish Journal of Pharmacology

Volumn 55, Issue 5, 2003, Pages 771-786

  Das, Biswadeep ^a   Sarkar, Chayna ^b  

^a SIKKIM MANIPAL INSTITUTE OF MEDICAL SCIENCES   (India)

^b MANIPAL UNIVERSITY   (India)

Author keywords

Anesthetized rabbit; Coronary occlusion; Free radicals; HMR 1883; Mitochondrial KATP channel; Myocardial ischemia; Nicorandil; Pinacidil; Reperfusion arrhythmia; Sarcolemmal KATP channel

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE; CLAMIKALANT; FREE RADICAL; GLUTATHIONE; MALONALDEHYDE; NICORANDIL; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; 5-HYDROXYDECANOIC ACID; DECANOIC ACID DERIVATIVE; DRUG DERIVATIVE; HYDROXYACID; INWARDLY RECTIFYING POTASSIUM CHANNEL; MEMBRANE PROTEIN; MITOCHONDRIAL K(ATP) CHANNEL; SULFONAMIDE; THIOUREA;

ANESTHESIOLOGICAL TECHNIQUES; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIARRHYTHMIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY LIGATION; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DISEASE SEVERITY; DRUG ACTIVITY; HEART ARRHYTHMIA; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART MUSCLE REPERFUSION; HEART PROTECTION; INCIDENCE; MALE; MITOCHONDRION; NONHUMAN; RABBIT; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE; SURVIVAL; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; CHEMISTRY; COMPARATIVE STUDY; CORONARY BLOOD VESSEL; DISEASE MODEL; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; HEART MITOCHONDRION; INJURY; INTRAVENOUS DRUG ADMINISTRATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; PREMEDICATION;

ANIMALS; ARRHYTHMIA; BLOOD PRESSURE; CORONARY VESSELS; DECANOIC ACIDS; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; GLUTATHIONE; HYDROXY ACIDS; INJECTIONS, INTRAVENOUS; MALE; MALONDIALDEHYDE; MEMBRANE PROTEINS; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NICORANDIL; OXIDATIVE STRESS; PINACIDIL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PREMEDICATION; RABBITS; SULFONAMIDES; SUPEROXIDE DISMUTASE; THIOUREA;

EID: 0346957389     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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