Molecular basis, pharmacology and physiological role of cardiac K(ATP) channels

Cellular Physiology and Biochemistry

Volumn 9, Issue 4-5, 1999, Pages 227-241

  Gögelein, Heinz ^a   Hartung, Jens ^a   Englert, Heinrich C ^a  

^a SANOFI   (France)

Author keywords

ATP dependent potassium channel; Heart; HMR 1883

Indexed keywords

1 [[5 [2 (5 CHLORO 2 ANISAMIDO)ETHYL] 2 METHOXYPHENYL]SULFONYL] 3 METHYLTHIOUREA; CARBUTAMIDE; CLAMIKALANT; CROMAKALIM; DIAZOXIDE; GLIBENCLAMIDE; GLIMEPIRIDE; POTASSIUM CHANNEL; RILMAKALIM; SULFONYLUREA DERIVATIVE; SULFONYLUREA RECEPTOR; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORONARY BLOOD VESSEL; DISEASE MODEL; DOG; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FIBRILLATION; NONHUMAN; PRIORITY JOURNAL; SARCOLEMMA; SMOOTH MUSCLE; SUDDEN DEATH;

ANIMALIA; CANIS FAMILIARIS;

EID: 0033165613     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000016319     Document Type: Article

References (56)

1. Ashcroft FM: Adenosine 5′-triphosphate-sensitive potassium channels. Ann Rev Neurosci 1988;11:97-118.
2. Nichols CG, Lederer WJ: Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. Am J Physiol 1991;261: H1675-H1686.
3. + channels in cardiac muscle. Nature 1983; 305:147-148.
4. Isenberg G, Vereecke J, Heyden Gvd, Carmeliet E: The shortening of the action potential by DNP in guinea pig ventricular myocytes is mediated by an increase of a time-independent K conductance. Pflügers Arch 1983;397:251-259.
5. Wilde AAM, Janse MJ: Electrophysiological effects of ATP sensitive potassium channel modulation: implications for arrhythmogenesis. Cardiovasc Res 1994;28:16-24.
6. Billman GE: Role of ATP sensitive potassium channel in extracellular potassium accumulation and cardiac arrhythmias during myocardial ischaemia. Cardiovasc Res 1994;28: 762-769.
7. + loss and arrhythmias in rat hearts. Circ Res 1990;66:478-485.
8. Wolleben CD, Sanguinetti MC, Siegl PKS: Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts. J Mol Cell Cardiol 1989;21:783-788.
9. Tosaki A: Potassium channel openers and blockers: Do they possess proarrhythmic or antiarrhythmic activity in ischemic and reperfused rat hearts. J Pharmacol Exp Ther 1993;267:1355-1362.
10. ATP channels. Annu Rev Physiol 1998; 60:667-687.
11. ATP channels. Physiol Rev 1998;78:227-245.
12. + channels. Trends Neurosci 1998;21:288-294.
13. ATP channel subunits. Neuron 1997;18: 827-838.
14. + channel. FEBS Lett 1997;409:232-236.
15. ATP channel complex. J Gen Physiol 1998;110: 655-664.
16. Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JP IV, Boyd AE, Gonzalez G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA: Cloning of the β cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science 1995;268: 423-426.
17. KATP : An inward rectifier subunit plus the sulfonylurea receptor. Science 1995;270: 1166-1170.
18. + channels. Neuron 1996;16:1017.
19. ATP channels. Diabetes 1998;47:1412-1418.
20. + channel expressed in a mammalian cell line, HEK293T cells. Pflügers Arch 1998; 435:595-603.
21. + channel. J Biol Chem 1996;271:24321-24324.
22. Edwards G, Weston AH: The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol 1993;33:597-637.
23. Faivre JF, Findlay I: Effects of tolbutamide, glibenclamide and diazoxide upon action potentials recorded from rat ventricular muscle. Biochim Biophys Acta 1989;984:1-5.
24. ATP channels and basal coronary vascular tone. Cardiovasc Res 1994;28:811-817.
25. + channels: Possible mechanism of cardioprotection. Cire Res 1997;81: 1072-1082.
26. ATP channel by glyguride and 5-hydroxydecanoate. J Biol Chem 1998;273:13578-13582.
27. Liu Y, Sato T, O'Rourke B, Marban E: Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection? Circulation 1998;97:2463-2469.
28. Franke H, Fuchs J: Ein neues anti-diabetisches Prinzip. Ergebnisse klinischer Untersuchungen. Dtsch Med Wochenschr 1955;80:1449-1452.
29. Lomuscio A, Vergani D, Marano L, Castagnone M, Fiorentini C: Effects of glibenclamide on ventricular fibrillation in non-insulin-dependent diabetics with acute myocardial infarction. Coronary Artery Dis 1994; 5:767-771.
30. Linz W, Klaus E, Albus U, Becker R. Mania D, Englert HC, Schölkens BA: Cardiovascular effects of the novel potassium channel opener (3S, 4R)-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-phenyl-sulfonylchromane hemihydrate. Br J Pharmacol 1992;121:1024-1030.
31. Gögelein H, Hartung J, Englert HC, Schölkens BA: HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. I. Effects on cardiomyocytes, coronary flow and pancreatic β-cells. J Pharmacol Exp Ther 1998;286: 1453-1464.
32. + channels during metabolic stress in cardiac muscle. J Pharmacol Exp Ther 1993;266:456-467.
33. Krause E, Englert H, Gögelein H: Adenosine triphosphate-dependent K currents activated by metabolic inhibition in rat ventricular myocytes differ from those elicited by the channel opener rilmakalim. Pflügers Arch 1995;429:625-635.
34. 2+ in anoxic rat ventricular myocytes. Effects of glibenclamide. Pflügers Arch 1996;432: 75-80.
35. + loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle. Circ Res 1991;69:623-637.
36. + channel blockers on the action potential shortening in hypoxic and ischaemic myocardium. Br J Pharmacol 1991;103:1019-1026.
37. Barren TD, Walker MJA: Glibenclamide does not prevent action potential shortening induced by ischemia in anesthetized rabbit but reduces ischemia-induced arrhythmias. J Mol Cell Cardiol 1998;30: 999-1008.
38. ATP channels limits energy depletion in the guinea pig heart. Am J Physiol 1995;269:H734-H742.
39. Tweedie D, Henderson C, Kane K: Glibenclamide, but not class III drugs, prevents ischaemic shortening of the refractory period in guinea-pig hearts. Eur J Pharmacol 1993;240:251-257.
40. ATP channels obtained by coexprcssion of human SUR1 and Kir6.2 in mammalian cells. Arch Pharmacol 1998;357:R77.
41. Daut J, Maier-Rudolph W, Von Beckenrath N, Mehrke G, Günther K, Goedel-Meinen L: Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science 1990;247:1341-1344.
42. Dellsperger KC: Potassium channels and the coronary circulation. Clin Exp Pharmacol Physiol 1996; 23:1096-1101.
43. ATP channel blocker HMR 1883 attenuates the effects of ischaemia on MAP duration and improves survival during LAD occlusion in the anaesthetized pig. Br J Pharmacol 1998;124:23P.
44. Schwartz PJ, Billman GE, Stone HE: Autonomic mechanisms in ventricular fibrillation induced by myocardial ischemia during exercise in dogs with healed myocardial infarction: An experimental preparation for sudden cardiac death. Lab Invest 1984;69:790-800.
45. Billman GE, Englert HC, Schölkens BA: HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. II. Effects on susceptibility to ventricular fibrillation induced by myocardial ischemia in conscious dogs. J Pharmacol Exp Ther 1998;286:1465-1473.
46. + channel blockade in the prevention of ventricular fibrillation in dogs with acute ischemia and enhanced sympathetic activity. J Cardiovasc Pharmacol 1995;26:847-854.
47. Vanoli E, Hull SSJ, Jacjman WM, Bussey JD, Foreman RD, Schwartz PJ: Combined blockade of IKr and IKs enhances the arrhythmogenic effect of sympathetic stimulation. Circulation 1996;94:10.
48. Shattock MJ: Channel 'selectivity' and evolution. Has evolutionary pressure and natural selection provided the ATP sensitive potassium channel in the myocardium as an endogenous protection against ischaemic heart disease? Cardiovasc Res 1992;26:1153-1154.
49. ATP channel-deficient mice. Proc Natl Acad Sci USA 1998;95:10402-10406.
50. + channels in cardiac muscle from cold-acclimated goldfish: characterization and altered response to ATP. Comp Biochem Physiol 1998;119A:395-401.
51. 1 -receptors. Circulation 1992;86:1310-1316.
52. Gross GJ, Auchampach JA: Blockade of ATP-sensitive potassium channels prevent myocardial preconditioning in dogs. Circ Res 1992; 70:223-233.
53. Schulz R, Rose J, Heusch G: Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine. Am J Physiol 1994;267:H1341-H1352.
54. ATP channels. Am J Physiol 1995;268: H2294-H2301.
55. ATP channel blocker HMR 1883 in rabbit. Br J Pharmacol 1998;124: 26P.
56. Janse MJ, Wit AL: Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol Rev 1989;69:1049-1169.