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Volumn 25, Issue 3-4, 2003, Pages 365-374

Amino acid and protein oxidation in cardiovascular disease

Author keywords

Atherosclerosis; Chlorination; Free Radical; Inflammation; Lipid peroxidation; Myeloperoxidase; Nitration

Indexed keywords

3 NITROTYROSINE; AMINO ACID; ANTIOXIDANT; FREE RADICAL; MOLECULAR MARKER; MYELOPEROXIDASE; PROTEIN; STATINE;

EID: 0346731060     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-003-0023-y     Document Type: Review
Times cited : (49)

References (103)
  • 1
    • 0000157025 scopus 로고
    • Structure and function of oxidation-reduction enzymes
    • Akeson A, Ehrenberg A (eds). Pergamon Press, Inc. Tarrytown, NY
    • Agner K (1972) Structure and function of oxidation-reduction enzymes. In: Akeson A, Ehrenberg A (eds) Structure and function of oxidation-reduction enzymes. Pergamon Press, Inc. Tarrytown, NY, pp 329-335
    • (1972) Structure and Function of Oxidation-reduction Enzymes , pp. 329-335
    • Agner, K.1
  • 2
    • 0003698541 scopus 로고
    • Biological reactivity of hypochlorous acid: Implications for microbicidal mechanisms of leukocyte myeloperoxidase
    • Albrich JM, McCarthy CA, Hurst JK (1981) Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase. Proc Natl Acad Sci USA 78: 210-214
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 210-214
    • Albrich, J.M.1    McCarthy, C.A.2    Hurst, J.K.3
  • 3
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames BN, Shigenaga MK, Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90: 7915-7922
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 4
    • 0030854261 scopus 로고    scopus 로고
    • Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein: A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation
    • Anderson MM, Hazen SL, Hsu FF, Heinecke JW (1997) Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein: A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation. J Clin Invest 99: 424-432
    • (1997) J Clin Invest , vol.99 , pp. 424-432
    • Anderson, M.M.1    Hazen, S.L.2    Hsu, F.F.3    Heinecke, J.W.4
  • 5
    • 0037416219 scopus 로고    scopus 로고
    • Myeloperoxidase and plasminogen activator inhibitor-1 play a central role in ventricular remodeling after myocardial infarction
    • Askari, AT, Brennan ML, Zhou X, Thomas JD, Topol EJ, Hazen SL, Penn MS (2003) Myeloperoxidase and plasminogen activator inhibitor-1 play a central role in ventricular remodeling after myocardial infarction. J Exp Med 197 (5): 615-624
    • (2003) J Exp Med , vol.197 , Issue.5 , pp. 615-624
    • Askari, A.T.1    Brennan, M.L.2    Zhou, X.3    Thomas, J.D.4    Topol, E.J.5    Hazen, S.L.6    Penn, M.S.7
  • 6
    • 0017834531 scopus 로고
    • Oxygen-dependent microbial killing by phagocytes
    • Babior BM (1978) Oxygen-dependent microbial killing by phagocytes. N Engl J Med 298: 659-663
    • (1978) N Engl J Med , vol.298 , pp. 659-663
    • Babior, B.M.1
  • 8
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87: 1620-1624
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 13
    • 0037124020 scopus 로고    scopus 로고
    • A tale of two controversies: i) Defining the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase deficient mice; and ii) Defining the nature of peroxidase-generated reactive nitrogen species
    • Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HA, Ischiropoulos H, Hazen SL (2002) A tale of two controversies: i) Defining the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase deficient mice; and ii) Defining the nature of peroxidase-generated reactive nitrogen species. J Biol Chem 277: 17415-17427
    • (2002) J Biol Chem , vol.277 , pp. 17415-17427
    • Brennan, M.L.1    Wu, W.2    Fu, X.3    Shen, Z.4    Song, W.5    Frost, H.6    Narine, L.7    Lenkiewicz, E.8    Borchers, M.T.9    Lusis, A.J.10    Lee, J.J.11    Lee, N.A.12    Abu-Soud, H.A.13    Ischiropoulos, H.14    Hazen, S.L.15
  • 14
    • 0035282844 scopus 로고    scopus 로고
    • Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris
    • Cannon CP, McCabe CH, Wilcox RG, Bentley JH, Braunwald E (2001) Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. Am J Cardiol 87: 636-639
    • (2001) Am J Cardiol , vol.87 , pp. 636-639
    • Cannon, C.P.1    McCabe, C.H.2    Wilcox, R.G.3    Bentley, J.H.4    Braunwald, E.5
  • 15
    • 0030750723 scopus 로고    scopus 로고
    • Xanthine oxidase Inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients
    • Cardillo C, Kilcoyne CM, Cannon RO 3rd, Quyumi AA, Panza JA (1997) Xanthine oxidase Inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients. Hypertension 30: 57-63
    • (1997) Hypertension , vol.30 , pp. 57-63
    • Cardillo, C.1    Kilcoyne, C.M.2    Cannon III, R.O.3    Quyumi, A.A.4    Panza, J.A.5
  • 16
    • 0028885708 scopus 로고
    • Human suction blister interstitial fluid prevents metal ion-dependent oxidation of low density lipoprotein by macrophage and in cell-free systems
    • Dabbagh AJ, Frei B (1995) Human suction blister interstitial fluid prevents metal ion-dependent oxidation of low density lipoprotein by macrophage and in cell-free systems. J Clin Invest 96: 1958-1966
    • (1995) J Clin Invest , vol.96 , pp. 1958-1966
    • Dabbagh, A.J.1    Frei, B.2
  • 17
    • 0032513756 scopus 로고    scopus 로고
    • Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease
    • Danesh J, Collins R, Appleby P, Peto R (1998) Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease. JAMA 279: 1477-1482
    • (1998) JAMA , vol.279 , pp. 1477-1482
    • Danesh, J.1    Collins, R.2    Appleby, P.3    Peto, R.4
  • 18
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidants, is expressed in human atherosclerotic lesions
    • Daugherty A, Dunn JL, Rateri DLm Heinecke JW (1994) Myeloperoxidase, a catalyst for lipoprotein oxidants, is expressed in human atherosclerotic lesions. J Clin Invest 94: 437-444
    • (1994) J Clin Invest , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 19
    • 0033429334 scopus 로고    scopus 로고
    • Stable markers of oxidant damage to proteins and their application in the study of human disease
    • Davies MJ, Fu S, Hongjie W, Dean RT (1999) Stable markers of oxidant damage to proteins and their application in the study of human disease. Free Radic Biol Med 27: 1151-1163
    • (1999) Free Radic Biol Med , vol.27 , pp. 1151-1163
    • Davies, M.J.1    Fu, S.2    Hongjie, W.3    Dean, R.T.4
  • 20
  • 21
    • 0029760021 scopus 로고    scopus 로고
    • Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid: A novel mechanism for nitric oxide-mediated protein modification
    • Eiserich JP, Cross CE, Jones AD, Halliwell B, van der Vleit A (1996) Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid: A novel mechanism for nitric oxide-mediated protein modification. J Biol Chem 271: 19199-19208
    • (1996) J Biol Chem , vol.271 , pp. 19199-19208
    • Eiserich, J.P.1    Cross, C.E.2    Jones, A.D.3    Halliwell, B.4    Van Der Vleit, A.5
  • 22
    • 0032556905 scopus 로고    scopus 로고
    • Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
    • Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B (1998) Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391: 393-397
    • (1998) Nature , vol.391 , pp. 393-397
    • Eiserich, J.P.1    Hristova, M.2    Cross, C.E.3    Jones, A.D.4    Freeman, B.A.5    Halliwell, B.6
  • 24
    • 0020702109 scopus 로고
    • Assessment of chlorination by human neutrophils
    • Foote CS, Goyne TE, Lehrer RI (1983) Assessment of chlorination by human neutrophils. Nature 301: 715-716
    • (1983) Nature , vol.301 , pp. 715-716
    • Foote, C.S.1    Goyne, T.E.2    Lehrer, R.I.3
  • 26
    • 0027267487 scopus 로고
    • Oxidative tyrosylation of high density lipoproteins by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cells
    • Francis GA, Mendez AJ, Bierman EL, Heinecke JW (1993) Oxidative tyrosylation of high density lipoproteins by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cells. Proc Natl Acad Sci USA 90: 6631-6634
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6631-6634
    • Francis, G.A.1    Mendez, A.J.2    Bierman, E.L.3    Heinecke, J.W.4
  • 27
    • 0034141819 scopus 로고    scopus 로고
    • Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts
    • Frost MT, Halliwell B, Moore KP (2000) Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts. Biochem J 345: 453-458
    • (2000) Biochem J , vol.345 , pp. 453-458
    • Frost, M.T.1    Halliwell, B.2    Moore, K.P.3
  • 28
    • 0032143406 scopus 로고    scopus 로고
    • Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
    • Fu S, Davies MJ, Stocker R, Dean RT (1998) Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque. Biochem 333: 519-525
    • (1998) Biochem , vol.333 , pp. 519-525
    • Fu, S.1    Davies, M.J.2    Stocker, R.3    Dean, R.T.4
  • 29
    • 0035798684 scopus 로고    scopus 로고
    • Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7): A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase
    • Fu X, Kassini SY, Parks WC, Heinecke JW (2001) Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7): A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem 276: 41279-41287
    • (2001) J Biol Chem , vol.276 , pp. 41279-41287
    • Fu, X.1    Kassini, S.Y.2    Parks, W.C.3    Heinecke, J.W.4
  • 30
    • 0027162279 scopus 로고
    • Peroxynitrite modification of low-density lipoproteins leads to recognition by the macrophage scavenger receptor
    • Graham A, Hogg N, Kalyanaraman B, O'Leary V, Darley-Usmar V, Moncada S (1993) Peroxynitrite modification of low-density lipoproteins leads to recognition by the macrophage scavenger receptor. FEBS Lett 330: 181-185
    • (1993) FEBS Lett , vol.330 , pp. 181-185
    • Graham, A.1    Hogg, N.2    Kalyanaraman, B.3    O'Leary, V.4    Darley-Usmar, V.5    Moncada, S.6
  • 31
    • 0017240322 scopus 로고
    • Studies on the chlorinating activity of myeloperoxidase
    • Harrison JE, Schultz J (1976) Studies on the chlorinating activity of myeloperoxidase. J Biol Chem 251: 1371-1374
    • (1976) J Biol Chem , vol.251 , pp. 1371-1374
    • Harrison, J.E.1    Schultz, J.2
  • 32
    • 0002019504 scopus 로고    scopus 로고
    • Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols
    • Hazen SL, Hsu FF, Duffin K, Heinecke JW (1996a) Molecular chlorine generated by the myeloperoxidase-hydrogen peroxide-chloride system of phagocytes converts low density lipoprotein cholesterol into a family of chlorinated sterols. J Biol Chem 271: 23080-23088
    • (1996) J Biol Chem , vol.271 , pp. 23080-23088
    • Hazen, S.L.1    Hsu, F.F.2    Duffin, K.3    Heinecke, J.W.4
  • 34
    • 0030053876 scopus 로고    scopus 로고
    • p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes: A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase
    • Hazen SL, Hsu FF, Heinecke JW (1996c) p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes: A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase. J Biol Chem 271: 1861-1867
    • (1996) J Biol Chem , vol.271 , pp. 1861-1867
    • Hazen, S.L.1    Hsu, F.F.2    Heinecke, J.W.3
  • 35
    • 0030979720 scopus 로고    scopus 로고
    • 3-Chlorotyrosine, a specific marker for myeloperoxidase-catalyzed halogenation, is present in human atherosclerotic aorta
    • Hazen SL, Heinecke JW (1997a) 3-Chlorotyrosine, a specific marker for myeloperoxidase-catalyzed halogenation, is present in human atherosclerotic aorta. J Clin Invest 99: 2075-2081
    • (1997) J Clin Invest , vol.99 , pp. 2075-2081
    • Hazen, S.L.1    Heinecke, J.W.2
  • 36
    • 0030872969 scopus 로고    scopus 로고
    • 2-Cl system of phagocytes, covalently modifies Nε-lysine residues of proteins
    • 2-Cl system of phagocytes, covalently modifies Nε-lysine residues of proteins. J Biol Chem 272: 169990-16998
    • (1997) J Biol Chem , vol.272 , pp. 169990-216998
    • Hazen, S.L.1    Gaut, J.P.2    Hsu, F.F.3
  • 37
    • 0032570808 scopus 로고    scopus 로고
    • - -system to oxidize α-amino acids to a family of reactive aldehydes: Mechanistic studies identifying labile intermediates along the reaction pathway
    • - -system to oxidize α-amino acids to a family of reactive aldehydes: Mechanistic studies identifying labile intermediates along the reaction pathway. J Biol Chem 273: 4997-5005
    • (1998) J Biol Chem , vol.273 , pp. 4997-5005
    • Hazen, S.L.1    D'Avignon, A.2    Anderson, M.M.3    Hsu, F.F.4    Heinecke, J.W.5
  • 38
    • 0032510811 scopus 로고    scopus 로고
    • Human neutrophils employ myeloperoxidase to convert α-amino acids to a battery of reactive aldehydes: A pathway for aldehyde formation at sites of inflammation
    • Hazen SL, Hsu FF, d'Avignon A, Heinecke JW (1998b) Human neutrophils employ myeloperoxidase to convert α-amino acids to a battery of reactive aldehydes: A pathway for aldehyde formation at sites of inflammation. Biochemistry 37: 6864-6873
    • (1998) Biochemistry , vol.37 , pp. 6864-6873
    • Hazen, S.L.1    Hsu, F.F.2    D'Avignon, A.3    Heinecke, J.W.4
  • 40
    • 0032937594 scopus 로고    scopus 로고
    • Synthesis, isolation and characterization of the adduct formed in the reaction of p-hydroxyphenylacetaldehyde with the amino head group of phosphatidyl ethanolamine and phosphatidylserine
    • Hazen SL, Heller J, Hsu FF, d'Avignon A, Heinecke JW (1999b) Synthesis, isolation and characterization of the adduct formed in the reaction of p-hydroxyphenylacetaldehyde with the amino head group of phosphatidyl ethanolamine and phosphatidylserine. Chem Res Toxicol 12: 19-27
    • (1999) Chem Res Toxicol , vol.12 , pp. 19-27
    • Hazen, S.L.1    Heller, J.2    Hsu, F.F.3    D'Avignon, A.4    Heinecke, J.W.5
  • 41
    • 0034672422 scopus 로고    scopus 로고
    • Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
    • Hazen SL, Gaut JP, Crowley JR, Hsu FF, Heinecke JW (2000) Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions. Biochem J 352: 693-699
    • (2000) Biochem J , vol.352 , pp. 693-699
    • Hazen, S.L.1    Gaut, J.P.2    Crowley, J.R.3    Hsu, F.F.4    Heinecke, J.W.5
  • 42
    • 0027292790 scopus 로고
    • Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking proteins
    • Heinecke JW, Li W, Francis GA, Goldstein JA (1993) Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking proteins. J Clin Invest 91: 2866-2872
    • (1993) J Clin Invest , vol.91 , pp. 2866-2872
    • Heinecke, J.W.1    Li, W.2    Francis, G.A.3    Goldstein, J.A.4
  • 43
    • 0035573705 scopus 로고    scopus 로고
    • Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis
    • Heinecke JW (2001) Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis. Arterioscler Thromb Vasc Biol 21: 1261-1264
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1261-1264
    • Heinecke, J.W.1
  • 44
    • 0036679823 scopus 로고    scopus 로고
    • Tyrosyl radical production by myelperoxidase: A phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins
    • Heinecke JW (2002) Tyrosyl radical production by myelperoxidase: A phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins. Toxicology 177: 11-22
    • (2002) Toxicology , vol.177 , pp. 11-22
    • Heinecke, J.W.1
  • 45
    • 0034615999 scopus 로고    scopus 로고
    • Hydroxyphenylactaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima
    • Heller JI, Crowley JR, Hazen SL, Salvay DM, Wagner P, Pennathur S, Heinecke JW (2000) p-Hydroxyphenylactaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima. J Biol Chem 275: 9957-9962
    • (2000) J Biol Chem , vol.275 , pp. 9957-9962
    • Heller, J.I.1    Crowley, J.R.2    Hazen, S.L.3    Salvay, D.M.4    Wagner, P.5    Pennathur, S.6    Heinecke, J.W.7
  • 47
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases. The role of oxidant stress
    • Hua C, Harrison DG (2000) Endothelial dysfunction in cardiovascular diseases. The role of oxidant stress. Circ Res 87: 840-844
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Hua, C.1    Harrison, D.G.2
  • 48
    • 0027180882 scopus 로고
    • Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation
    • Huggins TG, Wells-Knecht MC, Detorie NA, Baynes JW, Thorpe SR (1993) Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation. J Biol Chem 268: 12341-12347
    • (1993) J Biol Chem , vol.268 , pp. 12341-12347
    • Huggins, T.G.1    Wells-Knecht, M.C.2    Detorie, N.A.3    Baynes, J.W.4    Thorpe, S.R.5
  • 49
    • 0031438748 scopus 로고    scopus 로고
    • Relative chlorinating, nitrating, and oxidizing capabilities of neutrophils determined with phagocytosable probes
    • Jiang Q, Hurst JK (1997) Relative chlorinating, nitrating, and oxidizing capabilities of neutrophils determined with phagocytosable probes. J Biol Chem 272: 32767-32772
    • (1997) J Biol Chem , vol.272 , pp. 32767-32772
    • Jiang, Q.1    Hurst, J.K.2
  • 50
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium
    • Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA (1999) Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium. Hypertension 33: 1353-1358
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 51
    • 0034121607 scopus 로고    scopus 로고
    • Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
    • Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC (2000) Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arterioscler Thromb Vasc Biol 20: 1529-1535
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1529-1535
    • Kirk, E.A.1    Dinauer, M.C.2    Rosen, H.3    Chait, A.4    Heinecke, J.W.5    LeBoeuf, R.C.6
  • 52
    • 0018838058 scopus 로고
    • Oxygen metabolism and the toxic properties of phagocytes
    • Klebanoff SJ (1980) Oxygen metabolism and the toxic properties of phagocytes. Ann Intern Med 93: 480-489
    • (1980) Ann Intern Med , vol.93 , pp. 480-489
    • Klebanoff, S.J.1
  • 54
    • 0035874967 scopus 로고    scopus 로고
    • Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
    • Lee SH, Oe T, Blair IA (2001) Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins. Science 2001 292: 2083-2086
    • (2001) Science 2001 , vol.292 , pp. 2083-2086
    • Lee, S.H.1    Oe, T.2    Blair, I.A.3
  • 56
    • 0031021944 scopus 로고    scopus 로고
    • Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoproteins isolated from human atherosclerotic plaques
    • Leewenburgh C, Rasmussen JE, Hsu FF, Mueller DM, Pennathur S, Heinecke JW (1997b) Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoproteins isolated from human atherosclerotic plaques. J Biol Chem 272: 3520-3526
    • (1997) J Biol Chem , vol.272 , pp. 3520-3526
    • Leewenburgh, C.1    Rasmussen, J.E.2    Hsu, F.F.3    Mueller, D.M.4    Pennathur, S.5    Heinecke, J.W.6
  • 57
    • 0029054734 scopus 로고
    • Molecular basis of the acute coronary syndromes
    • Libby P (1995) Molecular basis of the acute coronary syndromes. Circulation 91: 2844-2850
    • (1995) Circulation , vol.91 , pp. 2844-2850
    • Libby, P.1
  • 58
    • 0035340289 scopus 로고    scopus 로고
    • Eosinophils are a major source of NO-derived oxidants in severe asthma: Characterization of pathways available to eosinophils for generating reactive nitrogen species
    • MacPherson JC, Comhair SA, Erzurum SC, Klein DF, Lipscomb MF, Kavuru MS, Samoszuk M, Hazen SL (2001) Eosinophils are a major source of NO-derived oxidants in severe asthma: Characterization of pathways available to eosinophils for generating reactive nitrogen species. J Immunology 166: 5763-5772
    • (2001) J Immunology , vol.166 , pp. 5763-5772
    • MacPherson, J.C.1    Comhair, S.A.2    Erzurum, S.C.3    Klein, D.F.4    Lipscomb, M.F.5    Kavuru, M.S.6    Samoszuk, M.7    Hazen, S.L.8
  • 61
    • 0035110882 scopus 로고    scopus 로고
    • The proper study of mankind
    • Nauseef WM (2001) The proper study of mankind. J Clin Invest 107: 401-403
    • (2001) J Clin Invest , vol.107 , pp. 401-403
    • Nauseef, W.M.1
  • 62
    • 0026454807 scopus 로고
    • Leukocyte count correlates in middle-aged adults: The atherosclerosis risk in communities (ARIC) study
    • Nieto FJ, Szklo M, Folsom AR, Rock R, Mercuri M (1992) Leukocyte count correlates in middle-aged adults: The atherosclerosis risk in communities (ARIC) study. Am J Epidemiol 136: 525-537
    • (1992) Am J Epidemiol , vol.136 , pp. 525-537
    • Nieto, F.J.1    Szklo, M.2    Folsom, A.R.3    Rock, R.4    Mercuri, M.5
  • 63
    • 0034904840 scopus 로고    scopus 로고
    • A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians
    • Nikpoor B, Turecki G, Fournier C, Theroux P, Rouleau GA (2001) A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians. Amer Heart J 142: 336-339
    • (2001) Amer Heart J , vol.142 , pp. 336-339
    • Nikpoor, B.1    Turecki, G.2    Fournier, C.3    Theroux, P.4    Rouleau, G.A.5
  • 64
    • 0027242030 scopus 로고
    • Hypercholesterolemia increase endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG (1993) Hypercholesterolemia increase endothelial superoxide anion production. J Clin Invest 91: 2546-2551
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 66
    • 0011489860 scopus 로고
    • Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils
    • Peppin GJ, Weiss SJ (1986) Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils. Proc Natl Acad Sci USA 83: 4322-4326
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4322-4326
    • Peppin, G.J.1    Weiss, S.J.2
  • 68
    • 0032701646 scopus 로고    scopus 로고
    • Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
    • Podrez EA, Schmidt D, Hoff HF, Hazen SL (1999) Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J Clin Invest 103: 1547-1560
    • (1999) J Clin Invest , vol.103 , pp. 1547-1560
    • Podrez, E.A.1    Schmidt, D.2    Hoff, H.F.3    Hazen, S.L.4
  • 69
    • 0034659164 scopus 로고    scopus 로고
    • Myeloperoxidase-generated oxidants and atherosclerosis
    • Podrez EA, Abu-Soud HM, Hazen SL (2000a) Myeloperoxidase-generated oxidants and atherosclerosis. Free Rad Biol Med 28: 1717-1725
    • (2000) Free Rad Biol Med , vol.28 , pp. 1717-1725
    • Podrez, E.A.1    Abu-Soud, H.M.2    Hazen, S.L.3
  • 71
    • 0023142981 scopus 로고
    • C-reactive protein immunohistochemical localization in normal and atherosclerotic human aortas
    • Reynolds GD, Vance RP (1987) C-reactive protein immunohistochemical localization in normal and atherosclerotic human aortas. Arch Pathol Lab Med 111: 265-269
    • (1987) Arch Pathol Lab Med , vol.111 , pp. 265-269
    • Reynolds, G.D.1    Vance, R.P.2
  • 72
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
    • Ridker PM, Cushman M, Stampfer MJ Tracy RP, Hennekens CH (1997) Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336: 973-979
    • (1997) N Engl J Med , vol.336 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 73
    • 0035963529 scopus 로고    scopus 로고
    • Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events
    • Air Force/Texas Coronary Atherosclerosis Prevention Study Investigators
    • Ridker PM, Rifai N, Clearfield M, Downs JR, Weis SE, Miles JS, Gotto AM (2001) Air Force/Texas Coronary Atherosclerosis Prevention Study Investigators. Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. N Engl J Med 344: 1959-1965
    • (2001) N Engl J Med , vol.344 , pp. 1959-1965
    • Ridker, P.M.1    Rifai, N.2    Clearfield, M.3    Downs, J.R.4    Weis, S.E.5    Miles, J.S.6    Gotto, A.M.7
  • 74
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-809
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 75
    • 0034646624 scopus 로고    scopus 로고
    • Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate
    • Rubbo H, Radi R, Anselmi D, et al. (2000) Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. J Biol Chem 275: 10812-10818
    • (2000) J Biol Chem , vol.275 , pp. 10812-10818
    • Rubbo, H.1    Radi, R.2    Anselmi, D.3
  • 76
    • 0031837825 scopus 로고    scopus 로고
    • The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCl) is suppressed by anti-rheumatic drug
    • Shabani F, McNeil J, Tippett L (1998) The oxidative inactivation of tissue inhibitor of metalloproteinase-1 (TIMP-1) by hypochlorous acid (HOCl) is suppressed by anti-rheumatic drug. Free Radic Res 28: 115-123
    • (1998) Free Radic Res , vol.28 , pp. 115-123
    • Shabani, F.1    McNeil, J.2    Tippett, L.3
  • 80
    • 0025096722 scopus 로고
    • Multiple modes of activation of latent human fibroblast collagenase: Evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation
    • Springman EB, Angleton EL, Birkedal-Hansen H, Van Wart HE (1990) Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci USA 87: 364-368
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 364-368
    • Springman, E.B.1    Angleton, E.L.2    Birkedal-Hansen, H.3    Van Wart, H.E.4
  • 81
    • 0026795635 scopus 로고
    • Protein oxidation and aging
    • Stadtman ER (1992) Protein oxidation and aging. Science 257: 1220-1224
    • (1992) Science , vol.257 , pp. 1220-1224
    • Stadtman, E.R.1
  • 82
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge heart antioxidant study (CHAOS)
    • Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ (1996) Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge heart antioxidant study (CHAOS). Lancet 347: 781-786
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 83
    • 0035108136 scopus 로고    scopus 로고
    • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes
    • Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P (2001) Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 158: 879-891
    • (2001) Am J Pathol , vol.158 , pp. 879-891
    • Sugiyama, S.1    Okada, Y.2    Sukhova, G.K.3    Virmani, R.4    Heinecke, J.W.5    Libby, P.6
  • 84
    • 0026731716 scopus 로고
    • The influence of medium components on Cu-dependent oxidation of low density lipoproteins and its sensitivity to superoxide dismutase
    • Thomas CE (1992) The influence of medium components on Cu-dependent oxidation of low density lipoproteins and its sensitivity to superoxide dismutase. Biochim Biophys Acta 1128: 50-57
    • (1992) Biochim Biophys Acta , vol.1128 , pp. 50-57
    • Thomas, C.E.1
  • 85
    • 0020361724 scopus 로고
    • Myeloperoxidase-catalyzed incorporation of amines into proteins: Role of hypochlorous acid and dichloramines
    • Thomas EL, Jefferson MM, Grisham MB (1982) Myeloperoxidase-catalyzed incorporation of amines into proteins: Role of hypochlorous acid and dichloramines. Biochemistry 21: 6299-6308
    • (1982) Biochemistry , vol.21 , pp. 6299-6308
    • Thomas, E.L.1    Jefferson, M.M.2    Grisham, M.B.3
  • 86
    • 0034659172 scopus 로고    scopus 로고
    • Molecular action of vitamin E in lipoprotein oxidation: Implication for atherosclerosis
    • Thomas SR, Stocker R (2000) Molecular action of vitamin E in lipoprotein oxidation: Implication for atherosclerosis. Free Radic Biol Med 28: 1795-1805
    • (2000) Free Radic Biol Med , vol.28 , pp. 1795-1805
    • Thomas, S.R.1    Stocker, R.2
  • 88
    • 0036566151 scopus 로고    scopus 로고
    • Oxidized lipid accumulates in the presence of alpha-tocopherol in atherosclerosis
    • Upston JM, Ternetis AC, Morris K, Keaney Jr JF, Stocker R (2002b) Oxidized lipid accumulates in the presence of alpha-tocopherol in atherosclerosis. Biochem J 363: 753-760
    • (2002) Biochem J , vol.363 , pp. 753-760
    • Upston, J.M.1    Ternetis, A.C.2    Morris, K.3    Keaney Jr., J.F.4    Stocker, R.5
  • 89
    • 0030909465 scopus 로고    scopus 로고
    • Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity
    • van der Vleit A, Eiserich JP, Halliwell B, Cross CE (1997) Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity. J Biol Chem 272: 7617-7625
    • (1997) J Biol Chem , vol.272 , pp. 7617-7625
    • Van Der Vleit, A.1    Eiserich, J.P.2    Halliwell, B.3    Cross, C.E.4
  • 90
    • 0021801170 scopus 로고
    • Immunoglobulins and complement components in human aortic atherosclerotic intima
    • Vlaicu R, Rus HG, Niculescu F, Cristea A (1985) Immunoglobulins and complement components in human aortic atherosclerotic intima. Atherosclerosis 55: 35-50
    • (1985) Atherosclerosis , vol.55 , pp. 35-50
    • Vlaicu, R.1    Rus, H.G.2    Niculescu, F.3    Cristea, A.4
  • 91
    • 0032504235 scopus 로고    scopus 로고
    • Enhanced cholesterol efflux by tyrosyl radical-oxidized high density lipoprotein is mediated by apolipoprotein AI-AII heterodimers
    • Wang WQ, Merriam DL, Moses AS, Francis GA (1998) Enhanced cholesterol efflux by tyrosyl radical-oxidized high density lipoprotein is mediated by apolipoprotein AI-AII heterodimers. J Biol Chem 273: 17391-17398
    • (1998) J Biol Chem , vol.273 , pp. 17391-17398
    • Wang, W.Q.1    Merriam, D.L.2    Moses, A.S.3    Francis, G.A.4
  • 92
    • 0000752259 scopus 로고
    • Kinetic studies on the chloramines. I. The rates of formation of monochloramine, N-chlormethylamine and N-chlordimethylamine
    • Weil I, Morris JC (1949) Kinetic studies on the chloramines. I. The rates of formation of monochloramine, N-chlormethylamine and N-chlordimethylamine. J Am Chem Soc 71: 1664-1671
    • (1949) J Am Chem Soc , vol.71 , pp. 1664-1671
    • Weil, I.1    Morris, J.C.2
  • 93
    • 0019988650 scopus 로고
    • Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation
    • Weiss SJ, Klein R, Slivka A, Wei M (1982) Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation. J Clin Invest 70: 598-607
    • (1982) J Clin Invest , vol.70 , pp. 598-607
    • Weiss, S.J.1    Klein, R.2    Slivka, A.3    Wei, M.4
  • 95
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss SJ (1989) Tissue destruction by neutrophils. N Engl J Med 320: 365-376
    • (1989) N Engl J Med , vol.320 , pp. 365-376
    • Weiss, S.J.1
  • 96
    • 0242582879 scopus 로고
    • Chemistry of chlorination
    • White GC (ed). Van Nostrand Reinhold, New York, NY
    • White GC (1972) Chemistry of chlorination. In White GC (ed) Handbook of chlorination. Van Nostrand Reinhold, New York, NY pp 182-227
    • (1972) Handbook of Chlorination , pp. 182-227
    • White, G.C.1
  • 98
    • 0035176943 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherosclerosis: Does it hold for humans?
    • Witztum JL, Steinberg D (2001) The oxidative modification hypothesis of atherosclerosis: does it hold for humans? Trends Cardiovasc Med 11: 93-102
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 93-102
    • Witztum, J.L.1    Steinberg, D.2
  • 99
    • 0033520499 scopus 로고    scopus 로고
    • Eosinophil peroxidase nitrates protein tyrosyl residues. Implication for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders
    • Wu W, Chen Y, Hazen SL (1999a) Eosinophil peroxidase nitrates protein tyrosyl residues. Implication for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders. J Biol Chem 274: 25933-25944
    • (1999) J Biol Chem , vol.274 , pp. 25933-25944
    • Wu, W.1    Chen, Y.2    Hazen, S.L.3
  • 100
    • 0033596905 scopus 로고    scopus 로고
    • 3-Bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: Potential markers for eosinophil-dependent tissue injury in vivo
    • Wu W, d'Avignon A, Chen YH, Hazen SL (1999b) 3-Bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: Potential markers for eosinophil-dependent tissue injury in vivo. Biochemistry 38: 3538-3548
    • (1999) Biochemistry , vol.38 , pp. 3538-3548
    • Wu, W.1    D'Avignon, A.2    Chen, Y.H.3    Hazen, S.L.4
  • 102
    • 0037195783 scopus 로고    scopus 로고
    • Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation
    • Zhang R, Brennan ML, Shen Z, MacPherson JC, Schmitt D, Molenda C, Hazen SL (2002a) Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation. J Biol Chem 277: 46116-46122
    • (2002) J Biol Chem , vol.277 , pp. 46116-46122
    • Zhang, R.1    Brennan, M.L.2    Shen, Z.3    MacPherson, J.C.4    Schmitt, D.5    Molenda, C.6    Hazen, S.L.7
  • 103
    • 0036493406 scopus 로고    scopus 로고
    • The role of myeloperoxidase in the initiation of lipid peroxidation in plasma as studied in neutrophils isolated from myeloperoxidase deficient subjects: Systematic approach to the identification and characterization of multiple diffusible endogenous substrates for myeloperoxidase in plasma
    • Zhang R, Shen Z, Nauseef WM, Hazen SL (2002b) The role of myeloperoxidase in the initiation of lipid peroxidation in plasma as studied in neutrophils isolated from myeloperoxidase deficient subjects: Systematic approach to the identification and characterization of multiple diffusible endogenous substrates for myeloperoxidase in plasma. Blood 99: 1802-1810
    • (2002) Blood , vol.99 , pp. 1802-1810
    • Zhang, R.1    Shen, Z.2    Nauseef, W.M.3    Hazen, S.L.4


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