Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions

Biochemical Journal

Volumn 352, Issue 3, 2000, Pages 693-699

  Hazen, S L ^a   Gaut, J P ^a   Crowley, J R ^a   Hsu, F F ^a   Heinecke, J W ^a  

^a Box 8046   (United States)

Author keywords

Antioxidant; Carbonyl; Hypochlorous acid; Oxidative stress; Oxidized low density lipoprotein

Indexed keywords

4 HYDROXYPHENYLACETIC ACID; ACETALDEHYDE; AMINO ACID DERIVATIVE; ANTIOXIDANT; CARBONYL DERIVATIVE; HEMOPROTEIN; HYPOCHLOROUS ACID; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE; SCHIFF BASE; TYROSINE;

AORTA INTIMA; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; SOLUBILITY; VASCULAR TISSUE;

ACETALDEHYDE; ANTIOXIDANTS; AORTA; ARTERIOSCLEROSIS; CHLORIDES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LIPID METABOLISM; LIPOPROTEINS, LDL; LYSINE; PEROXIDASE; SCHIFF BASES; SOLUBILITY; TUNICA INTIMA; TYROSINE; WATER;

EID: 0034672422     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3520693     Document Type: Article

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