메뉴 건너뛰기




Volumn 39, Issue 1, 2004, Pages 15-25

Antisense Blocking of BRCA1 Enhances Sensitivity to Plumbagin but not Tamoxifen in BG-1 Ovarian Cancer Cells

Author keywords

Apoptosis; BRCA1; Ovarian cancer; Plumbagin; Tamoxifen

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; BRCA1 PROTEIN; DNA FRAGMENT; EMODIN; MESSENGER RNA; PLUMBAGIN; TAMOXIFEN;

EID: 0346727359     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10164     Document Type: Article
Times cited : (43)

References (59)
  • 1
    • 0028843102 scopus 로고
    • Breast and ovarian cancer incidence in BRCA1-mutation carriers
    • Breast Cancer Linkage Consortium
    • Easton DF, Ford D, Bishop DT. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Am J Hum Genet 1995;56:265-271.
    • (1995) Am J Hum Genet , vol.56 , pp. 265-271
    • Easton, D.F.1    Ford, D.2    Bishop, D.T.3
  • 2
    • 0028826709 scopus 로고
    • Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence
    • Ford D, Easton DF, Peto J. Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence. Am J Hum Genet 1995;57:1457-1462.
    • (1995) Am J Hum Genet , vol.57 , pp. 1457-1462
    • Ford, D.1    Easton, D.F.2    Peto, J.3
  • 3
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
    • Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miki, Y.1    Swensen, J.2    Shattuck-Eidens, D.3
  • 4
    • 0029115660 scopus 로고
    • The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues
    • Marquis ST, Rajan JV, Wynshaw-Boris A, et al. The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. Nat Genet 1995;11:17-26.
    • (1995) Nat Genet , vol.11 , pp. 17-26
    • Marquis, S.T.1    Rajan, J.V.2    Wynshaw-Boris, A.3
  • 5
    • 0029925529 scopus 로고    scopus 로고
    • Growth retardation and tumour inhibition by BRCA1
    • Holt JT, Thompson ME, Szabo C, et al. Growth retardation and tumour inhibition by BRCA1. Nat Genet 1996;12:298-302.
    • (1996) Nat Genet , vol.12 , pp. 298-302
    • Holt, J.T.1    Thompson, M.E.2    Szabo, C.3
  • 6
    • 0028828673 scopus 로고
    • Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice
    • Lane TF, Deng C, Elson A, Lyu MS, Kozak CA, Leder P. Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev 1995;9:2712-2722.
    • (1995) Genes Dev , vol.9 , pp. 2712-2722
    • Lane, T.F.1    Deng, C.2    Elson, A.3    Lyu, M.S.4    Kozak, C.A.5    Leder, P.6
  • 7
    • 0034723347 scopus 로고    scopus 로고
    • BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
    • MacLachlan TK, Somasundaram K, Sgagias M, et al. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. J Biol Chem 2000;275:2777-2785.
    • (2000) J Biol Chem , vol.275 , pp. 2777-2785
    • MacLachlan, T.K.1    Somasundaram, K.2    Sgagias, M.3
  • 9
    • 0033612303 scopus 로고    scopus 로고
    • Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
    • Harkin DP, Bean JM, Miklos D, et al. Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. Cell 1999;97:575-586.
    • (1999) Cell , vol.97 , pp. 575-586
    • Harkin, D.P.1    Bean, J.M.2    Miklos, D.3
  • 10
    • 0034721885 scopus 로고    scopus 로고
    • BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines
    • Thangaraju M, Kaufmann SH, Couch FJ. BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines. J Biol Chem 2000;275:33487-33496.
    • (2000) J Biol Chem , vol.275 , pp. 33487-33496
    • Thangaraju, M.1    Kaufmann, S.H.2    Couch, F.J.3
  • 11
    • 0029312514 scopus 로고
    • Tumor suppressor genes and their alterations in breast cancer
    • Lee EY. Tumor suppressor genes and their alterations in breast cancer. Semin Cancer Biol 1995;6:119-125.
    • (1995) Semin Cancer Biol , vol.6 , pp. 119-125
    • Lee, E.Y.1
  • 12
    • 0034469046 scopus 로고    scopus 로고
    • Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line
    • Annab LA, Hawkins RE, Solomon G, Barrett JC, Afshari CA. Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line. Breast Cancer Res 2000;2:139-148.
    • (2000) Breast Cancer Res , vol.2 , pp. 139-148
    • Annab, L.A.1    Hawkins, R.E.2    Solomon, G.3    Barrett, J.C.4    Afshari, C.A.5
  • 13
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr BJ, Jordan VC. The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 1984;25:127-205.
    • (1984) Pharmacol Ther , vol.25 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 14
    • 0038287605 scopus 로고    scopus 로고
    • Simple ovarian cysts in postmenopausal patients with breast carcinoma treated with tamoxifen: Long-term follow-up
    • Cohen I, Potlog-Nahari C, Shapira J, Yigael D, Tepper R. Simple ovarian cysts in postmenopausal patients with breast carcinoma treated with tamoxifen: Long-term follow-up. Radiology 2003;227:844-848.
    • (2003) Radiology , vol.227 , pp. 844-848
    • Cohen, I.1    Potlog-Nahari, C.2    Shapira, J.3    Yigael, D.4    Tepper, R.5
  • 15
    • 0026595816 scopus 로고
    • Evaluation of the antiviral activity of anthraquinones, anthrones, and anthraquinone derivatives against human cytomegalovirus
    • Barnard DL, Huffman JH, Morris JL, Wood SG, Hughes BG, Sidwell RW. Evaluation of the antiviral activity of anthraquinones, anthrones, and anthraquinone derivatives against human cytomegalovirus. Antiviral Res 1992;17:63-77.
    • (1992) Antiviral Res , vol.17 , pp. 63-77
    • Barnard, D.L.1    Huffman, J.H.2    Morris, J.L.3    Wood, S.G.4    Hughes, B.G.5    Sidwell, R.W.6
  • 16
    • 0034846756 scopus 로고    scopus 로고
    • Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma
    • Lee HZ. Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma. Br J Pharmacol 2001;134:11-20.
    • (2001) Br J Pharmacol , vol.134 , pp. 11-20
    • Lee, H.Z.1
  • 17
    • 0027372487 scopus 로고
    • Antioxidant and radical scavenging effects of anthraquinones and anthrones
    • Malterud KE, Farbrot TL, Huse AE, Sund RB. Antioxidant and radical scavenging effects of anthraquinones and anthrones. Pharmacology 1993;47(Suppl 1):77-85.
    • (1993) Pharmacology , vol.47 , Issue.SUPPL. 1 , pp. 77-85
    • Malterud, K.E.1    Farbrot, T.L.2    Huse, A.E.3    Sund, R.B.4
  • 18
    • 0030596126 scopus 로고    scopus 로고
    • Genotoxicity of the laxative drug components emodin, aloe-emodin, and danthron in mammalian cells: Topoisomerase II mediated?
    • Muller SO, Eckert I, Lutz WK, Stopper H. Genotoxicity of the laxative drug components emodin, aloe-emodin, and danthron in mammalian cells: Topoisomerase II mediated? Mutat Res 1996;371:165-173.
    • (1996) Mutat Res , vol.371 , pp. 165-173
    • Muller, S.O.1    Eckert, I.2    Lutz, W.K.3    Stopper, H.4
  • 20
    • 0030659848 scopus 로고    scopus 로고
    • A tumor cell growth inhibitor from Polygonum hypoleucum Ohwi
    • Kuo YC, Sun CM, Ou JC, Tsai WJ. A tumor cell growth inhibitor from Polygonum hypoleucum Ohwi. Life Sci 1997;61:2335-2344.
    • (1997) Life Sci , vol.61 , pp. 2335-2344
    • Kuo, Y.C.1    Sun, C.M.2    Ou, J.C.3    Tsai, W.J.4
  • 21
    • 0029118536 scopus 로고
    • Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin
    • Zhang L, Chang CJ, Bacus SS, Hung MC. Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin. Cancer Res 1995;55:3890-3896.
    • (1995) Cancer Res , vol.55 , pp. 3890-3896
    • Zhang, L.1    Chang, C.J.2    Bacus, S.S.3    Hung, M.C.4
  • 22
    • 0042206721 scopus 로고    scopus 로고
    • Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9
    • Srinivas G, Anto RJ, Srinivas P, Vidhyalakshmi S, Senan VP, Karunagaran D. Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9. Eur J Pharmacol 2003;473:117-125.
    • (2003) Eur J Pharmacol , vol.473 , pp. 117-125
    • Srinivas, G.1    Anto, R.J.2    Srinivas, P.3    Vidhyalakshmi, S.4    Senan, V.P.5    Karunagaran, D.6
  • 23
    • 0025837589 scopus 로고
    • Cardiotonic action of plumbagin on guinea-pig papillary muscle
    • Itoigawa M, Takeya K, Furukawa H. Cardiotonic action of plumbagin on guinea-pig papillary muscle. Planta Med 1991;57:317-319.
    • (1991) Planta Med , vol.57 , pp. 317-319
    • Itoigawa, M.1    Takeya, K.2    Furukawa, H.3
  • 25
    • 0031792702 scopus 로고    scopus 로고
    • Synergistic effects of some pairs of antioxidants and related agents on mouse leukaemia L5178Y cell growth in-vitro
    • Suzuki T, Ezure T, Ishida M. Synergistic effects of some pairs of antioxidants and related agents on mouse leukaemia L5178Y cell growth in-vitro. J Pharm Pharmacol 1998;50:1173-1177.
    • (1998) J Pharm Pharmacol , vol.50 , pp. 1173-1177
    • Suzuki, T.1    Ezure, T.2    Ishida, M.3
  • 26
    • 0026748993 scopus 로고
    • Exogenous quinones directly inhibit the respiratory NADH dehydrogenase in Escherichia coli
    • Imlay J, Fridovich I. Exogenous quinones directly inhibit the respiratory NADH dehydrogenase in Escherichia coli. Arch Biochem Biophys 1992;296:337-346.
    • (1992) Arch Biochem Biophys , vol.296 , pp. 337-346
    • Imlay, J.1    Fridovich, I.2
  • 27
    • 0037194607 scopus 로고    scopus 로고
    • Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: Involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1
    • Jaiswal AS, Bloom LB, Narayan S. Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: Involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1. Oncogene 2002;21:5912-5922.
    • (2002) Oncogene , vol.21 , pp. 5912-5922
    • Jaiswal, A.S.1    Bloom, L.B.2    Narayan, S.3
  • 28
    • 0032473879 scopus 로고    scopus 로고
    • BRCA1 physically associates with p53 and stimulates its transcriptional activity
    • Zhang H, Somasundaram K, Peng Y, et al. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene 1998;16:1713-1721.
    • (1998) Oncogene , vol.16 , pp. 1713-1721
    • Zhang, H.1    Somasundaram, K.2    Peng, Y.3
  • 29
    • 0033591295 scopus 로고    scopus 로고
    • BRCA1 inhibition of estrogen receptor signaling in transfected cells
    • Fan S, Wang J, Yuan R, et al. BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 1999;284:1354-1356.
    • (1999) Science , vol.284 , pp. 1354-1356
    • Fan, S.1    Wang, J.2    Yuan, R.3
  • 30
    • 0032542216 scopus 로고    scopus 로고
    • A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability
    • Shen SX, Weaver Z, Xu X, et al. A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. Oncogene 1998;17:3115-3124.
    • (1998) Oncogene , vol.17 , pp. 3115-3124
    • Shen, S.X.1    Weaver, Z.2    Xu, X.3
  • 31
    • 0033603440 scopus 로고    scopus 로고
    • BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair
    • Abbott DW, Thompson ME, Robinson-Benion C, Tomlinson G, Jensen RA, Holt JT. BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair. J Biol Chem 1999;274:18808-18812.
    • (1999) J Biol Chem , vol.274 , pp. 18808-18812
    • Abbott, D.W.1    Thompson, M.E.2    Robinson-Benion, C.3    Tomlinson, G.4    Jensen, R.A.5    Holt, J.T.6
  • 33
    • 0032521537 scopus 로고    scopus 로고
    • BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II)
    • Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II). Cancer Res 1998;58:1120-1123.
    • (1998) Cancer Res , vol.58 , pp. 1120-1123
    • Husain, A.1    He, G.2    Venkatraman, E.S.3    Spriggs, D.R.4
  • 34
    • 0034604716 scopus 로고    scopus 로고
    • The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
    • Bhattacharyya A, Ear US, Koller BH, Weichselbaum RR, Bishop DK. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 2000;275:23899-23903.
    • (2000) J Biol Chem , vol.275 , pp. 23899-23903
    • Bhattacharyya, A.1    Ear, U.S.2    Koller, B.H.3    Weichselbaum, R.R.4    Bishop, D.K.5
  • 35
    • 0024489926 scopus 로고
    • Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors
    • Geisinger KR, Kute TE, Pettenati MJ, et al. Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors. Cancer 1989;63:280-288.
    • (1989) Cancer , vol.63 , pp. 280-288
    • Geisinger, K.R.1    Kute, T.E.2    Pettenati, M.J.3
  • 37
    • 0032508294 scopus 로고    scopus 로고
    • Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
    • Powles T, Eeles R, Ashley S, et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 1998;352:98-101.
    • (1998) Lancet , vol.352 , pp. 98-101
    • Powles, T.1    Eeles, R.2    Ashley, S.3
  • 38
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
    • Fisher B, Costantino JP, Wickerham DL, et al. Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998;90:1371-1388.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3
  • 39
    • 0032188956 scopus 로고    scopus 로고
    • Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers
    • Osin P, Gusterson BA, Philp E, et al. Predicted anti-oestrogen resistance in BRCA-associated familial breast cancers. Eur J Cancer 1998;34:1683-1686.
    • (1998) Eur J Cancer , vol.34 , pp. 1683-1686
    • Osin, P.1    Gusterson, B.A.2    Philp, E.3
  • 40
    • 0037148435 scopus 로고    scopus 로고
    • Estimates of the likely prophylactic effect of tamoxifen in women with high risk BRCA1 and BRCA2 mutations
    • Duffy SW, Nixon RM. Estimates of the likely prophylactic effect of tamoxifen in women with high risk BRCA1 and BRCA2 mutations. Br J Cancer 2002;86:218-221.
    • (2002) Br J Cancer , vol.86 , pp. 218-221
    • Duffy, S.W.1    Nixon, R.M.2
  • 41
    • 0035219808 scopus 로고    scopus 로고
    • Tamoxifen and breast cancer risk in women harboring a BRCA1 germline mutation: Computed efficacy, effectiveness, and impact
    • Eisinger F, Charafe-Jauffret E, Jacquemier J, Birnbaum D, Julian-Reynier C, Sobol H. Tamoxifen and breast cancer risk in women harboring a BRCA1 germline mutation: Computed efficacy, effectiveness, and impact. Int J Oncol 2001;18:5-10.
    • (2001) Int J Oncol , vol.18 , pp. 5-10
    • Eisinger, F.1    Charafe-Jauffret, E.2    Jacquemier, J.3    Birnbaum, D.4    Julian-Reynier, C.5    Sobol, H.6
  • 42
    • 0035804228 scopus 로고    scopus 로고
    • Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
    • Fan S, Ma YX, Wang C, et al. Role of direct interaction in BRCA1 inhibition of estrogen receptor activity. Oncogene 2001;20:77-87.
    • (2001) Oncogene , vol.20 , pp. 77-87
    • Fan, S.1    Ma, Y.X.2    Wang, C.3
  • 43
    • 0036141456 scopus 로고    scopus 로고
    • p300 modulates the BRCA1 inhibition of estrogen receptor activity
    • Fan S, Ma YX, Wang C, et al. p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res 2002;62:141-151.
    • (2002) Cancer Res , vol.62 , pp. 141-151
    • Fan, S.1    Ma, Y.X.2    Wang, C.3
  • 44
    • 0028960025 scopus 로고
    • Somatic mutations in the BRCA1 gene in sporadic ovarian tumours
    • Merajver SD, Pham TM, Caduff RF, et al. Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. Nat Genet 1995;9:439.
    • (1995) Nat Genet , vol.9 , pp. 439
    • Merajver, S.D.1    Pham, T.M.2    Caduff, R.F.3
  • 45
    • 0037567703 scopus 로고    scopus 로고
    • Ovarian cancer associated with inherited mutations in BRCA1 or BRCA2
    • Swisher E. Ovarian cancer associated with inherited mutations in BRCA1 or BRCA2. Curr Womens Health Rep 2003;3:27-32.
    • (2003) Curr Womens Health Rep , vol.3 , pp. 27-32
    • Swisher, E.1
  • 47
    • 0035181465 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen-induced apoptosis
    • Mandlekar S, Kong AN. Mechanisms of tamoxifen-induced apoptosis. Apoptosis 2001;6:469-477.
    • (2001) Apoptosis , vol.6 , pp. 469-477
    • Mandlekar, S.1    Kong, A.N.2
  • 48
    • 0035939373 scopus 로고    scopus 로고
    • Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): Structure-requirement of hydroxyanthraquinones for estrogenic activity
    • Matsuda H, Shimoda H, Morikawa T, Yoshikawa M. Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): Structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorg Med Chem Lett 2001;11:1839-1842.
    • (2001) Bioorg Med Chem Lett , vol.11 , pp. 1839-1842
    • Matsuda, H.1    Shimoda, H.2    Morikawa, T.3    Yoshikawa, M.4
  • 49
    • 0030983424 scopus 로고    scopus 로고
    • Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma
    • Singh UV, Udupa N. Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma. Indian J Physiol Pharmacol 1997;41:171-175.
    • (1997) Indian J Physiol Pharmacol , vol.41 , pp. 171-175
    • Singh, U.V.1    Udupa, N.2
  • 50
    • 0031427002 scopus 로고    scopus 로고
    • Antitumor and antifertility activities of plumbagin controlled release formulations
    • Kini DP, Pandey S, Shenoy BD, et al. Antitumor and antifertility activities of plumbagin controlled release formulations. Indian J Exp Biol 1997;35:374-379.
    • (1997) Indian J Exp Biol , vol.35 , pp. 374-379
    • Kini, D.P.1    Pandey, S.2    Shenoy, B.D.3
  • 51
    • 0030276749 scopus 로고    scopus 로고
    • Niosomal plumbagin with reduced toxicity and improved anticancer activity in BALB/C mice
    • Naresh RA, Udupa N, Devi PU. Niosomal plumbagin with reduced toxicity and improved anticancer activity in BALB/C mice. J Pharm Pharmacol 1996;48:1128-1132.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 1128-1132
    • Naresh, R.A.1    Udupa, N.2    Devi, P.U.3
  • 52
    • 0019127329 scopus 로고
    • Plumbagin: A study of its anticancer, antibacterial, and antifungal properties
    • Krishnaswamy M, Purushothaman KK. Plumbagin: A study of its anticancer, antibacterial, and antifungal properties. Indian J Exp Biol 1980;18:876-877.
    • (1980) Indian J Exp Biol , vol.18 , pp. 876-877
    • Krishnaswamy, M.1    Purushothaman, K.K.2
  • 53
    • 0035916938 scopus 로고    scopus 로고
    • Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation
    • Wang H, Mao Y, Chen AY, Zhou N, LaVoie EJ, Liu LF. Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation. Biochemistry 2001;40:3316-3323.
    • (2001) Biochemistry , vol.40 , pp. 3316-3323
    • Wang, H.1    Mao, Y.2    Chen, A.Y.3    Zhou, N.4    LaVoie, E.J.5    Liu, L.F.6
  • 54
    • 0035895973 scopus 로고    scopus 로고
    • Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization
    • Dietze EC, Caldwell LE, Grupin SL, Mancini M, Seewaldt VL. Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization. J Biol Chem 2001;276:5384-5394.
    • (2001) J Biol Chem , vol.276 , pp. 5384-5394
    • Dietze, E.C.1    Caldwell, L.E.2    Grupin, S.L.3    Mancini, M.4    Seewaldt, V.L.5
  • 55
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • Susin SA, Lorenzo HK, Zamzami N, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999;397:441-446.
    • (1999) Nature , vol.397 , pp. 441-446
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3
  • 56
    • 12244268624 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
    • Cande C, Cecconi F, Dessen P, Kroemer G. Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death? J Cell Sci 2002;115:4727-4734.
    • (2002) J Cell Sci , vol.115 , pp. 4727-4734
    • Cande, C.1    Cecconi, F.2    Dessen, P.3    Kroemer, G.4
  • 57
    • 0035967169 scopus 로고    scopus 로고
    • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
    • Joza N, Susin SA, Daugas E, et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001;410:549-554.
    • (2001) Nature , vol.410 , pp. 549-554
    • Joza, N.1    Susin, S.A.2    Daugas, E.3
  • 58
    • 0035078404 scopus 로고    scopus 로고
    • Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor
    • Loeffler M, Daugas E, Susin SA, et al. Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J 2001;15:758-767.
    • (2001) FASEB J , vol.15 , pp. 758-767
    • Loeffler, M.1    Daugas, E.2    Susin, S.A.3
  • 59
    • 0034051493 scopus 로고    scopus 로고
    • Establishment and characterization of a breast cell strain containing a BRCA1 185delAG mutation
    • Annab LA, Terry L, Cable PL, et al. Establishment and characterization of a breast cell strain containing a BRCA1 185delAG mutation. Gynecol Oncol 2000;77:121-128.
    • (2000) Gynecol Oncol , vol.77 , pp. 121-128
    • Annab, L.A.1    Terry, L.2    Cable, P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.