Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation

Journal of Cell Biology

Volumn 164, Issue 1, 2004, Pages 89-96

  Scott, Clare L ^a,c   Schuler, Martin ^b,d   Marsden, Vanessa S ^a   Egle, Alex ^a,e   Pellegrini, Marc ^a   Nesic, Dobrila ^a,f   Gerondakis, Steve ^a   Nutt, Stephen L ^a   Green, Douglas R ^b   Strasser, Andreas ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^e UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^f UNIVERSITY OF BERN   (Switzerland)

Author keywords

Apaf 1; Apoptosis; Bcl 2; Cancer; Caspase

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 9; IMMUNOGLOBULIN HEAVY CHAIN; MYC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER INHIBITION; CARCINOGENESIS; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; EMBRYO CELL; ENZYME ACTIVITY; FIBROBLAST; LETHALITY; LIVER CELL; LYMPHOMA; MOUSE; NONHUMAN; ONCOGENE C MYC; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSGENE;

ANIMALS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 9; CASPASES; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; FETUS; FIBROBLASTS; HEPATOCYTES; INCIDENCE; LYMPHOMA; MICE; MICE, KNOCKOUT; PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; RADIATION CHIMERA; TRANSGENES; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; DROMAIUS NOVAEHOLLANDIAE;

EID: 0346492579     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200310041     Document Type: Article

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