메뉴 건너뛰기




Volumn 99, Issue 1, 2004, Pages 29-37

Exogenous activation of δ- and κ-opioid receptors affords cardioprotection in isolated murine heart

Author keywords

G protein coupled receptor; Ischemia reperfusion; Mouse; Opioid, stunning

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; 7 BENZYLIDENENALTREXONEMALEATE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; LACTATE DEHYDROGENASE; MORPHINE; NORBINALTORPHIMINE; OPIATE AGONIST; OPIATE RECEPTOR; PENTOBARBITAL; UNCLASSIFIED DRUG;

EID: 0346368469     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-003-0430-y     Document Type: Article
Times cited : (42)

References (46)
  • 1
    • 0034111658 scopus 로고    scopus 로고
    • Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: Implications for ischemic preconditioning
    • Aitchison KA, Baxter GF, Awan MM, Smith RM, Yellon DM, Opie LH (2000) Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: Implications for ischemic preconditioning. Basic Res Cardiol 95: 1-10
    • (2000) Basic Res Cardiol , vol.95 , pp. 1-10
    • Aitchison, K.A.1    Baxter, G.2    Awan, M.M.3    Smith, R.M.4    Yellon, D.M.5    Opie, L.H.6
  • 2
    • 85099487670 scopus 로고    scopus 로고
    • Delta opioid receptor stimulation mimics ischemic preconditioning in human heart muscle
    • Bell SP, Sack MN, Patel A, Opie LH, Yellon DM (2001) Delta opioid receptor stimulation mimics ischemic preconditioning in human heart muscle. J Am Coll Cardiol 36: 296-302
    • (2001) J Am Coll Cardiol , vol.36 , pp. 296-302
    • Bell, S.P.1    Sack, M.N.2    Patel, A.3    Opie, L.H.4    Yellon, D.M.5
  • 5
    • 0029054253 scopus 로고
    • Stereospecific blocking effects of naloxone against hemodynamic compromise and ventricular dysfunction due to myocardial ischemia and reperfusion
    • Chen YT, Lin CJ, Lee AY, Chen JS, Hwang DS (1995) Stereospecific blocking effects of naloxone against hemodynamic compromise and ventricular dysfunction due to myocardial ischemia and reperfusion. Int J Cardiol 50: 125-129
    • (1995) Int J Cardiol , vol.50 , pp. 125-129
    • Chen, Y.T.1    Lin, C.J.2    Lee, A.Y.3    Chen, J.S.4    Hwang, D.S.5
  • 6
    • 0343963740 scopus 로고    scopus 로고
    • Gender differences in the cardiovascular responses to morphine and naloxone in spina rats
    • Cruz SL, Rodriguez-Manzo G (2000) Gender differences in the cardiovascular responses to morphine and naloxone in spina rats. Eur J Pharmacol 397: 121-128
    • (2000) Eur J Pharmacol , vol.397 , pp. 121-128
    • Cruz, S.L.1    Rodriguez-Manzo, G.2
  • 7
    • 0033913629 scopus 로고    scopus 로고
    • Opioid-induced cardioprotection against myocardial infarction and arrhythmias: Mitochondrial versus sarcolemmal ATP-sensitive potassium channels
    • Fryer RM, Hsu AK, Nagase H, Gross GJ (2000) Opioid-induced cardioprotection against myocardial infarction and arrhythmias: Mitochondrial versus sarcolemmal ATP-sensitive potassium channels. J Pharmacol Exp Ther 294: 451-457
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 451-457
    • Fryer, R.M.1    Hsu, A.K.2    Nagase, H.3    Gross, G.J.4
  • 9
    • 0025049133 scopus 로고
    • Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents
    • Gross RA, Moises HC, Uhler MD, Macdonald RL (1990) Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents. Proc Natl Acad Sci USA 87: 7025-7029
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7025-7029
    • Gross, R.A.1    Moises, H.C.2    Uhler, M.D.3    Macdonald, R.L.4
  • 10
    • 0036132238 scopus 로고    scopus 로고
    • Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells
    • Hayashi T, Tsao LI, Su TP (2002) Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala(2),D-Leu(5)]enkephalin in PC12 cells. Synapse 43: 86-94
    • (2002) Synapse , vol.43 , pp. 86-94
    • Hayashi, T.1    Tsao, L.I.2    Su, T.P.3
  • 11
    • 0035196903 scopus 로고    scopus 로고
    • Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart
    • Headrick JP, Peart J, Hack B, Flood A, Maherne GP (2001) Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart. Exp Physiol 86: 703-716
    • (2001) Exp Physiol , vol.86 , pp. 703-716
    • Headrick, J.P.1    Peart, J.2    Hack, B.3    Flood, A.4    Maherne, G.P.5
  • 12
    • 0035001955 scopus 로고    scopus 로고
    • Protection of cardiac myocytes via delta(1)-opioid receptors, protein kinase C, and mitochondrial K(ATP) channels
    • Huh J, Gross GJ, Nagase H, Liang BT (2001) Protection of cardiac myocytes via delta(1)-opioid receptors, protein kinase C, and mitochondrial K(ATP) channels. Am J Physiol Heart Circ Physiol 280: H377-H383
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Huh, J.1    Gross, G.J.2    Nagase, H.3    Liang, B.T.4
  • 13
    • 0036828161 scopus 로고    scopus 로고
    • D-pro(2)-endomorphin-1 and D-pro(2)-endomorphin-2, respectively, attenuate the antinociception induced by endomorphin-1 and endomorphin-2 given intrathecally in the mouse
    • Hung KC, Wu HE, Mizoguchi H, Sakurada S, Okayama T, Fujimura T, Murayama K, Sakurada T, Fujimoto JM, Tseng LF (2002) D-pro(2)-endomorphin-1 and D-pro(2)-endomorphin-2, respectively, attenuate the antinociception induced by endomorphin-1 and endomorphin-2 given intrathecally in the mouse. J Pharmacol Exp Ther 303: 874-879
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 874-879
    • Hung, K.C.1    Wu, H.E.2    Mizoguchi, H.3    Sakurada, S.4    Okayama, T.5    Fujimura, T.6    Murayama, K.7    Sakurada, T.8    Fujimoto, J.M.9    Tseng, L.F.10
  • 14
    • 0032563656 scopus 로고
    • Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats
    • Kwok EH, Dun NJ (1995) Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats. Brain Res 803: 204-207
    • (1995) Brain Res , vol.803 , pp. 204-207
    • Kwok, E.H.1    Dun, N.J.2
  • 15
    • 0034893945 scopus 로고    scopus 로고
    • Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage
    • Liu B, Qin L, Yang SN, Wilson BC, Liu Y, Hong JS (2001) Femtomolar concentrations of dynorphins protect rat mesencephalic dopaminergic neurons against inflammatory damage. J Pharmacol Exp Ther 298: 1133-1141
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1133-1141
    • Liu, B.1    Qin, L.2    Yang, S.N.3    Wilson, B.C.4    Liu, Y.5    Hong, J.S.6
  • 16
    • 0029153641 scopus 로고
    • Characterization of the opioid receptor subtypes mediating the negative inotropic effects of DAMGO, DPDPE and U-50, 488H in isolated human right atria strips
    • Llobell F, Laorden ML (1995) Characterization of the opioid receptor subtypes mediating the negative inotropic effects of DAMGO, DPDPE and U-50, 488H in isolated human right atria strips. Neuropeptides 29: 115-119
    • (1995) Neuropeptides , vol.29 , pp. 115-119
    • Llobell, F.1    Laorden, M.L.2
  • 17
    • 0031785918 scopus 로고    scopus 로고
    • Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
    • Miki T, Cohen MV, Downey JM (1998) Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits. Mol Cell Biochem 186: 3-12
    • (1998) Mol Cell Biochem , vol.186 , pp. 3-12
    • Miki, T.1    Cohen, M.V.2    Downey, J.M.3
  • 19
    • 0031730347 scopus 로고    scopus 로고
    • Rational drug design and synthesis of a highly selective nonpeptide delta-opioid agonist, (4aS*, 12aR*)-4a-(3-hydroxyphenyl)-2-methyl- 1,2,3,4a,5,12,12a-octahydropyrido[3,4-b]acridine (TAN-67)
    • Nagase H, Kawai K, Hayakawa J, Wakita H, Mizusuna A, Matsuura H, Tajima C, Takezawa Y, Endoh T (1998) Rational drug design and synthesis of a highly selective nonpeptide delta-opioid agonist, (4aS*, 12aR*)-4a-(3-hydroxyphenyl)-2-methyl- 1,2,3,4a,5,12,12a-octahydropyrido[3,4-b]acridine (TAN-67). Chem Pharm Bull (Tokyo) 46: 1695-1702
    • (1998) Chem Pharm Bull (Tokyo) , vol.46 , pp. 1695-1702
    • Nagase, H.1    Kawai, K.2    Hayakawa, J.3    Wakita, H.4    Mizusuna, A.5    Matsuura, H.6    Tajima, C.7    Takezawa, Y.8    Endoh, T.9
  • 20
    • 0035123941 scopus 로고    scopus 로고
    • Morphine enhances myofilament CA(2+) sensitivity in intact guinea pig beating hearts
    • Nakae Y, Fujita S, Namiki A (2001) Morphine enhances myofilament CA(2+) sensitivity in intact guinea pig beating hearts. Anesth Analg 92: 602-608
    • (2001) Anesth Analg , vol.92 , pp. 602-608
    • Nakae, Y.1    Fujita, S.2    Namiki, A.3
  • 21
    • 0005353339 scopus 로고
    • Mu and delta receptors belong to a family of receptors that are coupled to potassium channels
    • North RA, Williams JT, Surprenant A, Christie MJ (1987) Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. Proc Natl Acad Sci USA 84: 5487-5491
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5487-5491
    • North, R.A.1    Williams, J.T.2    Surprenant, A.3    Christie, M.J.4
  • 22
    • 0034920183 scopus 로고    scopus 로고
    • BW373U86, a delta opioid agonist, partially mediates delayed cardioprotection via a free radical mechanism that is independent of opioid receptor stimulation
    • Patel HH, Hsu A, Moore J, Gross GJ (2001) BW373U86, a delta opioid agonist, partially mediates delayed cardioprotection via a free radical mechanism that is independent of opioid receptor stimulation. J Mol Cell Cardiol 33:1455-1465
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1455-1465
    • Patel, H.H.1    Hsu, A.2    Moore, J.3    Gross, G.J.4
  • 23
    • 0033673143 scopus 로고    scopus 로고
    • Intrinsic A (1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts
    • Peart J, Headrick JP (2000) Intrinsic A (1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts. Am J Physiol Heart Circ Physiol 279: H2166-H2175
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Peart, J.1    Headrick, J.P.2
  • 25
    • 0026515794 scopus 로고
    • Cardiovascular actions of the kappa-agonist, U-50,488H, in the absence and presence of opioid receptor blockade
    • Pugsley MK, Penz WP, Walker MJ, Wong TM (1992) Cardiovascular actions of the kappa-agonist, U-50,488H, in the absence and presence of opioid receptor blockade. Br J Pharmacol 105: 521-526
    • (1992) Br J Pharmacol , vol.105 , pp. 521-526
    • Pugsley, M.K.1    Penz, W.P.2    Walker, M.J.3    Wong, T.M.4
  • 26
    • 0031647339 scopus 로고    scopus 로고
    • Sodium channel-blocking properties of spiradoline, a kappa receptor agonist, are responsible for its antiarrhythmic action in the rat
    • Pugsley MK, Saint DA, Hayes ES, Kramer D, Walker MJ (1998) Sodium channel-blocking properties of spiradoline, a kappa receptor agonist, are responsible for its antiarrhythmic action in the rat. J Cardiovasc Pharmacol 32: 863-874
    • (1998) J Cardiovasc Pharmacol , vol.32 , pp. 863-874
    • Pugsley, M.K.1    Saint, D.A.2    Hayes, E.S.3    Kramer, D.4    Walker, M.J.5
  • 27
    • 0028006303 scopus 로고
    • Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors
    • Raynor K, Kong H, Chen Y, Yasuda K, Yu L, Bell GI, Reisine T (1994) Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol 45: 330-334
    • (1994) Mol Pharmacol , vol.45 , pp. 330-334
    • Raynor, K.1    Kong, H.2    Chen, Y.3    Yasuda, K.4    Yu, L.5    Bell, G.I.6    Reisine, T.7
  • 28
    • 0035297571 scopus 로고    scopus 로고
    • Stimulation of mu and delta-opiate receptors and tolerance of isolated heart to oxidative stress: The role of NO-synthase
    • Rebrova TY, Maslov LN, Lishmanov AY, Tam SV (2001) Stimulation of mu and delta-opiate receptors and tolerance of isolated heart to oxidative stress: The role of NO-synthase. Biochemistry (Mosc) 66: 422-428
    • (2001) Biochemistry (Mosc) , vol.66 , pp. 422-428
    • Rebrova, T.Y.1    Maslov, L.N.2    Lishmanov, A.Y.3    Tam, S.V.4
  • 29
    • 0031963848 scopus 로고    scopus 로고
    • A comparison of the effects of fentanyl and propofol on left ventricular contractility during myocardial stunning
    • Ross S, Munoz H, Piriou V, Ryder WA, Foex P (1998) A comparison of the effects of fentanyl and propofol on left ventricular contractility during myocardial stunning. Acta Anaesthesiol Scand 42: 23-31
    • (1998) Acta Anaesthesiol Scand , vol.42 , pp. 23-31
    • Ross, S.1    Munoz, H.2    Piriou, V.3    Ryder, W.A.4    Foex, P.5
  • 30
    • 0026478138 scopus 로고
    • Endogenous prostacyclin preserves myocardial function and endothelium-derived nitric oxide formation in myocardial ischemia
    • Schror K, Woditsch I (1992) Endogenous prostacyclin preserves myocardial function and endothelium-derived nitric oxide formation in myocardial ischemia. Agents Actions (Suppl) 37: 312-319
    • (1992) Agents Actions (Suppl) , vol.37 , pp. 312-319
    • Schror, K.1    Woditsch, I.2
  • 31
    • 0035058592 scopus 로고    scopus 로고
    • Opioids and cardioprotection
    • Schultz JE, Gross GJ (2001) Opioids and cardioprotection. Pharmacol Ther 89: 123-137
    • (2001) Pharmacol Ther , vol.89 , pp. 123-137
    • Schultz, J.E.1    Gross, G.J.2
  • 32
    • 0343041621 scopus 로고    scopus 로고
    • Ischemic preconditioning in the intact rat heart is mediated by delta1 - But not mu- or kappa-opioid receptors
    • Schultz JE, Hsu AK, Gross GJ (1998) Ischemic preconditioning in the intact rat heart is mediated by delta1 - But not mu- or kappa-opioid receptors. Circulation 97: 1282-1289
    • (1998) Circulation , vol.97 , pp. 1282-1289
    • Schultz, J.E.1    Hsu, A.K.2    Gross, G.J.3
  • 33
    • 0031919982 scopus 로고    scopus 로고
    • TAN-67, a delta 1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels
    • Schultz J El-J, Hsu AK, Nagase H, Gross GJ (1998) TAN-67, a delta 1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels. Am J Physiol 274: H909-H914
    • (1998) Am J Physiol , vol.274
    • Schultz, J.E.-J.1    Hsu, A.K.2    Nagase, H.3    Gross, G.J.4
  • 34
    • 0029039111 scopus 로고
    • Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts
    • Schultz JE, Rose E, Yao Z, Gross GJ (1995) Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts. Am J Physiol 268: H2157-H2161
    • (1995) Am J Physiol , vol.268
    • Schultz, J.E.1    Rose, E.2    Yao, Z.3    Gross, G.J.4
  • 35
    • 0035026146 scopus 로고    scopus 로고
    • Role of endogenous opioids in ischemic preconditioning but not in short-term hibernation in pigs
    • Schultz R, Gress P, Heusch G (2001) Role of endogenous opioids in ischemic preconditioning but not in short-term hibernation in pigs. Am J Physiol Heart Circ Physiol 280: H2175-H2181
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Schultz, R.1    Gress, P.2    Heusch, G.3
  • 37
    • 16944367171 scopus 로고    scopus 로고
    • Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+]i in myocytes
    • Sheng JZ, Wong NS, Wang HX, Wong TM (1997) Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+]i in myocytes. Am J Physiol 272: C560-C564
    • (1997) Am J Physiol , vol.272
    • Sheng, J.Z.1    Wong, N.S.2    Wang, H.X.3    Wong, T.M.4
  • 38
    • 0033256817 scopus 로고    scopus 로고
    • Met5-enkephalin protects isolated adult rabbit cardiomyocytes via delta-opioid receptors
    • Takasaki Y, Wolff RA, Chien GL, Van Winkle DM (1999) Met5-enkephalin protects isolated adult rabbit cardiomyocytes via delta-opioid receptors. Am J Physiol 277: H2442-H2450
    • (1999) Am J Physiol , vol.277
    • Takasaki, Y.1    Wolff, R.A.2    Chien, G.L.3    Van Winkle, D.M.4
  • 39
    • 0026315631 scopus 로고
    • Kappa-opioid peptide receptor stimulation increases cytosolic pH and myofilament responsiveness to Ca2+ in cardiac myocytes
    • Ventura C, Capogrossi MC, Spurgeon HA, Lakatta EG (1991) Kappa-opioid peptide receptor stimulation increases cytosolic pH and myofilament responsiveness to Ca2+ in cardiac myocytes. Am J Physiol 261: H1671-H1674
    • (1991) Am J Physiol , vol.261
    • Ventura, C.1    Capogrossi, M.C.2    Spurgeon, H.A.3    Lakatta, E.G.4
  • 40
    • 0026504555 scopus 로고
    • Kappa and delta opioid receptor stimulation affects cardiac myocyte function and Ca2+ release from an intracellular pool in myocytes and neurons
    • Ventura C, Spurgeon H, Lakatta EG, Guarnieri C, Capogrossi MC (1992) Kappa and delta opioid receptor stimulation affects cardiac myocyte function and Ca2+ release from an intracellular pool in myocytes and neurons. Circ Res 70: 66-81
    • (1992) Circ Res , vol.70 , pp. 66-81
    • Ventura, C.1    Spurgeon, H.2    Lakatta, E.G.3    Guarnieri, C.4    Capogrossi, M.C.5
  • 41
    • 0034997753 scopus 로고    scopus 로고
    • Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats
    • Wang GY, Wu S, Pei JM, Yu XC, Wong TM (2001) Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats. Am J Physiol Heart Circ Physiol 280: H384-H391
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Wang, G.Y.1    Wu, S.2    Pei, J.M.3    Yu, X.C.4    Wong, T.M.5
  • 42
    • 0034768126 scopus 로고    scopus 로고
    • Protein kinase C-epsilon is a triger of delayed cardioprotection against myocardial ischemia of kappa-opioid receptor stimulation in rat ventricular myocytes
    • Wang GY, Zhou JJ, Shan J, Wong TM (2001) Protein kinase C-epsilon is a triger of delayed cardioprotection against myocardial ischemia of kappa-opioid receptor stimulation in rat ventricular myocytes. J Pharmacol Exp Ther 299: 603-610
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 603-610
    • Wang, G.Y.1    Zhou, J.J.2    Shan, J.3    Wong, T.M.4
  • 43
    • 0031694524 scopus 로고    scopus 로고
    • Diminution of contractile response by kappa-opioid receptor agonists in isolated rat ventricular cardiomyocytes is mediated via a pertussis toxin-sensitive G protein
    • Wenzlaff H, Stein B, Teschemacher H (1998) Diminution of contractile response by kappa-opioid receptor agonists in isolated rat ventricular cardiomyocytes is mediated via a pertussis toxin-sensitive G protein. Naunyn Schmiedebergs Arch Pharmacol 358: 360-366
    • (1998) Naunyn Schmiedebergs Arch Pharmacol , vol.358 , pp. 360-366
    • Wenzlaff, H.1    Stein, B.2    Teschemacher, H.3
  • 44
    • 0029801688 scopus 로고    scopus 로고
    • Multiplicity of kappa opioid receptor binding in the rat cardiac sarcolemma
    • Zhang WM, Jin WQ, Wong TM (1996) Multiplicity of kappa opioid receptor binding in the rat cardiac sarcolemma. J Mol Cell Cardiol 28: 1547-1554
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 1547-1554
    • Zhang, W.M.1    Jin, W.Q.2    Wong, T.M.3
  • 45
    • 0033083472 scopus 로고    scopus 로고
    • Effects of U50488 and bremazocine on [Ca2+]i and cAMP in naive and tolerant rat ventricular myocytes: Evidence of kappa opioid receptor multiplicity in the heart
    • Zhang WM, Su S, Yu XC, Wang HX, Bian IS, Wong TM (1999) Effects of U50488 and bremazocine on [Ca2+]i and cAMP in naive and tolerant rat ventricular myocytes: Evidence of kappa opioid receptor multiplicity in the heart. J Mol Cell Cardiol 31: 355-362
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 355-362
    • Zhang, W.M.1    Su, S.2    Yu, X.C.3    Wang, H.X.4    Bian, I.S.5    Wong, T.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.