Rational drug design and synthesis of a highly selective nonpeptide δ- opioid agonist, (4aS*,12aR*)-4a-(3-hydroxyphenyl)-2-methyl- 1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b] acridine (TAN-67)

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 11, 1998, Pages 1695-1702

  Nagase, Hiroshi ^a   Kawai, Koji ^a   Hayakawa, Jun ^a   Wakita, Hisanori ^a   Mizusuna, Akira ^a   Matsuura, Hirotoshi ^a   Tajima, Chiko ^a   Takezawa, Yuko ^a   Endoh, Takashi ^a  

^a TORAY INDUSTRIES INC   (Japan)

Author keywords

Accessory site; Message address concept; TAN 67; opioid agonist; 1 selective agonist

Indexed keywords

1,2,3,4,4A,5,12,12AALPHA OCTAHYDRO 4AALPHA (3 HYDROXYPHENYL) 2 METHYLQUINOLINO[2,3 G]ISOQUINOLINE; DELTA OPIATE RECEPTOR AGONIST; NALTREXONE DERIVATIVE; NALTRINDOLE;

ANIMAL TISSUE; ARTICLE; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; RECEPTOR AFFINITY;

EID: 0031730347     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.1695     Document Type: Article

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