κ- but not δ-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 1 49-1, 2001, Pages

  Wang, Guan Ying ^a   Wu, Song ^a   Pei, Jian Ming ^a   Yu, Xiao Chun ^a   Wong, Tak Ming ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

ATP sensitive potassium channel; Opioid receptor; Protein kinase C

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; CALPHOSTIN C; CHELERYTHRINE; DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; GLIBENCLAMIDE; KAPPA OPIATE RECEPTOR; NALTRINDOLE; NORBINALTORPHIMINE; POTASSIUM CHANNEL; PROTEIN KINASE C INHIBITOR;

ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE FIBER MEMBRANE; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0034997753     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.1.h384     Document Type: Article

References (61)

1. Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: Implications for ischemic preconditioning
2. Preconditioning of isolated rabbit cardiomyocytes: Induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C a protein kinase C inhibitor
3. Blockade of ischemic preconditioning in dogs by the novel ATP-dependent potassium channel antagonist sodium 5-hydroxydecanoate
4. Effects of κ-opioid receptor stimulation in the heart and the involvement of protein kinase C
5. Phospholipase C inhibitors attenuate arrhythmias induced by kappa-receptor stimulation in the isolated rat heart
6. Norbinaltorphimine: Antagonist profile at opioid receptors
7. Effects of glibenclamide on ventricular arrhythmias and cardiac function in ischemia and reperfusion in isolated rat heart
8. ATP in the isolated rat heart
9. Toward the heart of ischemic precoditioning
10. ATP channels
11. Role of bradykinin in protection of ischemic preconditioning in rabbit hearts
12. Blockade of the ATP-sensitive potassium channels prevents myocardial preconditioning
13. Effect of en torphins on heart rate and blood pressure in adult dogs
14. ATP channel by glyburide and 5-hydroxydecanoic acid
15. Functional couplings of the κ-opioid receptors with the G-protein activated K channel
16. 1-13 on cardiac rhythm and cyclic adenosine monophosphate (cAMP) levels in the isolated perfused rat heart
17. Does protein kinase C play a role in i-chemic preconditioning in rat hearts?
18. ATP Channel
19. ATP channels
20. Protein kinase C-induced changes in the stoichiometry of ATP binding activate cardiac ATP-sensitive K′ channels
21. 1 adenosine receptors in rabbit heart
22. Ischemic preconditioning protects against infarction in rat heart
23. Synergistic modulation of ATP-sensitive K currents by protein kinase C and adenosine. Implications for ischemic preconditioning
24. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium
25. Delta-1 opioid agonist acutely increases hypoxic tolerance
26. Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
27. Blockade of ATP-sensitive potassium channels by 5-hydroxydecanoate suppresses monophasic action potential shortening during regional myocardial ischemia
28. Preconditioning with ischemia, a delay of lethal cell injury in ischomic myocardium
29. Opiate receptors: Ligands and methods of study
30. Preconditioning by transient myocardial ischemia confers protection against ischemia-induced ventricular arrhythmias in variant angina
31. The antiarrhythmic effect of ischemic preconditioning in isolated rat heart involves a pertussis toxin sensitive mechanism
32. Structure activity relationship of N17′-substituted nor-binaltorphimine congeners: Role of the N17′ basic group in the interaction with a putative address subsite on the κ opioid receptor
33. Naltrindole, a highly selective and potent non peptide δ-opioid receptor antagonist
34. Preconditioning of cardiac myocytes with calcium
35. 5-Hydroxydecanoate selectively reduces the initial increase in extracellular K′ in ischemic guinea pig heart
36. Modulation of mitochondrial ATP-dependent K′ channels by protein kinase C
37. Kappa 1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum
38. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart
39. ATP channels
40. Evidence for involvement of opioid receptors in ischemic preconditioning in rat heart
41. Ischemic preconditioning and morphine-induced cardioprotection involve the δ-opioid receptor in the intact rat heart
42. 1- but not μ- or κ-opioid receptors
43. i in myocytes
44. Preconditioning of ischemic myocardium: Reperfusion-induced arrhythmias
45. Direct evidence that ischemic preconditioning does not cause protein kinase C translocation in rabbit heart
46. 3H]-U69593 binding sites in the rat heart by receptor binding studies
47. Quantitative analysis of multiple kappa-opioid receptors by selective and nonselective ligand binding in guinea pig spinal cord: Resolution of high and low affinity states of the kappa 2 receptors by a computerized model-fitting technique
48. The role of protein kinase C in ischemia/reperfused preconditioned isolated rat hearts
49. No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine
50. Are ATP sensitive potassium channels involved in the pronounced antiarrhythmic effects of preconditioning?
51. Opioid receptors in rat cardiac sarcolemma: Effects of phenylephrine and isoproterenol
52. U-50,488H, a selective and structurally novel non-μ (κ) opioid agonist
53. Antiarrhythmic effects of preconditioning in anesthetised dogs and rats
54. Chronic morphine treatment reduces the incidence of ventricular arrhythmias in the isolated rat heart induced by dynorphinl-13 or myocardial ischemia and reperfusion
55. Effects of drugs interacting with opioid receptors during normal perfusion or ischemia and reperfusion in the isolated rat heart-an attempt to identify cardiac opioid receptor subtype(s) involved in arrhythmogenesis
56. Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte: Involvement of κ-opioid receptor
57. Decreased affinity of κ-opioid receptor binding during reperfusion following ischemic preconditioning in the rat heart
58. Thrombin activates the sarcolemmal Na -H exchanger: Evidence for a receptor-mediated mechanism involving protein kinase C
59. Anti-arrhythmic effect of kappa-opioid receptor stimulation in the perfused rat heart: Involvement of a cAMP-dependent pathway
60. i and cAMP in naive and tolerant rat ventricular myocytes: Evidence of kappa opioid receptor multiplicity in the heart
61. Direct evidence that initial oxidative stress triggered by preconditioning contributes to second window of protection by endogenous antioxidant enzyme in myocytes