Sodium channel-blocking properties of spiradoline, a κ receptor agonist, are responsible for its antiarrhythmic action in the rat

Journal of Cardiovascular Pharmacology

Volumn 32, Issue 6, 1998, Pages 863-874

  Pugsley, Michael K ^a,c   Saint, David A ^b   Hayes, Eric S ^a,d   Kramer, David ^a   Walker, M J A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c XOMA Corporation   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Antiarrhythmic; Cardiac electrophysiology; Sodium current; U 62,066E (spiradoline); Opioid receptor agonist

Indexed keywords

KAPPA OPIATE RECEPTOR AGONIST; SODIUM CHANNEL; SPIRADOLINE; SPIRADOLINE MESILATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; HEART HEMODYNAMICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031647339     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199812000-00002     Document Type: Article

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