Effects of κ-opioid receptor activation on myocardium

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 281, Issue 2 50-2, 2001, Pages

  Pyle, W G ^a   Lester, J W ^a   Hofmann, P A ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Actomyosin Mg2+ ATPase; ATP; Calcium sensitivity of tension; pH; Protein kinase C

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPRENALINE; KAPPA OPIATE RECEPTOR; MYOSIN ADENOSINE TRIPHOSPHATASE; PHENYLEPHRINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROPRANOLOL; PROTEIN KINASE C;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; INOTROPISM; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0034886330     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.281.2.h669     Document Type: Article

References (46)

1. Myocardial contractile function during ischemia and hypoxia
2. Transmural gradients of left ventricular tissue metabolites after circumflex artery ligation in dogs
3. Cardioprotective actions of potassium channel openers
4. 2
5. ATP channels in the isolated rat heart
6. Protein kinase C isozyme-specific modulation of cyclic AMP-dependent phosphodiesterase in hypertrophic cardiomyopathic hamster hearts
7. Ischaemic preconditoning and contractile function: Studies with normothermic and hypothermic global ischaemia
8. Protein kinase C enhances myosin light-chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells
9. Localization of protein kinase C isozymes in cardiac myocytes
10. Computer programes for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands
11. Ischemic preconditioning inhibits glycolysis and proton production in isolated working rat hearts
12. The colorimetric determination of phosphorus
13. Inhibition of expression of protein kinase C alpha by antisense cDNA inhibits phorbol ester-mediated arachidonate release
14. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit heart
15. Effect of phosphorylation of troponin I and C protein on isometric tension and velocity of unloaded shortening in skinned single cardiac myocytes from rats
16. Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties
17. Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene
18. 2+dependent protein kinase
19. Effects of adenosine and protein kinase C stimulation on mechanical properties of rat cardiac myocytes
20. Phosphorylation of bovine C-protein by protein kinase C
21. Use of firefly luciferase in ATP-related assays of biomass, enzymes, and metabolites
22. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils
23. Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
24. 2+sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy
25. Developmental differences in the stimulation of cardiac myofibrillar Mg(2+)-ATPase activity by calmidazolium
26. Preconditioning with ischaemia: A delay of lethal cell injury in ischemic myocardium
27. 2+-stimulated actomyosin ATPase activity
28. 2+-stimulated MgATPase activity in reconstituted actomyosin and isolated myofibrils, and decreases actin-myosin interactions
29. Regulation of protein phosphorylation by inotropic agents in isolated rat myocardial cells
30. Acidosis antagonizes intracellular calcium response to κ-opioid receptor stimulation in the rat heart
31. Neurohormonal control of calcium sensitivity of myofilaments in rat single heart cells
32. Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes
33. Cardioprotection with κ-opioid receptor stimulation is associated with a slowing of cross-bridge cycling
34. Ischemic preconditioning in the intact rat heart is mediated by delta-1 but not mu- or kappa-opioid receptors
35. Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts
36. Ischemic preconditioning and morphine-induced cardioprotection involve the delta (delta)-opioid receptor in the intact rat heart
37. 1-Adrenergic receptor stimulation decreases maximum shortening velocity of skinned single ventricular myocytes from rats
38. Betaadrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats
39. Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts
40. Effect of α-adrenergic stimulation on activation of protein kinase C and phosphorylation of proteins in intact rabbit hearts
41. Role of protein kinase C in the phosphorylation of cardiac myosin light chain 2
42. 2+ in cardiac myocytes
43. Kappa and delta opioid receptor stimulation affects cardiac myocyte function and Ca release from an intracellular pool in myocytes and neurons
44. Chimera analysis of troponin I domains that influence Ca(2+)-activated myofilament tension in adult cardiac myocytes
45. U50,488H inhibits effects of norepinephrine in rat cardiomyocytes-cross-talk between kappa-opioid and beta-adrenergic receptors
46. Expression of opioid receptors during heart ontogeny in normotensive and hypertensive rats