Role of endogenous opioids in ischemic preconditioning but not in short-term hibernation in pigs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 5 49-5, 2001, Pages

  Schulz, Rainer ^a   Gres, Petra ^a   Heusch, Gerd ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Free energy change; Infarction; Myocardial ischemia

Indexed keywords

BETA ENDORPHIN; NALOXONE; OPIATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART INFARCTION PREVENTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE REPERFUSION; HEMODYNAMICS; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MYOCARDIAL HIBERNATION; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 0035026146     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.5.h2175     Document Type: Article

References (57)

1. Aitchison KA, Baxter GF, Moneeb Awan M, Smith RM, Yellon DM, and Opie LH. Opposing effects on infarction of delta and kappa opioid receptor activation in the isolated rat heart: implications for ischemic preconditioning. Basic Res Cardiol 95: 1-10, 2000.
2. Barancik M, Htun P, Strohm C, Kilian S, and Schaper W. Inhibition of the cardiac p38-MAPK pathway by SB203580 delays ischemic cell death. J Cardiovasc Pharmacol 35: 474-483, 2000.
3. Baxter GF, Goma FM, and Yellon DM. Characterisation of the infarct-limiting effect of delayed preconditioning: time-course and dose-dependency studies in rabbit myocardium. Basic Res Cardiol 92: 159-167, 1997.
4. Behrends M, Schulz R, Post H, Alexandrov A, Belosjorow S, Michel MC, and Heusch G. Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs. Am J Physiol Heart Circ Physiol 279: H1111-H1119, 2000.
5. Bergey JL and Beil ME. Antiarrhythmic evaluation of naloxone against acute coronary occlusion-induced arrhythmias in pigs. Eur J Pharmacol 90: 427-431, 1983.
6. Birincioglu M, Yang XM, Critz SD, Cohen MV, and Downey JM. S-T segment voltage during sequential coronary occlusions is an unreliable marker of preconditioning. Am J Physiol Heart Circ Physiol 277: H2435-H2441, 1999.
7. Bolling SF, Benedict MB, Tramontini NL, Kilgore KS, Harlow HH, Su TP, and Oeltgen PR. Hibernation triggers and myocardial protection. Circulation 98, Suppl 19: II-220-II-224, 1998.
8. Bolling SF, Tramontini NL, Kilgore KS, Su TP, Oeltgen PR, and Harlow HH. Use of "natural" hibernation induction triggers for myocardial protection. Ann Thorac Surg 64: 623-627, 1997.
9. Bradberry JC and Raebel MA. Continuous infusion of naloxone in the treatment of narcotic overdose. Drug Intell Clin Pharmacol 15: 945-950, 1981.
10. Bruce DS, Cope GW, Elam TR, Ruit KA, Oeltgen PR, and Su TP. Opioids and hibernation. I. Effects of naloxone on bear HIT's depression of guinea pig ileum contractility and on induction of summer hibernation in the ground squirrel. Life Sci 41: 2107-2111, 1987.
11. Byrd LD. Cardiovascular effects of naloxone, naltrexone and morphine in the squirrel monkey. Life Sci 32: 391-398, 1983.
12. Cave AC, Collis CS, Downey JM, and Hearse DJ. Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart. Cardiovasc Res 27: 663-668, 1993.
13. Chien GL, Mohtadi K, Wolff RA, and van Winkle DM. Naloxone blockade of myocardial ischemic preconditioning does not require central nervous system participation. Basic Res Cardiol 94: 136-143, 1999.
14. Downey JM. Anti-preconditioning. Basic Res Cardiol 95: 11, 2000.
15. Falcone C, Guasti L, Ochan M, Codega S, Tortorici M, Angoli L, Bergamaschi R, and Montemartini C. Beta-endorphins during coronary angioplasty in patients with silent or symptomatic myocardial ischemia. J Am Coll Cardiol 22: 1614-1620, 1993.
16. Flacke JW, Flacke WE, Bloor BC, and Olewine S. Effects of fentanyl, naloxone, and clonidine on hemodynamics and plasma catecholamine levels in dogs. Anesth Analg 62: 305-313, 1983.
17. Fryer RM, Hsu AK, Eells JT, Nagase H, and Gross GJ. Opioid-induced second window of cardioprotection. Circ Res 84: 846-851, 1999.
18. Gold CG, Cullen DJ, Gonzales S, Houtmeyers D, and Dwyer MJ. Rapid opioid detoxification during general anesthesia. Anesthesiology 91: 1639-1647, 1999.
19. Goto M, Liu Y, Yang XM, Ardell JL, Cohen MV, and Downey JM. Role of bradykinin in protection of ischemic preconditioning in rabbit hearts. Circ Res 77: 611-621, 1995.
20. Guo Y, Wu WJ, Qiu Y, Tang XL, Yang Z, and Bolli R. Demonstration of an early and a late phase of ischemic preconditioning in mice. Am J Physiol 44: H1375-H1387, 1998.
21. Gutstein HB, Rubie EA, Mansour A, Akil H, and Woodgett JR. Opioid effects on mitogen-activated protein kinase signaling cascades. Anesthesiology 87: 1118-1126, 1997.
22. Heusch G. Hibernating myocardium. Physiol Rev 78: 1055-1085, 1998.
23. Heusch G, Post H, Michel MC, Kelm M, and Schulz R. Endogenous nitric oxide and myocardial adaptation to ischemia. Circ Res 87: 146-152, 2000.
24. Heusch G, Rose J, Skyschally A, Post H, and Schulz R. Calcium responsiveness in regional myocardial short-term hibernation and stunning in the in situ porcine heart-inotropic responses to postextrasystolic potentiation and intracoronary calcium. Circulation 93: 1556-1566, 1996.
25. Horton ND, Kaftani DJ, Bruce DS, Bailey EC, Krober AS, Jones JR, Turker M, Khattar N, Su TP, Bolling SF, and Oeltgen PR. Isolation and partial characterization of an opioid-like 88 kDa hibernation-related protein. Comp Biochem Physiol 119: 787-805, 1998.
26. Kato R, Ross S, and Foex P. Fentanyl protects the heart against ischaemic injury via opioid receptors, adenosine Al receptors and KATP channel linked mechanisms in rats. Br J Anaesth 84: 204-214, 2000.
27. Kevelaitis E, Peynet J, Mouas C, Launay JM, and Menasché P. Opening of potassium channels. The common cardioprotective link between preconditioning and natural hibernation? Circulation 99: 3079-3085, 1999.
28. Kienbaum P, Thurauf N, Michel MC, Scherbaum N, Gastpar M, and Peters J. Profound increase in epinephrine concentration in plasma and cardiovascular stimulation after mu-opioid receptor blockade in opioid-addicted patients during barbiturate-induced anesthesia for acute detoxification. Anesthesiology 88: 1154-1161, 1998.
29. Kim SO, Baines CP, Critz SD, Pelech SL, Katz S, Downey JM, and Cohen MV. Ischemia induced activation of heat shock protein 27 kinases and casein kinase 2 in the preconditioned rabbit heart. Biochem Cell Biol 77: 559-567, 1999.
30. Kurita A, Takase B, Uehata A, Sugahara H, Nishioka H, Maruyama T, Satomura K, Mizuno K, and Nakamura H. Differences in plasma beta-endorphin and bradykinin levels between patients with painless or with painful myocardial ischemia. Am Heart J 123: 304-309, 1992.
31. ATP channels. Circ Res 84: 1396-1400, 1999.
32. Martin C, Schulz R, Rose J, and Heusch G. Inorganic phosphate content and free energy change of ATP hydrolysis in regional short-term hibernating myocardium. Cardiouasc Res 39: 318-326, 1998.
33. Maxam-Moore VA, Wilkie DJ, and Woods SL. Analgesics for cardiac surgery patients in critical care: describing current practice. Am J Crit Care 3: 31-39, 1994.
34. Miki T, Cohen MV, and Downey JM. Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits. Mol Cell Biochem 186: 3-12, 1998.
35. Oeltgen PR, Welborn JR, Nuchols PA, Spurrier WA, Bruce DS, and Su TP. Opioids and hibernation. II. Effects of kappa opioid U69593 on induction of hibernation in summer-active ground squirrels by "Hibernation Induction Trigger" (HIT). Life Sci 41: 2115-2110, 1987.
36. Oldroyd KG, Harvey K, Gray CE, Beastall GH, and Cobbe SM. β-Endorphin release in patients after spontaneous and provoked acute myocardial ischaemia. Br Heart J 1992: 230-235, 1999.
37. Ping P, Zhang J, Li RCX, Kong D, Tang XL, Qiu Y, Manchikalapudi S, Auchampach JA, Blacl RG, and Bolli R. PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits. Am J Physiol Heart Circ Physiol 276: H1468-H1481, 1999.
38. Rahimtoola SH. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation 72, Suppl V: V-123-V-135, 1985.
39. Reimer KA, Murry CE, and Jennings RB. Cardiac adaptation to ischemia. Ischemic preconditioning increases myocardial tolerance to subsequent ischemic episodes. Circulation 82: 2266-2268, 1990.
40. Ross J Jr. Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation. Circulation 83: 1076-1083, 1991.
41. Schaper W, Görge G, Winkler B, and Schaper J. The collateral circulation of the heart. Prog Cardiovasc Dis 31: 57-77, 1988.
42. Schultz JEJ, Hsu AK, and Gross GJ. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart. Circ Res 78: 1100-1104, 1996.
43. Schultz JEJ, Hsu AK, and Gross GJ. Ischemic preconditioning in the intact rat heart is mediated by δ1- but not μ- or κ-opioid receptors. Circulation 97: 1282-1289, 1998.
44. ATP channels. Am J Physiol Heart Circ Physiol 274: H909-H914, 1998.
45. Schultz JEJ, Rose E, Yao Z, and Gross GJ. Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts. Am J Physiol Heart Circ Physiol 268: H2157-H2161, 1995.
46. Schultz JJ, Hsu A, and Gross GJ. Ischemic preconditioning is mediated by a peripheral opioid receptor mechanism in the intact rat heart. J Mol Cell Cardiol 29: 1355-1362, 1997.
47. Schulz R, Post H, Vahlhaus C, and Heusch G. Ischemic preconditioning in pigs: a graded phenomenon. Its relation to adenosine and bradykinin. Circulation 98: 1022-1029, 1998.
48. Schulz R, Rose J, and Heusch G. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine. Am J Physiol Heart Circ Physiol 267: H1341-H1352, 1994.
49. Schulz R, Rose J, Post H, and Heusch G. Involvement of endogenous adenosine in ischaemic preconditioning in swine. Pflügers Arch 430: 273-282, 1995.
50. Schulz R, Rose J, Post H, and Heusch G. Regional short-term hibernation in swine does not involve endogenous adenosine or KATP channels. Am J Physiol Heart Circ Physiol 268: H2294-H2301, 1995.
51. Strohm C, Barancik M, v. Brühl ML, Kilian SAR, and Schaper W. Inhibition of the ER-kinase casade by PD98059 and UO126 counteracts ischemic preconditioning in pig myocardium. J Cardiovasc Pharmacol 36: 218-229, 2000.
52. Tomai F, Crea F, Gaspardone A, Versaci F, Ghini AS, Ferri C, Desideri G, Chiariello L, and Gioffré PA. Effects of naloxone on myocardial ischemic preconditioning in humans. J Am Coll Cardiol 33: 1863-1869, 1999.
53. Tsang J and Brush B. Patient-controlled analgesia in postoperative cardiac surgery. Anaesth Intensive Care 27: 464-470, 1999.
54. Vahlhaus C, Schulz R, Post H, Rose J, and Heusch G. Prevention of ischemic preconditioning only by combined inhibition of protein kinase C and protein tyrosine kinase in pigs. J Mol Cell Cardiol 30: 197-209, 1998.
55. Weaver ME, Pantely GA, Bristow JD, and Ladley HD. A quantitative study of the anatomy and distribution of coronary arteries in swine in comparison with other animals and man. Cardiovasc Res 20: 907-917, 1986.
56. White FC and Bloor CM. Coronary collateral circulation in the pig: correlation of collateral flow with coronary bed size. Basic Res Cardiol 76: 189-196, 1981.
57. Yellon DM, Baxter GF, Garcia-Dorado D, Heusch G, and Sumeray MS. Ischaemic preconditioning: present position and future directions. Cardiovasc Res 37: 21-33, 1998.