Poly(ADP-ribosyl)ation, genomic instability, and longevity

Annals of the New York Academy of Sciences

Volumn 908, Issue , 2000, Pages 126-132

  Bürkle, Alexander ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

ALKYLATION; CONFERENCE PAPER; ENZYME ACTIVITY; GENETIC STABILITY; LIFESPAN; LONGEVITY; LYMPHOBLASTOID CELL; MONOCYTE; PROTEIN PROCESSING; SISTER CHROMATID EXCHANGE;

MAMMALIA;

EID: 0033942473     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06641.x     Document Type: Conference Paper

References (29)

1. 1. RATTAN, S.I.S. & O. TOUSSAINT, Eds. 1996. Molecular Gerontology - Research Status and Strategies. Plenum. New York.
2. 2. ALTHAUS, F.R. & C. RICHTER. 1987. ADP-ribosylation of proteins: enzymology and biological significance. Mol. Biol. Biochem. Biophys. 37: 1-126.
3. 3. BÜRKLE, A. 1996. Maintaining the stability of the genome. In Molecular Gerontology -Research Status and Strategies. S.I.S. Rattan & O. Toussaint, Eds. :25-36. Plenum. New York.
4. 4. MOLINETE, M. et al. 1993. The poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in living cells. EMBO J. 12: 2109-2117.
5. 5. TRUCCO, C. et al. 1998. DNA repair defect in poly(ADP-ribose) polymerase deficient cell lines. Nucl. Acids Res. 26: 2644-2649.
6. 6. DANTZER, F. et al. 1999. Role of poly(ADP-ribose) polymerase in base excision repair. Biochimie 81: 69-75.
7. 7. MÉNISSIER-DE MURCIA, J. et al. 1997. Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc. Natl. Acad. Sci. USA 94: 7303-7307.
8. 8. WANG, Z.-Q. et al. 1997. PARP is important for genomic stability but dispensable in apoptosis. Genes Dev. 11: 2347-2358.
9. 9. HELLER, B. et al. 1995. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J. Biol. Chem. 270: 11176-11180.
10. 10. BURKART, V. et al. 1999. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozotocin. Nat. Med. 5: 314-319.
11. 11. ELIASSON, M.J. et al. 1997. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med. 3: 1089-1095.
12. 12. MANDIR, A.S. et al. 1999. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (MPTP)-induced parkinsonism. Proc. Natl. Acad. Sci. USA 96: 5774-5779.
13. 13. SHIEH, W.M. et al. 1998. Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers. J. Biol. Chem. 273: 30069-30072.
14. 14. SMITH, S. et al. 1998. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282: 1484-1487.
15. 15. AMÉ, J.C. et al. 1999. PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase. J. Biol. Chem. 274: 17860-17868.
16. 16. BERGHAMMER, H. et al. 1999. pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans. FEBS Lett. 449: 259-263.
17. 17. JOHANSSON, M. 1999. A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues. Genomics 57: 442-445.
18. 18. GRUBE, K. & A. BÜRKLE. 1992. Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span. Proc. Natl. Acad. Sci. USA 89: 11759-11763.
19. 19. PERO, R.W. et al. 1985. Gamma-radiation induced ADP-ribosyl transferase activity and mammalian longevity. Mutat Res. 142: 69-73.
20. 20. MUIRAS, M.-L. et al. 1998. Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians. J. Mol. Med. 76: 346-354.
21. 21. D'ADDA DI FAGAGNA, F. et al. 1999. Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability. Nat. Genet. 23: 76-80.
22. 22. KÜPPER, J.-H. et al. 1990. Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells. J. Biol. Chem. 265: 18721-18724.
23. 23. VAN GOOL , L. et al. 1997. Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to γ irradiation. Eur. J. Biochem. 244: 15-20.
24. 24. KÜPPER, J.-H. et al. 1995. Trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against γ-irradiation and N-methyl-N′-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyomavirus replicon. Mol. Cell. Biol. 15: 3154-3163.
25. 25. KÜPPER, J.-H. et al. 1996. Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates carcinogen-induced gene amplification in SV40-transformed Chinese hamster cells. Cancer Res. 56: 2715-2717.
26. 26. TATSUMI-MIYAJIMA, J. et al. 1999. Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells. Mol. Cell. Biochem. 193: 31-35.
27. 27. MORGAN, W.F., & J.E. CLEAVER. 1982. 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanosulfate but not to ultraviolet light. Mutat. Res. 104: 361-366.
28. 28. SCHREIBER, V. et al. 1995. A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage. Proc. Natl. Acad. Sci. USA 92: 4753-4757.
29. 29. JEGGO, P.A. 1998. DNA repair: PARP - another guardian angel? Curr. Biol. 8: R49-R51.