Role of Mismatch Repair in the Fidelity of RAD51- and RAD59-Dependent Recombination in Saccharomyces cerevisiae

Genetics

Volumn 165, Issue 4, 2003, Pages 1733-1744

  Spell, Rachelle Miller ^a   Jinks Robertson, Sue ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; GENE PRODUCT; PROTEIN MLH1; PROTEIN MSH2; RAD51 PROTEIN; RAD59 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME INVERSION; EPISTASIS; FUNGAL STRAIN; FUNGUS MUTANT; GENE FUNCTION; GENE LOSS; GENE SEQUENCE; GENETIC REGULATION; GENETIC STABILITY; GENETIC STRAIN; HOMOLOGOUS RECOMBINATION; MISMATCH REPAIR; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; WILD TYPE;

BASE PAIR MISMATCH; DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; EPISTASIS, GENETIC; FUNGAL PROTEINS; MUTS HOMOLOG 2 PROTEIN; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0346100703     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. ALANI, E., R. A. G. REENAN and R. D. KOLODNER, 1994 Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae, Genetics 137: 19-39.
2. ALTMAN, D. G., 1991 Practical Statistics for Medical Research. Chapman & Hall, New York.
3. AUSUBEL, F. M., R. BRENT, R. E. KINGSTON, D. D. MOORE, J. G. SEIDMAN et al., 1994 Current Protocols in Molecular Biology. John Wiley & Sons, New York.
4. BAI, Y., and L. S. SYMINGTON, 1996 A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae. Genes Dev. 10: 2025-2037.
5. BAI, Y., A. P. DAVIS and L. S. SYMINGTON, 1999 A novel allele of RAD52 that causes severe DNA repair and recombination deficiencies only in the absence of RAD51 or RAD59. Genetics 153: 1117-1130.
6. BARTSCH, S., L. E. KANG and L. S. SYMINGTON, 2000 RAD51 is required for the repair of plasmid double-stranded DNA gaps from either plasmid or chromosomal templates. Mol. Cell. Biol. 20: 1194-1205.
7. BISHOP, A. J., and R. H. SCHIESTL, 2002 Homologous recombination and its role in carcinogenesis. J. Biomed. Biotechnol. 2: 75-85.
8. BOHR, V. A., 2002 Human premature aging syndromes and genomic instability. Mech. Ageing Dev. 123: 987-993.
9. CHEN, W., and S. JINKS-ROBERTSON, 1998 Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. Mol. Cell. Biol. 18: 6525-6537.
10. CHEN, W. and S. JINKS-ROBERTSON, 1999 The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast. Genetics 151: 1299-1313.
11. CROUSE, G. F., 1998 Mismatch repair systems in Saccharomyces cerevisiae, pp. 411-448 in DNA Damage and Repair, Vol. 1: DNA Repair in Prokaryotes and Lower Eukaryotes, edited by J. A. NICKOLOFF and M. F. HOEKSTRA. Humana Press, Totowa, NJ.
12. DATTA, A., A. ADJIRI, L., NEW, G. F. CROUSE, and S. JINKS-ROBERTSON, 1996 Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccharomyces cerevisiae. Mol. Cell. Biol. 16: 1085-1093.
13. DONG, Z., and M. FASULLO, 2003 Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: role of RAD1 and the RAD52 epistasis group genes. Nucleic Acids Res. 31: 2576-2585.
14. EARLEY, M. C., and G. F. CROUSE, 1998 The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 95: 15487-15491.
15. FLORES-ROZAS, H., and R. D. KOLODNER, 1998 The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc. Natl. Acad. Sci. USA 95: 12404-12409.
16. FREEDMAN, J. A., and S. JINKS-ROBERTSON, 2002 Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. Genetics 162: 15-27.
17. GOLDSTEIN, A. L., and J. H. McCUSKER, 1999 Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15: 1541-1553.
18. HARFE, B. D., and S. JINKS-ROBERTSON, 2000a DNA mismatch repair and genetic instability. Annu. Rev. Genet. 34: 359-399.
19. HARFE, B. D., and S. JINKS-ROBERTSON, 2000b Mismatch repair proteins and mitotic genome stability. Mutat. Res. 451: 151-167.
20. HARFE, B. D., B. K. MINESINGER and S. JINKS-ROBERTSON, 2000 Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr. Biol. 10: 145-148.
21. HIGGINS, D. R., S. PRAKASH, P. REYNOLDS and L. PRAKASH, 1983 Molecular cloning and characterization of the RAD1 gene of Saccharomyces cerevisiae. Gene 26: 119-126.
22. HO, Y., A. GRUHLER, A. HEILBUT, G. D. BADER, L. MOORE et al., 2002 Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415: 180-183.
23. IRA, G., and J. E. HABER, 2002. Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol. Cell. Biol. 22: 6384-6392.
24. JOHNSON, R. E., G. K. KOVVALI, L. PRAKASH and S. PRAKASH, 1996 Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability, J. Biol. Chem. 271: 7285-7288.
25. KANG, L. E., and L. S. SYMINGTON, 2000 Aberrant double-strand break repair in rad51 mutants of Saccharomyes cerevisiae. Mol. Cell. Biol. 20: 9162-9172.
26. KOLODNER, R. D., and G. T. MARSISCHKY, 1999 Eukaryotic DNA mismatch repair. Curr. Opin. Genet. Dev. 9: 89-96.
27. KRAMER, W., B. FARTMANN and E. C. RINGBECK, 1996 Transcription of mutS and mutL-homologous genes in Saccharomyces cerevisiae during the cell cycle. Mol. Gen. Genet. 252: 275-283.
28. LEA, D. E., and C. A. COULSON, 1949 The distribution of the numbers of mutants in bacterial populations. J. Genet. 49: 264-285.
29. MALKOVA, A., E. L. IVANOV and J. E. HABER, 1996 Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc. Natl. Acad. Sci. USA 93: 7131-7136.
30. MALONE, R. E., T. WARD, S. LIN and J. WARING, 1990 The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast. Curr. Genet. 18: 111-116.
31. MARSISCHKY, G. T., N. FILOSI, M. F. KANE and R. KOLODNER, 1996 Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev. 10: 407-420.
32. MYUNG, K., A. DATTA, C. CHEN and R. D. KOLODNER, 2001 SGS1, the Saccharomyes cerevesiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat. Genet. 27: 1-4.
33. NICHOLSON, A., M. HENDRIX, S. JINKS-ROBERTSON and G. F. CROUSE, 2000 Regulation of mitotic homeologous recombination in yeast: functions of mismatch repair and nucleotide excision repair genes. Genetics 154: 133-146.
34. PAQUES, F., and J. E. HABER, 1999 Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63: 349-404.
35. PEDRAZZI, G., C. PFRRERA, H. BLASER, P. KUSTER, G. MARRA et al., 2001 Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1. Nucleic Acids Res. 29: 4378-4386.
36. PROLLA, T. A., D.-M. CHRISTIE and R. M. LISKAY. 1994 Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol. Cell. Biol. 14: 407-415.
37. RATTRAY, A. J., and L. S. SYMINGTON, 1995 Multiple pathways for homologous recombination in Saccharomyces cerevisiae. Genetics 139: 45-56.
38. RICHARDSON, C., and M. JASIN, 2000 Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells. Mol. Cell. Biol. 20: 9068-9075.
39. SHERMAN, F., 1991 Getting started with yeast. Methods Enzymol. 194: 3-20.
40. SIGNON, L., A. MALKOVA, M. L. NAYLOR, H. KLIEN and J. E. HABER, 2001 Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol. Cell. Biol. 21: 2048-2056.
41. SPELL, R. M., and S. JINKS-ROBERTSON, 2004 Determination of mitotic recombination rates by fluctuation analysis in Saccharomyces cerevisiae, pp. 3-12 in Genetic Recombination Protocols, edited by A. S. WALDMAN. Humana Press, Totowa, NJ.
42. SUGAWARA, N., F. PAQUES, M. COLAIACOVO and J. E. HABER, 1997 Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc. Natl. Acad. Sci. USA 94: 9214-9219.
43. SUGAWARA, N., G. IRA and J. E. HABER, 2000 DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol. Cell. Biol. 20: 5300-5309.
44. SUNG, P., K. M. TRUJILLO and S. VAN KOMEN, 2000 Recombination factors of Saccharomyces cerevisiae. Mutat. Res. 451: 257-275.
45. SYMINGTON, L. S., 2002 Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev. 66: 630-670.
46. WACH, A., A. BRACHAT, R. POHLMANN and P. PHILIPPSEN, 1994 New heterologous modules for classical or PCR-based gene disruption in Saccharomyces cerevisiae. Yeast 10: 1793-1808.
47. WANG, T.-F., N. KLECKNER and N. HUNTER, 1999 Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc. Natl. Acad. Sci. USA 96: 13914-13919.
48. WELZ-VOEGELE, C., J. E. STONE, P. T. TRAN, H. M. KEARNEY, R. M. LISKAY et al., 2002 Alleles of the yeast PMS1 mismatch-repair gene that differentially affect recombination- and replication-related processes. Genetics 162: 1131-1145.
49. Wu, L., S. L. DAVIES, N. C. LEVITT and I. D. HICKSON, 2001 Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Biol. Chem. 276: 19375-19381.